SIgA – Page 2 – Communicable Diseases Research

Secretory IgA and T cells targeting SARS-CoV-2 spike protein are transferred to the breastmilk upon mRNA vaccination

Report

Published on 2021-12-022022-10-31
Journal: Cell Reports Medicine [Category] COVID-19, SARS,

[키워드] Abstract Affect anti-RBD Anti-spike antibody antibody production Antibody titer BNT162b2 breastmilk breastmilk T cells circulating Combination Concentration controls COVID-19 cumulative determine effective evaluated Frequency functional IgA IgG immune protection immune response immune transfer induce lactating women mammary maternal vaccination memory B cell memory B cells milk-transferred SARS-CoV-2 protection milk-transferred spike-reactive T cells Moderna mRNA vaccination mRNA vaccine mRNA-1273 vaccine mucosa neutralization capacity neutralize Neutralizing neutralizing capacity occur Pfizer plasmablasts Protective RBD SARS-CoV-2 SARS-CoV-2 spike protein secretory secretory IgA SIgA spike SIgA transfer transferred vaccination
[DOI] 10.1016/j.xcrm.2021.100468 PMC 바로가기 [Article Type] Report

Detection of cross-reactive immunoglobulin A against the severe acute respiratory syndrome-coronavirus-2 spike 1 subunit in saliva

중증 급성 호흡기 증후군-코로나 바이러스 -2 스파이크에 대한 교차 반응성 면역 글로불린 A의 검출 1 타액의 서브 유닛

Research Article

Published on 2021-11-232022-09-10
Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료기술,

[키워드] age analyzed angiotensin angiotensin converting enzyme Angiotensin converting enzyme-2 binding Biotin blood sample Blood samples breast milk Chain Reaction correlated cross-react cross-reaction cross-reactive cross-reactivity dental dentist dentists detection determined by enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay help IgG and IgM Immunity immunochromatography Immunoglobulin immunoglobulin A individual Infection involved men mucosal surfaces Mucus Patient patients PCR PCR-negative polymerase chain polymerase chain reaction Prevent proportion Protein provide purified reaction receptor Receptor-binding domain reported Saliva saliva samples SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 spike protein secretory immunoglobulin A SIgA significantly lower Spike protein subunit suppress the receptor-binding domain university virus was determined women
[DOI] 10.1371/journal.pone.0249979 PMC 바로가기 [Article Type] Research Article

Inhibition of elastase enhances the adjuvanticity of alum and promotes anti–SARS-CoV-2 systemic and mucosal immunity

엘라스타제의 억제는 명반의 면역증강을 강화하고 항-SARS-CoV-2 전신 및 점막 면역을 촉진합니다.

423

Published on 2021-08-242022-09-12
Journal: Proceedings of the National Academy of Sciences of [Category] MERS, SARS, 진단,

[키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjuvant adjuvanticity alum alum adjuvant antibodies antibody Antibody Response Antibody responses Antigen Blood bloodstream blunt CD4 Cell-mediated immunity coronavirus COVID-19 patients Efficacy Elastase ENhance epitope Epitopes follicular help identify IgA antibodies IgA antibody IL-1 Immunity immunization Immunoglobulin IMPROVE induce inhibition inhibitor injected innate response interleukin investigated lack magnitude mice mucosal mucosal immunity mucosal route mucosal secretion mucosal tissue mucosal tissues myeloid cells neutrophil Neutrophil elastase neutrophil elastase inhibitor Neutrophils pharmacological promote protective antibodies Protective antibody Protein Protein subunit protein-based vaccine recruitment regulate response responses SARS-CoV-2 SARS-CoV-2 spike protein sera Serine serine protease serum antibody serum IgG severe acute respiratory syndrome Coronavirus SIgA Significance Spike protein stimulate subunit Support suppression T cell T cell responses T helper Tfh Th1 Th2 the spike protein vaccination Vaccine Vaccines
[DOI] 10.1073/pnas.2102435118 PMC 바로가기 [Article Type] 423

The Impact of Oral Health on Respiratory Viral Infection

Review

Published on 2021-04-132022-10-31
Journal: Dentistry Journal [Category] COVID-19,

In Nasal Mucosal Secretions, Distinct IFN and IgA Responses Are Found in Severe and Mild SARS-CoV-2 Infection

비강 점막 분비물에서 중증 및 경증 SARS-CoV-2 감염에서 뚜렷한 IFN 및 IgA 반응이 발견됨

Comparative Study

Published on 2021-02-252022-09-12
Journal: Frontiers in Immunology [Category] MERS, 진단,

Human Milk Antibodies against S1 and S2 Subunits from SARS-CoV-2, HCoV-OC43, and HCoV-229E in Mothers with a Confirmed COVID-19 PCR, Viral SYMPTOMS, and Unexposed Mothers

COVID-19 PCR, 바이러스성 증상 및 노출되지 않은 산모에서 SARS-CoV-2, HCoV-OC43 및 HCoV-229E의 S1 및 S2 소단위체에 대한 모유 항체

Article

Published on 2021-02-092022-09-10
Journal: International Journal of Molecular Sciences [Category] MERS, 진단, 치료기술,

[키워드] β-coronaviruses antibodies antibody Antigen antigens breast milk Breastfeeding Confirmed control group COVID-19 COVID-19 group COVID-19 pandemic COVID-19 PCR test cross-reactive cross-reactive antibodies cross-reactive antibody ELISA evaluate group groups HCoV HCoV-229E HCoV-OC43 HCoVs Human human milk IgG IgG levels IgM Immunity immunoglobulins Infectious diseases milk mother Neonates not differ OC43 passive immunity PCR PCR test polyreactive antibody positive correlation positive correlations Preexisting immunity reactive S1 and S2 S2 subunit SARS-CoV-2 SARS-CoV-2 IgG secretory antibodies secretory IgA SIgA subunit Symptom Symptoms Viral were measured α-coronaviruses
[DOI] 10.3390/ijms22041749 PMC 바로가기 [Article Type] Article

Virulence gene profiles of Shigella species isolated from stool specimens in India: its association with clinical manifestation and antimicrobial resistance

인도에서 분변 샘플에서 분리된 시겔라 종의 병원성 유전자 프로파일: 임상 증상 및 항균제 내성과의 연관성

Article

Published on 2019-06-212024-07-30
Journal: Pathogens and Global Health [Category] 세균성이질,

[키워드] ipaH lpfA sepA Shigella spp SIgA virulence
[DOI] 10.1080/20477724.2019.1632062 PMC 바로가기 [Article Type] Article

Mucosal immune responses induced by oral administration recombinant Bacillus subtilis expressing the COE antigen of PEDV in newborn piglets

Research Articles

Published on 2019-02-262022-10-28
Journal: Bioscience Reports [Category] Coronavirus, MERS,

[키워드] administration antibody Antigen B. subtilis Bacillus subtilis candidate vaccine cause CD3 CD4 cells COE Contact contagious demonstrated develop disease effective epidemic diarrhea evaluated expressing IgA IgG immune immune response immunization Immunoglobulin immunoglobulin A Infection Local lymphocyte mucosal mucosal immune mucosal immunity Newborn oral administration Oral vaccine PEDV Peyer’s patche Piglets Porcine epidemic diarrhea virus prevented recombinant Bacillus subtilis responses secreting serum SIgA significantly significantly increased Spread systemic immune response T cells up-regulated Vaccine Vaccines virus
[DOI] 10.1042/BSR20182028 PMC 바로가기 [Article Type] Research Articles

Oral administration of inactivated porcine epidemic diarrhea virus activate DCs in porcine Peyer’s patches

Research Article

Published on 2018-08-162022-10-28
Journal: BMC veterinary research [Category] Coronavirus,

Impact of TGEV infection on the pig small intestine

Research

Published on 2018-06-192022-10-28
Journal: Virology Journal [Category] Coronavirus,