Glucosamine stimulates pheromone-independent dimorphic transition in Cryptococcus neoformans by promoting Crz1 nuclear translocation글루코사민은 Crz1 핵 전위를 촉진하여 Cryptococcus neoformans에서 페로몬 독립적인 이형 전이를 자극합니다Research Article Published on 2017-09-122022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Affect Antifungal antifungal therapy attenuate calcineurin caused Cell cellular response clinically complex component Cryptococcal cells cryptococcal meningitis cryptococcosis Cryptococcus Cryptococcus neoforman Cryptococcus neoformans cytoplasm demonstrated disease downstream effector effectors elicited fertile fungal Genetic genetic screen glucosamine glycerol Host Host immune response host immune responses hosts identity immune responses immune-stimulatory independent independent of Interaction isolate limitations majority mammalian MAPK Meningitis morphogenesis Morphological morphological change Morphotype nuclear translocation nucleus Pathogenesis pathway pheromone phosphatase promote promoted PROTECT raise recent reference strain responsible serotype shown signaling pathway stimulate stimulated strain Stress stress response subsequent suppressed switching transcription factor translocation Trigger undergo Vaccine Vaccine development virulence virulent yeast [DOI] 10.1371/journal.pgen.1006982 PMC 바로가기 [Article Type] Research Article
Circulating predictive and diagnostic biomarkers for hepatitis B virus-associated hepatocellular carcinomaReview Published on 2016-10-072023-06-16 Journal: World journal of gastroenterology [Category] B형 간염, [키워드] Alpha-Fetoprotein Biomarkers diagnostic Hepatitis B virus infection Hepatocellular carcinoma limitations microRNA Predictive validation [DOI] 10.3748/wjg.v22.i37.8271 PMC 바로가기 [Article Type] Review
Modified Vaccinia Virus Ankara (MVA) as Production Platform for Vaccines against Influenza and Other Viral Respiratory DiseasesReview Published on 2014-07-172022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] addressed biosafety can be used caused cellular immune responses coronavirus Coronaviruses develop foreign antigen function human parainfluenza virus humoral induce Infection Influenza Influenza virus influenza viruses intrinsic limitations modified vaccinia virus Ankara multivalent vaccine Other pandemic parainfluenza virus Production protective immunity public health Regulatory replication-deficient viral vector respiratory respiratory syncytial virus respiratory virus respiratory viruses respond RSV Seasonal influenza Subtypes target Vaccine Vaccine development vaccine platform vaccinia virus [DOI] 10.3390/v6072735 PMC 바로가기 [Article Type] Review
Coronavirus reverse genetic systems: Infectious clones and repliconsArticle Published on 2014-06-122022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] acute respiratory syndrome Analysis antiviral drugs approach Bacteria Central nervous system clone coronavirus CoV CoV genome CoV replication CoVs defined Diseases gene sequence Genetic genetics Human in vitro infect infectious clones Interaction limitations overcome Pathogenesis positive replicons reverse genetic system reverse genetics RNA viruses SARS-CoV Vaccine vaccinia virus [DOI] 10.1016/j.virusres.2014.05.026 PMC 바로가기 [Article Type] Article
Immunohistochemistry as an Important Tool in Biomarkers Detection and Clinical Practice바이오마커 검출 및 임상 실습에서 중요한 도구로서의 면역조직화학Review Published on 2010-02-092022-08-08 Journal: Biomarker Insights [Category] Biochemistry, [키워드] Amino acid amino acids Analysis benefit Cell cell or tissue antigens clinical clinician collaboration complementary detection diagnostic differential diagnose differential diagnoses eosin expression Future hematoxylin Hematoxylin and eosin immunocytochemistry immunohistochemistry immunohistochemistry technique increase in infectious agent infectious agents Interpretation involved knowledge limitations methodology pathologist pathology Patient pooling Practice preparation problem problems prognostic Protein quantification reaction related Research review specific cellular populations Stage stages surgeon technique tissue antigen PMC 바로가기 [Article Type] Review