Messenger RNA – Page 22 – Communicable Diseases Research

Prevention and Attenuation of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines

Article

Published on 2021-07-222022-10-04
Journal: The New England Journal of Medicine [Category] MERS, SARS, 진단, 치료기술,

Poor humoral and T-cell response to two-dose SARS-CoV-2 messenger RNA vaccine BNT162b2 in cardiothoracic transplant recipients

흉부 이식 수혜자의 2회 용량 SARS-CoV-2 메신저 RNA 백신 BNT162b2에 대한 체액 및 T 세포 반응 불량

Original Paper

Published on 2021-07-092022-09-11
Journal: Clinical Research in Cardiology [Category] MERS, 진단, 치료법,

[키워드] Abbott age analysed anti-SARS-CoV-2 average BioNTech/Pfizer (BNT162b2) vaccine blood sample Blood samples BNT162b2 BNT162b2 vaccine booster dose cellular response control group COVID-19 infection detectable domain domains dose ELISA Euroimmun Evidence evidence of excluded exhibited functional Genscript healthy heart humoral IgG immune response immune responses immunoassays Immunocompromised patient Immunocompromised patients immunogenicity Immunoglobulin infectious agent infectious agents inhibitory interferon interferon-γ lung majority membrane protein Messenger RNA Neutralizing antibodies neutralizing antibody nucleocapsid Organ transplant Patient patients peptides Pfizer-BioNTech Poor prime Qiagen QuantiFERON recipient recipients robust SARS-CoV-2 Seroconversion shown significant increase Specific T-cell response Spike protein stimulated T-cell T-cell Response tested titre Transplant recipients vaccination Vaccine Vaccines Viral viral spike was measured Whole blood
[DOI] 10.1007/s00392-021-01880-5 PMC 바로가기 [Article Type] Original Paper

Evaluation of Messenger RNA From COVID-19 BTN162b2 and mRNA-1273 Vaccines in Human Milk

Research

Published on 2021-07-062022-10-31
Journal: JAMA Pediatrics [Category] COVID-19, MERS, SARS,

[키워드] cohort study COVID-19 detectable determine Human human milk lactating messenger Messenger RNA milk mother mRNA-1273 RNA vaccination
[DOI] 10.1001/jamapediatrics.2021.1929 PMC 바로가기 [Article Type] Research

Characterization of a new SARS-CoV-2 variant that emerged in Brazil

브라질에서 출현한 새로운 SARS-CoV-2 변종 특성 규명

Comparative Study

Published on 2021-07-062022-09-10
Journal: Proceedings of the National Academy of Sciences of [Category] SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition animal model Antigen aspartic acid BNT162b2 Brazil characterization characterized circulating comparable convalescent human plasma convalescent patient Convalescent patients convalescent sera coronavirus COVID-19 deaths glycine hamster hamsters Host host range in viral Infection Japan less Lower respiratory tract Messenger RNA mice multiple mutation multiple mutations neutralization titer Neutralizing antibodies neutralizing antibody new SARS-CoV-2 number of deaths P.1 P.1 variant P.1 variants passive transfer pathogenicity Patient plasma position prevented protective immune response Protein reduced Reinfection Replication replicative respiratory S protein SARS-CoV-2 SARS-CoV-2 disease SARS-COV-2 infection SARS-CoV-2 strain sera serum severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 shown Significance strain Strains Syrian hamsters the S protein transfer Vaccine vaccinee variant variant of SARS-CoV-2 variants Viral viral infectivity virus replication
[DOI] 10.1073/pnas.2106535118 PMC 바로가기 [Article Type] Comparative Study

HIV and Messenger RNA (mRNA) Vaccine

Internal Medicine

Published on 2021-07-052022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] complex conventional vaccine coronavirus DNA Efficacy Genome HIV HIV-1 HIV-2 Host Human immunodeficiency virus lentivirus Lipid nanoparticles messenger Messenger RNA mortality rate mRNA mRNA vaccine offer overcome pandemic Prophylactic Research RNA shown Therapeutic treatment Vaccine
[DOI] 10.7759/cureus.16197 PMC 바로가기 [Article Type] Internal Medicine

Efficacy of COVID-19 vaccines: From clinical trials to real life

코로나19 백신의 효능: 임상시험부터 실생활까지

Article

Published on 2021-07-012022-09-11
Journal: Thérapie [Category] SARS, 변종, 임상,

Antibody response to SARS-CoV-2 vaccination is extremely vivacious in subjects with previous SARS-CoV-2 infection

SARS-CoV-2 백신 접종에 대한 항체 반응은 이전 SARS-CoV-2 감염이 있는 피험자에서 극도로 활발합니다.

Article

Published on 2021-07-012022-09-12
Journal: Journal of medical virology [Category] MERS, SARS, 진단,

[키워드] 95% confidence interval acute respiratory syndrome Adverse Analysis applied asymptomatic infection coronavirus coronavirus disease COVID-19 dose dosing schedule Elecsy event Health care humoral Humoral immunity Immunity immunoassay immunologically individual infected individual injection interquartile range Messenger RNA Modifying mRNA mRNA vaccine naïve naïve individual naïve individuals non parametric test non-inferiority pandemic Pearson correlation SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination second dose single dose single vaccine specific antibody spike m-RNA vaccine. spike RBD subject the median U/mL vaccination Vaccine vaccine injection were measured
[DOI] 10.1002/jmv.26982 PMC 바로가기 [Article Type] Article

Long and short non-coding RNA and radiation response: a review

Review article

Published on 2021-07-012022-10-05
Journal: Translational research : the journal of laboratory [Category] 비임상,

[키워드] alteration anti-sense oligonucleotides arising ASOanti-sense oligonucleotides binding biofluids Biomarker CADcoronary artery disease Cancer Cell cellular processe cellular stress response changes in circRNAcircular RNA circular RNA Coronary artery disease DCAdicentric chromosome assay diabete diagnostic dicentric chromosome assay disease Disease progression DNA Effect EMTepithelial-to-mesenchymal transition epithelial-to-mesenchymal transition evaluate examined expression level expression profile form Future gray (unit) Gygray (unit) interactions introduced invasive ionizing radiation IRionizing radiation lncRNA lncRNAlong noncoding RNA Long long noncoding RNA Messenger RNA microRNA miRNA miRNAmicroRNA modulate modulation mRNA mRNAMessenger RNA mRNAs ncRNA ncRNAnoncoding RNA ncRNAs non-coding RNA Non-small cell lung cancer noncoding RNA NSCLCnon-small cell lung cancer oxidative stress PBMCperipheral blood mononuclear cells Peripheral blood mononuclear cells piRNApiwi-interacting RNA piwi-interacting RNA prognostic biomarker Proteins Radiation radiation exposure Radiotherapy reactive oxygen species regulate reported Research RNA RNA expression RNA interference RNAiRNA interference ROSreactive oxygen species serum short hairpin RNA shown shRNAshort hairpin RNA siRNAsmall interfering RNA Small interfering RNA small nuclear RNA small nucleolar RNA snoRNAsmall nucleolar RNA snRNAsmall nuclear RNA stability Stress TBItotal body irradiation therapeutic use thought total body irradiation transfer RNA tRNAtransfer RNA untranslated region UTRuntranslated region
[DOI] 10.1016/j.trsl.2021.02.005 [Article Type] Review article

Mn 2+ coordinates Cap-0-RNA to align substrates for efficient 2′- O -methyl transfer by SARS-CoV-2 nsp16

MN 2+ SARS-COV-2 NSP16에 의한 효율적인 2'-O- 메틸 전달에 대한 기질을 정렬하는 CAP-0-RNA를 좌표

Research Article

Published on 2021-06-292022-09-10
Journal: Science Signaling [Category] MERS, SARS, 치료기술,

[키워드] absence active site adenosylmethionine aligning Alter backbone binding biochemical capping catalysis coactivator complex conserved Coordinate coronavirus Coronaviruses Degradation Donor drug design efficient ENCODE enzyme Final generate heterodimeric Host host cell host defenses inhibitors innate response insert Interaction mammalian Messenger RNA metal ion metal ions methyl group methyltransferase mRNA nsp10 organism Prevent PROTECT resulting ribonucleotide ribonucleotides RNA RNAs SAM SARS-CoV-2 SARS-CoV-2 genome selective structural evidence Structure structures substrate substrates the SARS-CoV-2 transfer translation triggering unique Viral viral RNAs virus replication X-ray structure
[DOI] 10.1126/scisignal.abh2071 PMC 바로가기 [Article Type] Research Article

A Summary of the SARS-CoV-2 Vaccines and Technologies Available or under Development

Review

Published on 2021-06-222022-10-28
Journal: Pathogens [Category] COVID-19,