Case Series of COVID-19 Asymptomatic Newborns With Possible Intrapartum Transmission of SARS-CoV-2Pediatrics Published on 2020-09-292022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] age Analysis antibodies antibody Antibody detection Antibody testing Asymptomatic Case report collected Contamination COVID-19 COVID-19 infection detectable Efficacy exhibited IgM and IgG Infant Infection information intrapartum measure modify mother nasopharyngeal Nasopharyngeal swab negative RT-PCR Newborn observation pandemic positive positive RT-PCR Pregnancy pregnant pregnant women raise reaction Reactions reliability risk RT-PCR SARS-CoV-2 Sery Stool tested the patient Transmission vertical transmission [DOI] 10.3389/fped.2020.568979 PMC 바로가기 [Article Type] Pediatrics
The Impact of the COVID-19 Confinement on the Habits of PA Practice According to Gender (Male/Female): Spanish CaseArticle Published on 2020-09-232022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] ACSM Administered affecting age average cardiorespiratory caused change college COVID-19 COVID-19 pandemic drastic Gender genders habit Health Health authority highlight Impact intensity Medicine men men and women modify muscular neuromotor participated physical activity Practice Quality of life questionnaire reduce risk shifting significant decrease Spain Spanish sport statistically WHO women World Health Organization [DOI] 10.3390/ijerph17196961 PMC 바로가기 [Article Type] Article
Mobile Health Apps on COVID-19 Launched in the Early Days of the Pandemic: Content Analysis and ReviewOriginal Paper Published on 2020-09-162022-10-31 Journal: JMIR mHealth and uHealth [Category] COVID-19, [키워드] app assessment criteria automated Care conducted connection content content analysis coronavirus coronavirus disease country COVID-19 COVID-19 cases data entry Day dissemination evaluate feature function functions Google Play Health health authorities Health authority Health Education help helping identify IMPROVE inclusion criteria information knowledge mHealth Mobile mobile medical app modify MOST n=36 objective outcome outcomes performed professional Result review scored self-care Surveillance Symptom The United States was used [DOI] 10.2196/19796 PMC 바로가기 [Article Type] Original Paper
Analysis of the Influence of Psychological Contract on Employee Safety Behaviors against COVID-19Article Published on 2020-09-162022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] Affect Analysis Behavior Burnout China Chinese combating conscious COVID-19 double mediators employee Epidemic Factor hypothese influence job Job burnout measure mechanism modify perceived insider status Perspective positive prevention of COVID-19 Protective provided Psychological psychological contract questionnaire Questionnaires Safety safety behavior spread of COVID-19 tested was used weakened with COVID-19 [DOI] 10.3390/ijerph17186747 PMC 바로가기 [Article Type] Article
Time to adapt in the pandemic era: a prospective randomized non –inferiority study comparing time to intubate with and without the barrier box대유행 시대에 적응할 시간: 장벽 상자가 있는 경우와 없는 경우 삽관하는 시간을 비교한 전향적 무작위 비열등성 연구Research Article Published on 2020-09-142022-08-09 Journal: BMC Anesthesiology [Category] 임상, [키워드] 95% CI aerosol aerosol spread Aerosols Airway management in COVID patients airway management practices airway manipulation anesthesiologist anesthesiologists bag-mask ventilation Barrier box barrier boxe barrier boxes both groups clinically comparable confirmation COVID-19 disease defined determine Device disease elective surgeries end-tidal Endpoint enrolled full PPE’ full PPE’s glidescope group Hypothesis in both groups include Intubated intubation less limit loss of twitche loss of twitches lowest oxygen saturation Mean TTI modify Nerve stimulator non-inferiority controlled trial non-inferiority margin normal airway exam null hypothesis number of attempt oxygen oxygen saturation pandemic parameter Patient performed peripheral nerve peripheral nerve stimulator primary measured endpoint raise Randomized Randomly Registered rescue breaths Result secondary Secondary endpoints significant delay spread of COVID-19 study group t-test the mean the study group time time to intubate unpaired two-sample single-sided t-test Usage was used well-trained providers [DOI] 10.1186/s12871-020-01149-w PMC 바로가기 [Article Type] Research Article
Peptidyl Fluoromethyl Ketones and Their Applications in Medicinal ChemistryReview Published on 2020-09-032022-10-30 Journal: Molecules [Category] COVID-19, SARS, [키워드] application backbone can be used Cancer caspase cathepsin Chemistry Compound cysteine proteases disease Diseases enzymatic inhibitors Enzymes fluorinated peptides inhibit inhibitor insertion ketone modify pathogenic peptidyl fluoromethyl ketones physicochemical property probe protease Proteases proteolytic activity reactivity resulting SARS-CoV Mpro Serine serine proteases Treatment viral infections [DOI] 10.3390/molecules25174031 PMC 바로가기 [Article Type] Review
The Model for Early COvid-19 Recognition (MECOR) Score: A Proof-of-Concept for a Simple and Low-Cost Tool to Recognize a Possible Viral Etiology in Community-Acquired Pneumonia Patients during COVID-19 OutbreakArticle Published on 2020-08-212022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] addition affected AUROC blood cell count case-control study chest pain Cohort community-acquired pneumonia coronavirus cough COVID-19 COVID-19 patient cut-off Diagnosis diagnostic disease Dyspnea Effectiveness eosinophils evaluated examined excluded Fever immunosuppressants index Interstitial lung disease Lymphocytes Model modify Monocytes multivariate model nasopharyngeal swabs Neutrophils P -value parameter Patient patients treated peripheral blood cell Platelets Pneumonia Probability Prospective Study Recognition reduction in respiratory retrospective SARS-CoV-2 score selected sensitivity simple specificity Steroids Triage validation cohort White blood cell [DOI] 10.3390/diagnostics10090619 PMC 바로가기 [Article Type] Article
New Anti SARS-Cov-2 Targets for Quinoline Derivatives Chloroquine and Hydroxychloroquine †Article Published on 2020-08-142022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, [키워드] acute respiratory syndrome amino acid residues binding Chloroquine coronavirus demonstrated derivative docking examined HCQ Health Hydroxychloroquine identify Interaction maturation mechanism of action modify New performed polar Proofreading Protein SARS-CoV-2 Spread target Viral RNA virus [DOI] 10.3390/ijms21165856 PMC 바로가기 [Article Type] Article
Structure-Based Drug Design of an Inhibitor of the SARS-CoV-2 (COVID-19) Main Protease Using Free Software: A Tutorial for Students and Scientistspreprint Published on 2020-08-122022-10-31 Journal: ChemRxiv [Category] COVID-19, [키워드] AutoDock coronavirus COVID-19 disseminate drug drug candidate drug design experimental validation Free help homologous information inhibitor Interaction M pro modify molecular docking pandemic Pandemics peptide Peptide inhibitor protease provide SARS Coronavirus SARS-CoV SARS-CoV M SARS-CoV-2 scientist structure-based design structures student supplementary material the SARS-CoV-2 tutorial UCSF Chimera X-ray X-ray crystallographic structure [DOI] 10.26434/chemrxiv.12791954 PMC 바로가기 [Article Type] preprint
Ruxolitinib Rapidly Reduces Acute Respiratory Distress Syndrome in COVID-19 Disease. Analysis of Data Collection From RESPIRE ProtocolMedicine Published on 2020-08-042022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory distress administration Adverse ARDS case sery characterized clinical condition Clinical improvement clinical response clinical status clinically Collection complete recovery Course COVID-19 COVID19 Critically ill patient Cytokine storm syndrome death develop disease drug Evidence Evolution help Host hyperinflammation ICU identify immune-mediated diseases Infection inflammation response inhibitor JAK1 JAK2 Laboratory mechanical ventilation modify Mortality non-invasive ventilation organ function Oxygen requirement pandemic PaO Patient primary endpoint progressive COVID-19 progressive disease reduce Research respiratory Respiratory distress syndrome Respiratory function respiratory impairment ruxolitinib ruxolitinib treatment secondary endpoint Serious Adverse Event severe COVID-19 subsequent subset syndrome the disease therapeutic option treat Treatment ventilatory support viral-induced was recorded were assessed with COVID-19 [DOI] 10.3389/fmed.2020.00466 PMC 바로가기 [Article Type] Medicine