Molecular and Cellular Mechanisms of M. tuberculosis and SARS-CoV-2 Infections—Unexpected Similarities of Pathogenesis and What to Expect from Co-InfectionM. tuberculosis와 SARS-CoV-2 감염의 분자 및 세포 기전 - 병인의 예상치 못한 유사성과 동시 감염에서 기대할 수 있는 것Review Published on 2022-02-172022-09-10 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, [키워드] M. tuberculosis infection caused CD4+ T cell cellular Coronavirus infection COVID-19 Critical Diagnosis Disease progression Features Federation hyperinflammation Imbalance Immune suppression immunological Infection Inflammation Isolation knowledge lung tissue injury lymphopenia molecular New coronavirus pathology Personal protective equipment pulmonary tuberculosis Research SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 virus similarities similarity subset T cell Th cell subsets the SARS-CoV-2 virus tissue Treatment Tuberculosis with COVID-19 [DOI] 10.3390/ijms23042235 PMC 바로가기 [Article Type] Review
Sleep Deprivation, Immune Suppression and SARS-CoV-2 InfectionReview Published on 2022-01-142022-10-30 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] addition Defense Deprivation detrimental effect dysregulated environmental factor Evidence Health Host humans immune health Immune suppression immune system immune system suppression Immunity in vivo increased risk Mental outcomes physical promote recent finding reported risk factor SARS-CoV-2 SARS-COV-2 infection Sleep sleep deprivation Sleep disturbance suppression syndrome viruses [DOI] 10.3390/ijerph19020904 PMC 바로가기 [Article Type] Review
Impaired neutralisation of SARS-CoV-2 delta variant in vaccinated patients with B cell chronic lymphocytic leukaemiaB 세포 만성 림프구성 백혈병 백신 접종 환자에서 SARS-CoV-2 델타 변이체 중화 장애Research Published on 2022-01-092022-09-10 Journal: Journal of Hematology & Oncology [Category] 변종, 진단, [키워드] Adenovirus adenovirus-based antibody Antibody Response Antibody responses B cell BTKi therapy CD20 Chronic lymphocytic leukaemia CLL CLL patient CLL patients control group controls COVID COVID-19 vaccination delta variant dominant dual failure functional Gender groups healthy controls healthy donor healthy donors immune protection Immune suppression Immunotherapy Impaired impaired antibody response impaired antibody responses indicate Leukaemia magnitude mRNA neutralisation Patient patient cohort post treatment Post-vaccine Predictive prophylactic antibiotics reduced respond responders responses Result risk SARS-CoV-2 SARS-CoV-2 delta SARS-COV-2 infection sera Seroconversion serum spike-specific antibody response stability supplementary material the SARS-CoV-2 titre titres Treatment vaccination Vaccine vaccine platform variant [DOI] 10.1186/s13045-021-01219-7 PMC 바로가기 [Article Type] Research
Modulation of immunosuppressant drug treatment to improve SARS-CoV-2 vaccine efficacy in miceArticle Published on 2021-12-312023-07-02 Journal: Vaccine [Category] COVID19(2023년), SARS, [키워드] COVID-19 CYC, Cyclophosphamide Immune suppression Immunosuppressant drugs LEF, Leflunomide MM, Mycophenolate mofetil MP, methylprednisolone MTX, methotrexate SARS-CoV-2 Spike protein vaccination [DOI] 10.1016/j.vaccine.2021.12.058 PMC 바로가기 [Article Type] Article
Extensive bilateral diffuse infiltrates and deterioration of lung following infection with severe acute respiratory syndrome coronavirus 2 in a pregnant woman: a case reportCase Report Published on 2021-12-132022-10-30 Journal: Journal of Medical Case Reports [Category] COVID-19, SARS, [키워드] 2019 novel coronavirus acute respiratory distress acute respiratory syndrome Admission Asian Case report caused coronavirus coronavirus disease COVID-19 Critical Deterioration died Extensive higher risk hospital Hypoxemia Immune suppression Infection infiltration lung Maternal death New coronavirus Population Pregnancy pregnant Pregnant woman pregnant women pulmonary fibrosis Research SARS-CoV-2 severe complications severe viral pneumonia syndrome Treatment Viral pneumonia women [DOI] 10.1186/s13256-021-03156-y PMC 바로가기 [Article Type] Case Report
Overlapping but Disparate Inflammatory and Immunosuppressive Responses to SARS-CoV-2 and Bacterial Sepsis: An Immunological Time Course AnalysisObservational Study Published on 2021-12-092022-10-04 Journal: Frontiers in Immunology [Category] SARS, 임상, [키워드] addition Admission Analysis Bacterial sepsis Cell cellular circulating Clinical outcome clinical outcomes Cohort Course COVID patient Critically ill patient dyscrasia elevated ELISPOT enzyme-linked immunospot assay etiology Ex vivo exhibited expression functional healthy control HLA-DR hospitalized patient IFN-gamma immune immune response Immune suppression immunological Immunosuppression incidence Infection Inflammation Inflammatory marker initial less leukocyte MDSC mononuclear cell organ dysfunction patients physiologic derangement plasma biomarker reduced response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 patient secondary bacterial infection Secondary infection secondary infections severe SARS-CoV-2 significantly higher subjects suffered suppressed time TNF-alpha [DOI] 10.3389/fimmu.2021.792448 PMC 바로가기 [Article Type] Observational Study
Perspective of HLA-G Induced Immunosuppression in SARS-CoV-2 InfectionImmunology Published on 2021-12-062022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, SARS, [키워드] acute respiratory syndrome antibody production antiviral immune response Apoptosis B cell caused CD8 Cell Cellular immune response coronavirus COVID-19 COVID-19 disease dendritic cell disease disease severity expression HLA-G Host Human identify immune attack Immune cell immune inhibitory Immune receptor immune responses Immune suppression immunopathological induce induced inhibit inhibitory receptor Interaction KIR knowledge leukocyte Ligand macrophages maturation natural killer NK cell outcomes patients with COVID-19 progression provoke public health receptors regulatory cell SARS-CoV-2 SARS-COV-2 infection T cell the disease transcript upregulated viral clearance viral infections [DOI] 10.3389/fimmu.2021.788769 PMC 바로가기 [Article Type] Immunology
The Spectrum of Antibiotic Prescribing During COVID-19 Pandemic: A Systematic Literature ReviewDisease Published on 2021-12-012022-10-30 Journal: Microbial Drug Resistance [Category] COVID-19, SARS, [키워드] adverse event adverse events adverse outcomes affected age AMR antibiotic Antibiotics Antimicrobial stewardship article articles Bacterial infections children Comorbidities Comorbidity conducted contribute Coverage COVID-19 COVID-19 pandemic criteria English language Evidence Google Scholar identify Immune suppression less literature material NCBI NCBI database Neonate over pathogen Patient prescribing resistance review risk Secondary infection significant increase Spectrum susceptibility systematic review the disease [DOI] 10.1089/mdr.2020.0619 PMC 바로가기 [Article Type] Disease
Adequate immune response after SARS-CoV-2 infection and single dose vaccination despite rapid heart transplantation신속한 심장 이식에도 불구하고 SARS-CoV-2 감염 및 1회 접종 후 적절한 면역 반응Case Reports Published on 2021-12-012022-09-11 Journal: ESC heart failure [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] Adequate antibody assist Assist device BNT booster bridge COVID-19 discharged Effect Heart transplantation immune response Immune suppression male mild SARS-CoV-2 infection mRNA nucleocapsid organ transplantation Orthotopic Orthotopic heart transplantation Patient SARS-CoV-2 SARS-COV-2 infection single dose single vaccination solid organ solid organ transplantation suffered therapy transplantation vaccination ventricular ventricular assist device [DOI] 10.1002/ehf2.13635 PMC 바로가기 [Article Type] Case Reports
Interleukin-10-Mediated Lymphopenia Caused by Acute Infection with Foot-and-Mouth Disease Virus in MiceArticle Published on 2021-11-242022-10-28 Journal: Viruses [Category] COVID-19, [키워드] addition Analysis Apoptosis B cells C57BL/6 CD4 CD8 characterized clinical symptom Clinical symptoms co-inhibitory molecules contribute correlated CTLA-4 CXCL1 disease severity downregulating elevated ENhance expression FMDV foot-and-mouth disease foot-and-mouth disease virus IFN-α/β IL-10 IL-17 IL-18 IL-1β IL-2 IL-6 Immune suppression in vivo Infection interleukin-10 LAG-3 lymphocyte Lymphocyte count lymphopenia mechanism mice Mild NK cell occurred Peripheral blood Prevent reduced serotype serum Signaling Support survival T cell T cells TGF-β Therapeutic approach TIGIT TNF-α Trafficking upregulated [DOI] 10.3390/v13122358 PMC 바로가기 [Article Type] Article