High Expression of ACE2 and TMPRSS2 at the Resection Margin Makes Lung Cancer Survivors Susceptible to SARS-CoV-2 With Unfavorable PrognosisOncology Published on 2021-05-212022-10-31 Journal: Frontiers in Oncology [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome Analysis cancer patient Clinical characteristics clinical symptom conducted coronavirus Coronavirus disease 2019 Course COVID-19 diagnosed diagnosed with COVID-19 elevated expression Factor General population Hospitalization Huoshenshan Hospital individual individuals lung cancer margin median time molecular non-cancerous outcome Patient patients with COVID-19 Resection responsible Result retrospective cohort study SARS-CoV-2 Single Cell single-center Spread survivor Survivors susceptibility Symptom symptom onset the disease tissue TMPRSS2 TMPRSS2 level Treatment Wuhan [DOI] 10.3389/fonc.2021.644575 PMC 바로가기 [Article Type] Oncology
Inflammation characteristics and anti-inflammation treatment with tocilizumab of severe/critical COVID-19 patients: A retrospective cohort study중증/심각한 COVID-19 환자의 토실리주맙에 의한 염증 특성 및 항염 치료: 후향적 코호트 연구Research Paper Published on 2021-05-172022-09-12 Journal: International Journal of Biological Sciences [Category] SARS, 진단, [키워드] Admission Anti-inflammation treatment C-reactive protein Characteristics Concentration COVID-19 COVID-19 patient COVID-19 patients Cox proportional-hazards model Critical deaths Deceased demonstrated determine Effectiveness Efficacy enrolled excessive inflammation hospital Hospital mortality Huoshenshan Hospital Inflammation inflammatory factors Inpatient interleukin interleukin-6 laboratory-confirmed Laboratory-confirmed COVID-19 lymphocyte Lymphocytes manifested Mortality neutrophil neutrophil count Patient performed procalcitonin Prognosis progressed propensity score matching recovered patient retrospective cohort study severe and critical patients severe inflammation Tocilizumab treating COVID-19 Treatment Wuhan Wuhan, China [DOI] 10.7150/ijbs.56952 PMC 바로가기 [Article Type] Research Paper
Risk Factors for COVID-19 in Patients with HypertensionResearch Article Published on 2021-05-072022-10-31 Journal: The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien des Maladies Infectieuses et de la Microbiologie Médicale [Category] COVID-19, [키워드] addition Admission Analysis assessments clinical manifestations Cohort Comorbidity Coronary heart disease coronavirus disease COVID-19 COVID-19 patient COVID-19 severity demographic characteristics eligible patient enrolled Factor high risk Huoshenshan Hospital hypertension laboratory data Mortality multivariate logistic regression neutrophil count Patient patients with COVID-19 PSM Pulmonary infection radiological Result risk factor severe COVID-19 severe symptom severity significantly Treatment Volume were used with COVID-19 Wuhan, China [DOI] 10.1155/2021/5515941 PMC 바로가기 [Article Type] Research Article
Implications of cardiac markers in risk-stratification and management for COVID-19 patientsCOVID-19 환자의 위험 계층화 및 관리에서 심장 표지자의 의미Research Published on 2021-04-262022-08-31 Journal: Critical Care [Category] MERS, 바이오마커, [키워드] accompanied Admission age Analysis Biomarker BNP cardiac marker Cardiac markers China CK-MB Cohort collected Coronary artery Coronary artery disease COVID-19 COVID-19 patient COVID-19 patients death Disease diagnosis elevated expression female FIVE had more healthy controls high mortality higher risk hs-TNI Huoshenshan Hospital ICU admission LDH management median age mortality rate Non-COVID-19 Patient patients performed Prognosis prognostic biomarker receiving regression analysis Result retrospective cohort RNA-sequencing SARS-CoV-2 receptor Serum level serum levels significantly higher Single-cell RNA-sequencing supplementary material survival the median Treatment were recorded Wuhan [DOI] 10.1186/s13054-021-03555-z PMC 바로가기 [Article Type] Research
PaO 2 /FiO 2 and IL-6 are risk factors of mortality for intensive care COVID-19 patientsArticle Published on 2021-04-012022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 치료법, [키워드] 95% confidence interval analyzed AUC chest imaging Chi-square coronavirus disease COVID-19 COVID-19 patient dead death in COVID-19 died Huoshenshan Hospital ICU ICUs identify IL-6 independent risk factor independent risk factors intensive care intensive care unit interleukin-6 involved Laboratory logistic regression model Medical research Mortality oxygenation index PaO Patient patients Retrospective analysis Retrospective study risk factor Risk factors student survived Survivors t-test tested the patient variables were used [DOI] 10.1038/s41598-021-86676-3 PMC 바로가기 [Article Type] Article
Myoglobin and C-reactive protein are efficient and reliable early predictors of COVID-19 associated mortality미오글로빈 및 C 반응성 단백질은 COVID-19 관련 사망률의 효율적이고 신뢰할 수 있는 조기 예측 인자입니다Article Published on 2021-03-162022-09-01 Journal: Scientific Reports [Category] SARS, 바이오마커, 임상, 진단, [키워드] age average Biomarkers Blood BNP C-reactive protein cardiac injury collected Comorbidities Comorbidity comprehensive analysis Consensus correlated COVID-19 COVID-19 disease COVID-19 severity CRE CRP D-dimer Deceased demise determine diagnosed with COVID-19 dysfunction elevated full recovery Health care hepatic impairment Huoshenshan Hospital indicated initial symptoms Laboratory lack LDH Medical research Mortality multiple organ failure Myoglobin onset of symptom Organ failure Patient patients predict predictor renal renal damage retrospective cohort study risk factor Risk factors SARS-CoV-2 severely ill patient significantly Signs and symptoms troponin Troponin-I Wuhan [DOI] 10.1038/s41598-021-85426-9 PMC 바로가기 [Article Type] Article
Sex Differences in the Incidence and Risk Factors of Myocardial Injury in COVID-19 Patients: A Retrospective Cohort StudyPhysiology Published on 2021-02-162022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] 95% CI 95% confidence interval adverse events age association BNP both sexes can be used Chronic kidney disease Clinical management Clinical outcome coagulation disorder collected Comorbidity Coronary artery disease correlation COVID-19 COVID-19 patient D-dimer demographic characteristics difference enrolled Factor female Female patients greater Hospitalized Huoshenshan Hospital hypertension identify IMPROVE incidence independent risk factor Inflammation initial symptoms Laboratory test lack leucocyte Logistic regression analysis male mechanisms men myocardial injury novel coronavirus disease Patient Retrospective study risk-factors Sex Sex difference sex differences women [DOI] 10.3389/fphys.2021.632123 PMC 바로가기 [Article Type] Physiology
Potential False-Positive and False-Negative Results for COVID-19 IgG/IgM Antibody Testing After Heat-InactivationMedicine Published on 2021-01-182022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome Affect analyzed antibody Antibody detection Antibody testing caused changes in China condition coronavirus coronavirus disease COVID-19 COVID-19 antibody decrease Effect evaluated false-negative False-positive heat-inactivation Huoshenshan Hospital IgG IgG and IgM IgG and IgM antibody IgM IgM antibody Immunity indicated indirect immunity method MOST negative sample platform positive positive sample Potential produced Result SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgG antibody SARS-CoV-2 IgM SARS-CoV-2-specific IgG significantly increased Spread temperature tested Testing were used Wuhan [DOI] 10.3389/fmed.2020.589080 PMC 바로가기 [Article Type] Medicine
Evolution of COVID-19 in patients with autoimmune rheumatic diseasesResearch Paper Published on 2020-12-152022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, MERS, SARS, [키워드] analyzed ARDS Autoimmune Autoimmune rheumatic diseases caused Characteristics Comorbidity confirmed case Coronavirus disease 2019 Course COVID-19 COVID-19 in patient COVID-19 patient critical cases Critical disease Diseases electronic medical record feature General population higher risk Hospital stay Huoshenshan Hospital ICU admission immune defense immunological immunosuppressive agent laboratory feature less Manifestations Mortality Patient patients proportion reported Retrospective study rheumatic disease rheumatoid arthritis risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus severe cases SLE SPSS suppressed susceptibility systematic lupus erythematosus the cytokine storm [DOI] 10.18632/aging.202193 PMC 바로가기 [Article Type] Research Paper
A nomogramic model based on clinical and laboratory parameters at admission for predicting the survival of COVID-19 patientsCOVID-19 환자의 생존을 예측하기 위해 입원 시 임상 및 실험실 매개변수를 기반으로 하는 노모그램 모델Research Article Published on 2020-11-302022-09-01 Journal: BMC Infectious Diseases [Category] SARS, 진단, [키워드] 95% CI 95% confidence interval Admission age Analysis analyzed AUC Bootstrap method can be used categorical variable categorical variables characteristic CHD chronic heart disease clinician continuous variable continuous variables COVID-19 COVID-19 patient COVID-19 patients D-dimer develop dimer discrimination evaluated exhibited Factor Fisher’s exact test heart disease Hospitalization Huoshenshan Hospital independent risk factor independent risk factors Intervention laboratory data laboratory parameter Lactate lactate dehydrogenase LDH lymphocyte Lymphocytes Measures nomogram outcome Patient patients Pearson Platelet Platelets predict Prediction model Prognosis Protein receiver operating characteristic receiver operating characteristic curve Relative risk Result risk risk factor SARS-CoV-2 Student’s t -test survival variable variables were used Wuhan Wuhan, China [DOI] 10.1186/s12879-020-05614-2 PMC 바로가기 [Article Type] Research Article