The Light and Shadow of Rapid Serological Tests for SARS-CoV-2 Infection: Results from a Study in a Large Emergency DepartmentArticle Published on 2020-09-072022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgM circulation clinical setting consecutive patient COVID-19 Critical Department diagnosis of SARS-CoV-2 Emergency evaluated greatest number identify IgG Infection Laboratory test LIGHT management Negative predictive value pandemic Patient positive Prevalence public health measures Rapid Real-time PCR real-time PCR assay reported respiratory symptom respiratory symptoms Result Sample SARS-CoV-2 SARS-COV-2 infection sensitivity Serological assay serological test shadow significantly higher specificity Test tested the SARS-CoV-2 virus [DOI] 10.3390/ijerph17186493 PMC 바로가기 [Article Type] Article
Sensitivity, Specificity and Predictive Values of Molecular and Serological Tests for COVID-19: A Longitudinal Study in Emergency RoomArticle Published on 2020-09-032022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Accuracy class clinical re-assessment Diagnosis diagnosis of SARS-CoV-2 ELISA Emergency enrolled evaluated Final FIVE highest IgM Infection Latent longitudinal lowest molecular molecular test Negative predictive value NPV Patient PCR positive PPV ranged Rapid diagnostic test RdRP RDT room RT-PCR RT-PCRs SARS-CoV-2 SARS-COV-2 infection sensitivity serological test serology significant difference single gene specificity targets Test utility value was performed [DOI] 10.3390/diagnostics10090669 PMC 바로가기 [Article Type] Article
Schrödinger’s Worker: Are They Positive or Negative for SARS-CoV-2?Viewpoint Published on 2020-08-312022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] COVID-19 diagnosis of SARS-CoV-2 diagnostic test Health Infection limit negative occupational health Physicians Predictive Value of Tests public health Reverse transcriptase polymerase chain reaction SARS-CoV-2 Sensitivity and specificity serologic tests subject Surveillance tested [DOI] 10.3390/ijerph17176316 PMC 바로가기 [Article Type] Viewpoint
A Decision Aide for the Risk Stratification of GU Cancer Patients at Risk of SARS-CoV-2 Infection, COVID-19 Related Hospitalization, Intubation, and MortalityArticle Published on 2020-08-302022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] AUC benefit blood pressure BMI cancer patient Cancer patients cause clinical variable co-morbidities Combination COVID-19 COVID-19-related death database death decision decision curve analysis demographic develop Diagnosis diagnosis of SARS-CoV-2 genito-urinary cancer Hospitalization identify intubation malignancy management morbidity and mortality Mortality Mount Sinai oxygen saturation Patient positive predict provided respiratory rate retrospective risk risk calculator risk of death SARS-CoV-2 SARS-CoV-2 test screened syndrome System temperature tested threshold urologic oncology [DOI] 10.3390/jcm9092799 PMC 바로가기 [Article Type] Article
High dose dexamethasone treatment for Acute Respiratory Distress Syndrome secondary to COVID-19: a structured summary of a study protocol for a randomised controlled trialCOVID-19에 따른 급성 호흡곤란 증후군에 대한 고용량 덱사메타손 치료: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-08-262022-08-13 Journal: Trials [Category] MERS, 임상, [키워드] 1:1 active cancer acute respiratory distress acute respiratory distress syndrome Adult patients advance directives Advanced cancer age alpha error anticipated approved ARDS assessment assigned bilateral pulmonary infiltrates Blinding block breast-feeding Buenos Aires capture cardiac disease CEMIC clinical clinical trial code Complete concealed Confirmed COVID-19 COVID-19, Dexamethasone, Acute Respiratory Distress Syndrome, Randomised controlled trial, protocol, Steroids delirium develop Dexamethasone diagnosis of SARS-CoV-2 directive discharge disease dissemination do not resuscitate dose Effectiveness element End-Expiratory Pressure evaluate exclusion criteria Expiratory Pressure explained failure followed by Frequency glucocorticoid Glucocorticoids group hemodynamic High dose HIV infection hypoxemic Hypoxemic respiratory failure ICU Immunosuppression Immunosuppressive agents include inclusion criteria Infection Informed consent intensive care unit International legal guardian Length less Life expectancy local Ethics Committee mechanical ventilation Mortality multicenter muscle weakness Nosocomial infection Nosocomial infections number objective open open label open trial other disease other diseases outcome Palliative care PaO parallel group participant Participation Patient Patient care platform Pneumonia Positive end-expiratory pressure power power of 80% Prednisone pressure Prone position protocol R language random randomised randomised controlled trial randomization Randomized randomized clinical trial receive recruitment Registered renal renal disease respiratory respiratory distress Respiratory distress syndrome Respiratory failure resuscitate order RT-PCR Sample size SARS-COV-2 infection SARS-CoV-2 pneumonia secondary Secondary outcomes secondary to sequence Sequential Organ Failure Assessment severe immunosuppression SOFA Standard deviation status Stratified randomization Study protocol subject Support syndrome table terminal Terminal disease title Treatment treatment groups Trial Trial registration two-tailed alpha error Variation ventilator ventilator-free day Ventilator-free days ventilatory Version viral shedding weakness website women [DOI] 10.1186/s13063-020-04646-y PMC 바로가기 [Article Type] Letter
Investigation of compatibility of severe acute respiratory syndrome coronavirus 2 reverse transcriptase-PCR kits containing different gene targets during coronavirus disease 2019 pandemicResearch Article Published on 2020-08-262022-10-31 Journal: Future Virology [Category] COVID-19, [키워드] acute respiratory syndrome added amplification amplification curve analyses Biomarker coronavirus coronavirus disease correlation COVID-19 Diagnosis diagnosis of SARS-CoV-2 evaluated gene target Genes high correlation investigation material pandemic Patient PCR RdRp gene regression analysis RT-PCR Sample SARS-CoV-2 SARS-CoV-2 RT-PCR single gene tested while [DOI] 10.2217/fvl-2020-0169 PMC 바로가기 [Article Type] Research Article
Macrophage activation syndrome as an unusual presentation of paucisymptomatic severe acute respiratory syndrome coronavirus 2 infection A case report4900 Published on 2020-08-072022-10-30 Journal: Medicine [Category] COVID-19, MERS, [키워드] Activation acute respiratory syndrome anti-SARS-CoV-2 Case report characterized clinical complications coronavirus coronavirus disease criteria cytokine profile develop Diagnosis diagnosis of SARS-CoV-2 empiric antibiotic Follow-up Hydroxychloroquine hyper-inflammation Immunoglobulin immunoglobulin A independent Infection interleukin-6 life-threatening macrophages Multiorgan dysfunction Nasopharyngeal swab Patient polymerase chain positive reverse transcription SARS-CoV-2 SARS-COV-2 infection serum syndrome the patient tissue injury treated unique [DOI] 10.1097/MD.0000000000021570 PMC 바로가기 [Article Type] 4900
Clinical and Imaging Characteristics in Patients with SARS-CoV-2 Infection and Acute Intracranial HemorrhageArticle Published on 2020-08-062022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute respiratory syndrome Admission analyzed bleeding Brain Care case sery characteristics of patient characterized clinical Cohort collected Computed tomography consecutive patient coronavirus Course COVID-19 COVID-19 diagnosis COVID-19 infection COVID-19 patient diagnosed diagnosed with COVID-19 diagnosis of COVID-19 diagnosis of SARS-CoV-2 European European country Evidence FIVE hemorrhage hotspot imaging imaging characteristics Infection Intracranial intracranial hemorrhage intraventricular IQR Isolated Laboratory laboratory-confirmed multicenter occur outcome parenchymal pathologic pathophysiological feature Patient predominant presenting radiologic retrospective SARS-CoV-2 severe COVID-19 subarachnoid hemorrhage therapy with COVID-19 [DOI] 10.3390/jcm9082543 PMC 바로가기 [Article Type] Article
Value of Viral Nucleic Acid in Sputum and Feces and Specific IgM/IgG in Serum for the Diagnosis of Coronavirus Disease 2019Cellular and Infection Microbiology Published on 2020-08-062022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] acid acute respiratory syndrome analyzed Antibody test assist caused China clinical sample collected convalescent patient coronavirus COVID-19 COVID-19 patients COVID-19-related symptom Critical detectable detection rate diagnosed diagnosis of SARS-CoV-2 discharge disease Fece feces Guangzhou hospital IgG IgM IgM/IgG IMPROVE Infection measure multiple pathway nucleic acid test Patient patients with SARS-CoV-2 Pneumonia Prevent quarantine SARS-CoV-2 SARS-COV-2 infection serological test Specific specimens Spread sputum Transmission university value viral nucleic acid viral shedding with COVID-19 Wuhan [DOI] 10.3389/fcimb.2020.00445 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Pooled RNA sample reverse transcriptase real time PCR assay for SARS CoV-2 infection: A reliable, faster and economical methodSARS CoV-2 감염에 대한 풀링된 RNA 샘플 역전사효소 실시간 PCR 분석: 신뢰할 수 있고 빠르고 경제적인 방법Research Article Published on 2020-07-302022-08-13 Journal: PLoS ONE [Category] MERS, SARS, 유전자 메커니즘, [키워드] chain China Cluster Corona virus country COVID-19 Ct value demonstrated detect diagnosis of COVID-19 diagnosis of SARS-CoV-2 diagnostic capabilities disease E gene evaluate expand Extracted faster help hour Infection not affected novel objective pandemic PCR PCR assay Pneumonia pneumonia case pneumonia cases pool pooling positive sample protocol Randomly reagent reagents real time reduce Result RNA RNA sample RNA samples RT-qPCR SARS CoV SARS CoV-2 SARS-COV-2 infection Study design transcriptase Transmission virus Virus Disease Wuhan [DOI] 10.1371/journal.pone.0236859 PMC 바로가기 [Article Type] Research Article