COVID-19 variants’ cross-reactivity on the paper microfluidic particle counting immunoassayArticle Published on 2022-11-012022-11-15 Journal: Analytical and bioanalytical chemistry [Category] SARS, 변종, 진단, 치료기술, [키워드] Care COVID-19 COVID-19 pandemic cross-reactivity Delta delta variant demonstrated Determining dominant variant evaluated immunoassay Microscope monoclonal antibody mutated Mutation nucleocapsid nucleocapsid antigen nucleocapsid protein Nucleocapsid proteins omicron paper Paper microfluidic chip recognizing reported SARS-CoV-2 Smartphone smartphone microscope Spike protein Spike proteins the disease variant variants virus [DOI] 10.1007/s00216-022-04333-8 PMC 바로가기
SARS-CoV-2 Omicron BA.1 Challenge after Ancestral or Delta Infection in MiceArticle Published on 2022-11-012022-11-15 Journal: Emerging Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome ancestral antibody Australia challenge coronavirus coronavirus disease COVID-19 cross-protection cross-reactivity Delta elicited homologous immunogenicity Infection K18-hACE2 K18-hACE2 mice mice Neutralizing Neutralizing antibodies neutralizing antibody omicron Omicron BA.1 remained respiratory infections SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variants severe acute respiratory syndrome coronavirus 2 Strains vaccine-preventable diseases viruses zoonoses [DOI] 10.3201/eid2811.220718 PMC 바로가기
Optimizing Plasmodium vivax serological surveillance within a coendemic epidemiological landscapearticle Published on 2022-10-312024-09-01 Journal: Trends in Parasitology [Category] 말라리아, [키워드] cross-reactivity P. knowlesi Plasmodium vivax serological surveillance seroTAT [Article Type] article
Accessible and Adaptable Multiplexed Real-Time PCR Approaches to Identify SARS-CoV-2 Variants of ConcernArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome approach collected concern coronavirus COVID-19 COVID-19 pandemic Critical cross-reactivity Delta delta variant detect different time points equipment exhibited FIVE genotyping identify Laboratory lack Limits of detection management melting curve analysis Molecular assay multiplex Multiplex PCR Mutation mutations nine omicron Omicron variant other coronaviruses PCR PCR assay performed platform positive sample Rapid rapid genotyping. Real-time PCR resource RNA SARS-CoV-2 SARS-CoV-2 VOCs selected sensitivity Sequencing signature specificity Spike protein Support Surveillance variant variants variants of concern VoC VOCs WGS [DOI] 10.1128/spectrum.03222-22 PMC 바로가기
Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced ImmunityArticle Published on 2022-10-262022-11-15 Journal: mBio [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] accelerate antibody antibody function Antibody Response Antibody titer Antigen binding antibody Combination comparable conserved COVID-19 cross-reactivity disease dose expected Fc-receptors first dose function functional functions humoral immune response hybrid Hybrid immunity immune immune priming Immunity immunization immunodominance increases in indicate individual individuals Infection magnitude modify mRNA mRNA vaccination mRNA vaccine mRNA vaccines neutralizing antibody offer Quality receive recent Region remained resulting robust SARS-CoV-2 second dose selective serology shift spike subsequent symptomatic T cell the SARS-CoV-2 the Spike unique vaccination Vaccine vaccine-induced immune response vaccinee Vaccines variants of concern virus while [DOI] 10.1128/mbio.01647-22 PMC 바로가기
Immunogenicity, efficacy, and safety of SARS-CoV-2 vaccine dose fractionation: a systematic review and meta-analysisArticle Published on 2022-10-252022-11-15 Journal: BMC Medicine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] accelerate Characteristics clinical trial coronavirus disease Coverage COVID-19 COVID-19 vaccine cross-reactivity dose Dose fractionation effective Efficacy Evidence groups immunogenicity induce Meta-analysis mRNA NAb neutralizing antibody omicron predicted profile protein subunit vaccine reported Safe Safety safety profile SARS-CoV-2 vaccine Seroconversion Standard dose strain systematic review T cell T cell responses the vaccine Vaccine variant variants [DOI] 10.1186/s12916-022-02600-0 PMC 바로가기
Reduced B cell antigenicity of Omicron lowers host serologic responseArticle Published on 2022-10-182022-11-15 Journal: Cell Reports [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Antibody Response Antibody titer antigenicity B cell Breakthrough infection common cold coronavirus computational structural biology conserved CP: Immunology CP: Microbiology cross-reactivity deep learning ELISA Epitopes evade explain feature geometric Host Infection less Lower mechanism Mice immunization experiment mutated Neutralizing omicron Omicron variant of concern RBD RBS Receptor binding Receptor binding domain receptor binding site reduced reduction reduction in reveal SARS-CoV-2 Serologic response serological response serum Spike protein trajectory vaccine-induced antibody variant variants viral evolution [DOI] 10.1016/j.celrep.2022.111512 PMC 바로가기
Discriminating cross-reactivity in polyclonal IgG1 responses against SARS-CoV-2 variants of concernArticle Published on 2022-10-152022-11-15 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Anti-spike antibody antibody cross-reactivity antigens approach Beta clone clones cross-reactivity discriminatory power Diseases Donor exhibit Gamma IgG1 IgG1 antibodies IgG1 response individual donor Infection lack MONITOR observation plasma plasma IgG1 polyclonal profile Protein recognize response responses SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 variant Spike protein Support the SARS-CoV-2 trimer variant virus Virus neutralization VoC VOCs wild type Wuhan [DOI] 10.1038/s41467-022-33899-1 PMC 바로가기
Differential patterns of cross-reactive antibody response against SARS-CoV-2 spike protein detected for chronically ill and healthy COVID-19 naïve individualsArticle Published on 2022-10-072022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, 치료제, [키워드] Affect Alter antibody Antibody Response Antigen antigen exposure antigenic B.1.1.529 boost chronic conditions chronic infection clinical history Cohort COVID-19 COVID-19 pandemic cross-reactive cross-reactive antibody cross-reactivity defined described detectable Diseases epitope glycoprotein healthy high mutation rate highly antigenic immune response immunogenic individual mechanism mutations naïve individual neurological omicron overlapped Pathogens resolved SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 S1 SARS-CoV-2 spike protein serum antibody severe COVID-19 specificity Spike protein Subsequent infection target the antibody response understanding vaccination variants of SARS-CoV-2 Viral antigen virus viruses [DOI] 10.1038/s41598-022-20849-6 PMC 바로가기
Humoral cross-coronavirus responses against the S2 region in children with Kawasaki diseaseArticle Published on 2022-10-012022-11-15 Journal: Virology [Category] COVID19(2023년), SARS, 진단, [키워드] antibodies antibody approach children Control Coronary Coronary aneurysms coronavirus correlated CoV CoVs Cross-immunity cross-reactive cross-reactivity effort explain feature febrile humoral Immunity Infection Inflammatory Kawasaki disease MIS-C multisystem inflammatory syndrome in children OC43 pathology Protein raise reactivity recent Region responses against Safe SARS CoV-2 SARS-CoV-2 SARS-CoV-2 S2 shown Support syndrome the Spike Vaccine vascular inflammation [DOI] 10.1016/j.virol.2022.08.010 PMC 바로가기