Advanced Liver Fibrosis Correlates With Impaired Efficacy of Pfizer-BioNTech COVID-19 Vaccine in Medical Employees진행성 간 섬유증은 의료진에서 화이자-바이오엔텍 코로나19 백신의 효능 저하와 상관관계가 있습니다Article Published on 2022-06-012022-09-12 Journal: Hepatology communications [Category] MERS, 진단, [키워드] acute respiratory syndrome age booster calculated candidate center chronic liver disease coronavirus coronavirus disease correlated COVID-19 COVID-19 vaccine displaying Efficacy employee Factor FIB-4 fibrosis Fibrosis-4 Gender General population hepatic fibrosis IgG IgG level IgG titer Immunoglobulin Immunosuppressed Impaired Increased individual Jerusalem male males offered Older age Pfizer-BioNTech provide Responder risk factor significantly subgroups Undetermined vaccination Vaccine Vaccine failure vaccine response weakened [DOI] 10.1002/hep4.1901 PMC 바로가기 [Article Type] Article
Impaired Vagal Activity in Long-COVID-19 PatientsArticle Published on 2022-05-132022-11-16 Journal: Viruses [Category] 치료기술, [키워드] activity Analysis autonomic components correlated COVID-19 patients D-dimer detect develop Dysautonomia dysautonomia hypothesis dysfunction ECG elevated explain heart rate variability Hypothesis Impaired impairment increase increase in increased risk Intervention Long long-COVID-19 Mortality Multiorgan dysfunction multivariable analysis Myocardial nervous system NT-proBNP Patient patients persistence power procoagulative state. prothrombotic state readmission significantly significantly higher Symptom Vagal Variability [DOI] 10.3390/v14051035 PMC 바로가기
Impaired immune responses in blood cancers improved by third COVID-19 vaccine dose News & Views Published on 2022-05-112022-10-05 Journal: Nature cancer [Category] COVID19(2023년), SARS, 임상, 치료법, [키워드] Blood Cancer COVID-19 vaccine dose immune response Impaired [DOI] 10.1038/s43018-022-00369-y [Article Type] News & Views
Cold agglutinin disease secondary to severe SARS-CoV-2 treated with eculizumab에쿨리주맙으로 치료한 중증 SARS-CoV-2에 따른 한랭응집소 질환Case Reports Published on 2022-04-292022-09-12 Journal: BMJ case reports [Category] COVID19(2023년), SARS, 진단, [키워드] acute renal failure acute respiratory distress adult intensive care antibody Cold agglutinin disease COVID-19 Critical died Direct antiglobulin test disease Diseases eculizumab explained French haematology (drugs and medicines) immune response immunological disorder Impaired Infectious diseases Inflammation Intensive intensive care life-threatening monoclonal Occurrence Patient persistent positive reported resolved SARS-COV-2 infection severe coronavirus disease Severe COVID-19 Infection severe SARS-CoV-2 specific treatment syndrome the patient therapy titre Transfusion therapy treated [DOI] 10.1136/bcr-2021-242937 PMC 바로가기 [Article Type] Case Reports
A parallel randomised controlled trial of the Hypoglycaemia Awareness Restoration Programme for adults with type 1 diabetes and problematic hypoglycaemia despite optimised self-care (HARPdoc) Research Published on 2022-04-282022-10-05 Journal: Nature Communications [Category] 임상, [키워드] Analysis Anxiety Attitude avoidance Awareness baseline blinded changes in cognitive conducted Depression diabete difference distress effective emotional Estimated Health Hypothesis Impaired insulin Measures outcome positive Primary outcome randomised randomised controlled trial rate ratio recall reduced reducing restoration risk secondary self-care significantly T1D Treatment Trial Two-arm [DOI] 10.1038/s41467-022-29488-x [Article Type] Research
Multi-Design Differential Expression Profiling of COVID-19 Lung Autopsy Specimens Reveals Significantly Deregulated Inflammatory Pathways and SFTPC Impaired TranscriptionCOVID-19 폐 부검 표본의 다중 디자인 차등 발현 프로파일링은 상당히 규제 완화된 염증 경로 및 SFTPC 손상된 전사를 나타냅니다Article Published on 2022-03-162022-09-11 Journal: Cells [Category] SARS, 유전자 메커니즘, [키워드] Activation Autopsy carried cathepsin Cathepsin C CD163 CFB Clinical diagnosis complement Complement activation controls COVID-19 COVID-19 patient COVID-19-related death CTSC deaths deregulation develop differential expression effective effective therapy FFPE formalin formalin-fixed paraffin-embedded Gene expression profiling had no high viral load IFIT1 immune signature immunohistochemistry Impaired Inflammation ISG15 lung lung damage Macrophage macrophage polarization mechanism MS4A4A Nasopharyngeal swab OAS1 overexpression paraffin pathway pharmacological strategies PKM positive potential therapeutic targets Prevent probe Profiling Protein protein C pulmonary viral quantified required Respiratory disease RNA RNA-Seq RSAD2 SARS-CoV-2 SARS-COV-2 infection selected Seven SFTPC Siglec-1 SIGLEC1 signaling pathway specimen tissue sample tissue samples transcriptomic Transcriptomic profiling type I interferon Viral load were used [DOI] 10.3390/cells11061011 PMC 바로가기 [Article Type] Article
Impaired Humoral Response to Third Dose of BNT162b2 mRNA COVID-19 Vaccine Despite Detectable Spike Protein-specific T cells in Lung Transplant Recipients폐 이식 수혜자에서 스파이크 단백질 특이적 T 세포가 감지되었음에도 불구하고 BNT162b2 mRNA COVID-19 백신 3차 접종에 대한 체액 반응 손상Article Published on 2022-03-012022-09-11 Journal: Transplantation [Category] MERS, SARS, 진단, 치료기술, [키워드] COVID-19 Impaired mRNA of BNT162b2 recipient response spike T cell Transplant [DOI] 10.1097/TP.0000000000004021 PMC 바로가기 [Article Type] Article
COVID-19 vaccination and breakthrough infections in patients with cancerResearch article Published on 2022-03-012022-10-05 Journal: Annals of oncology : official journal of the Europ [Category] SARS, 임상, [키워드] Antibody titer approach Breakthrough infection Cancer Chemotherapy Clinical efficacy clinical feature clinical trial Comorbidity confounders COVID-19 COVID-19 vaccination COVID-19 vaccine develop Evidence excluded Health Hematologic malignancy Immunity Immunosuppression Impaired include less lethal infection malignancy neoplasm outcome outcomes Patient patients Patients with cancer populations PROTECT public health Result risk robust SARS-CoV-2 severe COVID-19 social distancing symptomatic therapy vaccination [DOI] 10.1016/j.annonc.2021.12.006 [Article Type] Research article
CNN-LSTM Hybrid Real-Time IoT-Based Cognitive Approaches for ISLR with WebRTC: Auditory Impaired Assistive TechnologyResearch Article Published on 2022-02-212022-10-31 Journal: Journal of Healthcare Engineering [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] Algorithm Analysis audible sound auditory average Community COVID-19 expressions facial feature globe healthcare help hybrid Impaired impairment individual Internet ISLR means memory platform provided Recognition Research SIGN technology WebRTC [DOI] 10.1155/2022/3978627 PMC 바로가기 [Article Type] Research Article
Impaired detection of omicron by SARS-CoV-2 rapid antigen testsSARS-CoV-2 신속 항원 검사에 의한 오미크론 검출 장애Original Article Published on 2022-02-202022-09-10 Journal: Medical Microbiology and Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 치료기술, 치료법, [키워드] analytical sensitivity Awareness B.1.1.529 B.1.617.2 Cell Cell culture collected comparable country Ct values detection rate diagnostic test driven by dropped evaluated examined globe highest Impaired Infection infection rate infection rates isolate Laboratory lateral flow limit of detection National nine nucleocapsid protein omicron pandemic PCR-negative PCR-positive point-of-care tests positive positive test result Predictive Predictive value ranged rapid antigen test Rapid antigen tests RAT RATs reduced required respiratory RNA copies RNA copy SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 rapid antigen test sensitivity specificity specimen suggested supplementary material swab sample test results the SARS-CoV-2 variant virus load virus stock VoC [DOI] 10.1007/s00430-022-00730-z PMC 바로가기 [Article Type] Original Article