Re-orienting anti-malarial drug development to better serve pregnant women임산부에게 더 나은 서비스를 제공하기 위해 말라리아 치료제 개발 방향 재조정Article Published on 2022-04-122022-09-11 Journal: Malaria Journal [Category] Coronavirus, 말라리아, 신약개발, [키워드] addressed Administered affecting amplified anti-malarial drug Antimalarial drugs approach Breastfeeding can not change clinical trial collected Comment Community COVID-19 pandemic D Data collection Dosing drug resistance effective Equity in R& first trimester Health help Inclusion Inclusion of women individual Infectious disease Infectious diseases malaria Malaria in pregnancy medication medications Medicine Medicines New New medicines. pathway Plasmodium Population Pregnancy pregnant pregnant women Prevent PROTECT recommendation Regulatory responsible rising risk Safe Stage Support translational treat [DOI] 10.1186/s12936-022-04137-2 PMC 바로가기 [Article Type] Article
Regulation of Proinflammatory Molecules and Tissue Factor by SARS-CoV-2 Spike Protein in Human Placental Cells: Implications for SARS-CoV-2 Pathogenesis in Pregnant Women인간 태반 세포에서 SARS-CoV-2 스파이크 단백질에 의한 전염증성 분자 및 조직 인자의 조절: 임산부의 SARS-CoV-2 발병에 대한 의미Article Published on 2022-04-072022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료기술, [키워드] ACE2 binding CCL2 CCL5 Cell cell line chemokine chemokines coagulation cascade complications contribute CTBs CXCL10 CXCL9 cytokine Cytokine storm Cytokines dysfunction elevate elevated ELISA Endothelial cell endothelial cells Express expression extrinsic Factor first trimester FUSE host cells Human IL-6 IL-8 immunohistochemical staining immunoreactivity Impaired pregnancy indicated induce infect Infection molecule outcomes Placenta placental placental dysfunction placental thrombosis pregnancies Pregnancy pregnancy complications pregnant women pro-inflammatory cytokine pro-inflammatory cytokine release pro-inflammatory cytokines proinflammatory Proinflammatory cytokine proinflammatory cytokines qPCR S-protein SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein secreted significantly higher specimen spike Spike protein stromal cell stromal cells syncytiotrophoblast term the cytokine storm thrombosis tissue Tissue Factor TMPRSS2 TMPRSS2 level TMPRSS2 levels treated trophoblast Viral RNA virus was measured was performed were measured [DOI] 10.3389/fimmu.2022.876555 PMC 바로가기 [Article Type] Article
Obstetric and neonatal outcomes after SARS-CoV-2 infection in the first trimester of pregnancy: A prospective comparative study임신 1분기 SARS-CoV-2 감염 후 산과 및 신생아 결과: 전향적 비교 연구Observational Study Published on 2022-02-012022-09-11 Journal: The journal of obstetrics and gynaecology research [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] abortion acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission adverse event antibody Antibody titer APGAR score Asymptomatic Birth Blood Cohort cohort study Composite Cord blood coronavirus coronavirus disease Coronavirus disease-19 COVID-19 defined evaluate events excluded first trimester growth higher risk hospital Hospital admission IgG antibodies Infection intensive care intrauterine growth restriction Maternal membranes Nasopharyngeal swab Neonatal Newborn Obstetric outcome Patient patients Pneumonia positive preeclampsia Pregnancy preterm delivery Primary outcome prospective observational cohort rupture SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus significantly more Stillbirth Symptom symptomatic tested Transmission vertical transmission was performed were recorded women [DOI] 10.1111/jog.15105 PMC 바로가기 [Article Type] Observational Study
Prevalence of antibodies against SARS-CoV-2 among pregnant women in Norway during the period December 2019 through December 20202019년 12월부터 2020년 12월까지 노르웨이 임산부의 SARS-CoV-2에 대한 항체 유병률Short Paper Published on 2022-01-132022-09-11 Journal: Epidemiology and Infection [Category] 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted analysed antenatal care antibodies antibody Antigen Compliance coronavirus detect DiaSorin Elecsy Elecsys Epidemiology estimating explained first trimester hospital IgG immunoassay incidence modelling Norway Occurrence positive test result pregnant pregnant women Prevalence prevalence of disease preventive measure preventive measures remained respiratory Roche Diagnostics S1/S2 S2 protein SARS SARS CoV SARS CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid SARS-CoV-2 virus sera serological seropositive serum severe acute respiratory syndrome Coronavirus study period syphilis test results the epidemic the SARS-CoV-2 virus women [DOI] 10.1017/S0950268822000073 PMC 바로가기 [Article Type] Short Paper
First-Trimester SARS-CoV-2 Infection: Clinical Presentation, Inflammatory Markers, and Obstetric Outcomes임신 초기 SARS-CoV-2 감염: 임상 발표, 염증 표지자 및 산과적 결과Multicenter Study Published on 2022-01-012022-09-11 Journal: Fetal diagnosis and therapy [Category] SARS, 바이오마커, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Asymptomatic blood count clinical Complication complications coronavirus COVID-19 Doppler evaluated ferritin first trimester growth factor IL-6 increased risk Infection infections Inflammatory Inflammatory marker inflammatory markers lymphopenia Mild multicenter multicenter study not increased Obstetric Obstetric outcomes outcome performed plasma protein positive preeclampsia Pregnancy presentation Prevalence respiratory SARS-CoV-2 SARS-COV-2 infection second serologic testing severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 symptomatic tyrosine uterine uterine artery women [DOI] 10.1159/000523974 PMC 바로가기 [Article Type] Multicenter Study
Passive Immunity to SARS-CoV-2 at Birth Induced by Vaccination in the First Trimester of Pregnancy임신 첫 3개월 동안 예방 접종으로 유도된 출생 시 SARS-CoV-2에 대한 수동 면역Case Reports Published on 2021-12-032022-09-12 Journal: International Journal of Environmental Research an [Category] SARS, 진단, [키워드] affecting anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies anti-SARS-CoV-2 IgG antibody approach automated Birth Blood carried collected Complete COVID-19 infection DELFIA described Filter Paper first trimester Health IgG antibodies IgG antibody immune response immune system immunoassay induced invasive life Mild MONITOR mother Newborn newborn SARS-CoV-2 immunity Passive performed position Pregnancy pregnant women SARS-CoV-2 screening program Serological assay serological test solid phase spike-specific T cells trimester vaccination vaccination in pregnancy viral infection virus woman [DOI] 10.3390/ijerph182312789 PMC 바로가기 [Article Type] Case Reports
Emergence and spread of the potential variant of interest (VOI) B.1.1.519 of SARS-CoV-2 predominantly present in Mexico멕시코에 주로 존재하는 SARS-CoV-2의 잠재적 관심 변종(VOI) B.1.1.519의 출현 및 확산Article Published on 2021-11-012022-09-11 Journal: Archives of Virology [Category] SARS, 변종, [키워드] Affect B.1.1.7 B.1.351 country dominant Effectiveness emergence first trimester Lineage Mutation P681H receptor Receptor binding reduced reported SARS-CoV-2 SARS-CoV-2 variants Spike protein Spread Substitution T478K the spike protein Transmissibility Vaccine variant variants of concern virus WHO [DOI] 10.1007/s00705-021-05208-6 PMC 바로가기 [Article Type] Article
First trimester pregnancy outcomes in a large IVF center from the Lombardy County (Italy) during the peak COVID-19 pandemicObservational Study Published on 2021-08-162022-10-04 Journal: Scientific Reports [Category] MERS, 임상, [키워드] analysed Analysis ART Asymptomatic biochemical clinical COVID COVID-19 COVID-19 pandemic Diseases ectopic Effect Embryo endocrinology evaluate first trimester Health care Italian Italy lockdown lombardy no difference Non-COVID-19 Oocyte outcome pandemic Pandemics performed Pregnancy reproduction risk Support treated [DOI] 10.1038/s41598-021-96134-9 PMC 바로가기 [Article Type] Observational Study
COVID-19 and cause of pregnancy loss during the pandemic: A systematic review코로나19와 대유행 기간 중 유산의 원인: 체계적인 검토Meta-Analysis Published on 2021-08-112022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] abortion acute respiratory syndrome article articles association Case report Case series case sery collected Complication complication of COVID-19 coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 infection COVID-19 pandemic database Effect eligible Evidence evidence of fetal fetal growth retardation fetus first trimester growth growth retardation Hospital stay include increased risk induce Infection Inflammation miscarriage mother pandemic placental insufficiency positive test result Pregnancy pregnant female pregnant females report respiratory Result SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 systematic review test result Transmission Two patient two patients vertical transmission viral infection virus Web of Science with COVID-19 [DOI] 10.1371/journal.pone.0255994 PMC 바로가기 [Article Type] Meta-Analysis
Fetal and placental infection with SARS-CoV-2 in early pregnancy임신 초기 SARS-CoV-2에 의한 태아 및 태반 감염Case Reports Published on 2021-07-012022-09-11 Journal: Journal of medical virology [Category] SARS, 치료법, [키워드] accompanied acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Chain Reaction clinician consequence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection double-stranded RNA dsRNA early pregnancy fetal fetus first trimester histological histological examination Hyperinflammatory immunofluorescence immunohistochemistry in some Infection Inflammation kidney lung management Microscopy miscarriage nucleocapsid protein organ organs outcomes pandemic Particle Particles Placenta placental Placental infection polymerase chain polymerase chain reaction positive Pregnancy pregnant women produced Prominent Protein provided Quantitative Replication responsible reverse transcription RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid SARS-CoV-2 protein severe acute respiratory syndrome Coronavirus target targets tissues Transmission Viral RNA [DOI] 10.1002/jmv.26965 PMC 바로가기 [Article Type] Case Reports