Impact of early low-calorie low-protein versus standard-calorie standard-protein feeding on outcomes of ventilated adults with shock: design and conduct of a randomised, controlled, multicentre, open-label, parallel-group trial (NUTRIREA-3)Randomized Controlled Trial Published on 2021-05-112022-10-05 Journal: BMJ Open [Category] SARS, 임상, [키워드] acute phase Admission adult intensive & approved autophagy calory cellular clinical trials Critical Critical care defined dietetics discharge Ethics French functional Hospital-acquired infection hypothesised ICU ICUs Impact include Intensive intensive care Invasive mechanical ventilation management mechanically ventilated patient mechanism metabolic pathway Mortality multicentre nutrition & Open-label outcome outcomes parallel group parallel-group Patient peer-reviewed positive primary end-point primary endpoints Protein protein targets randomised receiving recent Restricting Result secondary Shock submitted Support target therapy Trial vasoactive amine Ventilated [DOI] 10.1136/bmjopen-2020-045041 PMC 바로가기 [Article Type] Randomized Controlled Trial
Impact of Kidney Failure on the Severity of COVID-19Article Published on 2021-05-102022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 28-day mortality age Analysis Arterial hypertension baseline C-reactive protein concentration coronavirus disease Course COVID-19 database demonstrated diagnosed dialysis Factor failure glomerular filtration rate high mortality higher risk identify Impact increased mortality increased risk independent predictor individual individuals kidney Kidney disease Kidney failure Logistic regression analysis malignancy moderate Mortality National neutrophil Older outcome Patient patients patients with COVID-19 Platelet progression renal risk factor SARS-CoV-2 severity of COVID-19 significantly submitted treatment for COVID-19 [DOI] 10.3390/jcm10092042 PMC 바로가기 [Article Type] Article
A UK nationwide study of people with type 1 diabetes admitted to hospital with COVID-19 infectionArticle Published on 2021-05-082022-11-01 Journal: Diabetologia [Category] COVID-19, MERS, SARS, [키워드] Admission age association BMI clinical Clinical characteristics Clinicians collected Complication conducted coronavirus COVID-19 dataset death defined diabete Diabetic died disease Final generate greater hospital Infection Inpatients intensive care laboratory data Local Male sex medication Mortality National audit Patient peer-reviewed positive Prevalence Primary outcome proportion recorded Regression model renal function Result retrospective cohort study risk factor risk of death serum serum creatinine severe COVID-19 submitted supplementary material Type 1 diabete Type 1 diabetes was performed were used with COVID-19 [DOI] 10.1007/s00125-021-05463-x PMC 바로가기 [Article Type] Article
Referral Activity in Three Store-and-Forward Networks during the COVID-19 Coronavirus PandemicResearch Article Published on 2021-05-032022-10-30 Journal: International Journal of Telemedicine and Applications [Category] COVID-19, [키워드] activity build change coronavirus COVID-19 declined Efficiency expand identify International Local network organization pandemic pediatric provided Quantitative Referral regions submitted surgical Travel [DOI] 10.1155/2021/6644648 PMC 바로가기 [Article Type] Research Article
Assessing the impact of COVID-19 on registered interventional clinical trials등록된 중재 임상 시험에 대한 COVID-19의 영향 평가Article Published on 2021-05-012022-09-11 Journal: Clinical and translational science [Category] SARS, 임상, [키워드] Assessing clinical trial clinical trials coronavirus disease Coronavirus disease 2019 COVID-19 pandemic Registered Sponsor submitted translational Trial [DOI] 10.1111/cts.13034 PMC 바로가기 [Article Type] Article
Follow-up of SARS-CoV-2 positive subgroup from the Asymptomatic novel CORonavirus iNFection studyObservational Study Published on 2021-05-012022-10-04 Journal: Journal of medical virology [Category] SARS, 임상, [키워드] acute respiratory syndrome Asymptomatic asymptomatic infections community transmission coronavirus Critical Day fatigue Fever Follow-up headache Hospitalization individual infections initial median muscle ache Nasopharyngeal swab participant Participants participated positive positive test result presenting proportion remained reported reported symptom RT-PCR RT-PCR testing SARS-CoV-2 SARS-COV-2 infection Shortness of breath silent submitted Symptom Transmission Viral load [DOI] 10.1002/jmv.26810 PMC 바로가기 [Article Type] Observational Study
Etiology and clinical characteristics of SARS-CoV-2 and other human coronaviruses among children in Zhejiang Province, China 2017–2019중국 저장성 어린이의 SARS-CoV-2 및 기타 인간 코로나바이러스의 병인 및 임상 특성 2017–2019Research Published on 2021-04-302022-09-10 Journal: Virology Journal [Category] MERS, SARS, 치료기술, [키워드] Acute respiratory infection acute respiratory symptom acute respiratory symptoms Analysis assays Chain Reaction children China circulating circulation Clinical characteristics clinical sample clinical samples common coronavirus country Epidemiology Gender genomes global public health HCoV HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 HCoVs HKU1 Hospitalized children human coronavirus human coronaviruses Infection information Lineage majority multiplex NL63 no significant differences Novel coronavirus novel coronaviruses OC43 occurred Occurrence Other respiratory viruses PCR analysis Phylogenic analysis polymerase chain polymerase chain reaction positive Region respiratory respiratory sample respiratory viruses Result reverse transcription reverse transcription-PCR RNA RT-PCR analysis Sample SARS-CoV-2 screened significant difference species specimen specimens study period submitted supplementary material Surveillance tested Zhejiang [DOI] 10.1186/s12985-021-01562-8 PMC 바로가기 [Article Type] Research
Trends in US Internal Medicine Residency and Fellowship Applications During the COVID-19 Pandemic vs Previous YearsResearch Published on 2021-04-282022-10-29 Journal: JAMA Network Open [Category] Coronavirus, MERS, SARS, [키워드] application COVID-19 cross-sectional evaluate internal Medicine submitted trend Year [DOI] 10.1001/jamanetworkopen.2021.8199 PMC 바로가기 [Article Type] Research
Natural tannin extracts supplementation for COVID-19 patients (TanCOVID): a structured summary of a study protocol for a randomized controlled trialCOVID-19 환자를 위한 천연 탄닌 추출물 보충제(TanCOVID): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-04-282022-09-10 Journal: Trials [Category] MERS, SARS, 임상, [키워드] 1:1 24 hour 24 hours addition Administered administration affected age All trial participants all-cause mortality Alpha alpha error Antibiotic therapy antipyretics assigned assisted ventilation Azithromycin B12 blinded Blinding branch Buenos Aire Buenos Aires can not Chestnut tannins Clinical symptoms clinical trial closure cognitive computer-generated random numbering conditions Consent control group COVID-19 COVID-19 patient criteria cytokine Cytokines Day Decline decrease defined Definition Department described diagnosis of SARS-CoV-2 dietary supplement difference disease dissemination dose double-blind Efficacy element eligibility eligible enrolled Enrollment enrolment epidemiological evaluate excluded fecal Final first dose first visit Gender gut microbiota Hospital de Clínica Hospital de Clínicas Hospital de Clinicas Jose de San Martin hospital discharge Hydroxychloroquine hypersensitivity ICU impaired consciousness increase in indicated Infection Infectious disease Infectious diseases Inflammation inflammatory mediator Inflammatory mediators Informed consent intestinal intestinal permeability invasive ventilation lactating Level Lopinavir mean difference measure mechanical ventilation mediators microbiota modifications molecular natural non-invasive ventilation number objective Older outcome parallel-group parameter participant Participation Patient patients per day Placebo placebo-controlled platform Potential power power of 80% protocol Quebracho tannins randomization Randomized Randomized controlled trial Randomly Real-time PCR receive recruited recruitment Registered Research Ritonavir Sample size SARS-COV-2 infection SARS-CoV2 screened secondary secondary outcome measures severity Standard therapy standard treatment status study participant Study protocol study randomization submitted supplementary material supply tannin tannins therapy time Time frame took place Treatment treatment allocation Trial trial participant Trial registration undergo university Ventilation website [DOI] 10.1186/s13063-021-05281-x PMC 바로가기 [Article Type] Letter
Impact of COVID-19 social-distancing on sleep timing and duration during a university semesterResearch Article Published on 2021-04-262022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] Affect average benefit circadian clock community transmission Course COVID-19 COVID-19 virus cross-sectional directive enrolled Evidence examined expected feature Fitbit heterogeneous homeostatic immune function Impact individual Interpretation less measure mental health positive Questionnaires recommendations remote reported significantly more student Study design submitted thought [DOI] 10.1371/journal.pone.0250793 PMC 바로가기 [Article Type] Research Article