Early-pandemic wastewater surveillance of SARS-CoV-2 in Southern Nevada: Methodology, occurrence, and incidence/prevalence considerationsFull Paper Published on 2020-12-312022-10-28 Journal: Water Research X [Category] COVID-19, [키워드] Abstract appear approach Community comparability Composite Concentration concentrations conditions COVID-19 detect detection driven by early phase Effect epidemiological exhibited fecal genetic marker genetic material global pandemic highlighting Image incidence increase in infected individuals measure methodological Mild mitigate multiple study Numerous Occurrence pandemic Prevalence public health quantification ranged reported responsible SARS-CoV-2 SARS-CoV-2 RNA secondary sensitivity sewage Surveillance surveillance data Variability virus Volume wastewater surveillance WHO World Health Organization [DOI] 10.1016/j.wroa.2020.100086 PMC 바로가기 [Article Type] Full Paper
Fluoroquinolone Antibiotics Exhibit Low Antiviral Activity against SARS-CoV-2 and MERS-CoVFluoroquinolone 항생제는 SARS-CoV-2 및 MERS-CoV에 대해 낮은 항바이러스 활성을 나타냅니다.Article Published on 2020-12-232022-09-10 Journal: Viruses [Category] MERS, SARS, 신약개발, 치료기술, 치료제, [키워드] (enoxacin A549 A549 cell A549 cells ACE2 activity Antiviral antiviral therapies caused Cell cell type cell types cellular ciprofloxacin Concentration concentrations Coronaviruses COVID-19 cultured cell cultured cells effective Efficacy enoxacin entry receptor FDA-approved drug FDA-approved drugs fluoroquinolones levofloxacin lowest MERS MERS-CoV moxifloxacin overexpress potency Replication repurposing respiratory respiratory infection respiratory infections SARS-CoV-2 SARS-CoV-2 entry receptor SARS-CoV-2 replication suppress suppressed the SARS-CoV-2 Toxicity treat Treatment Vero Cell Vero cells were assessed [DOI] 10.3390/v13010008 PMC 바로가기 [Article Type] Article
Assessment of the potential role of atmospheric particulate pollution and airborne transmission in intensifying the first wave pandemic impact of SARS-CoV-2/COVID-19 in Northern ItalyResearch Article Published on 2020-12-212022-10-28 Journal: Bulletin of Atmospheric Science and Technology [Category] COVID-19, [키워드] activate Activation acute respiratory syndrome addition Airborne virus transmission amplifying assessment atmospheric average carried China collected Combination Concentration concentrations consequence contagious coronavirus correlated correlation coefficient COVID-19 COVID-19 infection death dose doubling Effect effective enhanced Environmental pollution Epidemiologic parameters exceeded Factor Fatality rate First wave humans incidence indicated infected individual infected patient Infection infection rate infective Italian Italy mortality rate Northern region occurred pandemic Particle Particles pathology PM10 PM2.5 Region reported Respiratory system SARS-CoV-2 Spread statistical analysis Statistics Transmission transported Valley virus virus carrier while WHO Wuhan [DOI] 10.1007/s42865-020-00024-3 PMC 바로가기 [Article Type] Research Article
Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid게놈 RNA 요소가 SARS-CoV-2 뉴클레오캡시드의 상 분리를 유도합니다Article Published on 2020-12-172022-09-11 Journal: Molecular Cell [Category] SARS, 신약개발, 치료법, 치료제, [키워드] aggregation Antiviral compound Antiviral compounds binding site body temperature buffer characterized concentrations condensation condition coronavirus crosslink drive effective element feature Genome genomic genomic region human body liquid location mammalian cell mammalian cells N-protein nucleocapsid nucleocapsid protein phase physiological promote reduced Region regulate RNA RNA sequence room temperature SARS-CoV-2 SARS-CoV-2, Condensation, phase separation, packaging, RNP-MaP, RNA structure, nucleocapsid, coronavirus. separation single-stranded Small molecules strength temperature the SARS-CoV-2 valency Viral Viral RNA [DOI] 10.1016/j.molcel.2020.11.041 PMC 바로가기 [Article Type] Article
Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection인간 가용성 ACE2는 SARS-CoV-2 감염에서 렘데시비르의 효과를 향상시킵니다Report Published on 2020-12-142022-09-11 Journal: EMBO Molecular Medicine [Category] SARS, 치료제, [키워드] ACE2 additive effect additive effects adenylate kinase antiviral drug antiviral drugs approach authorization Cell cell entry cell surface receptor cells clinical trial clinical trials combination therapy combination treatment concentrations COVID‐19 COVID‐19 Critical decrease dose Effect effective drug Efficiency highlighting HIV treatment Human human kidney IMPROVE infections investigated kidney kidney organoids kinase life life cycle Microbiology, Virology & Host Pathogen Interaction Mortality open outcome pathway provided receptor ACE2 reduce regimen Remdesivir Replication required Safe SARS‐CoV‐2 SARS‐CoV‐2 infection shown singular soluble ACE2 surface receptor targets therapeutic therapeutic window Toxicity Treatment Vero E6 Viral Viral load Viral RNA was used [DOI] 10.15252/emmm.202013426 PMC 바로가기 [Article Type] Report
Thyroid Hormone Changes in Early Pregnancy Along With the COVID-19 PandemicEndocrinology Published on 2020-12-072022-10-31 Journal: Frontiers in Endocrinology [Category] COVID-19, MERS, [키워드] abnormality Affect analyses antibody Anxiety association baseline characteristics change changes in China Cohort Concentration concentrations COVID-19 COVID-19 outbreak COVID-19 pandemic Depression determine develop disease early pregnancy eligible fetal group hormone Hormones increased risk induce Level outcomes pandemic Patient peroxidase Pregnancy pregnant pregnant women propensity score matching reported Result risk Shanghai significantly significantly higher significantly lower Thyroid thyrotropin thyroxine TPO Treatment triiodothyronine TSH two group women [DOI] 10.3389/fendo.2020.606723 PMC 바로가기 [Article Type] Endocrinology
Determinants of soluble angiotensin-converting enzyme 2 concentrations in adult patients with complex congenital heart diseaseOriginal Paper Published on 2020-12-052022-10-31 Journal: Clinical Research in Cardiology [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Abstract ACE ACE inhibitor ACE2 angiotensin receptor blocker angiotensin-converting enzyme 2 antagonist ARB cardiovascular disorder CHD complex Complex congenital heart disease Concentration concentrations Corporation COVID-19 creatinine determinant disease echocardiographic parameters elevated enzyme functional healthy control healthy controls heart failure highest Human Laboratory Linear regression analysis Morphological multivariable model pandemic Patient receptor Result sACE2 SARS-CoV-2 serum significantly significantly increased soluble ACE2 univariable were measured [DOI] 10.1007/s00392-020-01782-y PMC 바로가기 [Article Type] Original Paper
Association between the New COVID-19 Cases and Air Pollution with Meteorological Elements in Nine Counties of New York StateArticle Published on 2020-12-042022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] association atmospheric Bayesian collected component Concentration concentrations conditions contribute covariate COVID-19 detect Electronic health record element highest include infected case infected cases INLA linear mixed model meteorological element New New York nine O3 PM2.5 Pollution predicted real-world data Record Registered RWD state with COVID-19 [DOI] 10.3390/ijerph17239055 PMC 바로가기 [Article Type] Article
The Benefits of Vitamin D Supplementation for Athletes: Better Performance and Reduced Risk of COVID-19Review Published on 2020-12-042022-10-31 Journal: Nutrients [Category] COVID-19, MERS, SARS, [키워드] “cytokine storm” 25-hydroxyvitamin D Acute respiratory tract infections angiotensin-converting enzyme 2 athletic Athletic performance Better clinical Concentration concentrations consequence Consequences correlated COVID-19 COVID-19 pandemic death disrupting Effect epithelial event Hypothesis Immunity IMPROVE incidence increase Infection Inflammation Lungs mechanism observational study performance Proinflammatory cytokine raise reduce reducing Replication Respiratory tract infections risk risk of COVID-19 serum serum 25-hydroxyvitamin D severity severity of COVID-19 shown survival team sports the SARS-CoV-2 the United State Trial Vascular virus Vitamin D Vitamin D supplementation [DOI] 10.3390/nu12123741 PMC 바로가기 [Article Type] Review
Effects of Ozone Treatment on Personal Protective Equipment Contaminated with SARS-CoV-2Article Published on 2020-12-032022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] acute respiratory syndrome amplification component concentrations conditions Contaminated Contamination coronavirus COVID-19 decontamination dependent on Effect Effects eliminated Health Healthcare professional heat-inactivated hospital implication increased risk management modify oxidative stress ozone treatment Personal protective equipment polymerase chain PPE PPM problem reactive oxygen species Research risk SARS-CoV-2 SARS-CoV-2 strain Stress treated Treatment [DOI] 10.3390/antiox9121222 PMC 바로가기 [Article Type] Article