comprehensive analysis – Page 3 – Communicable Diseases Research

Deciphering the quality of SARS-CoV-2 specific T-cell response associated with disease severity, immune memory and heterologous response

질병 중증도, 면역 기억 및 이종 반응과 관련된 SARS-CoV-2 특이적 T 세포 반응의 품질 해독

Article

Published on 2022-04-012022-09-11
Journal: Clinical and Translational Medicine [Category] COVID19(2023년), SARS, 진단, 치료법,

SARS-CoV-2 Mutations and COVID-19 Clinical Outcome: Mutation Global Frequency Dynamics and Structural Modulation Hold the Key

SARS-CoV-2 돌연변이 및 COVID-19 임상 결과: 돌연변이 글로벌 주파수 역학 및 구조 변조가 핵심

Article

Published on 2022-03-212022-09-11
Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 변종, 유전자 메커니즘, 치료법,

[키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus addition Analysis analyzed Characteristics clinical Clinical data Clinical features Clinical outcome clinical outcomes Cohort comprehensive analysis coronavirus coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 pandemic disease disease outcome disease severity distribution driving Dynamics Effect effort Frequency Genomic surveillance global frequency flip Healthcare system identify Impact management mechanism molecular molecular dynamics Molecular dynamics simulation Mortality mortality group Mutation mutation analysis mutations nucleocapsid Occurrence outcome pandemic Patient patients performed Protein protein structure provide recovered patient recovered patients SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe disease progression significantly Spectrum stability temporal dynamics the mortality group two group two groups variants variants of concern variants of interest viral genome virus VOCs
[DOI] 10.3389/fcimb.2022.868414 PMC 바로가기 [Article Type] Article

Changes of radiological examination volumes over the course of the COVID-19 pandemic: a comprehensive analysis of the different waves of infection

Original Article

Published on 2022-03-072022-10-29
Journal: Insights into Imaging [Category] COVID-19,

Impacts of Emergency Remote Teaching on College Students Amid COVID-19 in the UAE

Article

Published on 2022-03-032022-10-29
Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS,

Identification of Distinct Immune Cell Subsets Associated With Asymptomatic Infection, Disease Severity, and Viral Persistence in COVID-19 Patients

Immunology

Published on 2022-02-222022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, COVID19(2023년), MERS, SARS,

[키워드] Analysis Apoptosis asymptomatic infection asymptomatic subject CD14 CD160 CD33 CD68 CD8 Cell CLEC10A clinical presentation comprehensive analysis COVID-19 CSF1R develop Differentially expressed genes disease severity ENhance enriched pathway help HLA-DMA identification IL1B immune response immune responses Immunopathogenesis Inflammation KEGG LAG3 monocyte NCAM1 pathogenic PBMC positively correlated Protective S100A9 SARS-CoV-2 SARS-COV-2 infection scRNA-seq severity significantly singlecell RNA sequencing (scRNA-seq) subset surface marker Symptomatic patients the disease TRAV1-2 unique viral persistence
[DOI] 10.3389/fimmu.2022.812514 PMC 바로가기 [Article Type] Immunology

Collection of Monoclonal Antibodies Targeting SARS-CoV-2 Proteins

Article

Published on 2022-02-212022-10-28
Journal: Viruses [Category] COVID-19, Fulltext, MERS, SARS,

In Silico Infection Analysis (iSFA) Identified Coronavirus Infection and Potential Transmission Risk in Mammals

Molecular Biosciences

Published on 2022-02-082022-10-31
Journal: Frontiers in Molecular Biosciences [Category] COVID-19,

Comprehensive Analysis of the ILCs and Unconventional T Cells in Virus Infection: Profiling and Dynamics Associated with COVID-19 Disease for a Future Monitoring System and Therapeutic Opportunities

Review

Published on 2022-02-042022-10-31
Journal: Cells [Category] COVID-19, COVID19(2023년), MERS, SARS,

[키워드] Activation adaptive Analysis Cell changes in clinical trials advanced therapies Cluster cohorts of patient Comprehensive comprehensive analysis COVID-19 COVID-19 affected patient Critical determine diagnostic Dynamics dysregulation Effect Express Factor Frequency function Future gamma-delta T cells highlight homeostasis Hospitalization ILC ILCs Immune status immune systems Infection innate lymphoid cell longitudinal study MAIT marker MONITOR monitoring NKT opportunity pathogenesis of COVID-19 profile Profiling prognostic biomarker question recovered patients SARS-COV-2 infection subjects Symptom System T cell Therapies therapy tissue Unconventional T cells viral respiratory pandemic with COVID-19
[DOI] 10.3390/cells11030542 PMC 바로가기 [Article Type] Review

Immune Response Is Key to Genetic Mechanisms of SARS-CoV-2 Infection With Psychiatric Disorders Based on Differential Gene Expression Pattern Analysis

면역 반응은 차등 유전자 발현 패턴 분석을 기반으로 한 정신 장애를 가진 SARS-CoV-2 감염의 유전 기전의 핵심입니다

Immunology

Published on 2022-02-042022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus affecting angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme-2 approach bioinformatics Bipolar disorder brain tissue clinical manifestation collected comprehensive analysis coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 data set data sets DEGs depressive depressive disorder differentially expressed gene disorder enrichment analysis enzyme Evidence expressed functional enrichment Gene regulation gene regulation networks Genetic genetic mechanism genetic mechanisms identify immune-related gene immune-related genes incidence individual infected with SARS-CoV-2 infecting Infection infection with SARS-CoV-2 Inflammatory responses Interaction lead leads major depressive disorder MAPK mechanism Mental disorder Mental Disorders mental health disorders Mortality overlapping pathway Patient patients with COVID-19 pattern performed Peripheral blood peripheral blood cell peripheral blood cells Protein–protein interaction Psychiatric psychiatric diagnose psychiatric disorder Psychiatric disorders psychiatric illness receptor reported Research respiratory Respiratory system response SARS-CoV-2 Schizophrenia severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 signaling pathways significantly higher susceptible susceptible cell Systems biology TGF-β Therapies Treatment various tissues were used Whole blood
[DOI] 10.3389/fimmu.2022.798538 PMC 바로가기 [Article Type] Immunology

SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses

Article

Published on 2022-02-032022-10-31
Journal: Cell [Category] COVID-19,

[키워드] Abstract ACE2 ACE2 binding ACE2 binding site ameliorated Analysis antibody Beta binding Booster vaccine change changes in comprehensive analysis convalescent convalescent patient COVID-19 pandemic Delta driven by Evolution facilitate failure Gamma Immune escape immune evasion mAb monoclonal antibody Mutation neutralization neutralization titers neutralize Neutralizing antibody response new SARS-CoV-2 omicron pandemic RBD receptor receptor interaction receptor-binding motif reduce reduced reduction in reported reveal SARS-CoV-2 selective sequence sera spike subject the SARS-CoV-2 titer vaccinated individual vaccine dose vaccinee vaccinees Vaccines variant variants virus viruses widespread
[DOI] 10.1016/j.cell.2021.12.046 PMC 바로가기 [Article Type] Article