investigated(5) Pathways(5) healthy subjects(5) downregulated(5) disease severities(5) COVID-19(5) patients with COVID-19(5) Genes(5) hub genes(5) DCAKD(5) DNA(5) PDE11A(5) expression(5) selected(5) Analysis(5) Regulation(5) were used(5) molecular mechanisms(5) eliminating(5) highly pathogenic(5) SARS-COV-2 infection(5) CPLX2(5) molecular mechanism(5) HECW1(5) DNA methylation(5) SMG6(5) Signal transduction(5) conducted(5) COVID-19 patient(5) severe group(5)