Evaluation of Respiratory Emissions During Labor and Delivery: Potential Implications for Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)Observational Study Published on 2021-10-012022-10-05 Journal: Obstetrics and gynecology [Category] SARS, 임상, [키워드] acute respiratory syndrome breath calculated collected coronavirus coronavirus 2 cough Course emission evaluated faster labor observational study Potential potential for transmission Primary outcome processed produced respiratory risk SARS-CoV-2 tested transmission of SARS-CoV-2 vaginal delivery women [DOI] 10.1097/AOG.0000000000004533 PMC 바로가기 [Article Type] Observational Study
Determinants of Preventive Behaviors for COVID-19 in JapanArticle Published on 2021-09-232022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] addition Affect age Anxiety Behavior carried COVID-19 COVID-19 pandemic death determinant determinants determine Effectiveness Factor Frequency greater group implementation Infection Japan labor Ministry of Health Mortality mortality rate Multiple regression analysis Preventive behavior questionnaire risk Risk perception Welfare [DOI] 10.3390/ijerph18199979 PMC 바로가기 [Article Type] Article
First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol아급성 완전 척수 손상에서 iPSC 유래 NS/PC 이식의 인간 최초 임상 시험: 연구 프로토콜Article Published on 2021-09-072022-09-11 Journal: Regen Ther [Category] 비임상, [키워드] application approach approved breath Cell cell differentiation center clinical clinical study clinical trial clinical trials Committee Complete conducted Consent COVID-19 epidemic dose-escalation effective Efficacy Evidence evidence of experiment follow-up period Good Immunosuppression induced induced pluripotent stem cells inhibitor initial Injury Japan Japanese Kyoto labor life Medicine Ministry of Health Mouse models network Neural Neural stem/progenitor cells neurological function Open-label organized outcomes Patient pluripotent stem cells preclinical study preliminary evidence primary focus promote protocol quality checks receive recruited regenerative medicine registry Safe single-arm design spinal cord Spinal cord injury stock Study protocol transplantation Treatment university Welfare [DOI] 10.1016/j.reth.2021.08.005 PMC 바로가기 [Article Type] Article
The impact of the COVID-19 pandemic on postpartum contraception planningCOVID-19 전염병이 산후 피임 계획에 미치는 영향Article Published on 2021-09-012022-09-11 Journal: American journal of obstetrics & gynecology MFM [Category] SARS, 치료기술, [키워드] 95% confidence interval addition adjusted Admission Affect age Alpha Antenatal approved Asian barrier Birth both groups Care changes in Cohort cohorts conducted Consent Contraception contraindication counseling COVID COVID-19 COVID-19 pandemic current decrease delivery mode demographics dependent on detect discharge discharged effective Effectiveness evaluate figure Final Fisher exact test form Health Organization in both group increase in increasingly individual institutional barrier institutional review board intrauterine device labor majority mandatory maternity median median age not differ offered outcome parity Patient placement plan Poisson regression model prenatal care proportion random Random sample Randomly reduce reduced Relative risk retrospective retrospective cohort study risk risk ratio Sample size secondary Secondary outcomes selected significant decrease Stanford University Sterilization telehealth Telemedicine the median was used white World Health Organization [DOI] 10.1016/j.ajogmf.2021.100412 PMC 바로가기 [Article Type] Article
Development and validation of an in-house, low-cost SARS-CoV-2 detection assay자체 저비용 SARS-CoV-2 검출 분석의 개발 및 검증Article Published on 2021-09-012022-09-11 Journal: Journal of infection and public health [Category] SARS, 치료기술, 치료제, [키워드] Altona Diagnostics Amplicon analyses approach biosafety biosafety level cause coded collected conducted COVID-19 COVID19 develop development diagnostic diagnostic tests evaluated False-positive results GISAID database hand hospital house labor Laboratory level 2 Nasopharyngeal swab Patient PCR PCR assay positive primer Primers protocol R 2 required retrieved RNA RNA extraction RT-PCR RT-PCR assay SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-CoV-2 testing sensitivity Sensitivity and specificity sequenced specificity target gene tested virus was performed [DOI] 10.1016/j.jiph.2021.07.009 PMC 바로가기 [Article Type] Article
Rapid Cycle Implementation and Retrospective Evaluation of a SARS-CoV-2 Checklist in Labor and DeliveryResearch Article Published on 2021-08-062022-10-28 Journal: BMC health services research [Category] COVID-19, MERS, SARS, [키워드] Analysis approach attributes baseline benefit Care characteristic Characteristics checklist Consolidated framework for implementation research COVID-19 COVID-19 outbreak Culture cycle Cycling delivery domain domains effort facilitated facilitator Factor framework healthcare implementation individual information labor Labor and delivery management mapped Obstetric pandemic parturient patients perioperative checklist Rapid reported required Result SARS-CoV-2 supplementary material transitioned was performed [DOI] 10.1186/s12913-021-06787-5 PMC 바로가기 [Article Type] Research Article
Efficient machine learning model for predicting drug-target interactions with case study for Covid-19COVID-19에 대한 사례 연구와 약물-표적 상호 작용을 예측하기위한 효율적인 기계 학습 모델Article Published on 2021-08-012022-08-31 Journal: Computational biology and chemistry [Category] MERS, SARS, 신약개발, 치료기술, 치료제, [키워드] Accuracy ACE2 protein affected Algorithm amino-acid amino-acid sequence applied can be used case study chemical properties computational method Corona virus Corona viruses COVID-19 COVID-19 infection cross dataset datasets Deep-learning develop drug drug treatment drug treatments drug-target interaction Drug-target interactions DrugBank drugs Effect effective efficient Ensemble learning experiment Experimental result experimental results f-score feature Infection input Interaction interactions labor labor-intensive Laboratory LINE machine machine learning performed physical physical and chemical properties predict predicted prediction Protein protein sequence protein sequences Proteins Structure structures System target time-consuming viruses [DOI] 10.1016/j.compbiolchem.2021.107536 PMC 바로가기 [Article Type] Article
Lyophilization of premixed COVID-19 diagnostic RT-qPCR reactions enables stable long-term storage at elevated temperature사전 혼합된 COVID-19 진단 RT-qPCR 반응의 동결건조는 고온에서 안정적인 장기 보관을 가능하게 합니다Article Published on 2021-07-012022-09-11 Journal: Biotechnology Journal [Category] SARS, 치료기술, [키워드] ambient ambient temperature Cell-free Chain Reaction cornerstone COVID-19 COVID-19 diagnostics COVID-19 outbreak detect diagnostic diagnostic test diagnostic testing diagnostic tests Dilution dilutions elevated temperature eliminating IMPROVE incorporation labor lyophilization maintain Outbreaks point-of-care polymerase chain polymerase chain reaction qPCR quantitative polymerase chain reaction reaction Reactions reduce reducing RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA sensitivity storage Strategy Synthetic biology temperature tested [DOI] 10.1002/biot.202000572 PMC 바로가기 [Article Type] Article
Screening of severe acute respiratory syndrome coronavirus-2 infection during labor and delivery using polymerase chain reaction and immunoglobulin testing중합효소연쇄반응과 면역글로불린 검사를 이용한 분만 중 중증급성호흡기증후군 코로나바이러스-2 감염 검사Article Published on 2021-04-152022-09-11 Journal: Life sciences [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Admission Asymptomatic Chain Reaction coronavirus Coronavirus 2019 coronavirus disease Coronavirus-2 COVID-19 Evidence evidence of groups hospital Hospital admission Immunoglobulin Immunoglobulin G immunoglobulins Infection intensive care intensive care unit labor Labor and delivery Laboratory Maternal mild clinical symptom mild clinical symptoms mother Newborn no significant difference no significant differences on admission outcome outcomes PCR PCR test polymerase chain polymerase chain reaction positive PCR pregnant women Prevalence required respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 PCR screened Screening serological test serum immunoglobulin serum immunoglobulins Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 Spanish women [DOI] 10.1016/j.lfs.2021.119200 PMC 바로가기 [Article Type] Article
Downregulation of type III interferons in patients with severe COVID‐19Observational Study Published on 2021-04-132022-10-04 Journal: Journal of medical virology [Category] MERS, SARS, 바이오마커, 임상, [키워드] Admission alteration C‐reactive protein Characteristics chemokine conducted Coronavirus disease 2019 COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 cytokine disease disease severity ferritin fibrinogen group hospital IFN‐lambda indicated Japan knowledge labor lactate dehydrogenase Mild Ministry of Health pathophysiology Patient Protein reduced SARS‐CoV‐2 serum serum cytokine severe group severity significantly higher significantly lower single center the disease the patient two groups type III interferon Welfare [DOI] 10.1002/jmv.26993 PMC 바로가기 [Article Type] Observational Study