Do monogenic inborn errors of immunity cause susceptibility to severe COVID-19?면역의 단일 유전자 선천적 오류가 심각한 COVID-19에 대한 감수성을 유발합니까?Comment Published on 2021-07-152022-09-11 Journal: The Journal of Clinical Investigation [Category] SARS, 변종, 진단, [키워드] cause Complete controls COVID-19 COVID-19 patients described effort Evidence experimental design Factor Genetic genetic susceptibility Genome highlight Hypothesis identify immune Immunity immunological profile loss-of-function Mild monogenic inborn error morbidity and mortality Numerous pathway Patient performed predicted predisposition risk stratification SARS-CoV-2 virus Sequencing severe COVID-19 severe disease susceptibility type I interferon variant [DOI] 10.1172/JCI149459 PMC 바로가기 [Article Type] Comment
Increase of SARS-CoV-2 RNA load in faecal samples prompts for rethinking of SARS-CoV-2 biology and COVID-19 epidemiology대변 샘플에서 SARS-CoV-2 RNA 로드의 증가는 SARS-CoV-2 생물학 및 COVID-19 역학에 대한 재고를 촉구합니다Research Article Published on 2021-07-012022-09-11 Journal: F1000Research [Category] MERS, SARS, 치료기술, [키워드] administration Antibiotics Bacteria Bacterial bacterial culture bacterial cultures Biology biology of SARS-CoV-2 COVID-19 COVID-19 disease COVID-19 patient described Epidemiology experimental design faece Faeces growth growth medium gut microbiota Hypothesis implication in vitro increase infected individuals knowledge microbiota MONITOR observation peptide peptides replicate reported Result SARS-CoV-2 SARS-CoV-2 biology SARS-CoV-2 RNA scientific evidence starting the disease Treatment Viral viral replication virus [DOI] 10.12688/f1000research.52540.3 PMC 바로가기 [Article Type] Research Article
Studying the prominence effect amid the COVID-19 crisis: implications for public health policy decision-making.Brief Report Published on 2021-05-072022-10-31 Journal: F1000Research [Category] COVID-19, MERS, SARS, [키워드] added asked attribute COVID-19 Decision making determine diminishe experimental design Health implication in both group inhibit involved not affect novel coronavirus disease participant priming Prominence effect public health public policy required Result Support tested [DOI] 10.12688/f1000research.27324.2 PMC 바로가기 [Article Type] Brief Report
Peripheral blood microRNAs and the COVID-19 patient: methodological considerations, technical challenges and practice points말초혈액 microRNA와 COVID-19 환자: 방법론적 고려사항, 기술적 과제 및 실천 포인트Review Published on 2021-05-012022-09-11 Journal: RNA Biology [Category] SARS, 바이오마커, 치료기술, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 addressed among others Analysis angiotensin Angiotensin-converting enzyme ARDS Biomarker biopsies Blood circulating circulating miRNA profile circulating miRNA profiles Clinical practice coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 emergency COVID-19 patients detection Early detection experimental design heparin infection with SARS-CoV-2 Interpretation liquid biopsy LMWH low molecular weight low molecular weight heparin management methodological Methods microRNA MicroRNAs miRNA miRNA signature miRNAs ncRNA noncoding RNA pandemic peripheral public health qPCR reproducibility respiratory respiratory distress resulting rigour robust RT-qPCR SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus transcriptomic translation variable [DOI] 10.1080/15476286.2021.1885188 PMC 바로가기 [Article Type] Review
Tissue specificity-aware TWAS (TSA-TWAS) framework identifies novel associations with metabolic, immunologic, and virologic traits in HIV-positive adults조직 특이성 인식 TWAS(TSA-TWAS) 프레임워크는 HIV 양성 성인의 대사, 면역 및 바이러스 특성과의 새로운 연관성을 식별합니다.Research Article Published on 2021-04-262022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Affect affected AIDS Analysis applied association associations assumption Bilirubin bioinformatics CETP cholesterol cholesteryl ester clinical complex contribute current dataset enzyme eQTLs error rate evaluate experimental design expressed expression expression quantitative trait loci False positive Gene Expression Genes greater group High-density lipoprotein High-density lipoprotein cholesterol highlighting identify Laboratory loci mechanisms methodology multiple tissues novel association plasma pleiotropic gene power previous study promote Protein provide Quantitative regulated Regulatory replicated Research robust specificity statistical tissue tissues total bilirubin total bilirubin levels traits transcriptional transcriptionally transcriptome-wide transfer Triglyceride type I type I error UGT1A1 uridine uridine diphosphate variety Viral Viral load [DOI] 10.1371/journal.pgen.1009464 PMC 바로가기 [Article Type] Research Article
Cardiopulmonary resuscitation (CPR) training strategies in the times of COVID-19: a systematic literature review comparing different training methodologiesReview Published on 2021-03-292022-10-29 Journal: Scandinavian Journal of Trauma, Resuscitation and [Category] Coronavirus, SARS, [키워드] Algorithm Alternative CPR training alternative method article assessment Basic life support (BLS) Cardiopulmonary resuscitation Chest COVID-19 pandemic CPR CPR training methodologies effective experimental design Final Google Scholar help Hybrid CPR training inclusion criteria independent knowledge layperson literature review methodology moderate Online CPR training outcome performed Practice Public Quality researchers Result screened searched ST group Standard CPR training Traditional trainee Ventilation Volume was used [DOI] 10.1186/s13049-021-00869-3 PMC 바로가기 [Article Type] Review
Influence of a COVID-19 vaccine’s effectiveness and safety profile on vaccination acceptanceRandomized Controlled Trial Published on 2021-03-092022-10-05 Journal: Proceedings of the National Academy of Sciences of [Category] 임상, [키워드] absence benefit conducted conjoint analysis coronavirus COVID-19 COVID-19 pandemic COVID-19 vaccine Decision analysis Effect effective Effectiveness Efficacy expected experimental design Factor Factors Fever influence Interaction interaction effect likelihood National outcome permanent paralysis Probability receiving remained Replication reported Safe safety profile serious adverse reaction Serious adverse reactions Side effect Side effects significant effect significant increases in significantly the vaccine vaccination Vaccine Vaccine acceptance [DOI] 10.1073/pnas.2021726118 PMC 바로가기 [Article Type] Randomized Controlled Trial
An Egocentric Network Contact Tracing Experiment: Testing Different Procedures to Elicit Contacts and PlacesArticle Published on 2021-02-042023-06-12 Journal: International Journal of Environmental Research an [Category] MERS, [키워드] Contact tracing ego networks experimental design field theory social networks [DOI] 10.3390/ijerph18041466 PMC 바로가기 [Article Type] Article
Evaluating contaminated dental aerosol and splatter in an open plan clinic environment: Implications for the COVID-19 pandemic개방형 클리닉 환경에서 오염된 치과용 에어로졸 및 튀김 평가: COVID-19 전염병에 대한 시사점Article Published on 2021-02-012022-09-11 Journal: Journal of dentistry [Category] Coronavirus, 치료기술, [키워드] aerosol Aerosols appear benefit clinic clinical Clinical significance clinics conditions Contamination COVID-19 pandemic dental Dental equipment Dental fallow time Dental high-speed equipment Dental infection control dental procedures detectable distribution Effect Evaluating experimental design Filter Paper filter papers Fluorescein fluorescein dye head Infection majority mannequin medium MOST mouth open produced reduced retained risk SARS-CoV-2 suction Ventilation Volume was used water [DOI] 10.1016/j.jdent.2020.103565 PMC 바로가기 [Article Type] Article
Development, optimization and characterization of nanoemulsion loaded with clove oil-naftifine antifungal for the management of tinea클로브 오일-나프티핀 항진균제가 함유된 나노에멀전의 개발, 최적화 및 특성화로 티니아 관리하기Research Article Published on 2021-02-012024-07-28 Journal: Drug Delivery [Category] 백선증, [키워드] Box–Behnken clove oil experimental design naftifine Nanoemulsion tinea [DOI] 10.1080/10717544.2021.1879314 PMC 바로가기 [Article Type] Research Article