advanced age – Page 2 – Communicable Diseases Research

Changes in life satisfaction, depression, general health and sleep quality of Spanish older women during COVID-19 lockdown and their relationship with lifestyle: an observational follow-up study

Observational Study

Published on 2022-08-242022-10-04
Journal: BMJ Open [Category] SARS, 임상,

Clinical implications of host genetic variation and susceptibility to severe or critical COVID-19

심각하거나 치명적인 COVID-19에 대한 숙주 유전자 변이 및 감수성의 임상적 의미

Review

Published on 2022-08-192022-09-11
Journal: Genome Medicine [Category] SARS, 변종, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 advanced age age allergy Asymptomatic disease clinical clinical implications Clinical management clinical picture Comorbidities convergence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical deficiency develop Effects expected Factor Genetic genetic finding genetic screening Genetic variant Genetic variation healthy individual heterogeneous Host host genetics human immune response IFN-I Immunity implication indicate Infectious disease interferon Male sex malignancies manifestation Mendelian disorder Mendelian disorders modulate pandemic pathogenic variant pathway Pathways Patient Pneumonia predisposition Prevalence rare variant Rare variants risk factor SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe manifestations of COVID-19 shown susceptibility susceptibility loci the interferon TLR7 virus X-linked
[DOI] 10.1186/s13073-022-01100-3 PMC 바로가기 [Article Type] Review

COVID-19 in patients with hematologic malignancy

혈액암 환자의 코로나19

Article

Published on 2022-07-212022-09-11
Journal: Blood [Category] Coronavirus, COVID19(2023년), SARS, 변종, 치료제,

[키워드] active immunization acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 advanced age Antibody Response Antiviral antiviral drug antiviral drugs Clinical efficacy contribute coronavirus COVID-19 COVID-19 in patient develop early treatment early treatment of COVID-19 hematologic Hematologic malignancy heterogeneity high risk illnesses immune response immune system Infectious disease malignancy MONITOR monoclonal antibodies monoclonal antibody mortality rate offered outcome pandemic Patient patients hospitalized Postexposure Prophylaxis predict Prevent reduced risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 vaccine SARS-CoV-2 vaccines severe acute respiratory syndrome Coronavirus severe COVID-19 significantly subtype symptomatic therapy Treatment vaccination Vaccine variants virus
[DOI] 10.1182/blood.2021012251 PMC 바로가기 [Article Type] Article

Genetic polymorphisms associated with susceptibility to COVID-19 disease and severity: A systematic review and meta-analysis

COVID-19 질병 및 중증도에 대한 감수성과 관련된 유전적 다형성: 체계적인 검토 및 메타 분석

Meta-Analysis

Published on 2022-07-062022-09-11
Journal: PLoS ONE [Category] 변종,

[키워드] 95% CI ACE1 advanced age allele alleles analyzed ApoE article association C allele calculated candidate gene CCR5 clinical symptom Clinical symptoms Comorbidities contribute COVID-19 COVID-19 disease COVID-19 infection COVID-19 pathogenesis COVID-19 severity disease eligible fixed form forms Genetic polymorphism genetic polymorphisms Genetic variant genetic variants GWAS HLA HLA-A HLA-B HLA-C identify investigated involved loci Meta-analysis polymorphism Polymorphisms presence of comorbidity random Repository risk searched severe forms of COVID-19 severity of COVID-19 significantly Stata software suggested susceptibility systematic review the disease TMPRSS2 Variation
[DOI] 10.1371/journal.pone.0270627 PMC 바로가기 [Article Type] Meta-Analysis

COVID-19 and solid organ transplantation: Finding the right balance

Review article

Published on 2022-07-012022-10-05
Journal: Transplantation Reviews [Category] COVID19(2023년), SARS, 치료제,

[키워드] Acute kidney injury adjusted advanced age analyzed article articles association Cellular immune response clinical outcomes Comorbidity comparable concerning COVID-19 COVID-19 disease COVID-19 infection COVID-19 pandemic COVID-19 vaccination dysfunction Efficacy Factor finding higher risk humoral immune response Immunity Immunosuppression immunosuppressive include independent risk factor lung transplant Mortality mortality risk objective organ pandemic Patient recipient recipients reported Research Result risk factor Risk factors severe COVID-19 disease severe disease solid organ transplant solid organ transplantation SOT SOT patient systematic review therapy vaccination vaccine immunogenicity was performed
[DOI] 10.1016/j.trre.2022.100710 [Article Type] Review article

Cytokine Profiles Associated With Acute COVID-19 and Long COVID-19 Syndrome

급성 COVID-19 및 장기 COVID-19 증후군과 관련된 사이토카인 프로필

Article

Published on 2022-06-302022-09-11
Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), MERS, SARS, 바이오마커,

[키워드] acute COVID-19 advanced age age clinical conditions clinical presentation Clinical presentations clinical status Cohort Comorbidities Comorbidity COVID COVID-19 COVID-19 treatment cytokine cytokine level cytokine levels cytokine profile Cytokines diagnosed with COVID-19 elevated evaluated Factor group IL-10 IL-17 IL-2 IL-4 IL-6 IL-6 level Long Long COVID-19 marker Mild mild cases moderate no significant difference Patient patients prevention strategies profile risk factor sample collection SARS-CoV-2 serum Serum level severe COVID-19 severity of COVID-19 subject syndrome target TNF-α Treatment younger patient younger patients
[DOI] 10.3389/fcimb.2022.922422 PMC 바로가기 [Article Type] Article

A diminished immune response underlies age-related SARS-CoV-2 pathologies

감소된 면역 반응은 연령 관련 SARS-CoV-2 병리의 기초가 됩니다

Article

Published on 2022-06-282022-09-12
Journal: Cell Reports [Category] COVID19(2023년), MERS, SARS, 진단,

Anti-SARS-CoV2 antibody-mediated cytokine release syndrome in a patient with acute promyelocytic leukemia

급성 전골수구성 백혈병 환자의 항 SARS-CoV2 항체 매개 사이토카인 방출 증후군

Case Reports

Published on 2022-06-132022-09-12
Journal: BMC Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] Activation Acute promyelocytic leukemia acute respiratory distress ADE Administered administration Admission advanced age adverse event Anemia antibody antibody treatment Antibody-dependent enhancement APL approach Bone marrow bruise Case report Clinical deterioration complex Coronavirus disease 2019 COVID-19 symptoms CRS Cytokine release syndrome death Diagnosis disease evidenced exacerbated Factor female hematological high risk highlight IL-10 IL-6 IL-8 immune immune activation immunization Infection Inpatients Laboratory leukemia leukemic life-threatening limit nasal passive immunization Patient positive potential risk radiological rapid increase reported SARS-CoV-2 SARS-CoV-2 RT-PCR SARS-CoV-2 testing SARS-CoV2 serum cytokine severe COVID-19 syndrome tested theoretical risk therapeutic therapy-related immunosuppression throat swab TNFα viral burden viral infection
[DOI] 10.1186/s12879-022-07513-0 PMC 바로가기 [Article Type] Case Reports

Clinical Characteristics and Prognosis of COVID-19 patients in Syria: A cross-sectional multicenter study

Research article

Published on 2022-06-012022-10-05
Journal: Annals of Medicine and Surgery [Category] 바이오마커, 유전자 메커니즘,

[키워드] advanced age age Biomarker Care clinical Clinical characteristics Clinical data Clinical outcome collected Comorbidities Comorbidity COVID-19 COVID-19 mortality COVID-19 patient cross-sectional demographic Diabetes Mellitus died discharged elevated Fever global pandemic Healthcare system high-risk patient highest hospital hypertension International lactate dehydrogenase lung lymphocyte counts majority male material Mortality multicenter multiple comorbidity multivariable analysis National normalized outcome Patient patients polymerase chain positive predictive power Prevalence Prognosis prognostic indicator Prospective Study reduce reported Respiratory failure respiratory rate Result risk risk factor Shortness of breath significantly Stage strained Symptom Syria the disease university hospital White blood cell
[DOI] 10.1016/j.amsu.2022.103816 [Article Type] Research article

A case series of severe breakthrough infections observed in nine patients with COVID-19 in a southwestern German university hospital

독일 남서부 대학 병원에서 9명의 COVID-19 환자에서 관찰된 일련의 심각한 돌발 감염 사례

Article

Published on 2022-06-012022-09-11
Journal: Infection [Category] COVID19(2023년), SARS, 변종,

[키워드] addition advanced age age analyzed avoidance B.1.617.2 behavioural BNT162b2 BNT162b2 vaccines booster vaccination Breakthrough infection cardiorespiratory case sery Comorbidities Complete Course COVID-19 death delta variant disease dose effective Face masks FIVE high risk high-risk area high-risk areas Hospitalization Hospitalized hospitalized patient immunization Increased Infection Intensive intensive care lack measure Measures median median age nine of BNT162b2 Patient patients patients died patients with COVID-19 Pfizer-BioNTech preventive measures Protective question raise risk factor Risk factors SARS-CoV-2 suffered symptom onset Travel two patients U/mL university hospital vaccination Vaccine Vaccine breakthrough
[DOI] 10.1007/s15010-022-01797-9 PMC 바로가기 [Article Type] Article