Recurrence of SARS-CoV-2 nucleic acid positive test in patients with COVID-19: a report of two casesCase Report Published on 2020-11-232022-10-28 Journal: BMC Pulmonary Medicine [Category] COVID-19, Fulltext, SARS, [키워드] antibody Coronavirus disease-19 (COVID-19) COVID-19 cured discharge discharged discharged patients female hospital immune functions IMPROVE Isolation management manifestation Mild Moderate COVID-19 Nucleic acid detection nucleic acid test Patient patients with COVID-19 positive Positive test readmission recurrence SARS-CoV-2 nucleic acid serum antibodies serum antibody severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Standard of care supplementary material Symptoms Treatment [DOI] 10.1186/s12890-020-01348-8 PMC 바로가기 [Article Type] Case Report
Early changes in laboratory parameters are predictors of mortality and ICU admission in patients with COVID-19: a systematic review and meta-analysisOriginal Investigation Published on 2020-11-212022-10-30 Journal: Medical Microbiology and Immunology [Category] COVID-19, MERS, [키워드] Absolute lymphocyte count Admission ALC baseline C-reactive protein calculated change changes in Clinical outcome conducted Confidence intervals correlation COVID-19 critical cases CRP D-dimer feature FIVE help ICU admission infected patient Interpretation Intervention knowledge Laboratory laboratory abnormality laboratory parameter LDH mean difference Meta-analysis Mortality mortality rate Odds ratio outcome Patient patients predictor Prognosis Prognostic factors Prognostic value Quantitative reported resource supplementary material survival systematic review therapeutic decisions WBC White blood cell [DOI] 10.1007/s00430-020-00696-w PMC 바로가기 [Article Type] Original Investigation
Short-term impact of COVID-19 lockdown on metabolic control of patients with well-controlled type 2 diabetes: a single-centre observational studyCOVID-19 잠금이 잘 조절되는 제2형 당뇨병 환자의 대사 조절에 미치는 단기 영향: 단일 센터 관찰 연구Observational Study Published on 2020-11-212022-09-01 Journal: Acta Diabetologica [Category] MERS, 임상, 진단, [키워드] absence applied characterized COVID-19 COVID-19 lockdown COVID-19 pandemic diabetes Diabetic Glucose glucose control Italy lockdown Metabolic control observational study pandemic parameter Patient performed pharmacologic treatment Physical inactivity predict prohibition Result serum supplementary material tested the mean Triglyceride triglycerides type 2 diabetes Variation worsening [DOI] 10.1007/s00592-020-01637-y PMC 바로가기 [Article Type] Observational Study
Wide-awake local anaesthesia no tourniquet (WALANT) vs regional or general anaesthesia for flexor tendon repair in adults: protocol for a systematic review and meta-analysis성인의 굴곡건 수복을 위한 WALANT(광각성 국소마취 무지혈대) 대 국소 또는 전신 마취: 체계적인 검토 및 메타 분석을 위한 프로토콜Protocol Published on 2020-11-212022-08-31 Journal: Systematic Reviews [Category] Coronavirus, meta-analysis, SARS, [키워드] (epinephrine Abstract Adrenaline Aerosol generation anaesthesia Anaesthetics approach article best CINAHL clinical trial Cochrane Library comparator complications conducted conscious COVID-19 database determine epinephrine evaluate Evidence feasible Finger injuries Flexor tendon Flexor tendon injury flexor tendons functional general anaesthesia Grey Grey literature hand Hand injuries hand surgery healthcare professionals help IMPROVE include Injury intubation investigator knowledge language limitation Local Meta-analysis Methodological quality motion occur open operative time outcome outcome measures Patient peer review Penetrating penetrating injury Potential Primary outcome protocol random effect range of motion reduced reduced risk Referral Registered removal repair required resolved resource risk secondary Secondary outcomes spread to standard treatment Study protocol supplementary material surgeon surgery surgical systematic review Tendon injuries tourniquet undergo WALANT Wide-awake Wide-awake local anaesthesia no tourniquet wrist [DOI] 10.1186/s13643-020-01532-1 PMC 바로가기 [Article Type] Protocol
Vaccines to prevent COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING VACCINE Project)코로나19 예방 백신: 개별 환자 데이터를 포함하는 네트워크 메타 분석을 통한 살아있는 체계적인 검토를 위한 프로토콜(The LIVING VACCINE Project)Protocol Published on 2020-11-202022-09-10 Journal: Systematic Reviews [Category] COVID-19, meta-analysis, SARS, [키워드] active placebo acute respiratory syndrome acute respiratory syndrome coronavirus aggregate data meta-analyses all age groups all-cause mortality analyzed approach assessment assessments best cause CENTRAL certainty certainty of evidence Clinical research clinical trial registries clinical trial registry clinical trials confidence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 database dendritic dendritic cell described development Diagnosis disease Effect events Evidence GRADE identify inactivated include individual patient data meta-analyses life Messenger RNA meta-analyses Mortality network Network meta-analysis non-serious adverse non-serious adverse events not limited observational studies observational study once a week outcome pandemic participant patient data Placebo prevalent Prevent Primary outcomes Protein Protein subunit protocol Quality of life randomized clinical trial randomized clinical trials Research respiratory risk of bia SARS-CoV-2 secondary Secondary outcomes Serious Adverse Events severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread standard care supplementary material systematic review Trial trial sequential analyses Vaccine vaccine for COVID-19 Vaccines Viral Viral vector [DOI] 10.1186/s13643-020-01516-1 PMC 바로가기 [Article Type] Protocol
GIS-based approaches on the accessibility of referral hospital using network analysis and the spatial distribution model of the spreading case of COVID-19 in Jakarta, IndonesiaResearch Article Published on 2020-11-202022-10-28 Journal: BMC health services research [Category] COVID-19, [키워드] Analysis approach confirmed cases country COVID-19 deaths determine distribution effective Ellipse evaluate GIS Government growth Health care Health Service hospital implementation Indonesia Jakarta Local matrix network analysis Novel coronavirus observation Origin-destination cost matrix outbreak performed Referral Referral hospital Result Service area social distancing Spatial distribution Spread Standard Standard deviational ellipse supplementary material Support Treatment West [DOI] 10.1186/s12913-020-05896-x PMC 바로가기 [Article Type] Research Article
Before-and-after online community survey on knowledge and perception of COVID-19 pandemicResearch Article Published on 2020-11-192022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] Analysis approach attacked Before-and-after study change changed changes in collected Community concerning COVID-19 COVID-19 pandemic facial group groups healthcare highlight Impact initial investigated Isolation knowledge Kruskal-Wallis tests less lockdown management Mask measure medical personnel non-parametric test Nurse Nurses online survey pandemic Pearson performed physician Poland Prevent professional professionals progression quarantine questionnaire reported Respiratory system respondent response Result second wave square supplementary material Symptom Symptoms symptoms of COVID-19 Transmission were assessed [DOI] 10.1186/s12879-020-05602-6 PMC 바로가기 [Article Type] Research Article
The COVID-19 pandemic preparedness simulation tool: CovidSIMResearch Article Published on 2020-11-192022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] Case isolation classical Contact Control intervention COVID-19 pandemic Effect effective efficient example extension fluctuation home infected individual Infection Isolation management mathematical model mechanism parameter quarantine reduce reduction Result SARS-CoV-2 seasonal variation SEIR SEIR model Simulation social distancing supplementary material Support the disease the epidemic Transmissibility Version [DOI] 10.1186/s12879-020-05566-7 PMC 바로가기 [Article Type] Research Article
Elevated markers of thrombo-inflammatory activation predict outcome in patients with cardiovascular comorbidities and COVID-19 disease: insights from the LEOSS registry혈전-염증 활성화의 상승된 마커는 심혈관 동반 질환 및 COVID-19 질병이 있는 환자의 결과를 예측합니다: LEOSS 레지스트리의 통찰력Original Paper Published on 2020-11-192022-09-11 Journal: Clinical Research in Cardiology [Category] 바이오마커, [키워드] 95% CI Abstract Activation adverse outcome adverse outcomes Analysis analyzed Anti-inflammatory therapy anticoagulation calculated cardiovascular comorbidities cardiovascular comorbidity cardiovascular disease clinical Clinical course Clinical data Clinical stage Coagulation collected COVID-19 COVID-19 disease COVID-19 in patient CRP elevated enrolled European IL-6 IMPROVE Infection Inflammation Laboratory marker Mortality Multivariate analysis multivariate regression analysis myocardial injury open outcome Patient patients with COVID-19 patients with SARS-CoV-2 predict predictor regression analysis SARS-COV-2 infection SARS-CoV‑2 significantly higher specific biomarker specific biomarkers starting supplementary material survey the disease troponin [DOI] 10.1007/s00392-020-01769-9 PMC 바로가기 [Article Type] Original Paper
Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV): A structured summary of a study protocol for a randomised controlled trialCOVID-19(ZILU-COV)로 인한 급성 저산소 호흡 부전 환자의 질루코플란: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-11-192022-08-13 Journal: Trials [Category] SARS, 임상, [키워드] 24 hour 24 hours acute hypoxic respiratory failure acute lung injury acute respiratory distress syndrome addition Adult patient alveolar pressure antibiotic Antibiotics anticipated arterial pressure Bacterial blinded Blinding Caregivers ceftriaxone characterized ciprofloxacin clinical Clinical course Combination comparator comparator Patients complement complement C5 inhibition complement pathways complement system component components control arm control group COVID-19 COVID-19 patient CT scan Cytokine release syndrome defined discharge discharged patient discharged patients disease dissemination Effect Efficacy and safety element eligibility criteria EudraCT exclusion criteria experimental arm Fungal infection history hospital discharge hospitalized patient hospitalized patients hospitals hypoxia hypoxic respiratory failure ICU ICUs Identifier improving oxygenation inclusion criteria individual Infection inhibiting inhibitor Interactive Web Response System invasive IV infusion LDH lead lung Lung injury lymphopenia Mechanical mechanical ventilation median meningococcal disease meningococcal infections number objective Open-label open-label trial outcome oxygen oxygen) Oxygenation pandemic PaO parameters Partial participant Participants Patient Phase 2 predict predisposition primary endpoint promote prophylactic antibiotics protocol randomisation randomised randomised controlled trial randomization Randomized receive recent recruited recruitment REDCap Registered repair mechanism Respiratory failure response Sample size SARS-COV-2 infection Serum ferritin SIGN SpO2 Standard of care status Study protocol subcutaneously supplemental oxygen supplementary material System systemic cytokine release syndrome Trial Trial registration Ventilation Version Web website zilucoplan [DOI] 10.1186/s13063-020-04884-0 PMC 바로가기 [Article Type] Letter