severe group – Page 3 – Communicable Diseases Research

Platelet-to-lymphocyte ratio, a novel biomarker to predict the severity of COVID-19 patients: A systematic review and meta-analysis

Original Articles

Published on 2022-02-012022-10-29
Journal: Journal of the Intensive Care Society [Category] COVID-19,

Potential Use of Serum Proteomics for Monitoring COVID-19 Progression to Complement RT-PCR Detection

RT-PCR 검출을 보완하기 위한 COVID-19 진행 모니터링을 위한 혈청 단백질체학의 잠재적 사용

Article

Published on 2022-01-072022-09-11
Journal: Journal of Proteome Research [Category] SARS, 유전자 메커니즘, 치료기술,

[키워드] analyzed approach AUC clinic Clinical practice Course COVID-19 COVID-19 patient COVID-19 progression detection diagnose disease course disease course monitoring effort False negative false negatives high risk inactivated Inactivated serum investigated machine learning machine learning model Magnesium mass spectrometry MONITOR monitoring non-severe cases non-severe group nucleic acid Platelet platelet counts Potential practitioners predict promote Protein proteome proteomics regulated required RNA RT-PCR RT-PCR tests serum Serum protein serum sample serum samples Severe case severe cases severe group Swab symptoms onset the disease viral nucleic acid
[DOI] 10.1021/acs.jproteome.1c00525 PMC 바로가기 [Article Type] Article

Diagnostic value of lactate dehydrogenase in COVID-19: A systematic review and meta-analysis

Article

Published on 2022-01-012022-11-15
Journal: Cardiology journal [Category] 바이오마커,

Spectrum of High Resolution Computed tomography chest findings in PCR positive COVID-19 patients according to duration of infection and CT severity score assessment

Original Article

Published on 2022-01-012022-10-29
Journal: Pakistan Journal of Medical Sciences [Category] COVID-19,

[키워드] age Analysis association calculated Chest Chi-square Clinical features conducted consolidation coronavirus disease COVID-19 COVID-19 patient CT Severity Score (CT-SS) disease severity distribution Duration of infection effective evaluate females GGO Ground Glass Opacity (GGO) hallmark High resolution computed tomography (HRCT) HRCT late stage lung male manifestation Mild Patient PCR positive prevalent radiologist radiology department ranged reported Resolution Retrospective study ROC Curve RT-PCR positive patient severe disease severe group severity severity of COVID-19 Severity of disease Spectrum staging symptom onset threshold value tomography Total Variation were used
[DOI] 10.12669/pjms.38.1.4204 PMC 바로가기 [Article Type] Original Article

Association between serum inflammatory parameters and the disease severity in COVID‐19 patients

COVID -19 환자의 혈청 염증 파라미터와 질병 중증도 사이의 연관성

Research Article

Published on 2021-12-072022-08-31
Journal: Journal of Clinical Laboratory Analysis [Category] 바이오마커,

[키워드] age analyzed Blood blood test blood tests C‐reactive protein causative agent clinician correlation count COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 criteria CRP Cytokines develop diagnosed difference disease disease severity enrolled erythrocyte sedimentation erythrocyte sedimentation rate ESR evaluate Gender groups help ICU admission IL‐6 IL‐6 increase in Inflammatory cytokine Inflammatory cytokines Inflammatory marker inflammatory markers inflammatory parameter Iran lymphocyte Lymphocytes marker measurement mild symptoms MONITOR Most patient Most patients neutrophil Neutrophils no significant difference Novel coronavirus objective Patient patients predict Prognosis Result SARS‐CoV‐2 SARS‐CoV‐2 sedimentation rate serum Serum level serum levels severe cases severe group Severe patient severe patients severity severity and prognosis significant decrease significant difference significant differences significantly higher the disease TNF‐α TNF‐α two group two groups
[DOI] 10.1002/jcla.24162 PMC 바로가기 [Article Type] Research Article

Investigation of the impact of SARS-CoV infection on the immunologic status and lung function after 15 years

15 년 후 면역 상태 및 폐 기능에 대한 SARS-COV 감염의 영향에 대한 조사

Research

Published on 2021-11-242022-09-01
Journal: BMC Infectious Diseases [Category] MERS, SARS, 임상, 진단, 치료기술,

[키워드] Abnormalities abnormality airway Analysis benefit beta-coronavirus caused Chest CT Complete components coronavirus detect disease onset dysfunction Effect ELISA enrolled Epidemic evaluated globin healthcare worker HRCT IgG antibodies IgG antibody immune function immune memory immune system immune systems investigation lung lung damage Lung function mMRC N protein non-severe group Post-infection Protein Pulmonary function test Pulmonary function tests pulmonary rehabilitation RBD protein Regulatory T cell Result S-RBD SARS-CoV SARS-CoV infection SARS-CoV specific IgG antibody SARS-CoV-2 pandemic sera Serum level Severe acute respiratory syndrome (SARS) severe group specific IgG antibodies subgroup analysis subject subjects Survivors T cell T regulatory cell T regulatory cells Trial registration university was used were infected
[DOI] 10.1186/s12879-021-06881-3 PMC 바로가기 [Article Type] Research

Brescia-COVID Respiratory Severity Scale (BRCSS) and Quick SOFA (qSOFA) score are most useful in showing severity in COVID-19 patients

Article

Published on 2021-11-082022-10-04
Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 치료법,

[키워드] 95% CI Admission adopted age analyses assessment AUC Biomarkers calculation Clinical outcome Clinicians Coronavirus disease 2019 COVID-19 COVID-19 patient Critical Deceased determine disease severity evaluated failure Guidance hemophagocytic syndrome High-risk patients highest Hospital admission immunology improve clinical outcome independent infiltration Intervention IQR median Medical research men Microbiology multivariate analyses multivariate logistic regression non-severe group parameter Patient patients patients with COVID-19 predict Predictive Prognosis qSOFA reactive respiratory Risk factors scale scoring system severe COVID-19 severe disease severe group severity SOFA surviving patient the disease the patient two group was determined World Health Organization
[DOI] 10.1038/s41598-021-01181-x PMC 바로가기 [Article Type] Article

437. Longitudinal Plasma Cytokine Profiles Differentiating COVID-19 Severity Groups

Poster Abstracts

Published on 2021-11-042022-10-29
Journal: Open Forum Infectious Diseases [Category] COVID-19,

[키워드] acute COVID-19 acute respiratory syndrome age analyzed assigned association Asymptomatic blood sample cause children Clinical severity cohorts consultant convalescent convalescent plasma coronavirus coronavirus disease COVID-19 criteria CSS cytokine cytokine level cytokine profile Cytokine storm syndrome Disease progression elevated enrolled figure GCSF group hospital Hospitalization Hospitalized IL-10 IL-15 IL-8 Inc Infection Inflammatory Inflammatory response IP-10 Joshua less longitudinal Mild mild cases MIP-1β MIS-C moderate moderate-severe nothing participant Participants Patient PCR Phenotypes plasma sample polymerase chain positive profile Prospective Quantitative response Result SARS-CoV-2 SARS-CoV-2 PCR severe cases severe COVID-19 severe group Severe patient severity Severity Score significant difference syndrome Temporal tested Thomas timepoint timepoints Treatment Wolf
[DOI] 10.1093/ofid/ofab466.636 PMC 바로가기 [Article Type] Poster Abstracts

Assessment of antiphospholipid antibodies and calprotectin as biomarkers for discriminating mild from severe COVID-19

경증에서 중증 COVID-19를 구별하기 위한 바이오마커로서의 항인지질 항체 및 칼프로텍틴의 평가

Article

Published on 2021-11-012022-09-11
Journal: Journal of Clinical Laboratory Analysis [Category] MERS, SARS, 바이오마커, 진단, 치료기술,

[키워드] acute respiratory distress acute respiratory distress syndrome antibodies antibody anticardiolipin antibodies anticardiolipin antibody antiphospholipid antibodies assessment association Biomarker C-reactive protein C-reactive protein (CRP calprotectin CD4 clinically coronavirus coronavirus disease correlation COVID-19 COVID-19 patient COVID-19 patients CRP CRP level CRP levels detectable Detection limit elevated ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated ferritin groups healthy control healthy controls help highest Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients IgM immunoassay IMPROVE Inflammatory laboratory parameter lymphocyte Lymphocyte count management Mild moderate multiplex negative correlation neutrophil Neutrophil-to-lymphocyte ratio no significant differences not differ outcome oxygenation status parameter pathway peak levels Prevalence procalcitonin proportion respiratory distress Respiratory distress syndrome sera severe COVID-19 severe group severity significant differences significantly significantly higher syndrome T cells two group two groups were measured
[DOI] 10.1002/jcla.24004 PMC 바로가기 [Article Type] Article

An epigenome-wide DNA methylation study of patients with COVID-19

COVID-19 환자의 후성유전체 DNA 메틸화 연구

Article

Published on 2021-11-012022-09-11
Journal: Annals of human genetics [Category] MERS, SARS, 바이오마커, 유전자 메커니즘, 진단,

[키워드] Above analyses Analysis biological processes can be used CHN2 CHST15 conducted COVID-19 COVID-19 patient COVID-19 patients CPLX2 CRHR2 DCAKD disease severities DNA DNA methylation downregulated duplicates eliminating EpiC Epigenetic epigenetic regulation expression function functions Genes GNAI2 GNAS GNG7 healthy subject healthy subjects HECW1 highest highly pathogenic hub genes HYAL1 Illness severity Illumina immune system investigated methylated MIR510 molecular mechanism molecular mechanisms pathophysiology pathway Pathways patients with COVID-19 PDE11A PPI PRKAG2 PRKCZ progression promoter region public health Regulation SARS-CoV-2 SARS-COV-2 infection selected Sequencing severe group Signal transduction SMG6 were used
[DOI] 10.1111/ahg.12440 PMC 바로가기 [Article Type] Article