Bioinformatic

[키워드] Acute cardiac injury Analysis Autopsy Bioinformatic bioinformatic analysis bioinformatics calpain calpain small subunit 1 (capn4) CAPNS1 cardiac cardiac injury conducted COVID-19 cytoplasmic Cytoscape dataset datasets dead DEGs DESeq2 develop diabete diabetes differentially expressed gene Differentially expressed genes down-regulated endopeptidase event events exhibited expression profile expression profiles function functions Gene ontology healthy heart hearts highlight homologous Hospitalized Human hydrolysis hydrolyzed identification identify Infection Interaction Kyoto leads less mechanism membrane mice Mitochondria molecular Mybpc3 Myocardium NCBI-Gene NCBI-GEO nuclear translocation overlapping pathogenic pathway patients with SARS-CoV-2 performed PPI PPI network prognostic progression protein-protein interaction reduced RNA-sequencing SARS-COV-2 infection self-protective role Serine Signaling significantly significantly increased small subunit specimen substrate syndrome T2D therapy Tnni3 Transcription transcriptional change transcriptional level Transcriptional upregulation transcriptomics Type type 2 diabetes unique up-regulated with COVID-19
[DOI] 10.3389/fendo.2022.801260 PMC 바로가기 [Article Type] Endocrinology