The use of amantadine in the prevention of progression and treatment of COVID-19 symptoms in patients infected with the SARS-CoV-2 virus (COV-PREVENT): Study rationale and designResearch article Published on 2022-05-012022-10-05 Journal: Contemporary clinical trials [Category] COVID19(2023년), SARS, 신약개발, 임상, 치료법, 치료제, [키워드] amantadine antiinflammatory Antiviral Asymptomatic caused clinical clinical condition clinical trial combating complex Course COVID-19 COVID-19 symptom Demonstrating develop diagnosed with COVID-19 disease early treatment Effect Effects Efficacy and safety Hospitalized Hypothesis Infection Intensive long-COVID mortality rate Neurological complication Neurological complications organ dysfunction outcome pandemic Patient patients Placebo Poland positive prevention of COVID-19 progression protocol recruitment reduction in Region Respiratory failure risk factor SARS-COV-2 infection severity subject symptomatic syndrome the disease the SARS-CoV-2 virus therapy Treatment Trial worsening [DOI] 10.1016/j.cct.2022.106755 [Article Type] Research article
Treating the body to prevent brain injury: lessons learned from the coronavirus disease 2019 pandemic뇌 손상을 예방하기 위한 신체 치료: 2019년 코로나바이러스 전염병에서 배운 교훈Review Published on 2022-04-012022-09-11 Journal: Current opinion in critical care [Category] Coronavirus, COVID19(2023년), SARS, 치료기술, [키워드] Brain coronavirus disease COVID-19 discharge Doppler edema Electroencephalography emboli Encephalopathy epileptic Evidence Frontal Hypoxemia infrared spectroscopy Intervention intracranial pressure invasive large vessel Limited management marker morbidity morbidity and mortality near-infrared spectroscopy neurologic Neurological complication Neurological complications Occurrence optic nerve optic nerve sheath oxygen Oxygenation pandemic parameter patients with COVID-19 peripheral oxygen saturation Prevent Pupillometry recent reduce transcranial Doppler treating utility [DOI] 10.1097/MCC.0000000000000917 PMC 바로가기 [Article Type] Review
COVID-19 infection and neurodegeneration: Computational evidence for interactions between the SARS-CoV-2 spike protein and monoamine oxidase enzymesResearch article Published on 2022-02-242022-10-05 Journal: Computational and Structural Biotechnology Journal [Category] 변종, [키워드] ACE2 receptor affinity African B.1.351 Brain Brain amines catalytic activity cause change clinical investigation comparable complex condition contagious coronavirus COVID-19 COVID-19 infection disorder docking early diagnosis Effect enzyme etiology Evidence highlight illness infect infected individuals Interaction kidney Lungs mental health Molecular dynamics simulation molecular dynamics simulations neurodegeneration neurodegenerative Neurological complication Neurotransmitters organ Pathologies pathophysiology Pneumonia Regulation responsible SARS-CoV-2 spike protein South South African B.1.351 variant Spike protein strain substrates the SARS-CoV-2 the spike protein therapeutic interventions variant virus wild type [DOI] 10.1016/j.csbj.2022.02.020 [Article Type] Research article
Acute disseminated encephalomyelitis with bilateral optic neuritis following ChAdOx1 COVID-19 vaccinationCase Report Published on 2022-02-122022-10-27 Journal: BMC Neurology [Category] COVID-19, [키워드] Acute disseminated encephalomyelitis Case report Central nervous system ChAdOx1 ChAdOx1 vaccine clinician Course COVID-19 vaccination Demyelination Diagnosis disease doses Evidence female first dose Immune-mediated imperative Inflammatory intravenous MRI Neurological complication occurred Oxford Astra Zeneca coronavirus disease 2019 vaccine pandemic presenting radiological radiological involvement serological result severe acute respiratory syndrome coronavirus 2 steroid subcortical supplementary material Symptom treated vaccination Vaccines virus Visual evoked potential while [DOI] 10.1186/s12883-022-02575-8 PMC 바로가기 [Article Type] Case Report
Acute disseminated encephalomyelitis with bilateral optic neuritis following ChAdOx1 COVID-19 vaccinationCase Report Published on 2022-02-122022-10-27 Journal: BMC Neurology [Category] Coronavirus, COVID-19, COVID19(2023년), Fulltext, MERS, SARS, [키워드] Acute disseminated encephalomyelitis Case report Central nervous system ChAdOx1 ChAdOx1 vaccine clinician Course COVID-19 vaccination Demyelination Diagnosis disease doses Evidence female first dose Immune-mediated imperative Inflammatory intravenous MRI Neurological complication occurred Oxford Astra Zeneca coronavirus disease 2019 vaccine pandemic presenting radiological radiological involvement serological result severe acute respiratory syndrome coronavirus 2 steroid subcortical supplementary material Symptom treated vaccination Vaccines virus Visual evoked potential while [DOI] 10.1186/s12883-022-02575-8 PMC 바로가기 [Article Type] Case Report
Nutraceuticals in HIV and COVID-19-Related Neurological Complications: Opportunity to Use Extracellular Vesicles as Drug Delivery ModalityReview Published on 2022-01-232022-10-28 Journal: Biology [Category] COVID-19, [키워드] Affect Antiviral Appropriate Bioavailability Brain can be used central nervous system (CNS) comorbid patients Complication conditions COVID-19 COVID-19 infection Critical cross Defense delivery dietary supplement dietary supplements disease disorder disorders drug drug delivery EVs exacerbated exacerbating extracellular vesicle Extracellular vesicles feature higher risk HIV HIV patient HIV/AIDS homing increase in increased risk Infection infections inherent intrinsic mechanism modality Neurological complication neurological problem nutraceutical nutraceuticals opportunity overcome people with HIV plant Prophylaxis reduce reducing SARS-CoV-2 severity shown simple stability therapeutic drug therapy treat Treatment viral infections with COVID-19 with HIV [DOI] 10.3390/biology11020177 PMC 바로가기 [Article Type] Review
The COVID-19 infection in children and its association with the immune system, prenatal stress, and neurological complications어린이의 COVID-19 감염 및 면역 체계, 산전 스트레스 및 신경학적 합병증과의 연관성Review Published on 2022-01-012022-09-12 Journal: International Journal of Biological Sciences [Category] 진단, [키워드] acute respiratory syndrome Alter association blood-brain barrier Brain cause caused children Complication complications coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection Cytokine storm death direct infection effective Encephalopathy Human immune responses immune system immunological Mild MOST myalgia neurological Neurological complication Neurological complications Physiology prenatal problem problems proinflammatory Respiratory disease responses SARS-CoV-2 Severe Acute Respiratory Syndrome Corona Virus severe respiratory disease severe symptom Shortness of breath Stress stroke Symptom Transport Treatment unavailability Viral transmission virus virus entry [DOI] 10.7150/ijbs.66906 PMC 바로가기 [Article Type] Review
Lower Cranial Nerve Palsies in the COVID-19 Pandemic: A 10-Case Series of Intensive Care Unit PatientsObservational Study Published on 2022-01-012022-10-05 Journal: European neurology [Category] SARS, 임상, [키워드] Admission appear association Care conducted COVID-19 cranial etiology France Hospitalization Hypothesis immune dysfunction intensity intensive care intensive care unit intubation involved less limb Lower Lower cranial nerve palsy. multifactorial nerve Neurological complication neurological sign no correlation Occurrence palsy Patient patients retrospective SARS-CoV-2 Sery Severe COVID-19 Infection the patient therapy Toxicity treated university Ventilation virus weakness [DOI] 10.1159/000519226 PMC 바로가기 [Article Type] Observational Study
How Does Severe Acute Respiratory Syndrome-Coronavirus-2 Affect the Brain and Its Implications for the Vaccines Currently in UseReview Published on 2021-12-212022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Affect Angiotensin-converting enzyme 2 (ACE2) blood clot Blood–brain barrier (BBB) Brain condition cross Cytokines Dementia draining lymph node Evidence exhibiting expression good laboratory practice higher risk implication infected with SARS-CoV-2 Infection Inflammation injection Lewy body Lewy body dementia mechanism neurological Neurological complication Neurological symptoms novel coronavirus disease that emerged in 2019 (COVID-19) Parkinson’s disease Parkinson’s disease Patient respiratory SARS-CoV-2 severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) Spike protein the spike protein the vaccine [DOI] 10.3390/vaccines10010001 PMC 바로가기 [Article Type] Review
Persistent IgG anticardiolipin autoantibodies are associated with post-COVID syndrome지속적인 IgG 항카디오리핀 자가항체는 코로나 이후 증후군과 관련이 있습니다.Case Reports Published on 2021-12-012022-09-12 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, [키워드] acute COVID-19 addition anticardiolipin antibodies antiphospholipid antibodies autoantibody Autoimmune reaction coronavirus disease COVID COVID-19 defined explained Factor IgG Immunoglobulin independent Infection Inflammatory Inflammatory response long COVID syndrome nervous system Neurological complication pathophysiological mechanism Patient persistence persistent post-COVID syndrome recovering from COVID-19 severity of COVID-19 suggested Symptom syndrome virus [DOI] 10.1016/j.ijid.2021.09.079 PMC 바로가기 [Article Type] Case Reports