Association between history of HBV vaccine response and anti-SARS-CoV-2 spike antibody response to the BioNTech/Pfizer’s BNT162b2 mRNA SARS-CoV-2 vaccine among healthcare workers in Japan: A prospective observational study일본 의료 종사자들 사이에서 BioNTech/Pfizer의 BNT162b2 mRNA SARS-CoV-2 백신에 대한 HBV 백신 반응과 항 SARS-CoV-2 스파이크 항체 반응의 연관성: 전향적 관찰 연구Observational Study Published on 2022-05-162022-09-12 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 95% confidence interval age Analysis anti-SARS-CoV-2 Antibody Response Antibody titer baseline BNT162b2 BNT162b2 mRNA BNT162b2 vaccine booster dose calculated Comorbidity comparable confidence interval COVID-19 pandemic defined dose doses faster follow-up study HBV healthcare healthcare worker immune response Inadequate long term non-responder participant Patient pharmaceutical prospective observational study protective immunity Protein recruited Responder responses against risk Roche S-protein SARS-CoV-2 SARS-CoV-2 vaccine second dose seroconvert seroconverted single dose tested university vaccination Vaccine vaccine response [DOI] 10.1371/journal.pone.0268529 PMC 바로가기 [Article Type] Observational Study
Antiviral Efficacy of Molnupiravir for COVID-19 Treatment코로나19 치료를 위한 몰누피라비르의 항바이러스 효능Article Published on 2022-04-062022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] 95% CI active against Administered Antiviral antiviral drug antiviral drugs antiviral efficacy antiviral efficacy. coronavirus COVID-19 COVID-19 pandemic exacerbated expected global pandemic Government granular growth infected cell infected cells infectiousness inhibit Intervention mathematical molnupiravir per day pharmaceutical Pharmaceutical interventions public health reduce Replication risk SARS-CoV-2 SARS-CoV-2 variants Seven treated Viral load virus [DOI] 10.3390/v14040763 PMC 바로가기 [Article Type] Article
A phase 1/2 randomised placebo-controlled study of the COVID-19 vaccine mRNA-1273 in healthy Japanese adults: An interim report건강한 일본 성인을 대상으로 한 코로나19 백신 mRNA-1273의 1/2상 무작위 위약 대조 연구: 중간 보고서Clinical Trial Published on 2022-03-182022-09-12 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 95% CI 95% confidence interval acute respiratory syndrome Administered adverse event AEs age AMED anti-SARS-CoV-2 immune response antibody ARMS baseline company conducted coronavirus COVID-19 COVID-19 vaccine mRNA-1273 demonstrated development dose ENCODE enrolled fatigue geometric healthy immune response immunogenicity Injection-site pain Interim report Intramuscular injection Japan Japanese Limited mRNA vaccine mRNA-1273 myalgia NAb neutralising antibody occurred outcome participant Participants pharmaceutical Placebo placebo-controlled study placebo-controlled trial randomised receive reported Safety safety profile SARS-CoV-2 SARS-COV-2 infection secondary outcome Spike protein stratified Takeda vaccination Vaccine [DOI] 10.1016/j.vaccine.2022.02.030 PMC 바로가기 [Article Type] Clinical Trial
Building the Momentum for A Stronger Pharmaceutical System in Africa아프리카에서 더 강력한 제약 시스템의 추진력 구축Article Published on 2022-03-112022-08-31 Journal: International Journal of Environmental Research an [Category] MERS, 치료제, [키워드] affected Africa Algeria building complex continent country Coverage COVID-19 COVID-19 pandemic Critical eight had more had no Health Kenya labelling Local Medicines momentum Morocco National Nigeria pharmaceutical pharmaceutical system strengthening. reflect Regulatory scaled solvent South Africa Structure System Vaccine Vaccines [DOI] 10.3390/ijerph19063313 PMC 바로가기 [Article Type] Article
Knowledge, attitude, and perception of public about participation in COVID-19 clinical trials: A study from Egypt and Saudi ArabiaResearch article Published on 2022-03-012022-10-05 Journal: Saudi Pharmaceutical Journal : SPJ [Category] 임상, [키워드] adopted Affect approved clinical trial clinical trials conducted country COVID-19 COVID-19 treatments cross-sectional determinant education evaluate gold standard Healthcare professional help IMPROVE Increased knowledge media MENA Middle East moderate MOST North Older participant Patient Patient participation Perception pharmaceutical Potential treatment Prevent proportion public opinion recruitment registry data Result Saudi Arabia treat Treatment Trial [DOI] 10.1016/j.jsps.2022.01.008 [Article Type] Research article
Impact of COVID-19 Pandemic on the Use of Antidepressant and Antianxiety Pharmaceuticals as Well as Sick Leave in PolandCovid-19 Pandemic이 항우울제 및 항발성 제약의 사용 및 폴란드의 병가의 영향Article Published on 2022-02-142022-08-31 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), MERS, SARS, 치료제, [키워드] absence analyzed antianxiety antidepressant antidepressants Anxiety caused Clinical practice Consumption COVID-19 COVID-19 pandemic Depression Diagnosis Impact impacted Interrupted Measures medication mental condition mental health pandemic Patient pharmaceutical Pharmaceuticals physician Poland Psychiatric psychiatric patients reaction Research Sery sick leave significantly strain Stress time Treatment well Workplace [DOI] 10.3390/ijerph19042135 PMC 바로가기 [Article Type] Article
Biomedical Potential of the Neglected Molluscivorous and Vermivorous Conus SpeciesReview Published on 2022-01-272022-10-30 Journal: Marine Drugs [Category] Coronavirus, SARS, [키워드] Conus Andaman Islands biomedical compounds Biomedical research candidate categories coast Conotoxin Conus correlation demonstrated distribution map Drug discovery Evolution exhibited explicit feeding habit functional highlight highlighting hotspot include malaria therapy multi Neglected Neogene observation Perspective pharmaceutical Phylogenetic relationship Phylogenetic tree Potential promote receive Reclaiming Research resource SARS-CoV-2 Specy urgency Virological warm worm worms [DOI] 10.3390/md20020105 PMC 바로가기 [Article Type] Review
Exploring the Pharmaceutical Care of Pharmacists in China During COVID-19—A National Multicenter Qualitative StudyPublic Health Published on 2022-01-272022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] applied China Chinese conducted coronavirus COVID-19 COVID-19 epidemic COVID-19 pandemic described drugs emergency response FIVE hospital hospitals improvement management multicenter narcotic National pandemic pharmaceutical Pharmaceutical care Pharmacist pharmacists Psychotropic drugs Purposive sampling Qualitative qualitative study Result single-center study Treatment vital roles [DOI] 10.3389/fpubh.2021.797070 PMC 바로가기 [Article Type] Public Health
Association between pharmaceutical modulation of oestrogen in postmenopausal women in Sweden and death due to COVID-19: a cohort study스웨덴 폐경 후 여성에서 에스트로겐의 제약 조절과 COVID-19로 인한 사망의 연관성 : 코호트 연구Epidemiology Published on 2022-01-142022-08-31 Journal: BMJ Open [Category] COVID19(2023년), Fulltext, MERS, SARS, 치료제, [키워드] 95% CI absolute risk adjusted Adjustment age annual income augmentation board Board of Health Breast cancer Charlson Comorbidity Index Cohort cohort study Comorbidity confounder control group COVID-19 death decrease defined diagnosed diagnosed with COVID-19 Endocrine Endocrine Therapy Epidemiology groups highest hormone replacement therapy individual Intervention level of education modulation objective outcome measure participant pharmaceutical positive postmenopausal Primary outcome Public Public Health Agency randomised receiving registries remained replacement therapy Result retrospective risk risk of death sex steroids & HRT significantly Statistics Swedish tested therapy Trial variables Welfare women [DOI] 10.1136/bmjopen-2021-053032 PMC 바로가기 [Article Type] Epidemiology
Machine Learning and Artificial Intelligence in Pharmaceutical Research and Development: a Review제약 연구 및 개발의 기계 학습 및 인공 지능: 검토Review Published on 2022-01-042022-09-11 Journal: The AAPS Journal [Category] 비임상, [키워드] accelerate Analysis anticipated approach artificial artificial intelligence automated breath clinical clinical trial Clinical trial design clinical trials COVID-19 pandemic Critical driven by drug Drug development Drug discovery Efficiency expected help Hope increase in Inference inferences intelligence machine machine learning manuscript market occur offer over Patient pharmaceutical pharmaceutical industry positive precision medicine Predictive Predictive modeling Probability of success recognize Research research and development review Risk-based monitoring. Trial utilization Volume [DOI] 10.1208/s12248-021-00644-3 PMC 바로가기 [Article Type] Review