Inhaled nitric oxide as temporary respiratory stabilization in patients with COVID-19 related respiratory failure (INOCOV): Study protocol for a randomized controlled trialCOVID-19 관련 호흡 부전(INOCOV) 환자의 일시적인 호흡 안정화로서 흡입된 산화질소: 무작위 대조 시험을 위한 연구 프로토콜Article Published on 2022-05-272022-09-11 Journal: PLoS ONE [Category] 임상, [키워드] Acute respiratory failure adjunct airway anaesthesia blinded Blood cause of death COVID-19 death deoxygenated described End-Expiratory Pressure EudraCT fraction global public health High-flow oxygen Hypoxemia hypoxia Inhaled initial intubation life-threatening lung Lungs management margin measure mechanical ventilation nitric oxide no difference null hypothesis oxygen oxygen saturation pandemic Patient patients with COVID-19 PEEP pharmacological Positive end-expiratory pressure predominant preoxygenation primary outcome measure protocol Randomized Randomized controlled trial reduce Respiratory failure safety margin sequence severe hypoxia Shunt SpO2 Standard of care Trial Two-arm Ventilation WHO [DOI] 10.1371/journal.pone.0268822 PMC 바로가기 [Article Type] Article
Partisanship, Messaging, and the COVID-19 Vaccine: Evidence From Survey ExperimentsRandomized Controlled Trial Published on 2022-05-012022-10-04 Journal: American journal of health promotion : AJHP [Category] COVID19(2023년), SARS, 임상, [키워드] 95% confidence interval adjusted odds ratio analyzed AOR COVID-19 COVID-19 vaccination COVID-19 vaccine Effect elite messaging experiment had no independent Likert scale Mann-Whitney U multivariate logistic regression partisanship. President produced Randomized reported respondent Significant significant effect Support survey the vaccine Two-arm vaccinate vaccination intention vaccination intentions widespread [DOI] 10.1177/08901171211049241 PMC 바로가기 [Article Type] Randomized Controlled Trial
Light acupuncture and five-element music therapy for nurses’ mental health and well-being during and post-COVID-19: protocol for a randomised cross-over feasibility study코로나19 기간 및 이후 간호사의 정신 건강과 웰빙을 위한 가벼운 침술 및 5요소 음악 요법: 무작위 교차 타당성 연구를 위한 프로토콜Article Published on 2022-04-292022-09-11 Journal: BMJ Open [Category] 임상, [키워드] affected Analysis Anxiety asked assessments Blinding clinical clinical trial Combination Community Complete COVID-19 pandemic cross-over Depression depression & dissemination Edith eligible engage Ethical approval Ethics ethics committee evaluate Evidence feasibility Feasibility study form Health healthcare professionals hospital Human Impact IMPROVE include Intention International Intervention Laser Laser therapy LIGHT Local management mental health mood disorders music therapy National New Nurse online questionnaire online questionnaires PAIN MANAGEMENT participant peer-reviewed performed Primary outcome profession protocol Quality of life randomised recruited registration number required Research Ethics research findings resulting secondary outcome Secondary outcomes Studio therapeutic effect therapy Treatment treatment group Trial Two-arm university Well-being [DOI] 10.1136/bmjopen-2021-057106 PMC 바로가기 [Article Type] Article
A parallel randomised controlled trial of the Hypoglycaemia Awareness Restoration Programme for adults with type 1 diabetes and problematic hypoglycaemia despite optimised self-care (HARPdoc) Research Published on 2022-04-282022-10-05 Journal: Nature Communications [Category] 임상, [키워드] Analysis Anxiety Attitude avoidance Awareness baseline blinded changes in cognitive conducted Depression diabete difference distress effective emotional Estimated Health Hypothesis Impaired insulin Measures outcome positive Primary outcome randomised randomised controlled trial rate ratio recall reduced reducing restoration risk secondary self-care significantly T1D Treatment Trial Two-arm [DOI] 10.1038/s41467-022-29488-x [Article Type] Research
Controlled evaLuation of Angiotensin Receptor Blockers for COVID-19 respIraTorY disease (CLARITY): statistical analysis plan for a randomised controlled Bayesian adaptive sample size trialRandomized Controlled Trial Published on 2022-04-272022-10-04 Journal: Trials [Category] 임상, [키워드] 7-point ordinal scale adaptive Adaptive sample size addition Analysis analysis plan angiotensin angiotensin receptor blocker Angiotensin receptor blockers Bayesian Bayesian design benefit blocker CLARITY clinical clinical status clinical trial Controlled coronavirus COVID-19 determine disease Effectiveness Evidence India intention-to-treat principle lung failure patients with COVID-19 Placebo primary analysis Primary outcome protocol randomised controlled randomised controlled trial receptor reducing registry Sample size severity standard care Statistical analysis plan Statistical analysis plan. the WHO Treatment effectiveness Trial Two-arm was selected [DOI] 10.1186/s13063-022-06167-2 PMC 바로가기 [Article Type] Randomized Controlled Trial
The UK stand together trial: protocol for a multicentre cluster randomised controlled trial to evaluate the effectiveness and cost-effectiveness of KiVa to reduce bullying in primary schoolsUK Stand Together Trial: 초등학교에서 괴롭힘을 줄이기 위한 KiVa의 효과와 비용 효율성을 평가하기 위한 다기관 클러스터 무작위 통제 시험 프로토콜Article Published on 2022-03-292022-09-11 Journal: BMC Public Health [Category] 임상, [키워드] 1:1 90% power Analysis assigned assumed baseline Bullying Burnout bystander Child child health children client Cluster Cluster randomised controlled trial commenced conducted Controlled trial cost-effectiveness COVID-19 pandemic Date East Economic evaluation effective Effectiveness emotional England evaluate Evidence evidence of Follow-up Frequency generate Health ICC identify implementation indicated influences influences on Intervention inventory ISRCTN KiVa mechanisms Mental mental health multicentre North Perspective Pragmatic Process process evaluation protocol public health questionnaire randomised randomised controlled randomised controlled trial receipt recruited reduce reducing reduction reported resulting Sample Sample size scalability School school attendance School intervention School meal Schools secondary Self-efficacy service significance level South stratified Trial Two-arm Violence prevention Violence prevention. Well-being West [DOI] 10.1186/s12889-022-12642-x PMC 바로가기 [Article Type] Article
Behavioural Activation for Social IsoLation (BASIL+) trial (Behavioural activation to mitigate depression and loneliness among older people with long-term conditions): Protocol for a fully-powered pragmatic randomised controlled trialBASIL+(사회적 고립을 위한 행동 활성화) 시험(장기 조건을 가진 노인의 우울증과 외로움을 완화하기 위한 행동 활성화): 완전한 실용주의 무작위 통제 시험을 위한 프로토콜Article Published on 2022-03-242022-09-11 Journal: PLoS ONE [Category] 임상, [키워드] 1:1 acceptability Activation Adults Anxiety BASIL build Care clinical clinically ClinicalTrials collected conducted consequence Control Controlled trial COVID-19 COVID-19 pandemic Depression depressive symptom Depressive symptoms eight eligible England evaluate evaluated for inclusion Health health problem Health Service include increased risk information Intervention Isolation life loneliness Long-term condition long-term conditions Mental mental health mitigate Older outcome parallel-group participant Participants physical physically Pragmatic Primary outcome Psychological intervention Quality of life questionnaire randomisation randomised controlled trial receive recruited Registered Research scored secondary Secondary outcomes self-help social isolation stratified Support supported Trial Two-arm usual care worker [DOI] 10.1371/journal.pone.0263856 PMC 바로가기 [Article Type] Article
FOODLIT-Trial: Protocol of a Randomised Controlled Digital Intervention to Promote Food Literacy and Sustainability Behaviours in Adults Using the Health Action Process Approach and the Behaviour Change Techniques Taxonomy during the COVID-19 PandemicFOODLIT-Trial: COVID-19 팬데믹 기간 동안 건강 행동 프로세스 접근 및 행동 변화 기법 분류를 사용하여 성인의 음식 문해력 및 지속 가능성 행동을 촉진하기 위한 무작위 통제 디지털 개입 프로토콜Article Published on 2022-03-162022-09-11 Journal: International Journal of Environmental Research an [Category] 임상, [키워드] Action Analysis approach baseline Behaviour change Behaviour Change Techniques Taxonomy change Community conducted Controlled Controlled trial cost-effective intervention COVID-19 COVID-19 pandemic dietary Digital effective ENhance experimental group FIVE food food literacy HAPA health action process approach hypothesised include intention-to-treat International Intervention knowledge linear literacy long term mechanism Mediation analysis multidimensional outcome participant Participants post-intervention predict Primary outcome Process promote protocol Psychological randomisation randomised controlled trial secondary outcome supported sustainability taxonomy technique treat Two-arm Wheel [DOI] 10.3390/ijerph19063529 PMC 바로가기 [Article Type] Article
Immune response to one dose of BNT162b2 mRNA Covid-19 vaccine followed by SARS-CoV-2 infection: An Italian prospective observational studyObservational Study Published on 2022-03-152022-10-05 Journal: Vaccine [Category] COVID19(2023년), SARS, 임상, [키워드] anti-SARS-CoV-2 Antibody Response Biological biological risk BNT162b2 mRNA vaccine carried categories control group COVID-19 dose European country first dose geometric mean titer GMT HCW HCWs Health healthcare worker Healthcare workers immunization immunized individual Infection initiated Italian Italy mRNA Observational cohort study of BNT162b2 positive PPE prospective observational study risk SARS-CoV-2 serological statistically significant difference surveillance data tested the antibody response the vaccine Two-arm vaccination Vaccinations Vaccine vaccine group was determined were infected [DOI] 10.1016/j.vaccine.2022.02.002 PMC 바로가기 [Article Type] Observational Study
Uptake of the multi-arm multi-stage (MAMS) adaptive platform approach: a trial-registry review of late-phase randomised clinical trialsRandomized Controlled Trial Published on 2022-03-102022-10-05 Journal: BMJ Open [Category] Coronavirus, 임상, [키워드] accelerated adaptive African approach Arm ARMS assist Cancer Characteristics clinical clinical pharmacology clinical trial clinical trials Cochrane Library Controlled COVID-19 defined disease examined global health highlight Infectious disease Infectious diseases interim analysis Intervention intervention arms knowledge library majority medical condition medication medications multi-arm New number oncology Pan platform Platform trial PROSPERO public health randomised randomised clinical trial recruitment Registered registry Research stages Standard treatment interventions Trial trials Two-arm uptake was performed WHO [DOI] 10.1136/bmjopen-2021-055615 PMC 바로가기 [Article Type] Randomized Controlled Trial