Network analysis of Down syndrome and SARS-CoV-2 identifies risk and protective factors for COVID-19
다운 증후군 및 SARS-CoV-2의 네트워크 분석은 COVID-19에 대한 위험 및 보호 요인을 식별합니다.
Article
[키워드] acute respiratory distress
acute respiratory distress syndrome
Affect
affected
Analysis
analyzed
Anti-viral
anti-viral response
Bacterial infection
clinical outcomes
complications
COVID-19
COVID-19 pandemic
COVID-19 prognosis
cytokine
Cytokine storm
datasets
deregulated
differentially expressed
Down syndrome
downregulation
favor
Gene regulatory networks
General population
Genes
higher risk
homeostasis
host cells
host protein
host proteins
identify
individual
Infection
infections
inflammatory gene
inflammatory genes
inhibiting
initial
interferon
involved
maintenance
molecular
multiple comorbidities
multiple comorbidity
network
NLRP3
overlap
Pathogenesis
pathogenic
pathway
populations
pro-inflammatory
Prognosis
Protective
protective factor
respiratory
respiratory complication
Respiratory complications
respiratory distress
Respiratory distress syndrome
risk
risk factor
Risk factors
risk of infection
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV2 infection
Signaling
Spread
susceptibility
susceptible
syndrome
TMPRSS2
transcriptomic
upregulated
upregulation
Viral
viral genome
Viral protein
Viral proteins
viral replication
viral S
viral S protein
Vulnerable populations
[DOI] 10.1038/s41598-021-81451-w PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41598-021-81451-w PMC 바로가기 [Article Type] Article