Effects of curcumin-piperine co-supplementation on clinical signs, duration, severity, and inflammatory factors in patients with COVID-19: a structured summary of a study protocol for a randomised controlled trialCOVID-19 환자의 임상 징후, 기간, 중증도 및 염증 요인에 대한 커큐민-피페린 공동 보충제의 효과: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-12-172022-09-10 Journal: Trials [Category] 임상, [키워드] 1:1 age analyses anticipated Anticoagulant anticoagulant drugs assigned Blinding calculated Capsule clinical Clinical signs Clinical symptoms clinical trial clinical trials Co-supplementation completion conducted control group coronavirus coronavirus disease COVID-19 Curcumin Curcumin-piperine Diagnosis dinner disease Disease duration dissemination double-blind drugs Effect Efficacy element Enrollment exclusion criteria female Gender hospital hospital ward Hospital wards ICU include independent Inflammatory factor inflammatory factors inflammatory mediator Inflammatory mediators Inpatient intensive care intensive care unit Intervention Iran less male maltodextrin matching placebo mediators Medical Sciences number objective outcome Outpatient packaged Parallel Arm participant Patient patients PCR test piperine Placebo placebo-controlled placebo-controlled clinical trial protocol provided randomised randomised controlled trial Randomized Randomly receive Registered registration date registry researcher Sample size sealed sensitivity sequence severity status Stratification Study protocol supplementary material title total sample size Trial Trial registration turmeric university Version Warfarin website [DOI] 10.1186/s13063-020-04924-9 PMC 바로가기 [Article Type] Letter
Novel risk scoring system for predicting acute respiratory distress syndrome among hospitalized patients with coronavirus disease 2019 in Wuhan, ChinaResearch Article Published on 2020-12-172022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] 95% confidence interval acute respiratory distress Admission ARDS assigned Blood urea nitrogen characteristic Cohort consecutive patient coronavirus disease COVID-19 cutoff value D-dimer ferritin level high risk high-risk patient Hosmer–Lemeshow test hospitalized patient identify Intervention logistic regression model mortality rate novel participant patients with COVID-19 procalcitonin Randomly required Result risk risk factor risk score scoring system selected sensitivity specificity supplementary material syndrome test dataset total score training dataset were used with COVID-19 Wuhan, China [DOI] 10.1186/s12879-020-05561-y PMC 바로가기 [Article Type] Research Article
Psychiatry during the Covid-19 pandemic: a survey on mental health departments in ItalyResearch Article Published on 2020-12-162022-10-27 Journal: BMC Psychiatry [Category] COVID-19, [키워드] activities activity Admission aggressiveness Analysis Care carried Community conducted consequence Contact COVID COVID-19 Department drastic reduction Emergency Epidemic expected Fisher Exact functioning head increase in Inpatient introduced Italian Italy mental health Mental health departments mental health service online questionnaire pandemic Pandemics Patient patients Personal protective equipment PPE problem Psychiatric psychiatric assistance Questionnaires reduced Registered remote reported response restrictions Result returned severe cases Significant square supplementary material Swab symptomatic Treatment unit ward Yates correction [DOI] 10.1186/s12888-020-02997-z PMC 바로가기 [Article Type] Research Article
Psychiatry during the Covid-19 pandemic: a survey on mental health departments in ItalyResearch Article Published on 2020-12-162022-10-27 Journal: BMC Psychiatry [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] activities activity Admission aggressiveness Analysis Care carried Community conducted consequence Contact COVID COVID-19 Department drastic reduction Emergency Epidemic expected Fisher Exact functioning head increase in Inpatient introduced Italian Italy mental health Mental health departments mental health service online questionnaire pandemic Pandemics Patient patients Personal protective equipment PPE problem Psychiatric psychiatric assistance Questionnaires reduced Registered remote reported response restrictions Result returned severe cases Significant square supplementary material Swab symptomatic Treatment unit ward Yates correction [DOI] 10.1186/s12888-020-02997-z PMC 바로가기 [Article Type] Research Article
Collateral damage of the COVID-19 pandemic: an alarming decline in critical procedures in otorhinolaryngology in a German university hospitalHead and Neck Published on 2020-12-152022-10-31 Journal: European archives of oto-rhino-laryngology : offic [Category] COVID-19, MERS, SARS, [키워드] analyzed Cancer caused Collateral coronavirus COVID-19 COVID-19 pandemic Critical diagnose Diagnosis diagnostic procedure Effect Elective surgery ENT evaluated Head and neck surgery hospital include malignancy oncology pandemic patients Result subset supplementary material Surgical Procedure symptom duration Treatment university hospital [DOI] 10.1007/s00405-020-06519-1 PMC 바로가기 [Article Type] Head and Neck
Hierarchical Modelling of COVID-19 Death Risk in India in the Early Phase of the PandemicSpecial Issue Article Published on 2020-12-152022-11-01 Journal: The European Journal of Development Research [Category] COVID-19, [키워드] Bayesian model build census conditions COVID-19 Data combining death epidemic modelling Factors family Health Hierarchical Hierarchical model IMPROVE India Latent variable morbidity obesity Older outcome pandemic phase Policy populations risk SARS-CoV2 virus pandemic severe COVID-19 supplementary material survey the epidemic Transmission World Health Organisation [DOI] 10.1057/s41287-020-00333-5 PMC 바로가기 [Article Type] Special Issue Article
Transcriptome analysis reveals modulation of the STAT family in PEDV-infected IPEC-J2 cellsResearch Article Published on 2020-12-142022-10-28 Journal: BMC Genomics [Category] Coronavirus, MERS, [키워드] Analysis analyzed binding site Cell cells classical cytokine receptor described differentially expressed differentially expressed gene disease downregulated Enhancing epidemic diarrhea epithelial cell line examined FIVE Genes Genetic Host host cell host response immune response imperative Infection Inflammatory response influenza A Interaction intestinal involved IPEC-J2 knowledge modulation molecular mechanism Pathogenesis Pathways PEDV promoter region regulatory network response Result reveal RNA-Seq sequence significantly STAT STAT family suggested supplementary material TNF signaling Transcription transcription factor transcriptome analysis transcriptomic transcriptomic analysis transcriptomic profile upregulated virus [DOI] 10.1186/s12864-020-07306-2 PMC 바로가기 [Article Type] Research Article
Host metabolism dysregulation and cell tropism identification in human airway and alveolar organoids upon SARS-CoV-2 infectionSARS-CoV-2 감염 시 인간의 기도 및 폐포 오르가노이드에서 숙주 대사 조절 장애 및 세포 친화성 식별Research Article Published on 2020-12-122022-09-10 Journal: Protein & Cell [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition airway alveolar animals AT2 Cancer cells caused Cell cell line cell lines cell tropism cells cellular metabolism ciliated club Complete coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Culture distal downregulation Drug discovery dysregulation embryonic embryonic stem cells human airway human lung organoid human lung organoids humans immune response in vitro infect infected cell infected cells Infection inhibited lipid metabolism lung organoids Lungs mechanism metabolic processes metabolism neutralizing antibody Organoid organoids organs pandemic pathophysiological physiological condition physiological conditions proximal Remdesivir replicated respiratory respiratory droplet Respiratory droplets RNA-Seq route SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication severe acute respiratory syndrome Coronavirus Spread stem cell supplementary material therapeutic drug upregulation virus infection [DOI] 10.1007/s13238-020-00811-w PMC 바로가기 [Article Type] Research Article
Temporal changes in laboratory markers of survivors and non-survivors of adult inpatients with COVID-19COVID-19 성인 입원 환자의 생존자와 비생존자의 실험실 마커의 시간적 변화Comparative Study Published on 2020-12-112022-08-31 Journal: BMC Infectious Diseases [Category] MERS, SARS, 바이오마커, [키워드] acidity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 albumin albumin-globulin ratio alkaline phosphatase Analysis aspartate Aspartate aminotransferase base excess Bicarbonate Blood blood cell blood cell count C-reactive protein calcium carbon dioxide caused Cell changes changes in cholesterol cholinesterase Clinical characteristics clinician coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 creatine creatine kinase cystatin C D-dimer death Degradation Degradation product determine diagnosed with COVID-19 distribution eosinophil Eosinophil count estimated glomerular filtration rate Extracellular Extracellular fluid FIBRIN filtration rate fluorescent fraction glomerular filtration rate Glucose Haemoglobin high risk High-density lipoprotein High-density lipoprotein cholesterol Hospitalized hypersensitive C-reactive protein immature Inpatient International international normalized ratio Laboratory Laboratory test Laboratory tests Lactate lactate dehydrogenase lipoprotein cholesterol lymphocyte Lymphocyte count Magnesium marker mean platelet volume Mild monocyte Myoglobin neutrophil neutrophil count nitrogen non-survivor Non-survivors normalized occurred ogen outbreak Patient patient condition phosphatase phosphorus plasma plasma urea Platelet Platelet count platelet distribution width prealbumin procalcitonin progression Protein prothrombin Prothrombin time red blood cell red blood cell count Result SARS-CoV − 2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe disease significant difference significant differences significantly significantly increased sodium supplementary material survivor Temporal Temporal changes test results total calcium Total cholesterol total protein Treatment Triglyceride urea urea nitrogen uric acid variable variables Volume White blood cell white blood cell count width with COVID-19 Wuhan [DOI] 10.1186/s12879-020-05678-0 PMC 바로가기 [Article Type] Comparative Study
Maximum chest CT score is associated with progression to severe illness in patients with COVID-19: a retrospective study from Wuhan, China최대 흉부 CT 점수는 COVID-19 환자의 중증 질환 진행과 관련이 있습니다: 중국 우한의 후향적 연구Research Article Published on 2020-12-112022-09-01 Journal: BMC Infectious Diseases [Category] MERS, SARS, 진단, [키워드] 95% confidence interval association characteristic Chest computed tomography Chest CT chronic obstructive chronic obstructive pulmonary disease clinical parameter Clinical parameters Combination Computed tomography COPD coronavirus disease Coronavirus disease 2019 COVID-19 CT score demographic Deterioration diagnosed Disease progression electronic medical record electronic medical records enrolled evaluated Health Health crisis hospitalized patient hospitalized patients identify information Laboratory Limited male maximum medical records moderate Moderate COVID-19 multivariable logistic regression Multivariate regression obstructive pulmonary disease Older pandemic Patient Pneumonia Predictive Predictive value progressed progression pulmonary disease radiological receiver operating characteristic receiver operating characteristic curve Result retrospective Retrospective study risk factor Risk factors ROC severe disease single-center study supplementary material Symptom Symptoms were used Wuhan Wuhan, China [DOI] 10.1186/s12879-020-05683-3 PMC 바로가기 [Article Type] Research Article