Uncovering the Depths of the Human Proteome: Antibody-based Technologies for Ultrasensitive Multiplexed Protein Detection and QuantificationReview article Published on 2021-09-282022-10-05 Journal: Molecular & Cellular Proteomics : MCP [Category] 비임상, [키워드] antibody array antibody microarray aptamer biofluid Biomarker Comparisons complement Concentration cross talk Depth detection disadvantage disease drug target discovery Human immunoassays knowledge mechanisms multiplex plasma Probing Protein Proteins proteome proteomics proximity extension assay quantification recent researcher single-molecule array technology technology advances technology comparison tissue [DOI] 10.1016/j.mcpro.2021.100155 [Article Type] Review article
Catching COVID: Engineering Peptide-Modified Surface-Enhanced Raman Spectroscopy Sensors for SARS-CoV-2코로나 잡기: SARS-CoV-2용 펩티드 수정 표면 강화 라만 분광기 센서 엔지니어링Article Published on 2021-09-242022-09-11 Journal: ACS Sensors [Category] SARS, 변종, 치료기술, [키워드] Accuracy ACE2 albumin amplification angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 biomimetic biosensor bovine bovine serum albumin complex COVID-19 Engineering generate globe highlighting IMPROVE limit of detection peptide peptide-based peptides probe provide quantification quantitative assay Raman spectroscopy SARS-CoV-2 selective selectivity sensor SERS serum albumin specificity Spectroscopy Spike protein the spike protein unique variants Viral protein Viral proteins virus viruses [DOI] 10.1021/acssensors.1c01344 PMC 바로가기 [Article Type] Article
Protocol for safe, affordable, and reproducible isolation and quantitation of SARS-CoV-2 RNA from wastewaterLab Protocol Published on 2021-09-232022-10-28 Journal: PLoS ONE [Category] COVID-19, SARS, [키워드] added addition adopted approach auxiliary benefit BSL2 facility clinically Community Concentration Department detect FIVE Genetic help Illumina include involved Isolation MONITOR New York City Prevalence protection protocol quantification quantitation RNA RNA extraction RT-qPCR Safe SARS-CoV-2 SARS-CoV-2 RNA sequenced Sequencing Spread Surveillance the SARS-CoV-2 variety viral pathogens virus [DOI] 10.1371/journal.pone.0257454 PMC 바로가기 [Article Type] Lab Protocol
Direct detection of human adenovirus or SARS-CoV-2 with ability to inform infectivity using DNA aptamer-nanopore sensorsResearch Article Published on 2021-09-222022-11-01 Journal: Science Advances [Category] COVID-19, [키워드] Adenovirus application demonstrated description detect determine Direct DNA DNA library ENhance Health Infection intact virus Nanopore novel public health quantification Saliva SARS-CoV-2 selected sensitivity serum Spread virus viruses [DOI] 10.1126/sciadv.abh2848 PMC 바로가기 [Article Type] Research Article
Curcumin Extraction, Isolation, Quantification and Its Application in Functional Foods: A Review With a Focus on Immune Enhancement Activities and COVID-19Nutrition Published on 2021-09-212022-10-31 Journal: Frontiers in Nutrition [Category] COVID-19, [키워드] activity affected application assist association coronavirus COVID-19 Curcuma Curcumin death develop enhancement extraction focus functional functional food help human health Human immune system immune system immunological activity knowledge manuscript nutraceutical occurred outbreak quantification researcher review Safe separation methods therapeutic [DOI] 10.3389/fnut.2021.747956 PMC 바로가기 [Article Type] Nutrition
Exposure of Ophthalmologists to Patients’ Exhaled Droplets in Clinical Practice: A Numerical Simulation of SARS-CoV-2 Exposure RiskPublic Health Published on 2021-09-202022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] ambient assistant breathing mode clinical computational fluid dynamics simulation coughing Course diagnostic droplet droplet transmission environmental condition equipment expiratory exposure high risk infectious risk inhalation exposure initial Interaction mucosal ophthalmic Ophthalmologist ophthalmology ophthalmoscopic pathogen Patient quantification Relative humidity SARS-CoV-2 SARS-COV-2 infection selected Simulation slit-lamp surgeon the patient Treatment were used [DOI] 10.3389/fpubh.2021.725648 PMC 바로가기 [Article Type] Public Health
Uncertainty quantification and sensitivity analysis of COVID-19 exit strategies in an individual-based transmission modelResearch Article Published on 2021-09-172022-10-28 Journal: PLoS Computational Biology [Category] Coronavirus, SARS, [키워드] Care catastrophic comprehensive analysis country COVID-19 COVID-19 epidemic COVID-19 transmission Curve distribution Efficacy flattening Health implementation infected individuals input parameter intensive care Intermittent Intervention intrinsic knowledge measure opening pandemic parameter predict prevalent quantification question raising reduction in Safe sensitivity sensitivity analysis severity Spread Stratification subject Support the epidemic tracing Transmission Transmission model Uncertainty Variability virus [DOI] 10.1371/journal.pcbi.1009355 PMC 바로가기 [Article Type] Research Article
Semi-quantitative, high throughput analysis of SARS-CoV-2 neutralizing antibodies: Measuring the level and duration of immune response antibodies post infection/vaccinationSARS-CoV-2 중화 항체의 반정량적, 고처리량 분석: 감염/백신 접종 후 면역 반응 항체의 수준 및 기간 측정Article Published on 2021-09-152022-09-12 Journal: Vaccine [Category] MERS, SARS, 진단, [키워드] ACE2 receptor agility Analysis antibody approach automated Efficacy Factor Genetic handling help host cell immune response Immunity individual Interaction methodology natural infection neutralize Neutralizing neutralizing antibody Neutralizing antibody response physiological platform presence of antibody protocol quantification question Receptor binding domain robust SARS-CoV-2 SARS-CoV-2 neutralizing antibody second dose semi-quantitative stability storage conditions subset Support Surveillance sVNT tested the SARS-CoV-2 undetectable vaccinated individuals vaccination vaccine dose virus neutralization test was used [DOI] 10.1016/j.vaccine.2021.07.098 PMC 바로가기 [Article Type] Article
Long-term monitoring of SARS-COV-2 RNA in wastewater in Brazil: A more responsive and economical approach브라질 폐수 내 SARS-COV-2 RNA의 장기 모니터링: 보다 신속하고 경제적인 접근 방식Article Published on 2021-09-152022-09-11 Journal: Water research [Category] SARS, 치료기술, [키워드] ABC agency approach Brazil can be used catastrophic Clusters collected Concentration consequence coronavirus country COVID-19 COVID-19 infection COVID-19 pandemic death Environmental surveillance Epidemiology evaluate fecal FIVE Genome Health highlight individuals Infection Local log Novel coronavirus Occurrence Outbreaks positive correlation predicted Prevalence quantification ranged Region reported RNA SARS-CoV-2 SARS-CoV-2 RNA sewage South America Spread Surveillance symptomatic and asymptomatic the SARS-CoV-2 viability Viral load virus spread wastewater Wastewater-based epidemiology Wuhan Wuhan, China [DOI] 10.1016/j.watres.2021.117534 PMC 바로가기 [Article Type] Article
Variability in RT-qPCR assay parameters indicates unreliable SARS-CoV-2 RNA quantification for wastewater surveillanceRT-qPCR 분석 매개변수의 가변성은 폐수 감시를 위한 신뢰할 수 없는 SARS-CoV-2 RNA 정량화를 나타냅니다.Review Published on 2021-09-152022-09-11 Journal: Water research [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 assay validity assays conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Data analysis dataset described deviation experiment generate indicate induce lack minimum pandemic parameter parameters PCR protocols qPCR Quality assurance Quality control quantification Quantitative data quantitative measurement quantitative PCR reagents reliability reproducibility RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus Spread standard curve Surveillance the SARS-CoV-2 Variability Variation wastewater wastewater surveillance [DOI] 10.1016/j.watres.2021.117516 PMC 바로가기 [Article Type] Review