Adhesion Molecule – Page 3 – Communicable Diseases Research

High expression of neutrophil and monocyte CD64 with simultaneous lack of upregulation of adhesion receptors CD11b, CD162, CD15, CD65 on neutrophils in severe COVID-19

Original Research

Published on 2021-07-312022-10-28
Journal: Therapeutic Advances in Infectious Disease [Category] COVID-19,

A Potent Leukocyte Transmigration Blocker: GT-73 Showed a Protective Effect against LPS-Induced ARDS in Mice

강력한 백혈구 변환 차단제 : GT-73은 마우스에서 LPS- 유도 된 ARD에 대한 보호 효과를 나타냈다.

Article

Published on 2021-07-292022-08-31
Journal: Molecules [Category] SARS, 바이오마커,

[키워드] acute respiratory distress acute respiratory distress syndrome addition Adhesion Molecule affecting applied ARDS BALF bind biochemical blocked blocker Blood blood cell Bronchoalveolar lavage fluid caused cell adhesion molecule covalent inhibitor COVID-19 patient COVID-19 patients Critical Cytokine storm derivatives drug candidate Effect Endothelial cell evaluate finding histological IL-1β IL-6 infiltrating Inflammation investigated leukocyte leukocyte transmigration leukocytes lung Lungs MCP-1 Migration molecule Mortality mouse model PECAM-1 peripheral tissues Platelet potent prodrug rationale reduced respiratory distress Respiratory distress syndrome responsible Showed significantly syndrome TERT transendothelial migration transmigration Treatment unique was tested was used White blood cell
[DOI] 10.3390/molecules26154583 PMC 바로가기 [Article Type] Article

Integrins: An Important Link between Angiogenesis, Inflammation and Eye Diseases

Review

Published on 2021-07-062022-10-31
Journal: Cells [Category] COVID-19, SARS,

Pulmonary long-term consequences of COVID-19 infections after hospital discharge

퇴원 후 COVID-19 감염의 폐 장기 결과

Article

Published on 2021-06-012022-09-11
Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 바이오마커,

[키워드] 6-minute walk test 6MWT 95%CI abnormality acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adhesion Molecule Biomarker Biomarkers carbon monoxide Chest computed tomography Comorbidities Computed tomography consequence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 hospitalization COVID-19 infection diffusing diffusing capacity diffusion diffusion capacity discharge discharged patient discharged patients Effect epidemiological evaluated expiratory forced expiratory volume forced vital capacity FVC group hospital hospital discharge Hospital stay Hospitalization identify Inflammation information inhibitor inhibitors Intracellular Intracellular adhesion molecule IQR laboratory parameter Laboratory parameters laboratory-confirmed Lactate lactate dehydrogenase Limited Lung diffusion capacity Lung function matrix metalloproteinases median medical histories Multivariate analysis onset of symptom Osteoprotegerin Patient patients performed plasminogen Plasminogen activator inhibitor Proteases pulmonary Pulmonary function Pulmonary function tests Real-time PCR receptor receptors recovering from COVID-19 recruited respiratory Respiratory function Respiratory function test Respiratory function tests RT-PCR SARS-CoV-2 SARS-CoV-2-infected patient SARS-CoV-2-infected patients screened serum serum lactate severe acute respiratory syndrome Coronavirus severe disease severe SARS-CoV-2 severity Spanish Sputum sample sputum samples survivor Symptom symptom onset Tissue Inhibitor Tissue inhibitor of matrix metalloproteinases tomography virus vital capacity Volume were measured
[DOI] 10.1016/j.cmi.2021.02.019 PMC 바로가기 [Article Type] Article

Insight into the LFA-1/SARS-CoV-2 Orf7a Complex by Protein–Protein Docking, Molecular Dynamics, and MM-GBSA Calculations

Article

Published on 2021-05-272022-10-29
Journal: Journal of Chemical Information and Modeling [Category] COVID-19, MERS, SARS,

Clinical features and prognostic factors in Covid-19: A prospective cohort study

Covid-19의 임상 특징 및 예후 요인: 전향적 코호트 연구

Multicenter Study

Published on 2021-05-142022-08-31
Journal: EBioMedicine [Category] 바이오마커,

[키워드] Adhesion Molecule Admission Analysis Angiogenesis angiopoietin association Biomarker Blood CD14 cell adhesion molecule cell-cell adhesion changes in chemotaxis clinical Clinical deterioration Clinical features Coagulation Cohort complement complement component complement system Concentration Corona Corticosteroids COVID-19 COVID-19 infection Cox regression death Deterioration died Disease progression driven by End end products Endothelial dysfunction feature fibrinolysis finding funding Glycation group hospitalized patient hospitalized patients host response ICU ICU Patients IL-1-receptor IL-10 IL-6 IL-8 immunothrombosis Inflammation insight interleukin Intubated involved joint lactoferrin lead life cycle linear marker mechanisms mixed-effects models Mortality multiple pathways Necrosis outcome overlap pathway Pathway analysis Pathways Patient patients died patients with COVID-19 performed Primary outcome procalcitonin product Prognosis Prognostic factor Prognostic markers prospective cohort study receptor receptor antagonist Regulation risk severe COVID-19 therapy tissue tissue damage Tissue Factor transferred Treatment strategies Tumor tumor necrosis tumor necrosis factor urokinase Urokinase-Type Plasminogen Activator variety vascular cell adhesion VCAM-1 Viral viral life cycle ward with COVID-19 wound healing
[DOI] 10.1016/j.ebiom.2021.103378 PMC 바로가기 [Article Type] Multicenter Study

Blood neutrophils from children with COVID-19 exhibit both inflammatory and anti-inflammatory markers

COVID-19에 걸린 어린이의 혈액 호중구는 염증 및 항염증 마커를 모두 나타냅니다

Observational Study

Published on 2021-05-012022-08-31
Journal: EBioMedicine [Category] SARS, 바이오마커, 임상, 진단,

[키워드] Activation acute lung injury Adhesion Molecule adhesion molecules Adults analyzed Anti-inflammatory Asymptomatic Blood Blood samples Buenos Aire Buenos Aires CD11b CD64 CD66b Cell-adhesion molecules cell-free DNA children children with COVID-19 circulating neutrophil circulating neutrophils Concentration COVID-19 cytokine cytokine production Cytokines DNA ELISA expression Fcγ receptor flow cytometry fluorometry healthy children healthy controls HLA-DR IgG IgG antibodies IgG antibody immune response infiltration Inflammatory inhibitory receptor Inhibitory Receptors L-selectin low expression lower expression Lung function Lung injury marker Mild MIS-C Moderate COVID-19 NET NETs neutrophil Neutrophils no differences observational study PD-L1 pediatric pediatric COVID-19 phenotype plasma Plasma levels Prevent promotion quantified receptor respiratory respiratory symptoms SARS-CoV-2 Science serum severe COVID-19 severe respiratory symptom severe respiratory symptoms Spike protein supported syndrome technology the spike protein tissue university was performed were measured
[DOI] 10.1016/j.ebiom.2021.103357 PMC 바로가기 [Article Type] Observational Study

In Sickness and in Health: The Immunological Roles of the Lymphatic System

Review

Published on 2021-04-242023-08-30
Journal: International Journal of Molecular Sciences [Category] E형 간염,

[키워드] Adhesion Molecule chemokine dendritic cell high endothelial venule Inflammation Lymph node Lymphatic Migration T-cell Trafficking
[DOI] 10.3390/ijms22094458 PMC 바로가기 [Article Type] Review

SARS-CoV-2 Entry Related Viral and Host Genetic Variations: Implications on COVID-19 Severity, Immune Escape, and Infectivity

SARS-CoV-2 진입 관련 바이러스 및 숙주 유전자 변이: COVID-19 심각도, 면역 탈출 및 감염성에 미치는 영향

Review

Published on 2021-03-172022-09-10
Journal: International Journal of Molecular Sciences [Category] SARS, 변종,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus Adhesion Molecule Affect angiotensin antiviral drugs binding Cell contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical determine driving drug enzyme escape Evolution genetic diversity genetic risk Genetic variation Genetic variations Genome geographical regions glycoprotein high risk Host host protein human population human populations immune Immune escape Impact in viral Infectivity integrin intercellular intercellular adhesion molecule Mutation Pathogenesis Pathogens Population Positive selection Precision protease Protein Receptor binding domain Research respiratory S glycoprotein SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 S glycoprotein SARS-CoV-2 variant SARS-CoV-2 variants Serine serine 2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity spike glycoprotein susceptibility the cell the SARS-CoV-2 TMPRSS2 transmembrane transmembrane protease serine 2 Transmissibility Transmission variants Variation Viral viral evolution viral S virus virus transmissibility vital role vital roles
[DOI] 10.3390/ijms22063060 PMC 바로가기 [Article Type] Review

Molecular characteristics of an adhesion molecule containing cholesterol-dependent cytolysin-motif produced by mitis group streptococci

article

Published on 2021-02-282024-09-01
Journal: Microbiology and Immunology [Category] 폐렴구균 감염증,

[키워드] Adhesion Molecule cholesterol-dependent cytolysin mitis group streptococci Streptococcus mitis Streptococcus pseudopneumoniae
[Article Type] article