Blood myxovirus resistance protein-1 measurement in the diagnostic work-up of suspected COVID-19 infection in the emergency departmentObservational Study Published on 2022-04-012022-10-04 Journal: Immunity, Inflammation and Disease [Category] 임상, [키워드] Analysis AUC Bacterial infection Biomarker conducted Confirmed COVID-19 infection COVID-19 COVID-19 infection COVID-19 patient cut-off diagnose diagnosing diagnostic diagnostic value diagnostic workup elevated emergency department enzyme evaluate immunoassay IMPROVE MxA Myxovirus Negative predictive value Non-COVID-19 Non-COVID-19 patients Patient patients Positive predictive value Primary outcome prospective observational cohort Protein RT-PCR test sensitivity significantly higher single-center specificity viral infections was determined Whole blood [DOI] 10.1002/iid3.609 PMC 바로가기 [Article Type] Observational Study
Prescribing errors in post – COVID-19 patients: prevalence, severity, and risk factors in patients visiting a post – COVID-19 outpatient clinicObservational Study Published on 2022-03-052022-10-04 Journal: BMC Emergency Medicine [Category] MERS, SARS, 임상, [키워드] 95% CI acute respiratory syndrome Analysis Asthma Awareness calculated can be used Care cause clinical pharmacology Consensus COPD coronavirus coronavirus disease COVID-19 COVID-19 hospitalization COVID-19 patient creating discharge eligible First wave for inclusion healthcare high-risk patient hospital Hospitalization Hospitalized hospitalized patient ICU ICU admission identify increase in independent risk factor medication multivariate Netherlands occurred outpatient clinic pandemic Patient patient population patients Pharmacotherapeutic stewardship prescribing Prescribing errors Prevalence Prevent prospective observational cohort recruited Result resulting risk risk factor SARS-CoV-2 severity supplementary material targeted interventions the SARS-CoV-2 therapy were assessed [DOI] 10.1186/s12873-022-00588-7 PMC 바로가기 [Article Type] Observational Study
Real-world serological responses to extended-interval and heterologous COVID-19 mRNA vaccination in frail, older people (UNCoVER): an interim report from a prospective observational cohort studyObservational Study Published on 2022-03-012022-10-05 Journal: The Lancet. Healthy longevity [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] Abstract Administered administration age anti-RBD Anti-RBD IgG anti-Spike IgG Anti-spike IgG responses antibody Antibody Response antigenicity automated baseline binding antibody unit blood sample BNT162b2 BNT162b2 vaccine boost Canada Care clinical clinically Cohort cohorts collected combinations Comorbidity Concentration COVID-19 COVID-19 mRNA Vaccination COVID-19 vaccine decrease distribution dose doses Effectiveness eligible ELISA enrolled extended-interval first dose fluctuation for inclusion force French Government Heterologous heterologous prime-boost homologous or heterologous individual infected individual Interim Interim report log material Moderna mRNA vaccine mRNA vaccines mRNA-1273 mRNA-1273 vaccine mRNA-based COVID-19 vaccine nucleocapsid protein of BNT162b2 Older participant Participants Pfizer-BioNTech prime and boost prospective observational cohort PROTECT Public reference response SARS-COV-2 infection SARS-CoV-2-specific IgG second dose serological response service significant difference significant increase tested the receptor-binding domain the spike protein timepoint translation Trimeric spike protein university Vaccine vaccine availability vaccine dose Vaccines was done were used [DOI] 10.1016/S2666-7568(22)00012-5 PMC 바로가기 [Article Type] Observational Study
Changes in Stroke Rehabilitation during the Sars-Cov-2 Shutdown in SwitzerlandObservational Study Published on 2022-03-012022-10-05 Journal: Journal of rehabilitation medicine [Category] SARS, 임상, [키워드] activities age Anxiety change COVID-19 decrease Depression Deterioration Effect enrolled Follow-up IMPROVE improvement investigated maintain median neurological observation period outcomes parameter physical physical activity prospective observational cohort Quality of life reduction reduction in rehabilitation reported SARS-COV-2 infection sedentary time significantly stroke subject subjects survivor Switzerland Symptom therapy were assessed [DOI] 10.2340/jrm.v53.1118 PMC 바로가기 [Article Type] Observational Study
Differences in mRNA-1273 (Moderna) and BNT162b2 (Pfizer-BioNTech) SARS-CoV-2 vaccine immunogenicity among patients undergoing dialysis투석 중인 환자의 mRNA-1273(모더나)과 BNT162b2(화이자-바이오엔텍) SARS-CoV-2 백신 면역원성의 차이Observational Study Published on 2022-02-282022-09-11 Journal: CMAJ : Canadian Medical Association journal = jour [Category] COVID19(2023년), SARS, 임상, 치료법, [키워드] anti-RBD Anti-spike anti-spike antibody antibody BNT162b2 Canada characterized conducted Control convalescent convalescent serum dialysis difference dose elicited Hemodialysis humoral immunogenicity Immunoglobulin Immunoglobulin G infected with SARS-CoV-2 Maintenance hemodialysis Moderna mRNA mRNA-1273 nucleocapsid protein Patient Pfizer-BioNTech populations prospective observational cohort reached Receptor binding domain recommendation SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 vaccines second dose second dose of vaccine Serologic response significantly lower Spike protein the median the spike protein Toronto vaccination Vaccine [DOI] 10.1503/cmaj.211881 PMC 바로가기 [Article Type] Observational Study
Long-term efficacy and safety of SARS-CoV-2 vaccination in patients with chronic kidney disease, on dialysis or after kidney transplantation: a national prospective observational cohort studyStudy Protocol Published on 2022-02-052022-10-28 Journal: BMC Nephrology [Category] COVID-19, [키워드] adverse event adverse events Analysis antibodies antibody Antibody Response assessment Breakthrough infection Characteristics Chronic kidney disease CKD contribute control group Course COVID-19 COVID-19 in patient current dialysis effective Efficacy Efficacy and safety Endpoint endpoints Follow-up follow-up period Guidance immune response Impact incidence incidence of COVID-19 kidney kidney transplant recipients Kidney transplantation knowledge lack less methodology monitoring morbidity and mortality Mortality National outcome Patient patient group patient groups patients predict primary endpoint prospective observational cohort questionnaire recent Registered Result Safety SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine secondary severe COVID-19 Stage Study design Study protocol subgroup subject supplementary material therapy Trial vaccination Vaccine virus [DOI] 10.1186/s12882-022-02680-3 PMC 바로가기 [Article Type] Study Protocol
Obstetric and neonatal outcomes after SARS-CoV-2 infection in the first trimester of pregnancy: A prospective comparative study임신 1분기 SARS-CoV-2 감염 후 산과 및 신생아 결과: 전향적 비교 연구Observational Study Published on 2022-02-012022-09-11 Journal: The journal of obstetrics and gynaecology research [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] abortion acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission adverse event antibody Antibody titer APGAR score Asymptomatic Birth Blood Cohort cohort study Composite Cord blood coronavirus coronavirus disease Coronavirus disease-19 COVID-19 defined evaluate events excluded first trimester growth higher risk hospital Hospital admission IgG antibodies Infection intensive care intrauterine growth restriction Maternal membranes Nasopharyngeal swab Neonatal Newborn Obstetric outcome Patient patients Pneumonia positive preeclampsia Pregnancy preterm delivery Primary outcome prospective observational cohort rupture SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus significantly more Stillbirth Symptom symptomatic tested Transmission vertical transmission was performed were recorded women [DOI] 10.1111/jog.15105 PMC 바로가기 [Article Type] Observational Study
Mechanical ventilation for older medical patients in a large tertiary medical care centerObservational Study Published on 2022-02-012022-10-05 Journal: European Geriatric Medicine [Category] COVID19(2023년), SARS, 임상, [키워드] age aging average Care Combination COVID-19 pandemic determine died discharge disease Factor functional help hospital Hospitalization Hospitalized identify increase in internal internal medicine majority Mechanical mechanical ventilation medical record morbidity Mortality Older Older age organ organ injury outcome Patient performed predictor prospective observational cohort study period survival Ventilated ventilated patient Ventilation [DOI] 10.1007/s41999-021-00557-6 PMC 바로가기 [Article Type] Observational Study
Lung Function, Radiological Findings and Biomarkers of Fibrogenesis in a Cohort of COVID-19 Patients Six Months After Hospital DischargeResearch article Published on 2022-02-012022-10-05 Journal: Archivos de bronconeumología [Category] 바이오마커, [키워드] 6 minute-walk test 6-MWT6 minute-walk test 95% CI 95%CI acute respiratory distress syndrome age ARDSacute respiratory distress syndrome Biomarker BMIbody mass index body mass index change changes in Chest CT Chest radiography chronic obstructive pulmonary disease circulating Computed tomography COPDchronic obstructive pulmonary disease Coronavirus disease 2019 correlation COVID-19 COVID-19coronavirus disease 2019 CT scan CTComputed Tomography diffusing capacity for carbon monoxide diffusion discharge discharged patients DLCOdiffusing capacity for carbon monoxide elevated evaluate Factor female Fibrogenesis finding function functional GGOground-glass opacity Ground glass opacity ground-glass opacity HFNChigh flow nasal cannula oxygen high flow nasal cannula oxygen ILDinterstitial lung disease impairment IMVmechanical ventilation Interstitial lung disease involved lesion lung Lung fibrosis matrix metalloproteinases mechanical ventilation MMP1 MMP7 MMPmatrix metalloproteinases mMRCmodified British Medical Research Council modified British Medical Research Council Month multicenter NIVnon-invasive ventilation non-invasive ventilation parenchymal Patient patients with moderate performed Peripheral blood proportion prospective observational cohort pulmonary pulmonary fibrosis Pulmonary function test radiographic assessment of lung edema radiological radiological abnormality RALEradiographic assessment of lung edema respiratory parameters Result reverse transcriptase-polymerase chain reaction RT-PCRreverse transcriptase-polymerase chain reaction SARS-CoV-2 pneumonia SARS-CoV-2severe acute respiratory syndrome coronavirus 2 SARSSevere Acute Respiratory Syndrome sEGFRsoluble epidermal growth factor receptor serum biomarker serum biomarkers Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus 2 Severe COVID-19 pneumonia severe patients Sex soluble epidermal growth factor receptor Survivors vascular endothelial growth factor VEGFvascular endothelial growth factor [DOI] 10.1016/j.arbres.2021.08.014 [Article Type] Research article
Epidemiological, Clinical, and Phylogenetic Characteristics of the First SARS-CoV-2 Transmission in a Nursing Home of Singapore: A Prospective Observational InvestigationMedicine Published on 2022-01-282022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome Asymptomatic B.6 CFR Characteristics clinical conducted coronavirus coronavirus disease COVID-19 diagnosed early phase epidemiological epidemiologically Epidemiology Fatality rate Genomic epidemiology healthcare home household hypertension implicated Infection prevention and control investigation IQR less Lineage median age non-survivor Nursing nursing home pandemic proportion Prospective prospective observational cohort public health SARS-CoV-2 SARS-CoV-2 transmission secondary cases Singapore Survivors symptomatic to define Transmission whole-genome sequencing women [DOI] 10.3389/fmed.2021.790177 PMC 바로가기 [Article Type] Medicine