Does metformin affect outcomes in COVID-19 patients with new or pre-existing diabetes mellitus? A systematic review and meta-analysisReview Published on 2022-06-012022-10-04 Journal: British Journal of Clinical Pharmacology [Category] 신약개발, [키워드] adjusted Affect affected approach biguanides carried certainty cohort study coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic COVID-19 patient database diabete Diabetes Mellitus Effect Evidence exhibiting global public health glycaemic control highlight immune responses IMPROVE lower mortality Meta-analysis metformin Mortality Odds ratio outcome outcomes Patient patients with COVID-19 patients with diabete Poor Primary outcome Quantitative random-effect Randomised trial recent Registered reported risk of bia robust SARS-CoV-2 searched shown significantly systematic review Treatment type 2 diabetes type 2 diabetes. weakened Web of Science [DOI] 10.1111/bcp.15258 PMC 바로가기 [Article Type] Review
The Presence of Either Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients from a Multinational Observational Study: Data from Euroguidelines in Central and Eastern Europe Network GroupObservational Study Published on 2022-05-052022-10-05 Journal: Viruses [Category] COVID19(2023년), SARS, 임상, [키워드] admitted to ICU analysis Antiretroviral therapy ARDS association Atypical CD4 change changes chest X-ray Co-infection Comorbidity Computed tomography country Course COVID-19 death diagnosed died differential diagnose ECEE eCRF Europe European Factor group HBV HCV healthcare HIV HIV patient Hospitalized ICU admission identify infections lung multivariate model network Observational data outcome outcomes Oxygen therapy Patient patients performed Pneumonia pneumonia. Poor predicted Presence radiological Regression model required RT-PCR tests SARS-CoV-2 significantly submitted symptomatic symptomatic SARS-CoV-2 infection Treatment Typical were used [DOI] 10.3390/v14050972 PMC 바로가기 [Article Type] Observational Study
Poor evidence for host-dependent regular RNA editing in the transcriptome of SARS-CoV-2SARS-CoV-2의 전사체에서 숙주 의존적 정규 RNA 편집에 대한 불충분한 증거Article Published on 2022-05-012022-09-11 Journal: Journal of applied genetics [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Evidence Poor RNA SARS-CoV-2 Transcriptome [DOI] 10.1007/s13353-022-00687-y PMC 바로가기 [Article Type] Article
B Cell Aplasia Is the Most Powerful Predictive Marker for Poor Humoral Response after BNT162b2 mRNA SARS-CoV-2 Vaccination in Recipients of Allogeneic Hematopoietic Stem Cell TransplantationB 세포 무형성은 동종 조혈모세포 이식 환자에서 BNT162b2 mRNA SARS-CoV-2 백신 접종 후 불량한 체액 반응에 대한 가장 강력한 예측 마커입니다Article Published on 2022-05-012022-09-11 Journal: Transplantation and cellular therapy [Category] COVID19(2023년), MERS, SARS, 바이오마커, 치료기술, [키워드] 95% confidence interval absence administration age allo-HSCT Allogeneic allogeneic hematopoietic stem cell transplantation Analysis analyzed anti-SARS-CoV-2 vaccination Antibody Response Antibody responses aplasia B cell B cells B-cell BNT162b2 BNT162b2 mRNA CD4 CD8 characteristic close monitoring Cohort COVID-19 Donor Efficacy entire cohort evaluate evaluated Factor hematopoietic Hematopoietic stem cell highest HSCT humoral Humoral response immune response Immune status Immunosuppressed immunosuppressed patients injection lymphocyte Lymphocyte count lymphopenia median MOST mRNA natural killer cell Natural killer cells Odds ratio of BNT162b2 Patient Poor predict provided recipient recipients reported responders response response rate SARS-CoV-2 SARS-CoV-2 mRNA SARS-CoV-2 vaccination SARS-CoV-2 vaccine Specific STEM stem cell Stem cell transplantation T cell T cells the antibody response transplantation Treatment Univariate analysis vaccine. were assessed [DOI] 10.1016/j.jtct.2022.02.018 PMC 바로가기 [Article Type] Article
Elevated CD21 low B Cell Frequency Is a Marker of Poor Immunity to Pfizer-BioNTech BNT162b2 mRNA Vaccine Against SARS-CoV-2 in Patients with Common Variable Immunodeficiency증가된 CD21 낮은 B 세포 빈도는 공통 가변성 면역결핍증 환자에서 SARS-CoV-2에 대한 화이자-바이오엔텍 BNT162b2 mRNA 백신에 대한 면역 저하의 지표입니다Clinical Trial Published on 2022-05-012022-09-12 Journal: Journal of Clinical Immunology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] affected Against analyzed antibody B-cell baseline BNT162b2 mRNA BNT162b2 mRNA vaccination BNT162b2 mRNA vaccine CD21 CD21low B-cells CD4 cell count central memory clinical trial cohort of patient common correlated COVID-19 COVID-19 vaccination CVID demonstrated dose Frequency healthy control Humoral immunity IFN-γ IgG immune response immunocompromised individuals immunodeficiency Limited median titer memory B-cell Open-label Patient patients patients with CVID Pfizer-BioNTech Pfizer-BioNTech BNT162b2 mRNA vaccine Poor positive proportion reached reduced response SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike-specific SARS-CoV-2. second dose selected seroconverted seronegative significantly single-center T cell response T-cell the vaccine threshold vaccine responses variable were assessed [DOI] 10.1007/s10875-022-01244-2 PMC 바로가기 [Article Type] Clinical Trial
Poor Respiratory Health Following Relapsing SARS-CoV-2 Infection in Children with Cystic Fibrosis낭포성 섬유증이 있는 어린이의 SARS-CoV-2 감염 재발 후 불량한 호흡기 건강Article Published on 2022-04-012022-09-11 Journal: Indian journal of pediatrics [Category] COVID19(2023년), SARS, 치료기술, [키워드] allergic bronchopulmonary allergic bronchopulmonary aspergillosis Asymptomatic bronchopulmonary aspergillosis children chronic lung disease clearance clearance of SARS-CoV-2 COVID-19 COVID-19 severity Cystic cystic fibrosis described develop diabete diabetes diagnosed fibrosis High-flow nasal oxygen intensive care lung Lung disease mild infection morbidity Noninvasive ventilation oxygen Pneumonia Poor Poor lung health Prolonged prolonged viral shedding recurrence respiratory Respiratory failure respiratory infection SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2. severe COVID-19 severe disease Support symptomatic disease [DOI] 10.1007/s12098-021-04057-0 PMC 바로가기 [Article Type] Article
Poor Antibody Response After Two Doses of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine in Transplant Recipients이식 수혜자에서 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 백신 2회 접종 후 항체 반응 불량Article Published on 2022-03-232022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] MERS, SARS, 진단, [키워드] Anti-spike anti-spike antibodies anti-spike antibody response BNT162b2 vaccine coronavirus 2 coronavirus disease COVID-19 COVID-19 disease doses humoral humoral response. Poor recipient reported respiratory response SARS-CoV-2 SARS-CoV-2 vaccination second dose Serious Adverse Event severe COVID-19 solid organ transplant SOT SOT recipients the vaccine Transplant were recorded [DOI] 10.1093/cid/ciab580 PMC 바로가기 [Article Type] Article
Poor oral health may prolong COVID-19 illnessLetter to the Editor Published on 2022-03-072022-10-30 Journal: Journal of Translational Medicine [Category] Coronavirus, MERS, SARS, [키워드] COVID-19 illness Health Poor [DOI] 10.1186/s12967-022-03310-0 PMC 바로가기 [Article Type] Letter to the Editor
Prevalence and Risk Factors of Poor Sleep Quality in Collegiate Athletes during COVID-19 Pandemic: A Cross-Sectional StudyArticle Published on 2022-03-062022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] Anxiety athlete change changed Characteristics circadian rhythms correlated COVID-19 COVID-19 pandemic cross-sectional evaluated exacerbated exercise Factor female female gender FIVE Gender index lack lifestyle habits Linear regression median mental health nocturnal normality pandemic performed physical activity habits Poor Prevalence prevalent Quality questionnaire Result significantly Sleep sleep deprivation sleep disrupters Sleep Hygiene sleep quality student athletes subject training Volume was performed [DOI] 10.3390/ijerph19053098 PMC 바로가기 [Article Type] Article
Association of Poor Mental-Health Days With COVID-19 Infection Rates in the U.S.Research article Published on 2022-03-012022-10-05 Journal: American journal of preventive medicine [Category] SARS, 바이오마커, [키워드] adjusted association average Bayesian change Community conducted confirmed case covariates COVID-19 COVID-19 infection COVID-19 infections cumulative Day Depression Evidence Factor General population IMPROVE Limited mental health mental health problems Poor poor mental health Prevalence problem Rate reported Result significantly Stress subsequent System was tested with COVID-19 [DOI] 10.1016/j.amepre.2021.08.032 [Article Type] Research article