Relative sensitivity of anterior nares and nasopharyngeal swabs for initial detection of SARS-CoV-2 in ambulatory patients: Rapid review and meta-analysis외래 환자에서 SARS-COV-2의 초기 탐지를위한 전방 나르 및 비 인두 면봉의 상대적 민감도 : 빠른 검토 및 메타 분석Review Published on 2021-07-202022-09-10 Journal: PLoS ONE [Category] SARS, 진단, 치료기술, [키워드] ambulatory patients assessments bioRxiv Chain Reaction Characteristics Confusion diagnosing Diagnosis diagnosis of SARS-CoV-2 Extracted for inclusion gold gold standard greater heterogeneity Infection initial less medRxiv Meta-analysis nare nasal nasal swab nasal swabs nasopharyngeal specimen Nasopharyngeal swab nasopharyngeal swabs Negative predictive value Patient performed Personal protective equipment Polymerase chain reaction testing Population predictive values PROSPERO provided Rapid reduced reference standard Registered relative SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections sensitivity specimen Study design study outcomes subject Swab [DOI] 10.1371/journal.pone.0254559 PMC 바로가기 [Article Type] Review
Longitudinal monitoring of laboratory markers characterizes hospitalized and ambulatory COVID-19 patients실험실 마커의 종 방향 모니터링은 입원 및 외래 Covid-19 환자를 특징으로합니다.Article Published on 2021-07-142022-09-10 Journal: Scientific Reports [Category] SARS, 바이오마커, 임상, 진단, 치료기술, 치료법, [키워드] acute phase Admission ambulatory patient ambulatory patients C-reactive protein cardiac cardiac troponin Cardiac troponin I Clinical course COVID-19 COVID-19 patient COVID-19 patients Critically ill critically ill COVID-19 patients CRP D-dimer determine Diagnostic markers Early detection ferritin form home quarantine Hospitalized hospitalized patient hospitalized patients Human IL-6 IL-6 level IL-6 levels interleukin interleukin-6 Laboratory longitudinal marker mild COVID-19 patient moderate moderate to severe myocardial injury on admission Patient patient groups patients positive Predictive Predictive markers Prognosis Prognostic markers recruitment SARS-CoV-2 severe forms of COVID-19 significant decrease troponin I were measured [DOI] 10.1038/s41598-021-93950-x PMC 바로가기 [Article Type] Article
Combined Metabolic Activators Accelerates Recovery in Mild‐to‐Moderate COVID‐19결합 된 대사 활성화 제는 온화한 중등도의 CovID -19에서 회복을 가속화합니다Clinical Trial Published on 2021-06-282022-08-13 Journal: Advanced Science [Category] MERS, 임상, [키워드] accelerate activator adenine administration ambulatory patient ambulatory patients Amino acid antioxidant antioxidant metabolism changes Clinical data clinical trial CMAs Combined combined metabolic activator combined metabolic activators complete recovery comprehensive analysis conducted COVID‐19 COVID‐19 patients deficiencies deficiency double‐blinded phase effective glutathione glutathione metabolism immune response IMPROVE include Infection Inflammation inflammatory proteomics investigated l ‐carnitine l ‐carnitine tartrate lead lipid metabolism metabolic metabolic abnormalities metabolic function metabolism metabolite metabolites metabolomics mitochondrial mitochondrial dysfunction mixture NAD+ nicotinamide nicotinamide adenine dinucleotide nicotinamide riboside omics data Open‐label phase Patient patients treated Phase 2 phase 3 trial Phase 3 trials phase‐2 phase‐3 Placebo placebo group Placebo‐controlled Plasma level Plasma levels plasma metabolome plasma metabolomics precursor Protein proteome proteomics regulate respiratory respiratory problems reveal Safe salt shown significantly significantly shorter therapeutic regime therapeutic strategy Treatment [DOI] 10.1002/advs.202101222 PMC 바로가기 [Article Type] Clinical Trial
Web-based, rapid and contactless management of ambulatory patients for SARS-CoV-2-testingSARS-COV-2 테스트를위한 외래 환자의 웹 기반, 신속하고 비접촉식 관리Research Published on 2021-06-072022-09-01 Journal: BMC Infectious Diseases [Category] MERS, 진단, [키워드] ambulatory patient ambulatory patients among others automated common cold communication concerning Contact cough COVID-19 COVID-19 pandemic Digital medicine duration of symptom effective facility FIVE headache implementation indicated indication indications information management mass mass casualty incident medical history occurred Outpatient outpatient appointment outpatients pandemic Patient per day physician potential risk provide provides QR code rapid response reduced representing Result retrieved SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2 test SARS-CoV-2 testing SARS-CoV-2 testing strategy scheduling Seven sore throat supplementary material Support Symptom Symptoms test results the SARS-CoV-2 transmission of SARS-CoV-2 Travel Triage university university hospital was used Web Web-based patient management [DOI] 10.1186/s12879-021-06249-7 PMC 바로가기 [Article Type] Research
Breast Cancer Screening during COVID-19 Emergency: Patients and Department Management in a Local ExperienceArticle Published on 2021-05-062022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] activity adopted ambulatory patients applied article Asymptomatic biopsies biopsy body temperature Breast Breast cancer Breast cancer screening checked Confirmed COVID-19 COVID-19 infection Department experience guideline hospital implementation mandatory pandemic Patient patient population performed protocol public health emergency questionnaire radiological Safe screened Screening subsequent symptomatic were infected [DOI] 10.3390/jpm11050380 PMC 바로가기 [Article Type] Article
Neutralizing Antibody Therapeutics for COVID-19COVID-19에 대한 중화 항체 치료제Review Published on 2021-04-072022-09-01 Journal: Viruses [Category] SARS, 변종, 진단, 치료제, [키워드] administration ambulatory patient ambulatory patients Antiviral Antiviral treatment authorization bamlanivimab Casirivimab Clinical management COVID-19 COVID-19 pandemic COVID-19 patient drug Drug administration effective Emergency Emergency use authorization etesevimab European Medicines Agency food global public health high risk highlighting Hospitalized hospitalized patient hospitalized patients Imdevimab IMPROVE monotherapy mutant NAb NAbs neutralizing antibody Occurrence oxygen Patient progressed Prophylactic Prophylaxis Randomized controlled trial resistance risk SARS-CoV-2 SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody severe COVID-19 severe disease subsequent supplemental oxygen susceptibility Therapeutic strategies Therapeutics Treatment US Food and Drug Administration variant with COVID-19 [DOI] 10.3390/v13040628 PMC 바로가기 [Article Type] Review
Performance of Saliva Specimens for the Molecular Detection of SARS-CoV-2 in the Community Setting: Does Sample Collection Method Matter?커뮤니티 환경에서 SARS-CoV-2의 분자 검출을 위한 타액 표본의 성능: 샘플 수집 방법이 중요합니까?Article Published on 2021-03-192022-09-11 Journal: Journal of Clinical Microbiology [Category] SARS, 진단, 치료기술, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 ambulatory patient ambulatory patients Asymptomatic asymptomatic individual Asymptomatic individuals best coefficient collected Collection Community community setting conditions conducted confidence interval coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cycle threshold detection diagnosing diagnostics higher risk identify individual intervals median age Nasopharyngeal swab nasopharyngeal swabs NPs Oropharyngeal Outpatient outpatients pair Patient PCR performance positive primary care centers Prospective Study ranged respiratory reverse transcriptase reverse transcriptase PCR RT-PCR Saliva saliva samples saliva specimen saliva specimens Sample SARS-CoV-2 sensitivities sensitivity severe acute respiratory syndrome Coronavirus specimen symptomatic individual symptomatic individuals tested Transmission was performed [DOI] 10.1128/JCM.03033-20 PMC 바로가기 [Article Type] Article
Ambulatory Patients with Cardiometabolic Disease and Without Evidence of COVID-19 During the Pandemic. The CorCOVID LATAM StudyOriginal Research Published on 2021-02-172022-10-31 Journal: Global Heart [Category] COVID-19, MERS, [키워드] age alcohol ambulatory ambulatory patient ambulatory patients cardiometabolic disease cardiovascular disease Care changes in clinical evidence conducted Contact Coronary artery disease country COVID-19 COVID-19 pandemic cross-sectional survey Depression depressive symptom enrolled evidence of healthcare heart failure investigated Latin Latin America less males medication mental health Multivariate analysis pandemic Patient patients physical activity prevalent psychological symptoms recommendation reported SARS-CoV-2 SARS-CoV-2 pandemic social determinants study population Treatment variable vascular disease [DOI] 10.5334/gh.932 PMC 바로가기 [Article Type] Original Research
Effect of High-Dose Zinc and Ascorbic Acid Supplementation vs Usual Care on Symptom Length and Reduction Among Ambulatory Patients With SARS-CoV-2 Infection The COVID A to Z Randomized Clinical Trial고용량 아연 및 아스코르빈산 보충제 대 일반 관리가 SARS-CoV-2 감염이 있는 보행 환자의 증상 기간 및 감소에 미치는 영향 COVID A to Z 무작위 임상 시험Randomized Controlled Trial Published on 2021-02-122022-08-13 Journal: JAMA Network Open [Category] MERS, 임상, [키워드] acid acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adverse effect adverse effects age ambulatory ambulatory patient ambulatory patients ascorbic acid benefit Care Chain Reaction clinical clinical trial Combination conditional power conducted coronavirus cough COVID cumulative deaths decrease diagnosed diagnosis of SARS-CoV-2 duration of symptom early treatment Effect end point enrolled Evidence fatigue Fever finding group groups health system High-dose hospitalizations Identifier Importance Infection Length mitigate multicenter no significant difference not affect objective Open-label open-label trial participant Patient Point polymerase chain polymerase chain reaction prescribed medications primary end point progression Randomized randomized clinical trial receive receiving reduce reduction in Registration Relevance required respiratory Result SARS-CoV-2 SARS-COV-2 infection secondary secondary outcome Secondary outcomes setting severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity Shortness of breath significant difference significantly Standard of care Symptom symptom severity score Symptoms Treatment treatment groups Trial Trial registration usual care women Zinc zinc gluconate [DOI] 10.1001/jamanetworkopen.2021.0369 PMC 바로가기 [Article Type] Randomized Controlled Trial
Structural Mapping of Mutations in Spike, RdRp and Orf3a Genes of SARS-CoV-2 in Influenza Like Illness (ILI) Patients인플루엔자 유사 질병(ILI) 환자에서 SARS-CoV-2의 스파이크, RdRp 및 Orf3a 유전자 돌연변이의 구조적 매핑Article Published on 2021-01-192022-09-10 Journal: Viruses [Category] 치료기술, [키워드] Affect ambulatory patients Amino acid amino acid substitution Analysis binding site cause characterized China clade Clustering collected community transmission confirmation conformational change COVID-19 COVID-19 case COVID-19 illness D614G epidemiological link Extracellular followed by functional ILI illness incidence independent indicated Influenza influenza like illness influenza vaccine isolate Like mapping membrane mild COVID-19 illness mitigate Nasopharyngeal swab nasopharyngeal swabs next generation sequencing NGS oligomerization overlap P323L pandemic Patient PCR Public health interventions Q57H RdRP replaced SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 virus Sequencing silent silent transmission spike spike gene Substitution Surveillance thought Transcription Transmission transmission of SARS-CoV-2 virus virus replication [DOI] 10.3390/v13010136 PMC 바로가기 [Article Type] Article