Increasing impact of COVID-19 on young adults: evidence from hospitalisations in Brazil젊은 성인에 대한 COVID-19의 영향 증가: 브라질 입원의 증거Article Published on 2021-09-012022-09-11 Journal: Public health [Category] SARS, 변종, [키워드] absence activity Adults age Age structure Analysis Brazil changed changes in concern conditions consequence control limit COVID-19 COVID-19 hospitalisation database dropped epidemiological Evidence examined exposure to financial support Government group hospitalisation hospitalisations hospitalised illness include Increasing individual Life expectancy limit longitudinal study magnitude Older pandemic Potential reached reduced Rejuvenation Rejuvenation trend. respiratory severe COVID-19 statistical Support surpassed transmissible variant vaccination Variation were used zone [DOI] 10.1016/j.puhe.2021.08.002 PMC 바로가기 [Article Type] Article
Topical hypochlorous acid (HOCl) blocks inflammatory gene expression and tumorigenic progression in UV-exposed SKH-1 high risk mouse skin국소 차아염소산(HOCl)은 UV에 노출된 SKH-1 고위험 마우스 피부에서 염증성 유전자 발현 및 종양 발생 진행을 차단합니다Article Published on 2021-09-012022-09-11 Journal: Redox Biology [Category] SARS, 유전자 메커니즘, [키워드] addition Analysis AP-1 atopic dermatitis bioluminescent block blocked Cancer Carcinogenesis clinical evidence combinations condition consequence COVID-19 pandemic drinking water elicited environmental exposure example exposure to finding Gene Expression Gene expression analysis high risk HMOX1 HOCl hypochlorous acid Il19 Immunohistochemical analysis Inflammation Inflammatory inflammatory signaling investigated luciferase mice mimicking modulation molecular murine model NOS2 observation oxidative stress oxidizing Pathway-focused gene expression profiling performed progression psoriasis PTGS2 public health Radiation reconstructed released skin skin cancer Solar Solar UV radiation. Srxn1 Stress stress response subsequent Support suppressed suppression Swimming pool therapeutic therapeutic intervention These data TLR4 Topic topical transgenic ultraviolet water [DOI] 10.1016/j.redox.2021.102042 PMC 바로가기 [Article Type] Article
Serosurvey for Health-Care Workers Provides Supportive Evidence for the Effectiveness of Hydroxychloroquine Prophylaxis against SARS-CoV-2 Infection의료 종사자를 위한 혈청 조사는 SARS-CoV-2 감염에 대한 하이드록시클로로퀸 예방의 효과에 대한 뒷받침되는 증거를 제공합니다Observational Study Published on 2021-09-012022-09-11 Journal: Journal of Epidemiology and Global Health [Category] SARS, 임상, 치료기술, [키워드] 95% CI acute respiratory syndrome coronavirus aerosol-generating procedures affecting Analysis anti-SARS-CoV-2 IgG antibody Antibody detection asymptomatic infection Care co-morbidities Combination conducted contributing to coronavirus 2 correlation COVID COVID-19 COVID-19 patient COVID-19 patients cross-sectional Dombivli ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay exposure to Factor HCQ HCW HCWs healthcare Healthcare workers high risk Hydroxychloroquine IgG antibodies IgG antibody incidence India Infection infection control Measures morbidities Multivariate analysis Mumbai nosocomial Nosocomial transmission observational study pandemic PPE Prophylaxis Providing reducing respiratory robust SARS-CoV-2 SARS-CoV-2 IgG antibodies SARS-CoV-2 IgG antibody SARS-COV-2 infection SARS-CoV-2 seroprevalence second wave Sero-surveillance Seropositivity Seroprevalence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe disease severity social distancing Spread study participant Study participants study population Symptom systematic analysis tested Transmission vaccination vulnerability was performed worker [DOI] 10.2991/jegh.k.210518.001 PMC 바로가기 [Article Type] Observational Study
Infant Exposure to Dolutegravir Through Placental and Breast Milk Transfer: A Population Pharmacokinetic Analysis of DolPHIN-1태반 및 모유 전달을 통한 Dolutegravir에 유아 노출 : Dolphin-1의 인구 약동학 분석Online Only Articles Published on 2021-09-012022-09-06 Journal: Clinical Infectious Diseases: An Official Publicat [Category] Communicable Disease, [키워드] 1:1 Breast breast milk breastmilk contributed CORD covariate covariates Coverage described diagnosed dolutegravir efavirenz Effect elimination rate evaluate exposure to fetal gestation HIV Human immunodeficiency virus immunodeficiency virus Infant infant pharmacokinetics inhibitory concentration investigated Maternal maternal plasma median median time milk mixed-effects modeling participant pharmacokinetic plasma plasma sample Population Population pharmacokinetics predicted Pregnancy presenting Prevent profiles Prophylactic Prophylaxis provided Randomized Rapid reduction in Result South Africa switch therapy threshold Transmission treatment initiation Uganda umbilical Umbilical cord waned was used women [DOI] 10.1093/cid/ciaa1861 PMC 바로가기 [Article Type] Online Only Articles
Airborne transmission of respiratory viruses호흡기 바이러스의 공중 전염Review Published on 2021-08-272022-09-10 Journal: Science (New York, N.y.) [Category] MERS, SARS, 유전자 메커니즘, [키워드] activities acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 advance aerosol aerosol transmission Aerosols affected affecting airflow alveolar breathing can not CDC center characterized Contact contact with contaminated surface contaminated surfaces contribute Control coronavirus cough coughing coughs COVID-19 COVID-19 pandemic CREDIT Critical defined description disease control Diseases distance dominant droplet droplets emitter enrichment environmental factors Evidence exhale experiments expiratory exposure to Factor filtration fomite fraction Frequency Health Organization Height Host hosts Human rhinovirus Improved increasingly individual infected individual infected individuals infecting Infection infectious infectious viruses Influenza Influenza virus inhalation Inhaled Intervention involved knowledge lack less limitation Lungs majority Mask Masks measure Measures mechanism MERS Middle East Middle East respiratory syndrome mitigate new infection new infections occur other respiratory virus Other respiratory viruses Outbreaks pandemic pathogen Pathogens pathway penetrate phase Physicochemical properties physicochemical property prevalent prevention produced provided Radiation reduce relative contribution relative contributions Relative humidity respiratory respiratory aerosols respiratory droplet Respiratory droplets respiratory infections respiratory pathogen Respiratory pathogens respiratory syncytial virus respiratory tract respiratory virus respiratory viruses review rhinovirus robust RSV SARS-CoV SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus shown sneeze sneezes Spread superspreading event syndrome temperature thought through contact Transmission transmission of SARS-CoV-2 transmission pathway transmission pathways transmitted Transport transported Travel ultraviolet Ultraviolet radiation upper airway velocity Ventilation virus viruses WHO World Health Organization [DOI] 10.1126/science.abd9149 PMC 바로가기 [Article Type] Review
SARS-CoV-2 Antibody Isotypes in Systemic Lupus Erythematosus Patients Prior to Vaccination: Associations With Disease Activity, Antinuclear Antibodies, and Immunomodulatory Drugs During the First Year of the Pandemic예방 접종 전 전신 홍반성 루푸스 환자의 SARS-CoV-2 항체 아이소타입: 유행병 첫 해 동안 질병 활성, 항핵항체 및 면역조절 약물과의 연관성Immunology Published on 2021-08-272022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료기술, [키워드] a minor Activation activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 albumin all subjects analyzed anti-dsDNA antibodies antibody antibody isotypes Antibody Response antinuclear antibodies antinuclear antibody Arthritis Blood Blood Group BMI Cell cell receptor collected complement Complement activation complement-immunological terms coronavirus coronavirus disease Coronavirus disease 2019 correlated Course COVID-19 COVID-19-related symptom dose drug Effects ELISA envelope protein exposure to Fever followed by glucocorticoid Hydroxychloroquine IgA IgG IgM Impact include individual Infection interferon investigated isotype longitudinal samples Lupus lupus (SLE) lupus erythematosus minor multiplex neutralization (effect of) neutralizing capacity objective pandemic Patient patients with SARS-CoV-2 PCR-confirmed progression proportion Proteins respiratory Result Rheumatic diseases rheumatologist risk SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection serological severe acute respiratory syndrome Coronavirus severe SARS severe SARS-CoV-2 SLE SLE patient smoking steroid Steroids subject Swedish Symptom systemic systemic lupus erythematosus the cell Thromboembolism type I interferon use of hydroxychloroquine vaccination were measured women Year [DOI] 10.3389/fimmu.2021.724047 PMC 바로가기 [Article Type] Immunology
COVID-19 Screening by Anti-SARS-CoV-2 Antibody Seropositivity: Clinical and Epidemiological Characteristics, Comorbidities, and Food Intake QualityAnti-SARS-CoV-2 항체 혈청 양성에 의한 COVID-19 스크리닝: 임상 및 역학적 특성, 동반 질환 및 식품 섭취 품질Article Published on 2021-08-262022-09-10 Journal: International Journal of Environmental Research an [Category] MERS, SARS, 진단, 치료기술, [키워드] alternative Anosmia antibody Antibody test antibody tests applied association Blood Blood Group blood type both groups carried Characteristics clinical Clinical characteristics coughing country COVID-19 detect Developing diabete diabetes diagnostic diagnostic testing distress exposure to fat food Food Intake food intake quality groups in both groups individual Influenza influenza vaccination intake joint joint pain lack molecular muscle pain negative test no differences Pain Polyunsaturated positive prevalent protective factor Quality reported resources respiratory distress risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection Screening Serological testing seropositive Support Symptom vaccination with COVID-19 [DOI] 10.3390/ijerph18178995 PMC 바로가기 [Article Type] Article
Robust Antibody Responses to the BNT162b2 mRNA Vaccine Occur Within a Week After the First Dose in Previously Infected Individuals and After the Second Dose in Uninfected IndividualsBNT162b2 mRNA 백신에 대한 강력한 항체 반응은 이전에 감염된 개인의 경우 첫 번째 접종 후 일주일 이내에, 감염되지 않은 개인의 경우 두 번째 접종 후 발생Immunology Published on 2021-08-262022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료법, [키워드] acquired immunity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age Analysis Anti-nucleocapsid antibodies anti-nucleocapsid antibody Anti-spike anti-spike and anti-nucleocapsid antibodies antibody Antibody Response Antibody responses Antibody titre antibody titres Blood blood sample Blood samples BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccine collected conducted coronavirus coronavirus disease COVID-19 exposure to first dose FIVE genders HCW HCWs Health care Health care worker immunisation Immunity increase in Incubation period individual infected individuals Kinetics mRNA vaccine occurred offer pandemic path Patient respiratory response restrict viral replication Result robust SARS-CoV-2 second second dose second vaccination serological analysis severe acute respiratory syndrome Coronavirus Severity of disease Spike protein the spike protein titre Trigger vaccinated individual vaccinated individuals vaccination Viral viral replication virus was performed Week [DOI] 10.3389/fimmu.2021.722766 PMC 바로가기 [Article Type] Immunology
Efficacy of Unsupervised Self-Collected Mid-Turbinate FLOQSwabs for the Diagnosis of Coronavirus Disease 2019 (COVID-19)코로나 바이러스 질병의 진단을위한 감독되지 않은 자체 수집 된 중간-터지니어 플로 크 스웨이 (Covid-19)의 효능Article Published on 2021-08-222022-09-01 Journal: Viruses [Category] MERS, 진단, [키워드] Accuracy acute respiratory syndrome Analysis Care clinic collected coronavirus disease Coronavirus disease 2019 COVID-19 Diagnosis diagnosis of SARS-CoV-2 diagnostic dry swab Efficacy enrolled exposure to Health Health care health care workers Infection Laboratory medium Molecular diagnosis Nasopharyngeal swab nasopharyngeal swabs offer outbreak pandemic reducing respiratory room temperature SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus SARS-CoV-2 virus infection severe acute respiratory syndrome coronavirus-2 specimen Surveillance Swab swabs temperature the SARS-CoV-2 virus to define Transmission transported Travel unsupervised self-collection virus infection without affecting [DOI] 10.3390/v13081663 PMC 바로가기 [Article Type] Article
COVID19-associated cardiomyocyte dysfunction, arrhythmias and the effect of CanakinumabCOVID19 관련 심근 세포 기능 장애, 부정맥 및 카나 키누맙의 효과Research Article Published on 2021-08-192022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 신약개발, 진단, [키워드] addition aims amplitude Anti-inflammatory therapy approach ARDS arrhythmia Arrhythmias baseline canakinumab cardiac function cardiac injury Cell cellular Co-incubation coronavirus coronavirus disease COVID19 COVID19 patient COVID19 patients cytokine cytokine release cytosolic decrease dysfunction Effect electrical evaluated event exposure to had no ICU IL-1β impaired cardiac function In-vitro Incubation Inflammatory response intensive care intensive care unit investigated Isolated LVEF membrane Microscopy mitigate Mortality no effect nuclear occur Patient patients pharmacological Precision RAT Result SARS-CoV-2 sensitivity serum severe ARDS Signaling significantly stem cell therapeutic potential veno-venous extracorporeal membrane oxygenation ventricular [DOI] 10.1371/journal.pone.0255976 PMC 바로가기 [Article Type] Research Article