Extracorporeal membrane oxygenation for respiratory failure in children: the years before and after the 2009 H1N1 pandemicOriginal Article Published on 2021-01-012023-06-08 Journal: Revista Brasileira de Terapia Intensiva [Category] 신종인플루엔자, [키워드] ARDS Child extracorporeal membrane oxygenation H1N1 H1N1 subtype Human Influenza influenza A virus Pandemics Respiratory distress syndrome respiratory insufficiency survival rate [DOI] 10.5935/0103-507X.20210082 PMC 바로가기 [Article Type] Original Article
Early use of canakinumab to prevent mechanical ventilation in select COVID-19 patients: A retrospective, observational analysis일부 COVID-19 환자에서 기계적 환기를 예방하기 위한 카나키누맙의 조기 사용: 후향적, 관찰 분석Observational Study Published on 2021-01-012022-09-11 Journal: International journal of immunopathology and pharm [Category] 바이오마커, 임상, 진단, [키워드] acute respiratory distress acute respiratory distress syndrome addition adverse event adverse events Analysis antibody Biomarkers canakinumab Case series Clinical deterioration Combination control group coronavirus disease Coronavirus disease 2019 COVID-19 dose early stage Efficacy elevated evaluate Final Hyperinflammatory Hyperinflammatory response inflammatory mediator Inflammatory mediators inhibit interleukin interleukin-1β mechanical ventilation mediators Mild-to-moderate monoclonal outcome participant Patient patients with COVID-19 Prevent pro-inflammatory pro-inflammatory markers proinflammatory reactive reduced reported respiratory distress Respiratory distress syndrome Respiratory failure resulting retrospective Safe SARS-CoV-2 selected Standard of care syndrome the disease Treatment [DOI] 10.1177/20587384211059675 PMC 바로가기 [Article Type] Observational Study
Molecular Mechanisms of Vascular Damage During Lung Injury폐 손상 중 혈관 손상의 분자 메커니즘Review Published on 2021-01-012022-09-11 Journal: Advances in experimental medicine and biology [Category] 유전자 메커니즘, [키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome ADRS alveolar epithelium ARDS association behavioral risk factors change contribute COVID-19 Cytokines damage disease disease risk Disruption DNA DNA methylation endothelial activation Enzyme inhibitor Enzyme inhibitors Epigenetic epigenetics epithelial Epithelial barrier evaluate experimental model experimental models explained Factor focus Genetic genetic factors Genetic polymorphism genetic polymorphisms Genetic predisposition high mortality rate histone Histone acetylation, DNA methylation Hospitalization humans increased vascular permeability Inflammation Inflammatory response Injury intensive care lung endothelial Lung injury mechanism Modification molecular mechanism molecular mechanisms Mortality occur offer Pathogenesis phenotypic potential therapeutic target Prevent pro-inflammatory cytokines promote Research respiratory distress Respiratory distress syndrome Risk factors susceptibility syndrome systemic and local treat variety Vascular damage Vascular endothelium vascular permeability [DOI] 10.1007/978-3-030-68748-9_6 PMC 바로가기 [Article Type] Review
Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrumCOVID-19 임상 스펙트럼 전반에 걸쳐 어린이와 성인에서 SARS-CoV-2에 대한 뚜렷한 항체 반응Article Published on 2021-01-012022-09-11 Journal: Nature Immunology [Category] Fulltext, SARS, 임상, 진단, 치료기술, 치료법, [키워드] acute respiratory distress acute respiratory distress syndrome age Anti-spike antibodies Antibody Response ARDS breadth caused children clinical clinical manifestations Clinical manifestations of COVID-19 cohorts coronavirus Course COVID-19 COVID-19 cohort develop IgA antibodies IgG IgG antibodies IgG antibody IgM immune response implication independent independent of Infection Inflammatory life-threatening manifestation MIS-C N protein Neutralizing activity New coronavirus new coronavirus SARS-CoV-2 Protective reduced respiratory respiratory distress Respiratory distress syndrome Respiratory illness respiratory symptoms S protein SARS-CoV-2 SARS-COV-2 infection serological response specific antibodies syndrome the N protein the S protein [DOI] 10.1038/s41590-020-00826-9 PMC 바로가기 [Article Type] Article
Umbilical cord: an allogenic tissue for potential treatment of COVID-19탯줄: COVID-19의 잠재적인 치료를 위한 동종 조직Review Published on 2021-01-012022-09-11 Journal: Human Cell [Category] 임상, [키워드] acute respiratory distress acute respiratory distress syndrome alveolar alveolar damage ARDS associated symptoms autologous best chemokine chemokines clinical Clinical studies clinical study compassionate use complications controlled trials coronavirus COVID-19 COVID-19 pandemic Cytokines demonstrated detrimental effective Efficacy Evidence Factors globe Health care Health care system health care systems Hope immunomodulatory immunomodulatory effect lead limitations manuscript mesenchymal stem cell Mesenchymal stem cells MSC MSCs organ damage positioned Potential treatment pro-inflammatory cytokine pro-inflammatory cytokines randomized, controlled trial reduce regenerative respiratory distress Respiratory distress syndrome Safe SARS-COV-2 infection Symptom Symptoms syndrome therapeutic use therapy for COVID-19 tissue tissue repair treat Treatment treatment of COVID-19 umbilical Umbilical cord Vaccine Wharton's Jelly Wharton’s jelly Wharton’s jelly. [DOI] 10.1007/s13577-020-00444-5 PMC 바로가기 [Article Type] Review
Impact of liberal versus conservative saturation targets on gas exchange indices in COVID-19 related acute respiratory distress syndrome: a physiological studyOriginal Article Published on 2021-01-012022-10-29 Journal: Revista Brasileira de Terapia Intensiva [Category] COVID-19, SARS, [키워드] acute respiratory distress affected applied artificial clinical consecutive patient COVID-19 diagnosis of COVID-19 enrolled fraction functional Gas exchange Impact Invasive mechanical ventilation liberal moderate-severe not affected Oxygenation PaO Patient patients patients with moderate physiological protocol Pulmonary gas exchange Randomly Respiration respiratory Respiratory distress syndrome Respiratory mechanics Respiratory system selected Shunt significantly syndrome target was reduced [DOI] 10.5935/0103-507X.20210081 PMC 바로가기 [Article Type] Original Article
Early Cytokine Removal in Critical COVID-19 Patients with Extracorporeal Therapies (HA-380 plus High Volume Hemofiltration) May Prevent Progression of Acute Respiratory Distress Syndrome: Case Report체외 요법(HA-380 + 고용량 혈액여과)을 사용하는 중요한 COVID-19 환자의 조기 사이토카인 제거가 급성 호흡곤란 증후군의 진행을 예방할 수 있음: 사례 보고서Case Reports Published on 2021-01-012022-09-11 Journal: Blood purification [Category] SARS, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome Adsorption caused COVID-19 cytokine Cytokine release syndrome Deterioration distress Extracorporeal extracorporeal therapies extracorporeal therapy Gas exchange Hemadsorption Hemadsorption. hemodynamic hemofiltration management Patient Pneumonia pulmonary infiltrates removal report respiratory respiratory distress Respiratory distress syndrome severe COVID-19 suffered syndrome with COVID-19 [DOI] 10.1159/000512982 PMC 바로가기 [Article Type] Case Reports
Early Hemoperfusion for Cytokine Removal May Contribute to Prevention of Intubation in Patients Infected with COVID-19사이토카인 제거를 위한 조기 혈액 관류는 COVID-19에 감염된 환자의 삽관 예방에 기여할 수 있습니다Case Reports Published on 2021-01-012022-09-11 Journal: Blood purification [Category] SARS, 치료제, [키워드] Acute kidney injury acute respiratory distress acute respiratory distress syndrome AKI ARDS Complication Continuous Continuous renal replacement therapy COVID-19 CRRT cytokine Cytokines diagnosed with COVID-19 distress early stage early stages gradually declining Hemoperfusion hospital Hospitalized inflammatory mediator Inflammatory mediators intensive care intensive care unit intubation liver liver failure mediators Mortality multiple organ failure O2 Saturation oxygen oxygen mask Patient patients with COVID-19 Performing Prevent prevented prevention progression reached reduced removal renal renal replacement therapy replacement therapy respiratory distress Respiratory distress syndrome Septic shock syndrome the patient transferred Treatment with COVID-19 [DOI] 10.1159/000509107 PMC 바로가기 [Article Type] Case Reports
Pharmacological Inhibition of MMP3 as a Potential Therapeutic Option for COVID-19 Associated Acute Respiratory Distress SyndromeCOVID-19 관련 급성 호흡 곤란 증후군에 대한 잠재적인 치료 옵션으로서 MMP3의 약리학적 억제Article Published on 2021-01-012022-09-11 Journal: Infectious disorders drug targets [Category] MERS, 바이오마커, 치료기술, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome ARDS ARDS patient ARDS patients bacterial lipopolysaccharide Biomarker coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Early detection elevated high mortality inhibition Laboratory lipopolysaccharide matrix mediator mice MMP3 molecular mechanism molecular mechanisms option organ Patient plasma Potential Previous studies previous study progression reduce reduce mortality reported respiratory respiratory distress Respiratory distress syndrome severity stromelysin1 switch syndrome therapeutic treat virus infection [DOI] 10.2174/1871526520666201116100310 PMC 바로가기 [Article Type] Article
D-Dimers Level as a Possible Marker of Extravascular Fibrinolysis in COVID-19 PatientsArticle Published on 2020-12-242022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI abnormality absence Activation analysed baseline Chest computed tomography contribute coronavirus COVID-19 COVID-19 patient Critical CRP level evidenced fibrin degradation product fibrinolysis haemostasis hospitalized COVID-19 patient ICU In-hospital death include increase in independent Inflammatory intensive care less Level Lung injury marker mechanism Occurrence outcome Patient primary endpoint Prognostic value quantification Respiratory distress syndrome secondary outcome significantly Stage stage 2 threshold thrombosis Thrombotic events transfer virus infection [DOI] 10.3390/jcm10010039 PMC 바로가기 [Article Type] Article