A method comparison study of the high throughput automated HISCL® SARS-CoV-2 antigen assay using nasopharyngeal swab samples from symptomatic and asymptomatic subjects against conventional RT-PCR기존의 RT-PCR에 대한 증상 및 무증상 피험자의 비인두 면봉 샘플을 사용한 고속 자동화 HISCL® SARS-CoV-2 항원 분석의 방법 비교 연구Article Published on 2022-07-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval 95%CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antigen automated Chain Reaction collected compatibility coronavirus cycle threshold evaluate healthcare worker Healthcare workers HISCL automated antigen assay individual Infection medium method comparison Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples polymerase chain polymerase chain reaction public health rapid testing RT-PCR SARS-CoV-2 SARS-CoV-2 antigen sensitivity severe acute respiratory syndrome Coronavirus specificity subject Swab swabs symptomatic and asymptomatic tested Transport transport medium Universal Transport Medium UTM variants variants of concern variants of concern. viral loads viral spread yielding [DOI] 10.1002/jmv.27679 PMC 바로가기 [Article Type] Article
Transmission of B.1.617.2 Delta variant between vaccinated healthcare workers예방 접종을 받은 의료 종사자 간의 B.1.617.2 Delta 변이의 전파Article Published on 2022-06-212022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] analysed approach B.1.617.2 benefit breakthrough infections Care Computational approaches delta variant described dose eight epidemiological HCW HCWs Health Health care Health care worker health care workers healthcare worker highlight hospital India individual Infection infection control less likelihood measure Patient populations potential for transmission Probability Re-infections recipient reduce reported SARS-CoV-2 sequence Transmission transmissions transmitted vaccination Vaccine viral spread virus genome virus transmission [DOI] 10.1038/s41598-022-14411-7 PMC 바로가기 [Article Type] Article
Detection of SARS-CoV-2 RNA on surfaces in a COVID-19 hospital ward indicates airborne viral spreadCOVID-19 병원 병동의 표면에서 SARS-CoV-2 RNA의 검출은 공기 중 바이러스 확산을 나타냅니다Article Published on 2022-06-012022-09-11 Journal: The Journal of hospital infection [Category] COVID19(2023년), SARS, 치료기술, [키워드] COVID-19 detection hospital ward indicate SARS-CoV-2 RNA viral spread [DOI] 10.1016/j.jhin.2022.02.025 PMC 바로가기 [Article Type] Article
Aptamer Sandwich Lateral Flow Assay (AptaFlow) for Antibody-Free SARS-CoV-2 Detection항체가 없는 SARS-CoV-2 검출을 위한 앱타머 샌드위치 측면 흐름 분석(AptaFlow)Article Published on 2022-05-242022-09-11 Journal: Analytical Chemistry [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Antigen approach aptamer bind binding Concentration contagious COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines detect detection DNA ELISA Flow Health high affinity identify immunoassay infected individuals Lateral lateral flow limit N-terminal domain NTD Probability provide Sandwich SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 virus Spike protein the SARS-CoV-2 Transmission Viral Viral load viral spread virus [DOI] 10.1021/acs.analchem.2c00554 PMC 바로가기 [Article Type] Article
Defining SARS-CoV-2 breakthrough infection needing hospitalization in mass vaccination era: from disease-centered to patient-centered care대량 백신 접종 시대 입원이 필요한 SARS-CoV-2 돌발 감염 정의 : 질병 중심에서 환자 중심으로Article Published on 2022-05-112022-09-11 Journal: Acta bio-medica : Atenei Parmensis [Category] COVID19(2023년), SARS, 변종, [키워드] Breakthrough infection breakthrough infections Care Clinical course Clinical severity Comorbidities COVID-19 COVID-19-related symptom COVID-19-related symptoms Epidemiology hospital hospital care Hospitalization implementation IMPROVE increasingly Infection intrinsic mass vaccination measure number of comorbidities organization Patient Post-vaccine SARS-CoV-2 SARS-COV-2 infection subjects vaccination variants viral spread [DOI] 10.23750/abm.v93i2.12717 PMC 바로가기 [Article Type] Article
Impacts of the COVID-19 pandemic on elective cataract surgeriesCOVID-19 전염병이 선택적 백내장 수술에 미치는 영향Article Published on 2022-05-062022-09-11 Journal: Einstein [Category] COVID19(2023년), SARS, 치료기술, [키워드] added adopted asymptomatic patients Brazil Cataract COVID-19 COVID-19 pandemic cross-sectional detect evaluate Impact IMPROVE Laboratory test Laboratory tests Local mail Mask measure media methylcellulose mitigate MOST ophthalmology Participants Patient performed Phacoemulsification Prevent Protective Quantitative questionnaire respiratory symptom respiratory symptoms risk significantly social media surgeon surgery surgical temperature the patient Transmission understanding verification viral spread Viral transmission was measured [DOI] 10.31744/einstein_journal/2022AO6687 PMC 바로가기 [Article Type] Article
The battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies숙주와 SARS-CoV-2의 전투: 선천 면역과 바이러스 회피 전략Review Published on 2022-05-042022-09-11 Journal: Molecular therapy : the journal of the American So [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, 치료제, [키워드] activated Antiviral antiviral gene antiviral genes antiviral targets caused confirmed cases COVID-19 death Defense evade highlight Host host response immune immune evasion immune surveillance Immunity Inflammation Innate innate immune innate immune response innate immune system Innate immunity interferon interferons Invasion knowledge life cycle mechanism pathogen Pattern recognition pattern recognition receptor Pattern recognition receptors PRRs recognizing Replication restrict resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus Signaling signaling cascade signaling transduction. Surveillance transduction type I type I and III interferons viral life cycle viral spread [DOI] 10.1016/j.ymthe.2022.02.014 PMC 바로가기 [Article Type] Review
A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection modelSARS-CoV-2 감염 모델에서 질병으로부터 보호하는 한 쌍의 비경쟁 중화 인간 단일클론 항체Article Published on 2022-05-012022-09-11 Journal: European Journal of Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] analysis animals antibodies antibody binding candidate cellular receptor cellular receptor hACE2 Cluster competing COVID-19 disease DNA DNA sequence hACE2 human ACE2 human immunoglobulin human monoclonal antibodies Human monoclonal antibody IC50 Immunoglobulin mice N-terminal domain neutralize neutralized Neutralizing Neutralizing antibodies neutralizing antibody pandemic platform powerful tool Prophylaxis Receptor-binding domain reduced SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 mutant SARS-CoV-2 mutants SARS-CoV-2 neutralizing antibody SARS-CoV-2 spike protein selected Spike protein Support the receptor-binding domain the SARS-CoV-2 the spike protein therapy transgenic variants variants of concern variants of concern. Viral viral spread weight loss [DOI] 10.1002/eji.202149374 PMC 바로가기 [Article Type] Article
Low-Dose SARS-CoV-2 S-Trimer with an Emulsion Adjuvant Induced Th1-Biased Protective Immunity저용량 SARS-CoV-2 S-삼량체(에멀젼 보조제 유도 Th1 편향 보호 면역 포함)Article Published on 2022-04-282022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] ACE2 binding addition adjuvant alum aluminum aluminum hydroxide Antibody Response Antigen Antisera B cell B cells Beta binding affinity Cellular immune response clinical testing comparable Complete COVID-19 pandemic Delta demonstrated different dose different doses effective Efficacy Emulsion ENhance evaluated exhibit feasible follicular Germinal center herd immunity humoral immune response hydroxide immune responses Immunity immunogenicity induce induced Infection Lineage live SARS-CoV-2 low dose lower dose mass vaccination mice Mutation Neutralizing antibodies neutralizing antibody prefusion Prevent produced Protective protein subunit vaccine rodent rodents Safe SARS-CoV-2 Subunit vaccine Support sustained SWE T-cell T-cell responses T-cells Tfh the antibody response These data trimer utility vaccination Vaccinations Vaccine vaccine. variant variants Viral viral infection viral spread were assessed [DOI] 10.3390/ijms23094902 PMC 바로가기 [Article Type] Article
Decoupling between SARS-CoV-2 transmissibility and population mobility associated with increasing immunity from vaccination and infection in South America남미에서 예방 접종 및 감염에 대한 면역력 증가와 관련된 SARS-CoV-2 전염성과 인구 이동성 간의 분리Article Published on 2022-04-272022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] analysis analyzed Brazil circulating correlated country coupling Decoupling driven by effective Epidemic epidemic wave expansion expected Formula Gamma herd immunity Herd immunity threshold Immunity Infection interactions Lambda National natural infection occurred Population Reproduction number SARS-CoV-2 SARS-CoV-2 variant severe COVID-19 South South America Southern Cone Spread Support text Transmissibility vaccination variant variants viral spread Viral transmission [DOI] 10.1038/s41598-022-10896-4 PMC 바로가기 [Article Type] Article