Characteristics and outcomes in hospitalized COVID-19 patients during the first 28 days of the spring and autumn pandemic waves in Milan: An observational prospective study밀라노의 봄과 가을 유행성 파도의 첫 28일 동안 입원한 COVID-19 환자의 특성 및 결과: 관찰 전향 연구Observational Study Published on 2021-03-012022-09-11 Journal: Respiratory medicine [Category] 임상, 치료제, [키워드] Administered Adult patients anticoagulation Changing Characteristics Clinical studies comparable Corticosteroid Corticosteroids COVID-19 COVID-19 patients COVID-19 pneumonia CPAP D-dimer Dexamethasone discharged home distress Effect enoxaparin FEU Healthcare system Hospital mortality Hospital stay hospitalized COVID-19 patient hospitalized COVID-19 patients Hydroxychloroquine in-hospital mortality initiated International intubation Italy Lopinavir Lopinavir/ritonavir males material Methylprednisolone Mortality observational study outcome oxygen oxygen mask oxygen masks pandemic Patient patients hospitalized Pneumonia proportion Prospective Study recommendations reduced regimen Remdesivir respiratory respiratory distress Respiratory failure Ritonavir severe pneumonia severe respiratory failure systemic corticosteroid systemic corticosteroids therapeutic Therapeutic approach Thromboprophylaxis thrombosis Treatment were given with COVID-19 [DOI] 10.1016/j.rmed.2021.106323 PMC 바로가기 [Article Type] Observational Study
Predictors and outcomes of healthcare-associated infections in COVID-19 patientsCOVID-19 환자의 의료 관련 감염 예측 및 결과Article Published on 2021-03-012022-09-12 Journal: International Journal of Infectious Diseases [Category] SARS, 진단, [키워드] 95% CI Acute kidney injury Care center Characteristics Control COVID-19 COVID-19 patient death fungal HAI Hemodialysis higher odd Hospitalized hospitalized COVID-19 patients Hydroxychloroquine in-hospital mortality increased risk Infection morbidity and mortality multivariable logistic regression outcome Patient patients prevention secondary secondary infections steroid Tocilizumab Viral illness was used [DOI] 10.1016/j.ijid.2020.11.135 PMC 바로가기 [Article Type] Article
Propolis, Bee Honey, and Their Components Protect against Coronavirus Disease 2019 (COVID-19): A Review of In Silico, In Vitro, and Clinical Studies프로폴리스, 꿀벌 꿀 및 그 구성 요소는 코로나바이러스 질병 2019(COVID-19)로부터 보호합니다: In Silico, In Vitro 및 임상 연구에 대한 검토Review Published on 2021-02-252022-09-10 Journal: Molecules [Category] MERS, 임상, 치료제, [키워드] ACE-II activities Anti-inflammatory antioxidant Antiviral antiviral drug Antiviral effect Antiviral treatment bee bee honey bee products caffeic acid clinical Combination component Compound coronavirus disease Coronavirus disease 2019 Coronaviruses COVID -19 COVID-19 cytokine Cytokine storm discharge Effect Effects examined exhibited Express fatality flavonoids green Honey hospital hospitalized COVID-19 patient hospitalized COVID-19 patients host cells immune immunomodulatory in silico in vitro inhibit inhibited less Liposome Luteolin main protease molecular docking/biochemical modeling molecular simulations Mortality naringin natural Nigella Sativa non-structural protein non-structural proteins Prophylactic Propolis randomized clinical trials receiving Remdesivir respiratory review rutin SARS-CoV-2 SARS-COV-2 infection Severe acute respiratory syndrome spike glycoprotein standard care Symptom the cytokine storm these compound these compounds Treatment treatment for COVID-19 Treatment outcome Trigger Vero E6 VERO E6 cells Viral viral clearance viral replication viral spike viral-host interaction virulence [DOI] 10.3390/molecules26051232 PMC 바로가기 [Article Type] Review
Diagnosis, clinical characteristics, and outcomes of COVID-19 patients from a large healthcare system in northern New Jersey뉴저지 북부의 대규모 의료 시스템에서 COVID-19 환자의 진단, 임상 특성 및 결과Article Published on 2021-02-232022-09-01 Journal: Scientific Reports [Category] MERS, 임상, 진단, 치료기술, 치료법, [키워드] age analyzed case sery center Chain Reaction Characteristics clinical Clinical characteristics Clinical data clinical feature Clinical features collected Community consecutive patient consecutive patients correlated correlation COVID-19 COVID-19 pandemic COVID-19 patient cycle demographics diagnose Diseases females finding Hackensack University Medical Center Health care healthcare Healthcare system hospital Hospitalized hospitalized COVID-19 hospitalized COVID-19 patient hospitalized COVID-19 patients house indicated Infection information interquartile range intervals IQR laboratory-confirmed linear median age Medical research Meridian Microbiology New outcome outcomes Patient patient population polymerase chain polymerase chain reaction Research RT-PCR RT-PCR test significantly higher statistically significant survival The United States threshold United States university Viral Viral load virus virus test with infection [DOI] 10.1038/s41598-021-83959-7 PMC 바로가기 [Article Type] Article
Antibody affinity maturation and plasma IgA associate with clinical outcome in hospitalized COVID-19 patients입원한 COVID-19 환자의 임상 결과와 관련된 항체 친화도 성숙 및 혈장 IgAArticle Published on 2021-02-222022-09-12 Journal: Nature Communications [Category] MERS, 바이오마커, 진단, 치료기술, [키워드] Affinity maturation Analysis antibodies antibody antibody affinity Antibody binding antibody kinetics association binding antibodies clinical disease Clinical outcome Clinical severity Clinical symptoms COVID-19 COVID-19 disease COVID-19 patient Critical cytokine disease epitope Exacerbation fusion peptide hACE2 high plasma level high plasma levels hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient hospitalized patients ICU patient ICU Patients IgA IgA level IL-6 IL-8 immune parameter immune response immune responses immunopathology lead maturation MCP-1 neutralization titers non-ICU outcome patients with COVID-19 peptide plasma plasma sample prefusion receptor binding motif SARS-CoV-2 SARS-CoV2 infection scrutiny severity Spike protein Survivors sustained the SARS-CoV-2 TNFα Viral host response viral infection [DOI] 10.1038/s41467-021-21463-2 PMC 바로가기 [Article Type] Article
Neurological Disorders Associated With COVID-19 Hospital Admissions: Experience of a Single Tertiary Healthcare CenterNeurology Published on 2021-02-192022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] addition Admission age Anosmia Autoimmune categories center Cohort Confusion COVID-19 COVID-19 infection COVID-19 patient Critical care database delirium determine diagnosed disorder Effect Encephalitis Encephalopathy etiology event experience Features FIVE Follow-up functional Hemorrhagic hospitalized COVID-19 patients hospitalized patient incidence Infection Inflammatory Inpatient Laboratory lack longitudinal males Multiple nervous system neurological deficits Neurological disorder Neurological disorders neurological phenotype Neurological symptom Neurological symptoms NEUROLOGY non-specific outcome Patient Prevalence radiological required sclerosis Seizures Seven stroke Tertiary the SARS-CoV-2 the WHO Treatment response [DOI] 10.3389/fneur.2021.640017 PMC 바로가기 [Article Type] Neurology
Sonographic findings in coronavirus disease-19 associated liver damageClinical Trial Published on 2021-02-192022-10-04 Journal: PLoS ONE [Category] MERS, 임상, [키워드] addition cholestasis Clinical data Complication complications conducted coronavirus disease Coronavirus disease-19 correlated COVID-19 COVID-19 patient death elevated emergency ward evaluate evaluated gall bladder Hepatitis hepatomegaly high mortality histologic hospitalized COVID-19 patients Hyperinflammatory syndrome inflammatory complication information intensive care liver Liver damage liver enzyme liver enzymes liver parenchyma Local macrophage activation material medical record Mild moderate Patient patients positive powerful tool recorded Result Retrospective study SARS-CoV-2 screened severely ill patient severity Sonography specimen tested Ultrasound Vascular was performed [DOI] 10.1371/journal.pone.0244781 PMC 바로가기 [Article Type] Clinical Trial
Clinical outcomes of initially asymptomatic patients with COVID-19: a Korean nationwide cohort studyResearch Article Published on 2021-02-132022-10-28 Journal: Annals of Medicine [Category] COVID-19, [키워드] Admission age Analysis Asymptomatic asymptomatic infections clinical Clinical outcome clinician cohort study Comorbidity COVID-19 died discharged group hospitalized COVID-19 patients ICU ICU care identify initial initially asymptomatic patient initially asymptomatic patients intensive care Isolation Korean Mortality mortality rate mortality risk not different outcome Patient patient mortality predict predictor Prevalence receive Result retrospective risk factor risk of death Symptom symptomatic infection symptomatic patient Symptomatic patients was performed [DOI] 10.1080/07853890.2021.1884744 PMC 바로가기 [Article Type] Research Article
Systematic review and subgroup analysis of the incidence of acute kidney injury (AKI) in patients with COVID-19Research Article Published on 2021-02-052022-10-28 Journal: BMC Nephrology [Category] COVID-19, MERS, [키워드] Acute kidney injury age AKI conducted Coronavirus disease-19 COVID-19 COVID-19 patient COVID-19 patients CRRT disease severity evaluate Evidence hospitalized COVID-19 patient hospitalized COVID-19 patients in-hospital mortality incidence indicated induce investigated Kidney injury occur package in R Patient patients with COVID-19 proportion provide Remdesivir renal replacement therapy Result SARS-COV-2 infection subgroup subgroup analysis supplementary material systematic review treated Treatment was performed Web of Science [DOI] 10.1186/s12882-021-02244-x PMC 바로가기 [Article Type] Research Article
Association between markers of immune response at hospital admission and COVID-19 disease severity and mortality: A meta-analysis and meta-regression입원 시 면역 반응 지표와 COVID-19 질병 중증도 및 사망률 간의 연관성: 메타 분석 및 메타 회귀Meta-Analysis Published on 2021-02-012022-09-11 Journal: Journal of medical virology [Category] Fulltext, MERS, 바이오마커, [키워드] 95% CI 95% confidence interval Adaptive immune response Admission Adult patients age age and sex ALC ANC articles association C-reactive protein C-reactive protein (CRP calculate candidate Coagulation conducted coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 disease severity D-dimer determine disease severity ferritin groups highlight Hospital admission hospitalized COVID-19 patient hospitalized COVID-19 patients hyper inflammation identify IL-6 immune response inclusion criteria interleukin interleukin-6 Intervention intravascular coagulation Laboratory laboratory values LDH lymphocyte Lymphocytes marker material mean difference Meta-analysis meta-regression Mortality neutrophil Neutrophils Pathogenesis pathogenesis of COVID-19 Patient patients random effect sensitivity Sex statistically significant subsequent systematic review the WHO troponin I utility was used [DOI] 10.1002/jmv.26411 PMC 바로가기 [Article Type] Meta-Analysis