Lack of association between vitamin D insufficiency and clinical outcomes of patients with COVID-19 infectionResearch Published on 2021-05-182022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] adverse outcome analyzed association chronic Clinical outcome coronavirus COVID-19 COVID-19 infection COVID-19 patient cross-sectional cutoff point determine disorder duration of hospitalization greater Hospitalization infected with COVID-19 Infection Infectious disease insufficiency Iran Laboratory less lower risk multivariable outcome Patient patients with COVID-19 Protective protective effect Result SARS-CoV-2 Severity of infection statistically significant suffered Sufficiency the patient underlying disease Vitamin D vitamin D insufficiency vitamin D level vitamin D sufficiency was used [DOI] 10.1186/s12879-021-06168-7 PMC 바로가기 [Article Type] Research
COVID-19 in People With Schizophrenia: Potential Mechanisms Linking Schizophrenia to Poor PrognosisPsychiatry Published on 2021-05-172022-10-31 Journal: Frontiers in Psychiatry [Category] COVID-19, [키워드] adverse outcome age cardiometabolic Comorbidity COVID-19 COVID-19 in patient disease severity effective Evidence first episode psychosis greater independent indicate knowledge mechanisms Mortality outcome pathophysiological mechanism patients with COVID-19 Poor Potential potential mechanism Psychosis renal required Respiratory disease risk risk factor robust SARS-CoV-2 Schizophrenia Severe mental illness susceptibility treatment strategy [DOI] 10.3389/fpsyt.2021.666067 PMC 바로가기 [Article Type] Psychiatry
COVID-19 and the liver: an adverse outcome pathway perspectiveCOVID-19와 간: 불리한 결과 경로 관점Review Published on 2021-05-152022-09-11 Journal: Toxicology [Category] SARS, 치료제, [키워드] adverse outcome anticipated AOP binding caused COVID-19 COVID-19 patients hospitalized COVID-19 patient hospitalized COVID-19 patients hypoxia knowledge liver Liver damage Liver injury Local mechanism pathway Pathways Perspective pharmacological treatment Research SARS-CoV-2 systemic inflammation Therapies Vaccine virus [DOI] 10.1016/j.tox.2021.152765 PMC 바로가기 [Article Type] Review
Clinical course and risk factors of fatal adverse outcomes in COVID-19 patients in Korea: a nationwide retrospective cohort studyArticle Published on 2021-05-122022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] 95% CI 95% confidence interval Admission adverse outcome adverse outcomes age association clinical Clinical characteristics Clinical data Clinical outcome clinician Control coronavirus disease Course COVID-19 COVID-19 patient Cox proportional hazard database death Dementia diabetes discharged patient Dyspnoea epidemiological Epidemiology hazard ratio help ICU ICU admission identify Increased intensive care investigated Isolation Logistic regression analysis malignancy Mortality multivariable non-survivor occurred Odds ratio Patient poor prognosis predicted Presence prevention regression equation retrospective cohort study risk factor Risk factors survivor variable with COVID-19 [DOI] 10.1038/s41598-021-89548-y PMC 바로가기 [Article Type] Article
Serum Uric Acid Concentrations and Risk of Adverse Outcomes in Patients With COVID-19Endocrinology Published on 2021-05-062022-10-31 Journal: Frontiers in Endocrinology [Category] COVID-19, MERS, [키워드] 95% CI 95% confidence interval acid acute respiratory syndrome Admission admitted to ICU Adverse adverse outcome adverse outcomes affected age Analysis analyzed association baseline components Concentration COVID-19 COVID-19 patient cubic spline death determine died events Hospitalization hospitalized patient Hyperuricemia Hypouricemia ICU ICU admission In-hospital increased risk intensive care laboratory-confirmed mechanical ventilation Mortality Odds ratio outcome Patient previous study Primary outcome produced reached regression analysis relationship respiratory diseases Result risk serum Serum level severe coronavirus disease study cohort U-shape uric acid was performed was used women [DOI] 10.3389/fendo.2021.633767 PMC 바로가기 [Article Type] Endocrinology
Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre studyAcademicSubjects/MED00280 Published on 2021-05-052022-10-28 Journal: Age and Ageing [Category] COVID-19, SARS, [키워드] adverse outcome age Analysis Cancer cardiovascular disease Care CFS clinical co-morbidities cohort study collected data confidence interval coronavirus disease country COVID-19 COVID-19 mortality Cox regression analysis delirium Dementia demonstrated diagnose discharge disease frailty hazard ratio hospital hospitalised Illness severity Increased increased risk increasing age Inflammation International interquartile range involved likelihood male median age mental health Mortality Odds ratio Older Older age ordinal logistic regression Patient renal Result risk risk of death scale Sex survivor transitions of care variables with COVID-19 [DOI] 10.1093/ageing/afab026 PMC 바로가기 [Article Type] AcademicSubjects/MED00280
Circulating activated neutrophils in COVID-19: An independent predictor for mechanical ventilation and deathCOVID-19의 순환 활성화 호중구: 기계적 환기 및 사망에 대한 독립적인 예측인자Article Published on 2021-05-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 바이오마커, 치료기술, [키워드] Aberrant neutrophil response activated neutrophil Activated neutrophils adverse outcome age analyzed Biomarker Blood Clinical outcome clinical risk factor COVID-19 Critical illness cut-off value death diabete diabetes exacerbated fluorescence intensity Host immune response hypertension hypoxia IL-6 Immunity independent Inflammation Innate Innate immunity interleukin interleukin-6 mechanical ventilation neutrophil neutrophil activation neutrophil response Neutrophils obesity opens Patient predict predictor quantum Ratio Retrospective study sensitivity Significant specificity Support Therapeutic strategies tissue Viral viral replication [DOI] 10.1016/j.ijid.2021.03.066 PMC 바로가기 [Article Type] Article
Liver fibrosis in patients with metabolic associated fatty liver disease is a risk factor for adverse outcomes in COVID-19대사 관련 지방간 질환 환자의 간 섬유증은 COVID-19의 불리한 결과에 대한 위험 요소입니다Article Published on 2021-05-012022-09-11 Journal: Digestive and liver disease : official journal of [Category] 바이오마커, [키워드] Acute kidney injury adverse outcome AKI analyzed association AST cohort study Computed tomography computed tomography scan coronavirus coronavirus disease COVID-19 COVID-19 patients Cox regression analysis CT scan determined by disease evaluate Fatty liver fatty liver disease fibrosis Hospital admission hospitalized patient hospitalized patients incidence increased risk inflammatory markers Kaplan-Meier Kaplan-Meier curve Kaplan-Meier curves liver Liver fibrosis liver steatosis Logistic regression analysis Mann-Whitney U mechanical ventilation metabolic Metabolic diseases metabolic dysfunction Mortality NAFLD no differences onset of symptom Patient patients with COVID-19 Platelet Prognosis pulmonary involvement retrospective cohort study risk factor Risk factors SARS-CoV-2 severe coronavirus disease severity scores steatosis t-test Treatment was determined were used with COVID-19 [DOI] 10.1016/j.dld.2021.01.019 PMC 바로가기 [Article Type] Article
Heart failure outcomes and Covid-19Research article Published on 2021-05-012022-10-05 Journal: Diabetes research and clinical practice [Category] SARS, 바이오마커, [키워드] acute illness acute respiratory syndrome addition adverse outcome Biomarker Cardiac pathology Comorbidity coronavirus coronavirus disease COVID-19 COVID-19 pandemic COVID-19 patient diagnosed diastolic dysfunction echocardiographic endothelial heart heart failure high risk increased mortality Infection Injury LV systolic dysfunction magnetic resonance imaging Mortality MRI myocardial injury observation outcome Patient patients with COVID-19 Post-COVID-19 cardiac injury presenting prognostic SARS-CoV-2 sick the SARS-CoV-2 treated vaccination ventricular widespread with COVID-19 [DOI] 10.1016/j.diabres.2021.108794 [Article Type] Research article
Association between iron status and the risk of adverse outcomes in COVID-19Research article Published on 2021-05-012022-10-05 Journal: Clinical nutrition (Edinburgh, Scotland) [Category] SARS, 바이오마커, [키워드] Acute cardiac injury Acute kidney injury Acute liver injury adjusted adverse outcome age ARDS association Biomarker Clinical outcome Coagulopathy collected Comorbidities concentrations conditions COVID-19 COVID-19 patient COVID-19 patients COVID-19 prognosis cytokine Cytokine storm defend demographic ferritin Hospital stay Host IL-6 infective Injury interleukin-6 interquartile range iron Laboratory median age metabolism Multiple–organ injury organism parameter Poisson regression Prognosis Result retrospective cohort study risk risk factor serum Severe case severity severity of COVID-19 Sex suffered the median Tongji Hospital Transferrin viral proliferation was used while Wuhan, China [DOI] 10.1016/j.clnu.2020.11.033 [Article Type] Research article