myeloid cells – Page 3 – Communicable Diseases Research

Single-Cell Analysis Reveals the Immune Characteristics of Myeloid Cells and Memory T Cells in Recovered COVID-19 Patients With Different Severities

Immunology

Published on 2022-01-032022-11-01
Journal: Frontiers in Immunology [Category] COVID-19,

sTREM-1 Predicts Disease Severity and Mortality in COVID-19 Patients: Involvement of Peripheral Blood Leukocytes and MMP-8 Activity

STREM-1은 COVID-19 환자의 질병 중증도 및 사망률을 예측합니다 : 말초 혈액 백혈구 및 MMP-8 활동의 관여

Article

Published on 2021-12-152022-08-31
Journal: Viruses [Category] SARS, 바이오마커,

[키워드] activity Biomarker Characteristics clinical Clinical data coronavirus coronavirus disease correlated COVID-19 COVID-19 positive patient Critical death disease enrolled evaluated expressed expression groups IL-10 IL-6 IL-8 immunoassays indicated Inflammation inflammatory mediator inflammatory parameters Inflammatory response inflammatory signals intrinsic investigated Involvement lymphocyte lymphocyte counts matrix metalloproteinase matrix metalloproteinases mediator medical records Mild MMP-8 moderate Mortality MOST myeloid cells myeloid cells-1 neutrophil neutrophil counts outcome Patient patients with COVID-19 peripheral Peripheral blood peripheral blood cells pharmacological intervention pharmacological interventions plasma Plasma level Plasma levels positive correlation positive patients Predictive profile quantification severe disease severity severity of COVID-19 significant negative correlation significantly significantly higher sTREM-1 systemic the timing uncontrolled was related
[DOI] 10.3390/v13122521 PMC 바로가기 [Article Type] Article

Diabetes and susceptibility to infections: Implication for COVID-19

당뇨병과 감염에 대한 감수성: COVID-19에 대한 시사점

Review

Published on 2021-11-012022-09-11
Journal: Immunology [Category] SARS, 바이오마커, 유전자 메커니즘,

[키워드] activating binding Cell cell survival contribute COVID-19 COVID-19 infections diabete diabetes Diabetic differentiation dysregulated explain Factor healthcare immune immune activation Immune cell immune cells immune checkpoint blocker immune response immune-related genes in viral Infection infections Inflammation insulin insulin receptor insulin resistance involved lymphocyte Lymphocytes mechanism mTOR myeloid cell myeloid cells nucleus observation outcome pathology pathway Pathways peripheral tolerance PI3K polarization Proteins receptor regulate shown survival susceptibility susceptibility to infection the strongest Transcription translocate Viral viral infections
[DOI] 10.1111/imm.13383 PMC 바로가기 [Article Type] Review

Targeting Macrophage Dysregulation for Viral Infections: Novel Targets for Immunomodulators

Immunology

Published on 2021-11-012022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS,

[키워드] activated Activation Antiretroviral therapy ART cardiovascular disease CD4+ cell death cells Central nervous system Chikungunya CNS co-morbidity Comorbidities Comorbidity CVD Disease progression driving dysregulation event HIV-1 Human immunodeficiency virus immune dysregulation immunomodulators immunomodulatory Infection Inflammation Influenza initial Macrophage myeloid cell myeloid cells Neurological deficit novel Pathogenesis persist persistence PLWH resulting SARS-CoV-2 survival systemically target targeting tissue undergo viral infection viral infections viral replication kinetics Viral reservoir viruses
[DOI] 10.3389/fimmu.2021.768695 PMC 바로가기 [Article Type] Immunology

Plasma Gradient of Soluble Urokinase-Type Plasminogen Activator Receptor Is Linked to Pathogenic Plasma Proteome and Immune Transcriptome and Stratifies Outcomes in Severe COVID-19

가용성 Urokinase-Type Plasminogen Activator Receptor의 혈장 구배는 병원성 Plasma Proteome 및 면역 전사체와 연결되어 심각한 COVID-19의 결과를 계층화합니다

Immunology

Published on 2021-10-282022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 임상,

[키워드] 95% confidence interval Activation acute respiratory distress acute respiratory distress syndrome Analysis analyzed ARDS benefit Biomarker caused characteristic circulating Clinical outcome clinical outcomes coagulation disorder coagulation disorders Cohort complement Complement activation coronavirus COVID-19 COVID-19 disease COVID-19 patients Critical care Cutoff cutoff value cytokine Cytokines Cytometry differential expression disease effective expressed faster Flow flow cytometry Gradient hazard ratio hyper-inflammation hypercoagulable Hypercoagulable state hyperinflammation immune mass spectrometry morbidity and mortality Mortality myeloid cell myeloid cells Next-generation sequencing Odds ratio operator pathogenic patient cohort performed Peripheral blood peripheral blood cell peripheral blood cells plasma plasma sample plasma samples plasma suPAR Plaur predict Prognosis proteome proteomics receiver receptor respiratory distress risk stratification SARS-CoV-2 coronavirus Sequencing sequencing data severe COVID-19 disease severe COVID-19 patient severe COVID-19 patients Single-cell RNA sequencing soluble uPAR statistical analyses suPAR survival syndrome systemic hyper-inflammation systemic hyperinflammation Transcriptome urokinase Urokinase-Type Plasminogen Activator was done were measured
[DOI] 10.3389/fimmu.2021.738093 PMC 바로가기 [Article Type] Immunology

Enhanced eosinophil-mediated inflammation associated with antibody and complement-dependent pneumonic insults in critical COVID-19

중요한 COVID-19에서 항체 및 보체 의존성 폐렴 손상과 관련된 향상된 호산구 매개 염증

Article

Published on 2021-10-052022-09-11
Journal: Cell Reports [Category] MERS, SARS, 유전자 메커니즘, 진단,

[키워드] Activation adaptive immune responses addition airway airways antibody Antibody Response biopsy complement Complement activation complexes coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients Critical critical COVID-19 patients Critical disease disease pathogenesis driver enhanced eosinophil evidenced Fcγ receptor FcγR hallmark immune immune complex Immune complexes immune responses Inflammation innate immune responses lung lung biopsies mechanism membrane myeloid cell myeloid cells pandemic Pathogenesis Pneumonia receptor respiratory respiratory specimen respiratory specimens SARS-CoV-2 SARS-COV-2 infection Signaling subsequent T helper vasculature Viral Viral pneumonia
[DOI] 10.1016/j.celrep.2021.109798 PMC 바로가기 [Article Type] Article

SARS-CoV-2 infection: Understanding the immune system abnormalities to get an adequate diagnosis

Review

Published on 2021-10-012022-10-27
Journal: Bosnian Journal of Basic Medical Sciences [Category] Coronavirus, COVID-19, Fulltext, MERS,

SARS-CoV-2 infection: Understanding the immune system abnormalities to get an adequate diagnosis

SARS-COV-2 감염 : 적절한 진단을 받기위한 면역계 이상 이해

Review

Published on 2021-10-012022-09-01
Journal: Bosnian Journal of Basic Medical Sciences [Category] 진단,

SARS-CoV-2 infection: Understanding the immune system abnormalities to get an adequate diagnosis

Review

Published on 2021-10-012022-10-27
Journal: Bosnian Journal of Basic Medical Sciences [Category] COVID-19,

Mild and Asymptomatic COVID-19 Convalescents Present Long-Term Endotype of Immunosuppression Associated With Neutrophil Subsets Possessing Regulatory Functions

경증 및 무증상 COVID-19 회복기 조절 기능을 보유한 호중구 하위 집합과 관련된 면역 억제의 장기 엔도타입 제시

Immunology

Published on 2021-09-292022-09-11
Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술,

[키워드] activated addition affecting Analysis anti-CD3 anti-SARS-CoV-2 Asymptomatic Asymptomatic COVID-19 asymptomatic infection autologous Blood Cancer CD8 Cell Complication Concentration convalescent convalescent sera coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 convalescents described disease elevated endotype enrolled expansion FACS function functions GM-CSF granulocyte-macrophage colony stimulating factor (GM-CSF) Granulocytic granulocytic myeloid-derived suppressor cells (PMN-MDSCs) healthy donor IgG immune response Immunosuppression immunosuppressive Infection inhibit long-COVID low-density low-density neutrophils (LDNs) lymphopenia mAb Mild myeloid cell myeloid cells NDN Neutralizing Neutralizing antibodies neutrophil neutrophil dysfunction Neutrophils normal density neutrophils past PCR test PD-L1 positive result present proliferation Propagation Regulatory responsible SARS-CoV-2 SARS-COV-2 infection serum sample serum samples severe lymphopenia significantly higher subpopulation suppressor cells T cell T cells T-cell tendency These cells was used were used Whole blood
[DOI] 10.3389/fimmu.2021.748097 PMC 바로가기 [Article Type] Immunology