Elevated IL-18 predicts poor prognosis in critically ill COVID-19 patients at a Brazilian hospital in 2020-21Article Published on 2022-11-012022-11-15 Journal: Future Microbiology [Category] SARS, 바이오마커, [키워드] analyzed association Biomarker Brazil clinical outcomes contribute COVID-19 COVID-19 patient Critically ill Critically ill patient cross-sectional cytokine Deceased dysregulated evaluated exhibited hospital IL-18 immune immune response Inflammation Inflammatory response Innate immunity innate immunity. intensive care laboratory data marker Older Patient patients with COVID-19 Platelet poor prognosis predict quantified significantly higher sociodemographic data with COVID-19 [DOI] 10.2217/fmb-2022-0057 PMC 바로가기
A “Post-mortem” of COVID-19-Asscoiated Stroke: a Case-control StudyResearch article Published on 2022-11-012022-10-05 Journal: Journal of stroke and cerebrovascular diseases : t [Category] SARS, 진단, [키워드] aetiology carried Case-control case-control study controls COVID-19 COVID-19 negative COVID-19-associated stroke death help higher risk Hopefully Hospitalization Italy Large vessel occlusion management material objective pandemic Patient patients with COVID-19 Result retrospective SARS-CoV-2 stroke worsening [DOI] 10.1016/j.jstrokecerebrovasdis.2022.106716 [Article Type] Research article
Association between disease-modifying therapies and adverse clinical outcomes in multiple sclerosis patients with COVID-19 infectionResearch article Published on 2022-11-012022-10-05 Journal: Multiple sclerosis and related disorders [Category] 진단, [키워드] adjusted Admission admitted to ICU association Clinical outcome COVID-19 cross-sectional diagnosis of COVID-19 Disease-modifying therapies Electronic health record General population health systems Healthcare provider Hospital admission Hospitalization Hospitalized ICU immunomodulatory immunosuppressive in-hospital mortality increased risk Infection Iran Mortality mortality risk multiple sclerosis outcome Patient patients with COVID-19 PCR Result risk risk factor Severe COVID-19 Infection severity therapy vaccinated against COVID-19 were recorded [DOI] 10.1016/j.msard.2022.104067 [Article Type] Research article
Spike-specific T-cell responses in patients with COVID-19 successfully treated with neutralizing monoclonal antibodies against SARS-CoV-2Article Published on 2022-11-012022-11-15 Journal: International Journal of Infectious Diseases [Category] SARS, 진단, [키워드] Administered analyzed CD4 CD8 cellular response Clinical outcome COVID-19 demonstrated effective evaluate Evolution flow cytometric group healthy controls immune memory Immunity Impact impair IMPROVE increases in individuals Infection initial investigated marker median memory memory T-cell response monoclonal antibodies monoclonal antibody neutralizing monoclonal antibody Patient patients patients treated patients with COVID-19 receiving SARS-CoV-2 significant increases in SOT spike statistically significant statistically significant difference T-cell Response T-cell response. treated Treatment Viral diseases were measured [DOI] 10.1016/j.ijid.2022.09.016 PMC 바로가기
Viral load may impact the diagnostic performance of nasal swabs in nucleic acid amplification test and quantitative antigen test for SARS-CoV-2 detectionArticle Published on 2022-11-012022-11-15 Journal: Journal of infection and chemotherapy : official j [Category] SARS, 치료기술, [키워드] amplification Antigen automated collected cycle threshold detect diagnostic early stage evaluated healthcare Measures NAAT nasal swab nasal swabs Nasopharyngeal swab nasopharyngeal swabs negative correlation nine NPs nucleic acid amplification nucleic acid amplification test patients with COVID-19 positive Quantitative Quantitative SARS-CoV-2 antigen test Respiratory Coronavirus SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 detection significantly significantly higher significantly lower symptom onset tested Viral load Viral load. were used [DOI] 10.1016/j.jiac.2022.07.023 PMC 바로가기
Comparison of COVID-19 pneumonia during the SARS-CoV-2 Omicron wave and the previous non-Omicron wave in a single facilityArticle Published on 2022-11-012022-11-16 Journal: Respiratory investigation [Category] SARS, 변종, [키워드] acute respiratory syndrome addition caused characteristic Characteristics Chest CT Cluster-like ground-glass opacities Computed tomography consolidation coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 described disease distribution enrolled evaluated GGO GGOs ground-glass opacity groups hospital omicron Omicron variant other variants patients with COVID-19 Pneumonia pneumonia. predominant Prevalence random replicate significantly lower the SARS-CoV-2 variant variants [DOI] 10.1016/j.resinv.2022.08.001 PMC 바로가기
The effect of Nutrition Bio-shield superfood (NBS) on disease severity and laboratory biomarkers in patients with COVID-19: A randomized clinical trialArticle Published on 2022-11-012022-11-15 Journal: Microbial pathogenesis [Category] SARS, 바이오마커, [키워드] ALP assigned baseline body temperature can be used clinical clinical trial Clinical trial study control group COVID-19 COVID-19 disease COVID-19 disease severity CPK CRP determine dimer disease severity Effect effective ELISA kit ESR IL-6 immune system IMPROVE Intervention intervention group Iran laboratory biomarker laboratory biomarkers laboratory parameter LDH lymphocyte Lymphocyte count nutrition Nutrition bio-shield superfood. oxygen saturation Patient patients with COVID-19 performed Placebo Randomized randomized clinical trial receiving Result Serum level serum sample SGOT SGPT significant decrease significant increase single-blind Superfood Tehran tested the mean TNF-α Treatment Trial two group Two-arm variable was performed WBC [DOI] 10.1016/j.micpath.2022.105792 PMC 바로가기
Fungal colonization and infections in patients with COVID-19 in intensive care units: A real-life experience at a tertiary-care hospitalResearch article Published on 2022-11-012022-10-05 Journal: Respiratory medicine and research [Category] 진단, [키워드] age antifungal therapy Antifungal treatment Candida albican Candida albicans Computed tomography COVID-19 COVID-19 diagnosis COVID-19-associated pulmonary aspergillosis cross-contamination diagnostic evaluate exhibited Fatality rate fungal Fungal colonization Fungal infection highlight hospital ICU ICUs Infection intensive care intensive care unit Invasive mechanical ventilation laboratory data management mechanical ventilation medical records men outcome pandemic Patient patients patients with COVID-19 performed problem Result risk Risk factors the patient Thorax women [DOI] 10.1016/j.resmer.2022.100937 [Article Type] Research article
Does timing matter on tocilizumab administration? Clinical, analytical and radiological outcomes in COVID-19Article Published on 2022-11-012022-11-15 Journal: European Journal of Hospital Pharmacy [Category] SARS, 진단, [키워드] 30-Day mortality Administered administration adverse event adverse events analysed Biomarker C-reactive protein clinical Clinical improvement cohorts of patient comparable complementary Complementary therapies coronavirus disease COVID-19 Critical Critical care decrease Efficacy epidemiologically group hospitalised Hypothesis inflammatory parameters knowledge lactate dehydrogenase medication Mortality onset of symptom outcome Patient patients with COVID-19 pharmacological treatment Pneumonia Primary outcome pulmonary medicine Quotient radiological radiological improvement Radiology. randomised controlled trial reductions in SaO_{2} secondary Severe COVID-19 pneumonia statistically significant difference subgroup subgroups the timing therapy Tocilizumab tocilizumab administration two group were recorded while [DOI] 10.1136/ejhpharm-2020-002669 PMC 바로가기
A comparative analysis of the outcomes of patients with influenza or COVID-19 in a tertiary hospital in BelgiumResearch article Published on 2022-11-012022-10-05 Journal: Journal of infection and chemotherapy : official j [Category] 진단, 치료기술, [키워드] Admission Analysis bacterial superinfection Belgium cardiovascular complication cohort study COVID-19 COVID-19 pandemic COVID-19 patient died difference ECMO Health hospital hospitalized patient ICU ICU admission in-hospital mortality increased risk Influenza influenza infection intensive care Intubation rates morbidity and mortality Mortality outcome Outcome comparison Patient patients with COVID-19 patients with influenza Propensity score matched analysis readmission required Result retrospective Seasonal influenza secondary severity single-center with COVID-19 [DOI] 10.1016/j.jiac.2022.07.012 [Article Type] Research article