Persistence of Immune Response in Health Care Workers After Two Doses BNT162b2 in a Longitudinal Observational Study종단 관찰 연구에서 BNT162b2 2회 투여 후 의료 종사자의 면역 반응 지속Observational Study Published on 2022-03-042022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 임상, 진단, 치료기술, [키워드] age All participants Analysis antibody average binding binding antibody BNT162b2 BNT162b2 vaccine booster dose booster doses booster vaccinations Care cellular Cellular immune response Course COVID-19 disease declining described detectable dose Efficacy evaluated Follow-up groups Health Health care Health care worker hospital humoral humoral and cellular immunity humoral immune response immune response immunological Immunological memory individual interferon Interferon-gamma longitudinal mRNA mRNA-based vaccine Neutralizing antibodies obesity observational study of BNT162b2 Older age participant Participants peptide peptides persistence Pfizer Quantitative response response rate resulting SARS-CoV-2 SARS-COV-2 infection second dose semi-quantitative Serological testing shown vaccination vaccination. Vaccine worker [DOI] 10.3389/fimmu.2022.839922 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2-specific B- and T-cell immunity in a population-based study of young Swedish adults젊은 스웨덴 성인에 대한 인구 기반 연구에서 SARS-CoV-2에 특이적인 B 및 T 세포 면역Clinical Trial Published on 2022-01-012022-09-11 Journal: The Journal of Allergy and Clinical Immunology [Category] MERS, SARS, 임상, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adults age allergy assessment Asthma Asymptomatic asymptomatic infections Barn binding domain birth cohort body mass body mass index cellular immunity Characteristics Cohort conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease detectable disease Effects ELISA ELISPOT Factor Follow-up Health humoral humoral and cellular immunity IgA IgE IgG IgG titer IgG titers IgM Immunity IMPROVE indicate individual Infection memory B memory B cells memory response memory T memory T cells Mild mild to moderate mild to moderate disease milieu moderate disease participant population-based cohort positive public transport respiratory rhinitis risk Risk factors SARS-CoV-2 SARS-COV-2 infection seronegative seropositive seropositive subject Seropositivity severe acute respiratory syndrome Coronavirus Sex smoking specific IgM subject subjects subpopulation subset Swedish Symptom symptomatic and asymptomatic T cells T-cell T-cell immunity T-cell Response T-cell responses Transport vaccination whom Young adults. [DOI] 10.1016/j.jaci.2021.10.014 PMC 바로가기 [Article Type] Clinical Trial
Widely heterogeneous humoral and cellular immunity after mild SARS-CoV-2 infection in a homogeneous population of healthy young men균질한 건강한 젊은 남성 집단에서 가벼운 SARS-CoV-2 감염 후 광범위하게 이질적인 체액성 및 세포성 면역Article Published on 2021-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] SARS, 진단, 치료기술, 치료법, [키워드] adaptive Adaptive immunity anti-nucleoprotein antibodies antibodies. antibody Antibody detection cellular immunity cellular response Cellular responses Cohort conducted COVID-19 cross-sectional survey detect detectable Diagnosis Frequency healthy heterogeneity heterogeneous homogeneous humoral humoral and cellular immunity Humoral and cellular responses Humoral response humoral responses implication individual Infection magnitude median median age men Mild Mild disease mild SARS-CoV-2 infection Neutralizing antibodies nine observation Patient persistence recruited reduction SARS-CoV-2 SARS-CoV-2 protein serological test Serological tests South Asian spike study population Surveillance T cell T cell response T cells Vaccination strategies was tested were used with mild disease [DOI] 10.1080/22221751.2021.1999777 PMC 바로가기 [Article Type] Article
Clinical and immunological characteristics in COVID-19 convalescent patientsCOVID-19 회복기 환자의 임상 및 면역학적 특성Article Published on 2021-12-012022-09-11 Journal: European Journal of Clinical Microbiology & Infect [Category] MERS, SARS, 진단, 치료기술, [키워드] acute phase CD4 Cell cellular cellular immunity clinical convalescent COVID-19 patient convalescent COVID-19 patients convalescent patient COVID-19 COVID-19 convalescent patient COVID-19 patient detectable ELISpot testing help humoral humoral and cellular immunity Humoral immunity IFN-γ IFN-γ ELISPOT Immune status immunological characteristics Infection information involved Lymphocytes memory Neutralization assay Neutralizing antibodies non-severe patients Pathogenesis SARS-CoV-2 SARS-COV-2 infection severity significantly higher T cells T lymphocyte the disease vaccine immunity Virus-specific T cells. [DOI] 10.1007/s10096-021-04360-w PMC 바로가기 [Article Type] Article
Cellular immunity predominates over humoral immunity after homologous and heterologous mRNA and vector-based COVID-19 vaccine regimens in solid organ transplant recipients고형 장기 이식 환자에서 동종 및 이종 mRNA 및 벡터 기반 COVID-19 백신 요법 후 체액성 면역보다 세포 면역이 우세합니다.Article Published on 2021-12-012022-09-11 Journal: American journal of transplantation : official jou [Category] SARS, 진단, 치료기술, [키워드] Analysis analyzed antibody CD4 CD4 and CD8 T cells CD4 T cells CD8 T cell CD8 T cells Cell Biology cellular immunity clinical research/practice Control correlated COVID-19 vaccine ELISA first vaccination flow cytometry Heterologous heterologous vaccine homologous homologous or heterologous humoral humoral and cellular immunity Humoral immunity identify IgG Immunity immunocompromised individuals immunogenicity IMPROVE Infection infection and infectious agents - viral infectious agent infectious agents Infectious disease mRNA mRNA-vaccine mRNA-vaccines Neutralization assay Neutralizing activity patients plasmablast plasmablasts priming quantified recipient recipients regimen regimens Responder responders SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody SARS-CoV-2-specific IgG SARS-CoV-2-specific T cell SARS-CoV-2-specific T cells second vaccination significantly higher solid organ solid organ transplant Specific specific antibodies T cell T cell biology T cells vaccination Vaccine vaccine. while [DOI] 10.1111/ajt.16818 PMC 바로가기 [Article Type] Article