Relationship between Hepatitis B virus infection and platelet production and dysfunctionReview Published on 2022-02-172023-06-11 Journal: Platelets [Category] B형 간염, [키워드] Hepatitis B virus megakaryocyte Platelet regeneration thrombocytopenia [DOI] 10.1080/09537104.2021.2002836 [Article Type] Review
Matrix metalloproteinases (MMP) 3 and 9 as biomarkers of severity in COVID-19 patientsCOVID-19 환자의 중증도 바이오마커로서의 기질 금속단백분해효소(MMP) 3 및 9Clinical Trial Published on 2022-01-242022-09-10 Journal: Scientific Reports [Category] 바이오마커, 임상, 진단, 치료법, [키워드] benefit Biomarker Biomarkers circulating neutrophil circulating neutrophils clinical heterogeneity contribute controls coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 severity disease severity Diseases Health Organization help Hospital admission Hospitalization hospitalized patient immunology inflammatory process interleukin-6 lung damage Lung inflammation matrix matrix metalloproteinases Medical research metalloproteinase MMP3 MMP9 molecular basis monocyte Monocytes myeloperoxidase Neutrophils no correlation occur pathogenic positively correlated Potential biomarker potential biomarkers predict progression Protein Proteins regeneration serum Serum level serum levels severe COVID-19 patient severe COVID-19 patients severe patients severity severity of COVID-19 significantly increased targeted therapy the WHO to define was increased was reduced WHO World Health Organization [DOI] 10.1038/s41598-021-04677-8 PMC 바로가기 [Article Type] Clinical Trial
Pulmonary Mesenchymal Stem Cells in Mild Cases of COVID-19 Are Dedicated to Proliferation; In Severe Cases, They Control Inflammation, Make Cell Dispersion, and Tissue RegenerationImmunology Published on 2022-01-132022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] “cytokine storm” affected Alter Analysis biological function bronchoalveolar lavage sample CD40 Cell cell proliferation Cell therapy cell types chemotaxis clinical conditions Control COVID-19 COVID-19 patient Cytokine storm cytoplasmic Data analysis dispersion FHL2 Genes IFNGR1 IFNGR2 immune individual individuals induce inhibitor involved lung marker MDA5 mesenchymal stem cell Mild mild case mild COVID-19 patients MSC MSCs Necrosis NF-κB NFKBIA not express OPTN overexpression paracrine Patient performed PKR PPP2CB promote inflammation pulmonary receptors regeneration RNA secretion sequence Severe case severe COVID-19 single cell RNA sequencing single-cell RNA-seq STEM stem cell Target genes therapeutic therapeutic potential therapy for COVID-19 these cell tissue tlr-3 TLRs TNFR1 TNFR2 Transcription transcriptionally treat triggered upregulated upregulated gene upstream virus virus load [DOI] 10.3389/fimmu.2021.780900 PMC 바로가기 [Article Type] Immunology
Hypoxia-Inducible Factor Signaling in Inflammatory Lung Injury and RepairReview Published on 2022-01-062022-10-31 Journal: Cells [Category] Coronavirus, [키워드] acute lung injury acute respiratory distress AEC alveolar ARDS Cell cell type characteristic characterized condition conditions COVID-19 death disrupt ENhance epithelial expression Factor highlight hypoxia infiltrating Inflammatory inflammatory lung injury Injury isoform leukocyte infiltration leukocytes lung lung endothelial Lung injury Migration oxygen pathophysiological proliferation pulmonary reduce regeneration regulate Regulation repair severe coronavirus disease severe COVID-19 Side-effects Signaling survival syndrome target Target genes the timing therapeutic intervention therapy tissue transcription factor Transport turn variety Vascular [DOI] 10.3390/cells11020183 PMC 바로가기 [Article Type] Review
[Welche Behandlungsoptionen wurden von COVID-19-infizierten Yogaübenden als hilfreich empfunden? Ergebnisse einer Querschnittsanalyse][Welche Behandlungsoptionen wurden von COVID-19-infizierten Yogaübenden als hilfreich empfunden? Ergebnisse einer Querschnittsanalyse]Article Published on 2022-01-012022-09-11 Journal: Complementary medicine research [Category] 변종, [키워드] affected age Analysis assigned Befragung breathing exercise breathing exercises content Conventional cough coughs COVID-19 COVID-19 infection COVID-19-Infizierte cross-sectional analysis data set dominant Effectiveness eight English essential oil exercise Exhaustion followed by groups headache Headaches helplessness indication indications Infection measure medication MOST olfactory Pain Practitioner Pranayama recorded regeneration Selbstmanagement Self-management sense Shortness of breath Spectrum Supportive Behandlung supportive therapy Symptom Therapieoptionen therapy Treatment virus variant weakness were used yoga Yogaübende. [DOI] 10.1159/000524338 PMC 바로가기 [Article Type] Article
Endothelial dysfunction contributes to severe COVID-19 in combination with dysregulated lymphocyte responses and cytokine networks내피 기능 장애는 조절 이상 림프구 반응 및 사이토카인 네트워크와 함께 심각한 COVID-19에 기여합니다Observational Study Published on 2021-12-102022-09-10 Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, SARS, 바이오마커, 임상, 진단, 치료법, [키워드] activated Activation acute disease Adaptive immunity addition analyses Analysis change Clustering Combination contribute convalescent patient Convalescent patients COVID-19 cytokine disease Disease progression driven by dysfunction dysregulated dysregulation endothelial endothelial injury endothelial integrity expansion flow cytometry granulocyte Granulocytes hallmark hallmarks Hannover ICU patient ICU Patients Immune cell immune cells immune response immune responses immune signature Infectious diseases Inflammatory Inflammatory response Injury involved life-threatening lymphocyte response lymphopenia manifestation medical school microenvironment NK cell observational study plasma protein plasma proteins plasmablast plasmablasts proteomics data regeneration SARS-COV-2 infection SARS-CoV-2-specific antibodies School Seven severe COVID-19 terminally differentiated [DOI] 10.1038/s41392-021-00819-6 PMC 바로가기 [Article Type] Observational Study
Fetal Immunomodulatory Environment Following Cartilage Injury—The Key to CARTILAGE Regeneration?Article Published on 2021-11-302023-08-30 Journal: International Journal of Molecular Sciences [Category] E형 간염, [키워드] cartilage fetal immunomodulation Inflammation Macrophage neutrophil regeneration [DOI] 10.3390/ijms222312969 PMC 바로가기 [Article Type] Article
The Potential Contribution of Biopolymeric Particles in Lung Tissue Regeneration of COVID-19 PatientsReview Published on 2021-11-202022-10-28 Journal: The British journal of oral & maxillofacial surger [Category] COVID-19, [키워드] airway epithelial cell antibodies attack biopolymeric nanoparticles biopolymeric scaffolds Cell chemotherapeutic drugs components COVID-19 COVID-19 illness creating diagnostic effective example Gas exchange highlight Inflammation lung lung cell lung cells lung tissue nucleic acids organ Particle Potential Proteins regeneration resulting stem cells Symptom These cells tissue regeneration transfer Treatment Vaccines with COVID-19 [DOI] 10.3390/polym13224011 PMC 바로가기 [Article Type] Review
Immunomodulation and Regenerative Capacity of MSCs for Long-COVIDLong-COVID에 대한 MSC의 면역 조절 및 재생 능력Review Published on 2021-11-172022-09-12 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 진단, [키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome ARDS Capacity clinical clinical trial clinical trials Cytokine storm death edema Effect effective drug effective drugs eventually death immunomodulation immunomodulator include Inflammation long-COVID lung lung injuries Lung injury mesenchymal stem cell Mesenchymal stem cells MSC MSCs Mutation patients with COVID-19 Post-COVID-19 patients promote provided Pulmonary edema reduce regeneration regenerative regenerative properties respiratory distress SARS-CoV-2 virus severity syndrome the disease the SARS-CoV-2 virus therapy Treatment Trial Usage [DOI] 10.3390/ijms222212421 PMC 바로가기 [Article Type] Review
Inflammation, a common mechanism in frailty and COVID-19, and stem cells as a therapeutic approach노쇠와 COVID-19의 일반적인 메커니즘인 염증과 치료적 접근으로서의 줄기 세포Review Published on 2021-11-012022-09-11 Journal: Stem cells translational medicine [Category] SARS, 유전자 메커니즘, [키워드] aging approach cause of death Cell cellular senescence Combination COVID-19 death deteriorate difficulty effort Factor frailty global health Health health condition Hyperinflammatory immune system immunomodulation Increases Infection Inflammation Life expectancy limit mechanism medical condition Medical conditions mesenchymal stem cell molecular MSC Pathologies pathology Perspective producing proportion regeneration Research STEM stem cell stem cell exhaustion. stem cells Therapeutic approach therapy to define world population [DOI] 10.1002/sctm.21-0074 PMC 바로가기 [Article Type] Review