COVID-19 vaccine development during pandemic: gap analysis, opportunities, and impact on future emerging infectious disease development strategies대유행 중 COVID-19 백신 개발: 격차 분석, 기회 및 미래의 신흥 전염병 개발 전략에 미치는 영향Article Published on 2021-04-032022-08-31 Journal: Human vaccines & immunotherapeutics [Category] MERS, SARS, 신약개발, [키워드] accelerated added addition addressed adjuvants Analysis COVID COVID-19 pandemic COVID-19 vaccine COVID-19 vaccine development Critical dosage dosage level effort Emerging infectious disease glassware GMP GMP manufacturing immune immune response Infectious disease Lipid nanoparticle Lipid nanoparticles long-lasting mRNA mRNA vaccine mRNA vaccines mRNA-lipid nanoparticle Neutralizing offer pandemic protective immune response provide regimen Safe stability Stress supply chains Vaccine Vaccine development vaccine dose Vaccines virus infectivity [DOI] 10.1080/21645515.2020.1822136 PMC 바로가기 [Article Type] Article
Antibody response to SARS-CoV-2 in infected patients with different clinical outcome임상 결과가 다른 감염된 환자의 SARS-CoV-2에 대한 항체 반응Article Published on 2021-04-012022-09-12 Journal: Journal of medical virology [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome analyzed antibody Antibody Response assays circulating Clinical outcome coronavirus Coronavirus-2 declining decrease evaluate Evidence humoral Humoral immunity IgG Immunity Immunoglobulin implication individuals induce infected patient infected with COVID-19 long-lasting neutralization neutralizing antibody Neutralizing antibody response occur outcome Patient pauci-symptomatic SARS-CoV-2 SARS-COV-2 infection screened serum antibody response severe disease Severe infection significant difference significantly higher subject two groups Vaccine [DOI] 10.1002/jmv.26789 PMC 바로가기 [Article Type] Article
Age-Related Dynamics of Lung-Resident Memory CD8 + T Cells in the Age of COVID-19COVID-19 시대의 폐 상주 기억 CD8 + T 세포의 연령 관련 역학Review Published on 2021-03-292022-09-11 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, [키워드] age aging process CD8 Cell Control coronavirus disease Coronavirus disease 2019 COVID-19 cross-reactive developmental Dynamics Epitopes heterogeneous response heterogeneous responses homeostasis homeostatic Immune status Immunity in viral Influenza Lineage Local long-lasting lung lung dysfunction pathogen Pathogens pathology patients Pneumonia portion Pulmonary pathology resident memory respiratory respiratory tract respiratory viral infection respiratory viral infections Symptom T cell T cell epitopes T cells Treatment Viral Viral pneumonia [DOI] 10.3389/fimmu.2021.636118 PMC 바로가기 [Article Type] Review
An Overview of Nanocarrier-Based Adjuvants for Vaccine DeliveryReview Published on 2021-03-272022-10-28 Journal: Pharmaceutics [Category] COVID-19, [키워드] adjuvant adjuvants Antigen contributing to delivery Disadvantages Diseases effective delivery immune response immunostimulatory inactivated induce Infection long-lasting memory response Nanocarriers Nanotechnology non-viral vectors parameter pathogen pattern recognition receptor phosphate PROTECT receptor receptors robust sustained toxin vaccination Vaccine vaccine delivery systems Vaccines vector viral vectors Virus-like particle whole organism [DOI] 10.3390/pharmaceutics13040455 PMC 바로가기 [Article Type] Review
Psychosocial impact of COVID-19 on cancer patients, survivors, and carers in Australia: a real-time assessment of cancer support servicesOriginal Article Published on 2021-03-112022-10-28 Journal: Supportive Care in Cancer [Category] COVID-19, [키워드] added affected analysed Analysis average Cancer cancer diagnosis Cancer patients cancer survivorship Care Consequences coronavirus coronavirus disease Council COVID-19 distress domain Healthcare provider information LINE long-lasting pandemic Patient patients peaked Psychological distress Psychosocial Psychosocial impact recommendation Result service supplementary material Support supportive care Survivors survivorship susceptibility virus [DOI] 10.1007/s00520-021-06101-3 PMC 바로가기 [Article Type] Original Article
Attributes and predictors of long COVID Research Published on 2021-03-102022-10-05 Journal: Nature Medicine [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome analyzed Anosmia attribute body mass index characteristic characterized coronavirus coronavirus disease Course COVID COVID-19 Dyspnea fatigue female FIVE headache identify increasing age independent individual Long long-lasting participant positive predict predictor Prevalence rehabilitation Replication report reported symptom rising risk risk factor Sex Symptom Symptoms the disease total sample size Treatment Trial [DOI] 10.1038/s41591-021-01292-y [Article Type] Research
Impact of a prolonged COVID-19 lockdown on patterns of admission, mortality and performance indicators in a cardiovascular intensive care unitObservational Study Published on 2021-03-032022-10-05 Journal: International journal for quality in health care : [Category] SARS, 임상, [키워드] Admission age Analysis antibiotics usage average Buenos Aires cardiovascular cardiovascular diseases cause concerning consecutive patient coronavirus disease COVID-19 COVID-19 pandemic critical condition cross-sectional discharge dropped Effect equity equity in health care Expenditure female patient Health health system highlight hospital Hospitalization Impact in-hospital mortality Intensive intensive care intensive care unit lockdown long-lasting Mortality occupancy rate pandemic Patient patient outcomes Prevalence Prevent protocol public health quality indicators reduction in retrospective risk study period [DOI] 10.1093/intqhc/mzab029 PMC 바로가기 [Article Type] Observational Study
Genetically Engineered Live-Attenuated Middle East Respiratory Syndrome Coronavirus Viruses Confer Full Protection against Lethal InfectionResearch Article Published on 2021-03-022022-10-29 Journal: mBio [Category] COVID-19, [키워드] acute respiratory syndrome approved attenuate attenuated vaccine C-terminal domain Cell culture coronavirus coronavirus SARS-CoV-2 Coronaviruses Deletion described dose E protein genetics genome engineering highly pathogenic immune responses immunization indicate induce Interaction killing knowledge lethal life-threatening long-lasting MERS-CoV Middle East mutant mutants passage Pathogenesis protection Protein provided Research respiratory respiratory syndrome coronavirus Safe SARS-CoV selected signaling pathway Vaccine vaccine candidate Vaccines virulence virulent virus virus replication [DOI] 10.1128/mBio.00103-21 PMC 바로가기 [Article Type] Research Article
Corona viruses: reaching far beyond the common coldArticles Published on 2021-03-012022-10-27 Journal: African Health Sciences [Category] Coronavirus, COVID-19, SARS, [키워드] acute respiratory distress acute respiratory syndrome Analysis cause Clinical features Cochrane Library common cold Corona coronavirus COVID-19 COVID-19 pandemic Diagnosis disease Epidemics Epidemiology etiology events example finding Frequency Genome gold standard Health Human Intervention invasive literature review long-lasting management mechanical ventilation MERS Middle East Mild MOST outbreak Pandemics patients Potential treatment prevalent Recombination recombination event Respiratory disease Respiratory illness scientist severe disease Severe infection severe respiratory disease strain Strains subsequent supportive care syndrome the SARS-CoV-2 virus undergo understanding upper respiratory infection Vaccine virulent virus viruses was performed worldwide pandemic [DOI] 10.4314/ahs.v21i1.27 PMC 바로가기 [Article Type] Articles
Corona viruses: reaching far beyond the common coldArticles Published on 2021-03-012022-10-27 Journal: African Health Sciences [Category] COVID-19, [키워드] acute respiratory distress acute respiratory syndrome Analysis cause Clinical features Cochrane Library common cold Corona coronavirus COVID-19 COVID-19 pandemic Diagnosis disease Epidemics Epidemiology etiology events example finding Frequency Genome gold standard Health Human Intervention invasive literature review long-lasting management mechanical ventilation MERS Middle East Mild MOST outbreak Pandemics patients Potential treatment prevalent Recombination recombination event Respiratory disease Respiratory illness scientist severe disease Severe infection severe respiratory disease strain Strains subsequent supportive care syndrome the SARS-CoV-2 virus undergo understanding upper respiratory infection Vaccine virulent virus viruses was performed worldwide pandemic [DOI] 10.4314/ahs.v21i1.27 PMC 바로가기 [Article Type] Articles