Label-Free Plasmonic Biosensor for Rapid, Quantitative, and Highly Sensitive COVID-19 Serology: Implementation and Clinical Validation신속하고 정량적이며 매우 민감한 Covid-19 혈청학을위한 라벨이없는 플라즈몬 바이오 센서 : 구현 및 임상 검증Article Published on 2021-12-312022-09-10 Journal: Analytical Chemistry [Category] Fulltext, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplification anti-SARS-CoV-2 antibody biosensor clinical clinical samples coronavirus COVID-19 COVID-19 pandemic Detection limit diagnostic diagnostic sensitivity diagnostics epidemiological Immunity Immunoglobulin immunological Laboratory management N protein negative sample offer peptide polyclonal antibodies positive quantification Rapid RBD respiratory SARS-CoV-2 sensitive sensitivity serological serological test Serological tests serology severe acute respiratory syndrome Coronavirus specificity Surveillance the disease Treatment vaccination validation with COVID-19 [DOI] 10.1021/acs.analchem.1c03850 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Aerosol Transmission Indoors: A Closer Look at Viral Load, Infectivity, the Effectiveness of Preventive Measures and a Simple Approach for Practical RecommendationsArticle Published on 2021-12-252022-10-30 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] addition adopted aerosol Airborne transmission approach attack rate calculate contribute COVID-19 individual Infection Infection prevention infection rate Infectivity joint lack less load mathematical measure outbreak parameter predict preventive measure preventive measures protective effect quantification required risk assessment model risk of infection SARS-CoV-2 simple simplified approaches Transmission Ventilation Viral load Volume wearing mask [DOI] 10.3390/ijerph19010220 PMC 바로가기 [Article Type] Article
Impairment of T cells’ antiviral and anti-inflammation immunities may be critical to death from COVID-19Mathematics Published on 2021-12-222022-10-28 Journal: Royal Society Open Science [Category] COVID-19, [키워드] age Anti-inflammation anti-inflammatory responses antibodies Antiviral antiviral response approach Clarifying Clinical data COVID-19 COVID-19 mortality Critical cytokine death dominant Factor functional heterogeneity immune immune response immune system Immunity Immunology and inflammation Inflammation lack males mathematical model mild patient Mortality non-survivor Non-survivors Patient provide quantification significantly Simulation suppressed survivor T cell tissue tissue repair Treatment Vaccine viral dynamics virus virus clearance yielding [DOI] 10.1098/rsos.211606 PMC 바로가기 [Article Type] Mathematics
Salivary Ferritin Changes in Patients with COVID-19COVID-19 환자의 타액 페리틴 변화Article Published on 2021-12-212022-09-10 Journal: International Journal of Environmental Research an [Category] 바이오마커, 치료기술, [키워드] addition assisted respiration Biomarker change changes in correction correlation COVID-19 COVID-19 patient COVID-19 patients COVID-19 test COVID-19 tests cytokine Cytokine storm diagnostic disease Effect evaluate evaluated ferritin ferritin levels healthy healthy control healthy controls highest inactivation increasingly individual Macrophage macrophage activation syndrome Mild nasal non-invasive sample not affect oxygen Patient patients with COVID-19 presenting Protein protocol quantification reported Respiration Saliva saliva samples SARS-CoV-2 treatment SDS serum Serum ferritin Serum level severe COVID-19 severe COVID-19 patients severity Significant total protein virus detection was measured were assessed with COVID-19 [DOI] 10.3390/ijerph19010041 PMC 바로가기 [Article Type] Article
COVID-19 wastewater surveillance in rural communities: Comparison of lagoon and pumping station samples농촌 지역 사회의 COVID-19 폐수 감시: 석호 및 펌프장 샘플 비교Article Published on 2021-12-202022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, 치료제, [키워드] applied Biomarkers Canada Chain Reaction changes in collected Community country COVID-19 downstream Epidemiology fecal granularity implementation incidence incidence of COVID-19 integrity knowledge lagoon limit Mild N1 and N2 pathogen Pathogens Pepper mild mottle virus polymerase chain polymerase chain reaction Prevalence prevalence of COVID-19 pumping station quantification Quantitative Region RNA concentration RNA concentrations RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 surveillance SARS-CoV-2 viral stability Surveillance Topic Treatment upstream viral signal wastewater wastewater surveillance Wastewater treatment lagoon Wastewater-based epidemiology [DOI] 10.1016/j.scitotenv.2021.149618 PMC 바로가기 [Article Type] Article
Performance evaluation of virus concentration methods for implementing SARS-CoV-2 wastewater based epidemiology emphasizing quick data turnaround신속한 데이터 처리를 강조하는 SARS-CoV-2 폐수 기반 역학 구현을 위한 바이러스 농도 방법의 성능 평가Article Published on 2021-12-202022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, [키워드] Analysis centrifugation Community Concentration conjunction COVID-19 COVID-19 case COVID-19 cases decrease detect Electronegative Membrane Filtration Epidemiology evaluated filtration HA Method Increased InnovaPrep CP Select living environment lysis buffer membrane MONITOR observation outbreak performance pipette positive predict produced protocol public health quantification Result RT-qPCR Sample SARS-CoV-2 sensitivity sonication Spread Surveillance tested threshold trajectory Treatment universities virus virus concentration wastewater Wastewater based epidemiology (WBE) [DOI] 10.1016/j.scitotenv.2021.149656 PMC 바로가기 [Article Type] Article
Immune Response to BNT162b2 in Solid Organ Transplant Recipients: Negative Impact of Mycophenolate and High Responsiveness of SARS-CoV-2 Recovered Subjects against Delta VariantArticle Published on 2021-12-182022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] acute respiratory syndrome baseline BNT162b2 BNT162b2 vaccine cell-mediated response Cohort Complete Control Delta dose elicited evaluated ex-vivo ELISpot healthy subjects humoral Humoral response immune response Immunocompromised patient Impact impairment Italy median mRNA vaccine mycophenolate naïve negative observation of BNT162b2 patients positive quantification recipient recovered response responsiveness Result SARS-CoV-2 SARS-CoV-2 neutralizing antibody Seroconversion significantly lower Solid solid organ transplant Solid organ transplant recipients subject subset Support T-cell Response the SARS-CoV-2 Transplant uninfected vaccination vaccination schedule Vaccine variant virus was performed [DOI] 10.3390/microorganisms9122622 PMC 바로가기 [Article Type] Article
Establishment of a quantitative RT-PCR detection of SARS-CoV-2 virusSARS-CoV-2 바이러스 정량적 RT-PCR 검출 확립Research Published on 2021-12-172022-09-10 Journal: European Journal of Medical Research [Category] SARS, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antiviral drug antiviral drugs calculated coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 virus Dilution division E gene E-gene Efficacy evaluated International limit limit of detection LLOQ Novel coronavirus novel coronavirus disease nucleocapsid outbreak provided public health emergency quantification Quantitative RdRP respiratory Result RNA RNA-dependent RNA polymerase Roche Diagnostics RT-PCR RT-PCR detection RT-PCR kit RT-PCR kits SARS-CoV-2 SARS-CoV-2 virus severe acute respiratory syndrome Coronavirus standard curve supplementary material Vaccine Viral Viral load viral loads virus [DOI] 10.1186/s40001-021-00608-5 PMC 바로가기 [Article Type] Research
Potential SARS-CoV-2 infectiousness among asymptomatic healthcare workersResearch Article Published on 2021-12-172022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] Administered Asymptomatic Cohort cohort study database disease Epidemic group had no HCW HCWs healthcare worker Infection majority performed Potential pre-symptomatic quantification questionnaire SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RT-PCR serology sick subject subjects symptomatic symptomatic disease the SARS-CoV-2 transmitted unique [DOI] 10.1371/journal.pone.0260453 PMC 바로가기 [Article Type] Research Article
Superspreading quantified from bursty epidemic trajectoriesArticle Published on 2021-12-162022-10-29 Journal: Scientific Reports [Category] Coronavirus, SARS, [키워드] 95% confidence interval Affect Applied mathematics basic reproduction number Community Computational biophysics COVID-19 COVID-19 epidemic Denmark Diseases Epidemic heterogeneity infections mitigating strategy overdispersion factor Population dynamics quantification quantified Statistics trajectory Variation [DOI] 10.1038/s41598-021-03126-w PMC 바로가기 [Article Type] Article