Transient disappearance of CD19 + /CD5 + B‐lymphocyte clone in peripheral blood in a patient with CLL during SARS‐CoV‐2‐related mild diseaseCase Report Published on 2021-06-222022-11-01 Journal: Clinical Case Reports [Category] COVID-19, [키워드] CD19 CD19+/CD5+ clone clinical marker CLL clone COVID‐19 disease evaluated Lymphocytic leukemia lymphopenia Mild Patient Peripheral blood Prognosis SARS‐CoV‐2 to define Transient Treatment [DOI] 10.1002/ccr3.4238 PMC 바로가기 [Article Type] Case Report
Lymphocyte–monocyte–neutrophil index: a predictor of severity of coronavirus disease 2019 patients produced by sparse principal component analysis림프구 - 모노 세포 - 중성 유리 지수 : 코로나 바이러스 질병의 중증도 예측 인자 2019 스 희미한 주요 성분 분석에 의해 생성 된 환자Research Published on 2021-06-042022-09-10 Journal: Virology Journal [Category] MERS, SARS, 바이오마커, [키워드] albumin Analysis AUC best classical clinical clinical marker Cohort cohorts comparable component condition coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients decision curve analysis disease severity effective Efficiency evaluated independent lymphocyte moderate neutrophil Neutrophil-to-lymphocyte ratio Odds ratio Patient patients PC1 prediction predictor Principal component principal component analysis principal components produced Receiver operator characteristic recognize Result robust SARS-CoV-2 severity significantly supplementary material total variance training training data validation validation cohort was performed were used [DOI] 10.1186/s12985-021-01561-9 PMC 바로가기 [Article Type] Research
Association Between Treatments and Short-Term Biochemical Improvements and Clinical Outcomes in Post-Severe Acute Respiratory Syndrome Coronavirus-2 Inflammatory Syndrome중증 후 급성 호흡기 증후군 코로나바이러스-2 염증 증후군의 치료와 단기 생화학적 개선 및 임상 결과 사이의 연관성Observational Study Published on 2021-05-012022-09-12 Journal: Pediatric critical care medicine : a journal of th [Category] SARS, 임상, 진단, [키워드] acute respiratory syndrome Administered analyzed benefit biochemical biologic agent C-reactive protein changes in children clinical clinical guideline clinical marker Clinical outcome clinical trial clinician collected combinations Coronavirus-2 Course decrease determine Effect Evidence Guidance identify Immunoglobulin immunomodulator improvement Inflammation Inflammatory Inflammatory marker lack linear Lymphocyte count measurement over Patient pediatric Platelet Propensity score receive recommendation respiratory robust Steroids study period syndrome treated Treatment treatment guideline were used [DOI] 10.1097/PCC.0000000000002728 PMC 바로가기 [Article Type] Observational Study
Time-to-Death Longitudinal Characterization of Clinical Variables and Longitudinal Prediction of Mortality in COVID-19 Patients: A Two-Center StudyMedicine Published on 2021-04-292022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome analyzed AUC biochemical build C-reactive protein Cell Characteristics characterization clinical clinical marker clinical variable clinical variables cohort study Coronavirus-2 COVID-19 D-dimer death demonstrated Deterioration discharge evaluated fluctuation Hospital admission Intervention lactate dehydrogenase longitudinal Lymphocytes measurement Mortality New York non-survivor Non-survivors outcome Patient performance physiological polymerase chain positive predicted prediction Predictive predictor Prevent procalcitonin progression provide receiver operating characteristics respiratory rate SARS-CoV-2 survivor Survivors Temporal Tongji Hospital trend university variable were used with COVID-19 Wuhan, China [DOI] 10.3389/fmed.2021.661940 PMC 바로가기 [Article Type] Medicine
HLA-A*11:01:01:01, HLA-C*12:02:02:01-HLA-B*52:01:02:02, Age and Sex Are Associated With Severity of Japanese COVID-19 With Respiratory FailureImmunology Published on 2021-04-222022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome age allele Analysis association Asymptomatic case can be used case-control analysis center clinical marker clinician Comorbidities confounding factor coronavirus coronavirus disease COVID-19 decrease develop Diagnosis disease eight failure global health Haplotype help highest HLA HLA allele HLA gene hospitalized COVID-19 patients identify infected individual Japan Japanese knowledge majority Medicine Mild mild symptoms Mortality Next-generation sequencing outbreak pandemic Patient recruited remained respiratory risk SARS-CoV-2 sensitivity severe COVID-19 severe respiratory symptoms severity of COVID-19 Sex significantly specificity susceptibility genes susceptible Tokyo utility virus was performed WHO with COVID-19 World Health Organization [DOI] 10.3389/fimmu.2021.658570 PMC 바로가기 [Article Type] Immunology
Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patientsArticle Published on 2021-03-182022-10-29 Journal: Scientific Reports [Category] COVID-19, [키워드] Amino acid amino acid metabolism Analysis changes in clinical marker correlated COVID-19 patient disease severity help highlighting hypoxia hypoxic conditions lung damage maintain metabolite metabolomics Mild oxygen homeostasis oxygen levels oxygen saturation Patient profile reveal SARS-COV-2 infection serum viral infection [DOI] 10.1038/s41598-021-85788-0 PMC 바로가기 [Article Type] Article
COVID-19 engages clinical markers for the management of cancer and cancer-relevant regulators of cell proliferation, death, migration, and immune responseCOVID-19는 암 관리 및 세포 증식, 사멸, 이동 및 면역 반응의 암 관련 조절자를 위한 임상 마커를 사용합니다.Article Published on 2021-03-042022-08-31 Journal: Scientific Reports [Category] SARS, 바이오마커, 치료법, [키워드] biological processe biological processes Cancer cancer patient Cancer patients Cancer therapy Cell cell proliferation clinical clinical decision clinical marker clinical markers clinical observations COVID-19 death Diagnosis diagnostic Diversity EGF endothelial engage Engagement epidemiological epithelial FGF immune response immune system immune system cells infected with SARS-CoV-2 initiated Intersection management marker mechanism Migration modifications network network analysis observation pathway Pathways predicted Prognosis provide rationale regulator Regulatory Regulatory networks retrieved SARS-CoV-2 smooth muscle Support Symptom TGFβ Treatment Tumor tumor suppressors tumorigenesis understanding VEGF virus was used [DOI] 10.1038/s41598-021-84780-y PMC 바로가기 [Article Type] Article
Observational Study of Chlorpromazine in Hospitalized Patients with COVID-19Observational Study Published on 2021-03-012022-10-05 Journal: Clinical drug investigation [Category] SARS, 임상, [키워드] 95% CI 95% confidence interval adjusted Analysis Anti-inflammatory effects Antiviral AP-HP assistance association baseline Characteristics chlorpromazine clinical marker conducted coronavirus disease COVID-19 Cox regression Cox regression model daily dose death defined disease severity Endpoint Follow-up hazard ratio Hospitalization Hospitalized hospitals ICU ICUs indicated Inpatient intensive care unit Mortality multicenter Multiple multivariable Cox regression occurred over Paris Patient patients hospitalized performed positive primary analysis primary endpoint Probability psychotropic medications reduced Retrospective study sensitivity analysis Standard deviation suggested university Weighting with COVID-19 [DOI] 10.1007/s40261-021-01001-0 PMC 바로가기 [Article Type] Observational Study
Point-of-care lung ultrasound for the assessment of pneumonia: a narrative review in the COVID-19 eraReview Article–Respirology Published on 2021-01-132022-10-30 Journal: Journal of Medical Ultrasonics (2001) [Category] COVID-19, [키워드] accumulate Accuracy Bacterial carried Case report chest X-ray clinical marker Combination community-acquired pneumonia consolidation coronavirus COVID-19 demonstrated Deterioration Diagnosis diagnostic expected initial intensive care unit knowledge lung Lung ultrasound majority management mechanically ventilated patient Multiple observational study Patient Pneumonia point-of-care positive Prevalence Prospective Prospective Study sensitivity Significant the disease Ventilator-associated pneumonia Viral pneumonia [DOI] 10.1007/s10396-020-01074-y PMC 바로가기 [Article Type] Review Article–Respirology
Preemptive interleukin-6 blockade in patients with COVID-19Article Published on 2020-10-082022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 치료제, [키워드] antibody anticipated Biological blockade C-reactive protein catastrophic clinical manifestation clinical marker collected Comorbidity consequence contributing to COVID-19 criteria Cytokine release syndrome Cytokine storm D-dimer death disease evaluated Final Gender Health care humanized implicated In-hospital inclusion criteria Infectious diseases initial interleukin-6 key factor monoclonal Nasopharyngeal swab nasopharynx non-responder outcome outcomes Patient patients patients hospitalized patients with COVID-19 plasma biomarker predicted predictor predictors Prevent profile receptor Responder Safe severely ill patients Signaling SOFA SOFA score Stage Systolic blood pressure Temporal the SARS-CoV-2 therapy Tocilizumab treated with COVID-19 [DOI] 10.1038/s41598-020-74001-3 PMC 바로가기 [Article Type] Article