Respiratory distress syndrome – Page 19 – Communicable Diseases Research

The role of CD4 + FoxP3 + regulatory T cells in the immunopathogenesis of COVID-19: implications for treatment

COVID-19의 면역 병인 발생에서 CD4 + FoxP3 + 조절 T 세포의 역할: 치료에 대한 의미

Review

Published on 2021-04-102022-08-31
Journal: International Journal of Biological Sciences [Category] MERS, SARS, 바이오마커,

Present and future treatment strategies for coronavirus disease 2019

Review

Published on 2021-04-092022-10-31
Journal: Future Journal of Pharmaceutical Sciences [Category] COVID-19,

Clinical features and predictors of severity in COVID-19 patients with critical illness in Singapore

Article

Published on 2021-04-052022-10-29
Journal: Scientific Reports [Category] COVID-19, MERS, SARS,

Evidence for CAT gene being functionally involved in the susceptibility of COVID-19

CAT 유전자가 COVID-19의 감수성에 기능적으로 관련되어 있다는 증거

Review

Published on 2021-04-012022-09-11
Journal: FASEB journal : official publication of the Federa [Category] SARS, 변종,

[키워드] ACE2 ACE2 protein acting addition affecting Analysis binding bioinformatics Bioinformatics analysis candidate gene caused Cell cell membrane coronary pneumonia coronavirus COVID-19 disease distress DNA variants Effectiveness EHF eQTL Evidence expression Extracellular Genes Genetic Genetic variant genetic variants Genome-wide association study GWASs Interaction Intracellular Invasion involved Lungs molecular novel positive correlation potential risk Prognosis Protein Protein binding protein interaction regulate regulated reported respiratory distress Respiratory distress syndrome S protein starting susceptibility syndrome Treatment understanding variant
[DOI] 10.1096/fj.202100008 PMC 바로가기 [Article Type] Review

Clinical characteristics and outcomes of critically ill patients with COVID-19 in Kobe, Japan: a single-center, retrospective, observational study

Observational Study

Published on 2021-04-012022-10-05
Journal: Journal of anesthesia [Category] SARS, 임상,

[키워드] acute respiratory syndrome Bed occupancy Characteristics clinical Clinical characteristics Comorbidity coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patient Critical care Critically ill Critically ill patient described died discharged electrical Follow-up follow-up period hospital Hospitalization ICU initial intensive care interquartile range Invasive mechanical ventilation Japan Kobe median median age medical records men Mortality outbreak outcome Patient remained Respiration Respiration, artificial Respiratory distress syndrome Respiratory distress syndrome, adult retrospective severe acute respiratory syndrome coronavirus 2 single-center strained Survivors the median with COVID-19
[DOI] 10.1007/s00540-021-02897-w PMC 바로가기 [Article Type] Observational Study

The assessment of serum ACE activity in COVID-19 and its association with clinical features and severity of the disease

COVID-19의 혈청 ACE 활성 평가 및 질병의 임상적 특징 및 중증도와의 연관성 평가

Article

Published on 2021-04-012022-09-11
Journal: Scandinavian journal of clinical and laboratory in [Category] MERS, SARS, 바이오마커, 치료기술,

[키워드] ACE ACE activity acute lung injury acute respiratory distress acute respiratory distress syndrome Admission angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme (ACE) ARDS association Asymptomatic autoanalyzer baseline characteristics clinical feature Clinical features comparable Control control group correlation COVID-19 demographic demographic data disease disease severity Effect enrolled enzyme evaluated female groups healthy subject Hemostasis immune responses Inflammation inflammatory markers Laboratory Lung injury marker marker. median median age Mild no correlation nucleic acid on admission pathway Patient patients with COVID-19 radiologic Regulatory respiratory distress Respiratory distress syndrome RT-PCR SARS-COV-2 infection SARS-CoV-2 nucleic acid serum severe pneumonia severity syndrome the disease were recorded
[DOI] 10.1080/00365513.2021.1871641 PMC 바로가기 [Article Type] Article

Viral genomic, metagenomic and human transcriptomic characterization and prediction of the clinical forms of COVID-19

COVID-19의 임상 형태에 대한 바이러스 게놈, 메타게놈 및 인간 전사체 특성화 및 예측

Clinical Trial

Published on 2021-03-292022-09-10
Journal: PLoS Pathogens [Category] SARS, 유전자 메커니즘, 임상, 치료기술,

[키워드] activate activating acute respiratory distress syndrome Acute respiratory failure Analysis antagonists Bacteria candidate Candidates caused Characteristics characterized clinical form collected COVID-19 COVID-19 pneumonia CXCR2 cytokine Diagnosis disease distress ENhance Factor feature female gender form fungi Genetic genomic high mortality rate Host identify IL-8 Immune cell immune cells infiltration Inflammatory response intensive care intensive care unit lower mortality metagenomic Mild Nasopharyngeal swab nasopharyngeal swabs neutrophil neutrophil infiltration outpatients overactive overexpression pandemic parasite parasites pathophysiology pathway Patient patients hospitalized Pneumonia pulmonary disease receptor respiratory respiratory distress Respiratory distress syndrome Respiratory failure respiratory symptom respiratory symptoms resulting SARS-CoV-2 Severe case severe COVID-19 Severe COVID-19 pneumonia severe pneumonia severity severity of COVID-19 shotgun syndrome T helper the disease tissue damage transcript transcriptomic transcriptomics Treatment turn upper respiratory Viral viruses was performed were used
[DOI] 10.1371/journal.ppat.1009416 PMC 바로가기 [Article Type] Clinical Trial

Essentials in saline pharmacology for nasal or respiratory hygiene in times of COVID-19

COVID-19 시대에 비강 또는 호흡기 위생을 위한 식염수 약리학의 필수 요소

Review

Published on 2021-03-272022-08-31
Journal: European Journal of Clinical Pharmacology [Category] SARS, 치료제,

[키워드] 3CLpro ACE2 acute respiratory distress acute respiratory distress syndrome aerosol Aerosols airway airways alveolar analyzed Bronchiolitis Care children chloride ciliary ciliated ciliated epithelium clearance common cold common cold symptoms common cold viruses COVID-19 COVID-19 patient Effect Efficacy epithelial Essential Formal furin gel Hospitalization hygiene hypertonic hypertonic saline hypochlorous acid IMPROVE inhibit initiated interact Interaction Intervention isotonic mechanism Mild moisture Mucociliary clearance myeloperoxidase NaCl nasal nose Outpatient outpatients phagocytic cell Preliminary data promote provide reduce reduction in respiratory Respiratory care respiratory distress Respiratory distress syndrome respiratory epithelia Result Saline SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication seasonal coronavirus seasonal coronaviruses shown sodium sodium channel Sodium chloride supplementary material Symptom symptom onset symptom resolution symptomatic syndrome treatment regimens Vero Vero cells Viral Viral load with COVID-19
[DOI] 10.1007/s00228-021-03102-3 PMC 바로가기 [Article Type] Review

Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19

COVID-19에서 호흡기 위험 증가를 나타낼 수 있는 비만 2형 당뇨병에서 대식세포 활성화 관련 바이오마커 식별

Clinical Trial

Published on 2021-03-192022-09-10
Journal: Scientific Reports [Category] 바이오마커, 임상,

[키워드] activated Activation acute respiratory distress syndrome aptamer ARDS basal basal state baseline Biomarker CD163 CD38 CD80 change changed characterized chemokine chemokines clinical control subject control subjects Conventional COVID-19 CXCL1 CXCL10 CXCL5 CXCL9 cytokine Cytokines determine diabete diabetes Diabetic elevated Endocrine system and metabolic diseases endocrinology ENhance expression Glucose glycemia growth factor Growth factors Hyperactivation identification IFN-γ IL-13 IL-4 immune system individual Infection insulin insulin clamp M1/M2 macrophage M2 macrophage M2 macrophages Macrophage macrophage activation macrophages marker matrix metalloproteinase matrix metalloproteinases mediators MMP7 MMP9 Normalisation not altered obese obesity pilot study plasma Plasma levels plasma protein Protein RANTES registration date released respiratory respiratory distress Respiratory distress syndrome risk serum severity slow subject subjects surface proteins Trial type 2 diabete type 2 diabetes
[DOI] 10.1038/s41598-021-85760-y PMC 바로가기 [Article Type] Clinical Trial

High Incidence of Barotrauma in Patients With Severe Coronavirus Disease 2019

Observational Study

Published on 2021-03-152022-10-04
Journal: Journal of Intensive Care Medicine [Category] MERS, 임상,

[키워드] acute lung injury Adult Airway Pressure artificial average mortality barotrauma cohort study coronavirus disease COVID-19 Critically ill patient demographics disease Evidence-based medicine greater group hospital Hospitalization ICU Illness severity Implications IMV incidence inclusion criteria increased mortality Inflammation Inflammatory response intensive care likelihood Los Angeles lung-protective ventilation median medication NIV no difference pathophysiology Patient patients with ARDS patients with COVID-19 Physiology Pneumonia proportion receiving Respiration Respiratory distress syndrome severe COVID-19 statistical significance sustained therapeutic anticoagulation Treatment Ventilated Ventilation Volume while with COVID-19
[DOI] 10.1177/0885066621989959 PMC 바로가기 [Article Type] Observational Study