metalloproteinase
[용어속성] Term
MMP-2 and MMP-9 levels in plasma are altered and associated with mortality in COVID-19 patients
Research article
[키워드] ACE2angiotensin-converting enzyme 2
ACEangiotensin-converting enzyme
ACEiangiotensin-converting enzyme inhibitors
Acute kidney injury
affected
age
AKIAcute Kidney Injury
Analysis
Angangiotensin
angiotensin
Angiotensin receptor blockers
Angiotensin-converting enzyme
angiotensin-converting enzyme 2
angiotensin-converting enzyme inhibitors
ARBangiotensin receptor blockers
association
BMI
Clinical outcome
Comorbidity
Control
Coronavirus disease 2019
corticosteroid treatment
COVID-19
COVID-19 group
COVID-19 mortality
COVID-19 patient
COVID-19 patients
COVID-19coronavirus disease 2019
diabetes
Hospital admission
Hospitalization
hypertension
hypertensive COVID-19 patient
ICU
In-hospital death
inhibitors of the renin-angiotensin system
iRAAsinhibitors of the renin-angiotensin system
lung
Manifestations
Matrix Metalloproteinase 2
Matrix Metalloproteinase 9
metalloproteinase
metalloproteinases
MMP-2Matrix Metalloproteinase 2
MMP-9Matrix Metalloproteinase 9
MMPsmetalloproteinases
Mortality
not affected
obesity
pathophysiologic
Patient
patients with COVID-19
plasma
predicted
predictor
prognostic
RASRenin-angiotensin system
renin-angiotensin system
respiratory
risk
SAPS3Simplified Acute Physiology Score III
SARS-CoV-2severe acute respiratory syndrome coronavirus 2
sequential organ failure assessment score
severe acute respiratory syndrome coronavirus 2
severe COVID-19
Sex
Simplified Acute Physiology Score III
SOFA score
SOFAsequential organ failure assessment score
study group
survival
Symptom
treated
were measured
[DOI] 10.1016/j.biopha.2021.112067 [Article Type] Research article
[DOI] 10.1016/j.biopha.2021.112067 [Article Type] Research article
Matrix metalloproteinases are involved in the development of neurological complications in patients with Coronavirus disease 2019
Article
[키워드] Adhesion Molecule
caused
CCL2
CCL3
CCL4
CCL7
cerebrospinal fluid
chemokine
chemokines
Coronavirus disease 2019
COVID-19
COVID-19 patient
CSF
CX3CL1
CXCL8
cytokine
E-selectin
ENhance
evaluated
expression
Frequency
help
ICAM-1
IL-1β
IL-6
Increased
infiltration
inflammatory cell
Inflammatory cytokine
Inflammatory cytokines
involved
Level
matrix
matrix metalloproteinases
metalloproteinase
monocyte
Monocytes
neurological
Neurological complication
Neurological symptom
Patient
promote
recruitment
Result
resulting
secreted
serum
significantly increased
syndrome
the patient
TNF-α
treated
VCAM-1
viral infections
[DOI] 10.1016/j.intimp.2021.108076 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.intimp.2021.108076 PMC 바로가기 [Article Type] Article
Active matrix metalloproteinase-8 (aMMP-8) point-of-care test (POCT) in the COVID-19 pandemic
COVID-19 전염병에서 활성 매트릭스 금속단백분해효소-8(aMMP-8) 현장 진료 검사(POCT)
Review
[키워드] Activation
Active matrix
addressed
Affect
Analysis
Area
Biomarker
Biomarkers
Cancer
catalytic activity
chlorhexidine
coronavirus disease
Coronavirus disease 2019
correlation
correlations
Course
COVID-19
COVID-19 pandemic
degranulation
detect
diabetes
diagnostics
disease
Diseases
doxycycline
expert
expression
Factor
help
Host
immunoassay
independent
inhibit
lateral flow
matrix
matrix metalloproteinase
Matrix metalloproteinase 8
metalloproteinase
microbial
MONITOR
mouth rinse
neutrophil
noninvasive
oral fluids
peri
peri-implantitis
Periodontitis
POCT
point-of-care
potential risk
prediabetes
predict
Quantitative
Radiotherapy
Saliva
Side-effect
Side-effects
tissue
Treatment
[DOI] 10.1080/14789450.2021.1976151 PMC 바로가기 [Article Type] Review
[DOI] 10.1080/14789450.2021.1976151 PMC 바로가기 [Article Type] Review
Low ADAMTS13 Activity Correlates with Increased Mortality in COVID-19 Patients
Original Article
[키워드] Activation
activity
ADAMTS13
Admission
Antigen
association
Biomarker
Biomarkers
cause
Coagulation
Coagulopathy
conducted
coronavirus disease
COVID-19
COVID-19 patient
D-dimer
died
discharged
disease severity
distribution
Efficacy
elevated
elevated lactate dehydrogenase
endothelial
greater
Hemolysis
hospitalized COVID-19 patient
hospitalized patients
Increased
less
metalloproteinase
Mortality
motif
nonsurvivors
organ damage
Patient
Presence
Randomly
Retrospective study
schistocytes
selected
significantly
significantly increased
significantly lower
subset
survived
survivor
Treatment
von Willebrand factor
vWF
[DOI] 10.1055/s-0041-1723784 PMC 바로가기 [Article Type] Original Article
[DOI] 10.1055/s-0041-1723784 PMC 바로가기 [Article Type] Original Article
Matrix metalloproteinase 3 as a valuable marker for patients with COVID-19
COVID-19 환자를 위한 중요한 표지자로서의 기질 금속단백분해효소 3
Article
[키워드] analyzed
biochemical
center
Chinese
collected
Concentration
concentrations
Control
coronavirus disease
Coronavirus disease 2019
Coronavirus pneumonia
COVID-19
COVID-19 patient
Cytokines
detect
detection
healthy individual
IL-1β
IL-6
Inflammation
Inpatients
interleukin
marker
matrix
matrix metalloproteinase
Medicine
metalloproteinase
MMP3
MMP3 concentrations
Non-COVID-19
normality
Novel coronavirus
patients with COVID-19
Pneumonia
positive correlation
prevention
Prevention and control
proinflammatory cytokines
sera
serum
Serum level
serum levels
Severity of disease
situation
SPSS
statistically significant
Therapeutic approach
therapeutic approaches
two group
two groups
university
Wilcoxon rank sum
Wilcoxon rank sum test
[DOI] 10.1002/jmv.26235 PMC 바로가기 [Article Type] Article
[DOI] 10.1002/jmv.26235 PMC 바로가기 [Article Type] Article
Sex differences in COVID-19: candidate pathways, genetics of ACE2, and sex hormones
COVID-19의 성별 차이: 후보 경로, ACE2의 유전학 및 성 호르몬
Review
[키워드] ACE2
Activation
ADAM17
added
angiotensin
Angiotensin-converting enzyme
angiotensin-converting enzyme 2
antiviral response
Biological
canonical
cardiovascular disease
caused
contribute
coronavirus
COVID-19
COVID-19 pandemic
Critical
dependent on
disease
disease pathogenesis
disease severity
disintegrin
epidemiological data
exacerbate
female
females
Gender
genetics
Health
highlight
increase in
increasingly
innate immune response
innate immune system
involved
leads
Loss
male
mechanism
membrane
metalloproteinase
Mortality
outcomes
Pathways
plasma
positive
positive feedback
potential mechanism
potential mechanisms
protective mechanism
proteolytic cleavage
RAS
receptor
Renin
renin-angiotensin system
SARS epidemic
SARS-CoV-2
SARS-CoV-2 coronavirus
SARS-COV-2 infection
severe disease
Sex
sex differences
sex hormone
Sex hormones
susceptibility
the SARS-CoV-2
Viral
viral entry
worsened
[DOI] 10.1152/ajpheart.00755.2020 PMC 바로가기 [Article Type] Review
[DOI] 10.1152/ajpheart.00755.2020 PMC 바로가기 [Article Type] Review
Insights Into Immunothrombosis: The Interplay Among Neutrophil Extracellular Trap, von Willebrand Factor, and ADAMTS13
Immunology
[키워드] activated neutrophil
Activation
acute ischemic stroke
ADAMTS13
addition
aggregation
AIS
Blood
Cell
Characteristics
complex
contribute
COVID-19
endothelial
endothelial damage
events
Evidence
Factor
immunothrombosis
Increasing
indicate
induce
Inflammation
insight
Interaction
metalloproteinase
Mortality
motifs
NET
NETs
Neutrophil extracellular trap
Neutrophil extracellular traps
occur
predict
reduction
regulated
released
secretion
stroke
targeting
therapeutic strategy
thrombosis
thrombotic
thrombotic microangiopathy
vasculature
Venous thrombosis
von Willebrand factor
vWF
[DOI] 10.3389/fimmu.2020.610696 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2020.610696 PMC 바로가기 [Article Type] Immunology
COVID‐19 patients in intensive care develop predominantly oliguric acute kidney injury
중환자실의 코로나19 환자는 주로 핍뇨성 급성 신장 손상을 일으키고 있습니다.
Observational Study
[키워드] Acute kidney injury
Admission
AKI
albumin
albuminuria
analysed
Biomarker
Biomarkers
Characteristics
Chronic kidney disease
COVID‐19
COVID‐19 patient
COVID‐19
creatinine
criteria
develop
evaluated
filtration rate
Final
functional
glomerular filtration rate
ICU
identify
incidence
initial
intensive care
KDIGO
Kidney disease
Kidney injury
lead
majority
metalloproteinase
microalbuminuria
molecule
Mortality
Most patient
Most patients
neutrophil
observational study
occurred
oliguria
Patient
patients
plasma
predict
prospective observational study
reduced
renal replacement therapy
renal tissue
replacement therapy
risk
stage 2
syndrome
therapy
tissue damage
Tissue Inhibitor
urinary
Urine
Virus Disease
Volume
[DOI] 10.1111/aas.13746 PMC 바로가기 [Article Type] Observational Study
[DOI] 10.1111/aas.13746 PMC 바로가기 [Article Type] Observational Study
ACE2/ADAM17/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19
Immunology
[키워드] ACE2
Activation
ADAM17
angiotensin-converting enzyme 2
cardiovascular
caused
Clinical outcome
coagulation cascade
Comorbidities
Comorbidity
Course
COVID-19
COVID-19 pathophysiology
death
Deleterious
diabete
disease
domain
exacerbated
explain
expression
Factor
Genetic
host protein
hypertension
IL-6R
infection rate
inflammatory immune response
Interaction
Lung disease
male
mechanism
men and women
metalloproteinase
Occurrence
outcome
pathophysiological
patients
RAS
SARS-CoV-2
secretion
the disease
TMPRSS2
TNF-α
transmembrane serine protease
[DOI] 10.3389/fimmu.2020.576745 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2020.576745 PMC 바로가기 [Article Type] Immunology