First Case of COVID-19 Treated with Monoclonal Anti-Spike Antibodies in a Patient with Cystic Fibrosis in RomaniaCase Report Published on 2022-01-072022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Administered allergies Casirivimab chronic condition close monitoring Comorbidities Complication conditions cough COVID-19 Critical Cystic cystic fibrosis decrease Evolution extrasystole fibrosis foci hemoptysis Imdevimab Inflammatory interstitial pneumonia lung Lung imaging male Moderate COVID-19 monoclonal anti-spike antibodies monoclonal antibody multidrug resistant nasal pancreatic positive RT-PCR progression Pseudomonas aeruginosa repeated required Romania SARS-CoV-2 severe COVID-19 syndrome therapeutic intervention Treatment underlying conditions ventricular [DOI] 10.3390/diagnostics12010137 PMC 바로가기 [Article Type] Case Report
Clinical Characteristics, Diagnosis, Treatment, and Mortality Rate of TB/COVID-19 Coinfectetd Patients: A Systematic ReviewMedicine Published on 2021-12-012022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] addition Case report case sery cause Characteristics China clinical Coinfection collected Comorbidity coronavirus cough COVID-19 COVID-19 epidemic COVID-19 patient COVID-19-related death diabete diagnosed died discharged patient distress enrolled Epidemic Fever health system hypertension India indicated less limitation majority material men Mortality mortality rate National novel Patient patients Prevalence Prevent Rate respiratory symptom review screened severity Spread suffered TB TB patient the disease Threats Treatment Tuberculosis underlying conditions was performed Web of Science with COVID-19 women worsening [DOI] 10.3389/fmed.2021.740593 PMC 바로가기 [Article Type] Medicine
Early Treatment for Covid-19 with SARS-CoV-2 Neutralizing Antibody SotrovimabSARS-CoV-2 중화항체 소트로비맙으로 코로나19 조기 치료Randomized Controlled Trial Published on 2021-11-182022-09-25 Journal: The New England Journal of Medicine [Category] meta-analysis, SARS, 바이오마커, 변종, 비임상, 신약개발, 유전자 메커니즘, 임상, 진단, 치료기술, 치료법, 치료제, [키워드] 1:1 Adverse assigned Biotechnology confidence interval Coronavirus disease 2019 Course death died disease Disease progression dose double-blind Efficacy event high-risk patient Hospitalization intensive care intention-to-treat population interim analysis less Mild-to-moderate monoclonal antibody multicenter older patient onset of symptoms outcome Patient patients phase 3 trial Placebo Prevent progression randomization Randomly receive reduced reported risk risk factor risk reduction Safety SARS-CoV-2 Serious Adverse Event Sotrovimab symptomatic COVID-19 the patient the placebo group underlying conditions Vir [DOI] 10.1056/NEJMoa2107934 [Article Type] Randomized Controlled Trial
Near-Complete Genome of SARS-CoV-2 Delta (AY.3) Variant Identified in a Dog in Kansas, USASARS-COV-2 델타의 거의 완전한 게놈 (AY.3) 변형은 미국 캔자스의 개에서 확인Article Published on 2021-10-192022-09-10 Journal: Viruses [Category] MERS, SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Analysis animal AY.3 canine change characterization Cluster coding region Collie Consensus coronavirus COVID-19 COVID-19 disease Delta delta variant description dog house Human Identified infecting Infection Local outbreak Phylogenetic positive respiratory SARS-CoV-2 SARS-CoV-2 genome SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants sequence sequenced severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 susceptibility Symptom tested Transmission underlying conditions unique USA variant virus whole genome sequence [DOI] 10.3390/v13102104 PMC 바로가기 [Article Type] Article
COVID19-related and all-cause mortality risk among middle-aged and older adults across the first epidemic wave of SARS-COV-2 infection: a population-based cohort study in Southern Catalonia, Spain, March–June 2020Research Published on 2021-10-062022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, SARS, [키워드] 95% confidence interval age all-cause mortality analyses Cancer causes Cohort cohort characteristics cohort study Comorbidity coronavirus COVID-19 COVID-19 pandemic COVID19 Cox regression death deaths Deceased died Direct diuretics epidemic wave explain false negative result First wave greater hazard ratio increased risk Increasing individual inhibitor investigated laboratory-confirmed Liver disease male Mortality mortality rate mortality risk multivariable analysis neurologic occurred Older outcome pandemic Patient patients PCR testing PCR-negative population-based cohort predictor proportion proton-pump inhibitor receiving reduced risk Result risk SARS-CoV-2 Sex significantly socio-demographic Spain study period subject subjects suffered supplementary material systemic corticosteroids underlying conditions were assessed with COVID-19 [DOI] 10.1186/s12889-021-11879-2 PMC 바로가기 [Article Type] Research
Characteristics, Comorbidities, and Data Gaps for Coronavirus Disease Deaths, Tennessee, USA코로나바이러스 질병 사망에 대한 특성, 동반 질환 및 데이터 격차, 테네시주, 미국Review Published on 2021-10-012022-09-10 Journal: Emerging Infectious Diseases [Category] MERS, SARS, 치료기술, [키워드] black Black patients capita Comorbidities Comorbidity coronavirus coronavirus disease Coronaviruses COVID-19 COVID-19 pandemic Data collection death Deceased Department diabetes died disease Epidemiology Ethnic groups except for Gap had no highest Hispanic patients information Investing male mortality rates Older Outbreaks Patient population characteristics proportion public health public health surveillance recorded respiratory infections SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Surveillance survived Tennessee The United States underlying condition underlying conditions United States USA viruses White patients zoonoses [DOI] 10.3201/eid2710.211070 PMC 바로가기 [Article Type] Review
Response to the COVID-19 Pandemic: Comparison of Strategies in Six CountriesPublic Health Published on 2021-09-302022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, SARS, [키워드] adopted approach available data China confirmed case containment measures containment strategies Containment strategy countries comparison country COVID-19 Effectiveness Epidemic France individual level infected patient measure Mitigation strategy mortality rate not significant outbreak pandemic per day public health response Severe case Singapore South Korea Spread Strategy the epidemic The United States underlying conditions United Kingdom United State website [DOI] 10.3389/fpubh.2021.708496 PMC 바로가기 [Article Type] Public Health
Accumulation of CD28 null Senescent T-Cells Is Associated with Poorer Outcomes in COVID19 PatientsCD28 널 노화 된 T- 세포의 축적은 COVID19 환자의 불량한 결과와 관련이 있습니다.Review Published on 2021-09-292022-08-31 Journal: Biomolecules [Category] 바이오마커, 유전자 메커니즘, [키워드] accumulation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adverse outcome adverse outcomes aging array Asymptomatic Cancer cause CD28 CD28null T-cells Cell chronic obstructive chronic obstructive pulmonary disease chronic obstructive pulmonary disease (COPD) condition COPD coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID19 cytotoxicity death diabetes disease expansion hypertension immune decline individual Infection Infectious disease Inflammation inflammatory conditions morbidity and mortality mortality rates null cells obstructive pulmonary disease Patient populations potential mechanism potential mechanisms pulmonary disease respiratory Risk factors SARS-CoV-2 senescence senescent severe acute respiratory syndrome Coronavirus severity of COVID-19 Severity of infection Symptom T-cell T-cells Treatment underlying conditions [DOI] 10.3390/biom11101425 PMC 바로가기 [Article Type] Review
Autoimmune neutropenia associated with influenza virus infection in childhood: a case reportCase Report Published on 2021-08-182022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, [키워드] antibody Autoimmune neutropenia Blood Case report characterized childhood children Conservative management cough Course diagnosed disorder etiology Fever hematological Infant Infection influenza infection Influenza virus life-threatening male management mutations nasopharyngeal neutropenia Neutrophils performed positive Rapid test reported severe infections subsequent the disease Treatment triggered underlying conditions viral infection [DOI] 10.1186/s12879-021-06506-9 PMC 바로가기 [Article Type] Case Report
COVID-19 and underlying health conditions: A modeling investigationArticle Published on 2021-08-052022-10-31 Journal: Mathematical biosciences and engineering : MBE [Category] COVID-19, MERS, SARS, [키워드] approach chronic conditions chronic health condition conditions Contact COVID-19 COVID-19 transmission Data fitting effective groups Health high risk Host mathematical Prevalence PROTECT reduction susceptible individuals the disease total population Transmission Transmission dynamics two groups underlying conditions [DOI] 10.3934/mbe.2021191 PMC 바로가기 [Article Type] Article