Antibody Response Induced by BNT162b2 and mRNA-1273 Vaccines against the SARS-CoV-2 in a Cohort of Healthcare Workers의료 종사자 집단에서 SARS-CoV-2에 대한 BNT162b2 및 mRNA-1273 백신에 의해 유도된 항체 반응Article Published on 2022-06-072022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] age analyzed anti-S antibodies antibody Antibody Response Arterial hypertension BMI BNT162b2 body mass body mass index clinical clinical variables Cohort confounders confounding factors Elecsy Elecsys healthcare Healthcare workers humoral immunogenicity hypertension individual induced infected with SARS-CoV-2 Infection levels of antibody lowest medians mRNA mRNA vaccine mRNA vaccines mRNA-1273 mRNA-1273 vaccine N protein non-infected nucleocapsid preserved Protein response Roche Diagnostics S protein SARS-CoV-2 SARS-COV-2 infection serology serum sample serum samples smoking subject subjects Switzerland the antibody response the S protein the SARS-CoV-2 U/mL uninfected vaccination Vaccine variable worker [DOI] 10.3390/v14061235 PMC 바로가기 [Article Type] Article
Validation of Serological Methods for COVID-19 and Retrospective Screening of Health Employees and Visitors to the São Paulo University Hospital, BrazilCOVID-19에 대한 혈청학적 방법의 검증 및 브라질 상파울루 대학 병원을 방문하는 의료진 및 방문객에 대한 후향적 검사Article Published on 2022-06-022022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] antigens approach Brazil Clinical studies collected country COVID-19 Critical diagnostic diagnostic test diagnostic tests ECLIA Elecsy Elecsys electrochemiluminescence immunoassay ELISA employee enzyme enzyme-linked immunosorbent assays epidemiological gold gold standard Health health employees house immunoassay in-house ELISA in-house ELISAs infection rates neutralization neutralization test nucleoprotein portion Receptor binding domain Recombinant protein recombinant proteins Roche Diagnostics S1 protein SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 antigens SARS-COV-2 infection SARS-CoV-2 N protein screened Screening screenings sensitivity Sensitivity and specificity serological assays serological test Serological tests serology serum sample serum samples specificity Surveillance the S1 protein the SARS-CoV-2 university university hospital vaccinated individual vaccinated individuals validation virus neutralization test Visitor was used [DOI] 10.3389/fcimb.2022.787411 PMC 바로가기 [Article Type] Article
Antibody response to mRNA SARS-CoV-2 vaccination in 182 patients after allogeneic hematopoietic cell transplantation동종 조혈 세포 이식 후 182명의 환자에서 mRNA SARS-CoV-2 백신 접종에 대한 항체 반응Article Published on 2022-06-012022-09-12 Journal: Transplant infectious disease : an official journa [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Allogeneic Allogeneic hematopoietic cell transplantation Antibody titer asked Care Cell cell transplantation Characteristics complications disease Elecsy evaluate evaluated excluded Factor follow-up visits high risk identify immune immunosuppressive infection with SARS-CoV-2 initial Lymphocyte count majority malignancy mRNA mRNA vaccination mRNA vaccine Patient patient cohort patients post-transplant care. Previous studies proportion risk factor Roche SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination Sex significantly Stem cell transplantation therapy Treatment trials U/mL underlying disease vaccination vaccination efficacy was measured while [DOI] 10.1111/tid.13828 PMC 바로가기 [Article Type] Article
Performance of the FREND™ COVID-19 IgG/IgM Duo point-of-care test for SARS-CoV-2 antibody detectionSARS-CoV-2 항체 검출을 위한 FREND™ COVID-19 IgG/IgM Duo 현장 진료 테스트의 성능Article Published on 2022-06-012022-09-11 Journal: Acta clinica Belgica [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome analyzed anti-SARS-CoV-2 assays automated Combination comparable COVID-19 COVID-19 pandemic COVID-19 symptom COVID-19 symptoms Cross reactivity dependent on diagnostic different time point different time points Elecsy IgG IgG/IgM IgM IgM/IgG immune response immunoassay multiple serological assay multiple serological assays onset of symptom PCR-confirmed performance POCT point of care point-of-care point-of-care testing reached respiratory Roche Diagnostics SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 positive patient sensitivity Serological testing serum serum sample serum samples Severe acute respiratory syndrome symptom onset time interval [DOI] 10.1080/17843286.2021.1940776 PMC 바로가기 [Article Type] Article
SARS-CoV-2 seroprevalence and determinants of infection in young adults: a population-based seroepidemiological studySARS-CoV-2 혈청 유병률 및 젊은 성인의 감염 결정 요인: 인구 기반 혈청 역학 연구Article Published on 2022-06-012022-09-11 Journal: Public health [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] 95% confidence interval Adults antibody status calculated conducted confirmed COVID-19 case COVID-19 COVID-19 case COVID-19 infection COVID-19 infections Descriptive statistics determinant determinants effort Elecsy Elecsys Evidence Germany Health authority heterogeneity immunoassay individual individuals Infection infections information media men moderate MOST much higher Odds ratio Odds ratios Participants populations Prevalence prevalent profile public health reported risk SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 seroprevalence Seropositivity Seroprevalence serum sample serum samples social distancing social media the SARS-CoV-2 young adults [DOI] 10.1016/j.puhe.2022.03.009 PMC 바로가기 [Article Type] Article
Kinetics and Persistence of the Cellular and Humoral Immune Responses to BNT162b2 mRNA Vaccine in SARS-CoV-2-Naive and -Experienced Subjects: Impact of Booster Dose and Breakthrough InfectionsSARS-CoV-2-나이브 및 -경험 대상자에서 BNT162b2 mRNA 백신에 대한 세포 및 체액 면역 반응의 동역학 및 지속성: 추가 용량 및 돌발 감염의 영향Article Published on 2022-05-312022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법, [키워드] administration age analyzed Anti-nucleocapsid antibodies anti-SARS-CoV-2 anti-spike antibodies anti-spike antibody antibodies antibody association Belgium benefit blood sample Blood samples blood sampling BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccine booster booster dose booster doses breakthrough infections cell-mediated immune response cellular cellular and humoral immune response Cellular immune response cellular immune responses collected COVID-19 COVID-19 vaccine DiaSorin dose Elecsy enrolled evaluated greater HCW HCWs Healthcare system healthcare worker Healthcare workers help Human humoral Humoral and cellular immune responses humoral immune response Humoral response IFN-γ IgG immune protection immune response immune responses immunization immunogenicity Impact implication increase in individual level individuals Infection initial Kinetics LIAISON Lymphocytes management mandatory mRNA vaccination mRNA vaccine naïve naïve individuals natural infection Neutralization assay neutralization capacity Neutralizing antibodies pandemic participant Participants Peripheral blood peripheral blood lymphocyte peripheral blood lymphocytes persistence Prevent Prospective Study Qiagen QuantiFERON quantified reduce regimen response SARS- CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination second dose secretion severe COVID-19 significantly higher tested the SARS-CoV-2 triggering understanding university vaccination vaccine dose variant Vero E6 was performed [DOI] 10.3389/fimmu.2022.863554 PMC 바로가기 [Article Type] Article
Heterologous immunization with BNT162b2 followed by mRNA-1273 in dialysis patients: seroconversion and presence of neutralizing antibodies투석 환자에서 BNT162b2에 이어 mRNA-1273으로 이종 면역화: 혈청전환 및 중화항체 존재Article Published on 2022-05-252022-09-12 Journal: Nephrology, dialysis, transplantation : official p [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome Analysis anti-SARS-CoV-2 antibodies antibody BNT162b2 boost booster Cambridge Characteristics Concentration coronavirus COVID-19 cut-off dialysis disease dose Efficacy Elasomeran Elecsy Genscript Germany heterologous immunization high risk Humoral immunity immunoreactivity Immunosuppression Infection Mainz Moderna Mortality mRNA vaccine mRNA-1273 mRNA-1273 booster neutralization Neutralization assay Neutralizing antibodies neutralizing antibody of BNT162b2 Patient patients performed plaque reduction neutralization PRNT receiver receiving renal replacement therapy ROC Roche Diagnostics SARS-CoV-2 SARS-CoV-2 spike Seroconversion surrogate Test the SARS-CoV-2 titre Tozinameran USA vaccination virus-neutralizing was measured was reduced were measured were used while wild-type SARS-CoV-2 York [DOI] 10.1093/ndt/gfac018 PMC 바로가기 [Article Type] Article
Detection of SARS-CoV-2 Nucleocapsid, Spike, and Neutralizing Antibodies in Vaccinated Japanese백신을 접종한 일본인에서 SARS-CoV-2 뉴클레오캡시드, 스파이크 및 중화 항체 검출Article Published on 2022-05-052022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Antibody titers coronavirus correlated detection detection system Efficacy Efficiency Elecsy Elecsys evaluate evaluated Fujirebio healthy subject healthy subjects IgG investigated Japanese Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers nucleocapsid patients with COVID-19 respiratory Roche SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 N sensitivity sera serological test severe acute respiratory syndrome Coronavirus specificity spike vaccination were assessed [DOI] 10.3390/v14050965 PMC 바로가기 [Article Type] Article
Using sero-epidemiology to monitor disparities in vaccination and infection with SARS-CoV-2 Research Published on 2022-05-042022-10-05 Journal: Nature Communications [Category] COVID19(2023년), SARS, 바이오마커, 진단, [키워드] Bayesian clinical Coverage cross-sectional determine Elecsy equity FIVE greater hospital Immunity individual Infection infection risk infection with SARS-CoV-2 interval MONITOR Mortality pandemic Probability provide Roche San Francisco SARS-CoV-2 sera Spread tested the epidemic unique vaccination Vaccine while white [DOI] 10.1038/s41467-022-30051-x [Article Type] Research
Exploratory assessment of serological tests to determine antibody titer against SARS-CoV-2: Appropriateness and limitsSARS-CoV-2에 대한 항체가를 결정하기 위한 혈청학적 검사의 탐색적 평가: 적절성 및 한계Multicenter Study Published on 2022-05-012022-09-11 Journal: Journal of Clinical Laboratory Analysis [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Analysis analyzed antibody Antibody titer Antibody titers appropriateness can be used Definition detect determine diagnostic diagnostic test diagnostic tests effective Effectiveness Elecsy Elecsys evaluated Health highlight IgA immunoassay Immunoglobulin immunoglobulins Infection International international standard International standards laboratory data limit limitation Luminex xMAP multicenter multiplex Multiplex assay multiplicity RBD resulting Roche S1 domain SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 test SARS-CoV-2 tests selected serological serological test Serological tests serum serum sample serum samples Siemen Spike protein Standard subject subjects the SARS-CoV-2 the WHO titer to define vaccination Variability WHO [DOI] 10.1002/jcla.24363 PMC 바로가기 [Article Type] Multicenter Study