cytokine level – Page 3 – Communicable Diseases Research

T cell counts and IL-6 concentration in blood of North African COVID-19 patients are two independent prognostic factors for severe disease and death

북아프리카 COVID-19 환자의 혈액 내 T 세포 수와 IL-6 농도는 심각한 질병 및 사망에 대한 두 가지 독립적인 예후 인자입니다

Article

Published on 2022-01-012022-09-11
Journal: Journal of leukocyte biology [Category] 바이오마커,

The Possible Role of Bruton Tyrosine Kinase Inhibitors in the Treatment of COVID-19: A Review

Review article

Published on 2021-12-152022-10-05
Journal: Current Therapeutic Research [Category] 바이오마커, 변종, 치료법,

[키워드] anti-inflammatory cytokines Anti-inflammatory effects Bruton tyrosine kinase inhibitor BTK BTK inhibitor caused Clin clinician Complication Coronavirus disease 2019 COVID-19 cytokine level Cytokine release syndrome Cytokines develop disease Effect Effectiveness Elsevier evaluate Exp immune response Inflammation Inflammatory cytokines information journal kinase less management medication Mortality Novel coronavirus objective pandemic Pathogenesis pathogenesis of COVID-19 pathway Patient patients patients with COVID-19 provide receiving reduce Result review role SARS-CoV-2 Serum level Severe case severe respiratory illness Signaling Spread subsequent Support the disease treating COVID-19 Treatment tyrosine Web of Science
[DOI] 10.1016/j.curtheres.2021.100658 [Article Type] Review article

Serial measurement of cytokines strongly predict COVID-19 outcome

Research Article

Published on 2021-12-022022-10-28
Journal: PLoS ONE [Category] COVID-19,

Clinical investigation of intestinal fatty acid-binding protein (I-FABP) as a biomarker of SARS-CoV-2 infection

SARS-CoV-2 감염의 바이오마커로서의 장지방산결합단백(I-FABP)의 임상적 조사

Article

Published on 2021-12-012022-09-11
Journal: International Journal of Infectious Diseases [Category] 바이오마커,

[키워드] Admission Biomarker Brazil C-reactive protein characteristic clinical Clinical characteristics collected Concentration correlation COVID-19 COVID-19 disease COVID-19 disease severity COVID-19 patient COVID-19 patients Critically ill Critically ill patient critically ill patients cytokine cytokine level cytokine levels Cytokines damage demonstrated disease severity enrolled Enterocyte enterocytes epithelial cells exacerbated exhibit fatty Fatty acid gastrointestinal tract Hospital stay hospitalisation IL-6 Illness severity infected patient infected patients Inflammation Inflammatory response interferon interleukin interleukin-6 intestinal intestinal epithelial cells intestinal epithelial cells. Laboratory laboratory findings lesion lesions less nonsurvivor nonsurvivors Patient plasma poor prognosis Prognosis Protein receiver operating characteristic receiver operating characteristic curve recorded SARS-CoV-2 SARS-COV-2 infection suggested Urine
[DOI] 10.1016/j.ijid.2021.09.051 PMC 바로가기 [Article Type] Article

Assessing the potential correlation of polymorphisms in the IL6R with relative IL6 elevation in severely ill COVID-19 patients’

중증 COVID-19 환자에서 IL6R의 다형성과 상대적 IL6 상승의 잠재적 상관 관계 평가

Clinical Trial

Published on 2021-12-012022-09-11
Journal: Cytokine [Category] 바이오마커, 변종, 임상,

[키워드] Affect affecting Analysis Assessing association baseline Baseline assessment baseline level blood sample Blood samples clinical response Clinical studies clinical study clinical variable collected Combination Control correlation COVID-19 COVID-19 patient COVID-19 patients COVID19 COVID19 patients cytokine level cytokine levels Cytokine storm defined determine elevated Elevation Genetic Genetic variant genetic variants Glucose help highest hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient hospitalized patients identify IL-6 IL-6 inhibition IL-6 level IL-6 levels IL6 IL6R interleukin-6 Interpretation mild COVID-19 patient Mortality norm not seen outcome oxygen P-value p-value < 0.01 Participants pathophysiology patient population patients Phase 3 Placebo plasma Plasma levels Pneumonia polymorphism randomized study receiving Regulatory report robust rs2228145 Sequencing analysis serum severe and mild COVID-19 patients severe COVID-19 severe patients severity shown significantly significantly increased supplemental oxygen support tested the patient tradipitant Treatment unlikely variant variants were measured while WHO whole genome Whole genome sequencing
[DOI] 10.1016/j.cyto.2021.155662 PMC 바로가기 [Article Type] Clinical Trial

Severe manifestations and treatment of COVID-19 in a transplanted patient with Fabry disease

Case report

Published on 2021-12-012022-10-05
Journal: Molecular Genetics and Metabolism Reports [Category] 변종, 유전자 메커니즘, 치료법,

[키워드] addition affected aspergillosis Autopsy bronchopulmonary aspergillosis Case report caused complex Complication COVID-19 COVID-19 infection current cytokine level Cytokines Diabetes Mellitus dialysis disease elevated ERT Fabry disease fibrosis GLA greater Health individual Interstitial nephritis invasive kidney kidney transplant late stage male management manifestation Manifestations membrane Migalastat pathogenic variant Patient patients Pneumonia presence of comorbidities Probability progression prothrombotic state rapid increase renal renal system Research Respiratory failure risk severity shown the disease therapy Transplant treated Treatment with COVID-19
[DOI] 10.1016/j.ymgmr.2021.100802 [Article Type] Case report

Critically Ill Coronavirus Disease 2019 Patients Exhibit Hyperactive Cytokine Responses Associated With Effector Exhausted Senescent T Cells in Acute Infection

Article

Published on 2021-11-222022-11-15
Journal: The Journal of Infectious Diseases [Category] SARS, 바이오마커,

437. Longitudinal Plasma Cytokine Profiles Differentiating COVID-19 Severity Groups

Poster Abstracts

Published on 2021-11-042022-10-29
Journal: Open Forum Infectious Diseases [Category] COVID-19,

[키워드] acute COVID-19 acute respiratory syndrome age analyzed assigned association Asymptomatic blood sample cause children Clinical severity cohorts consultant convalescent convalescent plasma coronavirus coronavirus disease COVID-19 criteria CSS cytokine cytokine level cytokine profile Cytokine storm syndrome Disease progression elevated enrolled figure GCSF group hospital Hospitalization Hospitalized IL-10 IL-15 IL-8 Inc Infection Inflammatory Inflammatory response IP-10 Joshua less longitudinal Mild mild cases MIP-1β MIS-C moderate moderate-severe nothing participant Participants Patient PCR Phenotypes plasma sample polymerase chain positive profile Prospective Quantitative response Result SARS-CoV-2 SARS-CoV-2 PCR severe cases severe COVID-19 severe group Severe patient severity Severity Score significant difference syndrome Temporal tested Thomas timepoint timepoints Treatment Wolf
[DOI] 10.1093/ofid/ofab466.636 PMC 바로가기 [Article Type] Poster Abstracts

Can the Cytokine Profile According to ABO Blood Groups Be Related to Worse Outcome in COVID-19 Patients? Yes, They Can

ABO 혈액형에 따른 사이토카인 프로필이 COVID-19 환자의 더 나쁜 결과와 관련될 수 있습니까? 네, 그들은 할 수 있어요

Immunology

Published on 2021-10-132022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커,

[키워드] 95% CI ABO ABO blood groups Admission Analysis association Biomarker Blood Group Can collected coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients cytokine cytokine level cytokine levels cytokine profile cytokine release Cytokines death disease group growth factor hepatocyte hepatocyte growth factor Hospital admission hospital ward intensive care intensive care unit intubation log maintenance mechanical ventilation Mortality mortality risk outcome Patient plasma sample plasma samples Prevalence profile Prognosis recruited risk severity statistically significant suggested
[DOI] 10.3389/fimmu.2021.726283 PMC 바로가기 [Article Type] Immunology

In-Depth Investigation of Conjunctival Swabs and Tear Fluid of Symptomatic COVID-19 Patients, an Observational Cohort Study

COVID-19 증상 환자의 결막 면봉 및 눈물액에 대한 심층 조사, 관찰 코호트 연구

Observational Study

Published on 2021-10-042022-09-11
Journal: Translational vision science & technology [Category] SARS, 임상, 치료기술,

[키워드] analyzed Chain Reaction Conjunctiva conjunctival Conjunctival swab conjunctival swabs correlation COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients Ct values cycle cycle threshold cytokine cytokine level Cytokines determine disease onset elevated examined first visit healthcare worker Healthcare workers healthy control healthy controls hospitalized COVID-19 patient identify IL-1β IL-6 immunoassays investigation laboratory-confirmed large cohort majority multicenter multiplex Nasopharyngeal swab nasopharyngeal swabs nasopharynx Next-generation sequencing no correlation ocular Ocular surface performed Phylogenetic analysis polymerase chain polymerase chain reaction positive reverse transcription reverse transcription polymerase chain reaction risk SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 viral RNA Sequencing Sequencing analysis significantly higher specimen Swab symptomatic Tear threshold tissue tropism viral strain viral strains virus strain
[DOI] 10.1167/tvst.10.12.32 PMC 바로가기 [Article Type] Observational Study