Protein subunit – Page 3 – Communicable Diseases Research

Brief review of the mRNA vaccines COVID-19

mRNA 백신 COVID-19에 대한 간략한 검토

Review

Published on 2021-06-012022-09-11
Journal: Inflammopharmacology [Category] SARS, 변종,

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

Afucosylated IgG는 외피 바이러스 반응을 특성화하고 COVID-19 심각성과 상관 관계가 있습니다.

Research Article

Published on 2021-02-262022-09-10
Journal: Science (New York, N.y.) [Category] MERS, SARS, 변종, 진단,

[키워드] acute phase acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 ADCC amplify amplifying anti–SARS-CoV-2 IgG antibody antibody-dependent cellular cytotoxicity anticancer Antigen antigens Antiviral association Attenuated Virus B cell B cell response binding Blood blood cell Blood cells Blood Group C-reactive protein C-reactive protein (CRP cause Cell cellular circumvent Clinical outcome complement Concentration condition conserved coronavirus COVID-19 COVID-19 patient COVID-19 patients Critical Critically ill critically ill COVID-19 patients cytokine Cytokine storm dengue virus destruction determined by disparate domain domains elevated Exacerbation example excessive inflammation Fc receptor Fc receptors FcγRIIIa foreign antigen foreign antigens fucose functions glycoprotein Glycoproteins glycosylation help hepatitis B Hepatitis B virus HIV host cell host cells humans Hypothesis IgG IgG antibody IgG immune response IgG response IgG responses IL-6 Immune cell immune response immune responses Immune-mediated Immunoglobulin Immunoglobulin G in some in vitro individual individuals induce initiate interleukin-6 invading pathogens investigated isotype Macrophage macrophages membrane Mild disease mild symptoms mRNA vaccines myeloid cells natural infection natural killer occur over Pathogens Pathologies pathology Patient patients plasma position proinflammatory Proinflammatory cytokine promote promoted Protective Protein Protein subunit receptor receptors Region report reported required respiratory response responses responses against SARS-CoV-2 Science Seroconversion severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 severe symptom severe symptoms severity strength subclass subunit sugar surface protein target target cell target cells tested therapeutic therapeutic antibodies Treatment Trigger vaccination Vaccinations Vaccine variant Viral Viral load virus viruses with COVID-19 with mild disease
[DOI] 10.1126/science.abc8378 PMC 바로가기 [Article Type] Research Article

Field-Effect Sensors for Virus Detection: From Ebola to SARS-CoV-2 and Plant Viral Enhancers

Plant Science

Published on 2020-11-242022-10-31
Journal: Frontiers in Plant Science [Category] COVID-19,

[키워드] acute respiratory syndrome adapter antibody applied biosensor charged biomolecules clinical sample coronavirus Coronavirus disease 2019 COVID-19 demonstrated diagnostic test drug early diagnosis Ebola electrical element enzyme explained faster field effect functional highest human infectious disease humans intrinsic Label-free detection labeling outbreak Perspective plant plant virus nanoparticle plant VLP tool platform point-of-care Protein subunit receptor repeated SARS-CoV-2 sensor the disease time-consuming Treatment Vaccine Viral diseases Viral particles virus virus detection virus spread viruses
[DOI] 10.3389/fpls.2020.598103 PMC 바로가기 [Article Type] Plant Science

Vaccines to prevent COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING VACCINE Project)

코로나19 예방 백신: 개별 환자 데이터를 포함하는 네트워크 메타 분석을 통한 살아있는 체계적인 검토를 위한 프로토콜(The LIVING VACCINE Project)

Protocol

Published on 2020-11-202022-09-10
Journal: Systematic Reviews [Category] COVID-19, meta-analysis, SARS,

[키워드] active placebo acute respiratory syndrome acute respiratory syndrome coronavirus aggregate data meta-analyses all age groups all-cause mortality analyzed approach assessment assessments best cause CENTRAL certainty certainty of evidence Clinical research clinical trial registries clinical trial registry clinical trials confidence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 database dendritic dendritic cell described development Diagnosis disease Effect events Evidence GRADE identify inactivated include individual patient data meta-analyses life Messenger RNA meta-analyses Mortality network Network meta-analysis non-serious adverse non-serious adverse events not limited observational studies observational study once a week outcome pandemic participant patient data Placebo prevalent Prevent Primary outcomes Protein Protein subunit protocol Quality of life randomized clinical trial randomized clinical trials Research respiratory risk of bia SARS-CoV-2 secondary Secondary outcomes Serious Adverse Events severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread standard care supplementary material systematic review Trial trial sequential analyses Vaccine vaccine for COVID-19 Vaccines Viral Viral vector
[DOI] 10.1186/s13643-020-01516-1 PMC 바로가기 [Article Type] Protocol

The Current Status of COVID-19 Vaccines

Genome Editing

Published on 2020-10-022022-10-31
Journal: Frontiers in Genome Editing [Category] COVID-19,

Defining NELF-E RNA Binding in HIV-1 and Promoter-Proximal Pause Regions

HIV-1 및 프로모터-근위 일시 중지 영역에서 NELF-E RNA 결합 정의

Research Article

Published on 2014-01-162022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] a major addition analyzed association Author binding binding activity binding domain Biochemistry cellular claimed compared complex Consensus conserved contribute downstream Drosophila elongation elongation factor eukaryotic facilitate Factor functional Gene Genes Genome high affinity HIV-1 identify in addition to in vitro Interaction modulate molecular negative nuclear nucleotide nucleotides observé pause POLL promoter Protein protein coding gene protein coding genes Protein subunit Quantitative Recognition Region regulate regulated Regulatory required responsible RNA RNA Polymerase II RNA sequence RNA sequences sequence significant increase subunit Support targets thought transcribed Transcription transcription factor transcription factors transcription start site widespread
[DOI] 10.1371/journal.pgen.1004090 PMC 바로가기 [Article Type] Research Article