Decreased Fetal Movements: A Sign of Placental SARS-CoV-2 Infection with Perinatal Brain Injury태아 운동 감소 : 주 산기 뇌 손상으로 태반 SARS-COV-2 감염의 징후Case Reports Published on 2021-12-152022-09-10 Journal: Viruses [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus antibody Brain brain injury Caesarean section coronavirus COVID-19 cytoplasmic Decreased fetal fetal movements gestation infect Injury leukomalacia Mild MRI Neonatal COVID-19 Neonate neurosonography Perinatal Placenta placental respiratory RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 spike severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 SIGN Transmission vertical transmission [DOI] 10.3390/v13122517 PMC 바로가기 [Article Type] Case Reports
ACE2, TMPRSS2, and L-SIGN Expression in Placentae From HIV-Positive Pregnancies Exposed to Antiretroviral Therapy-Implications for SARS-CoV-2 Placental InfectionSARS-CoV-2 태반 감염에 대한 항레트로바이러스 요법에 노출된 HIV 양성 임신의 태반에서 ACE2, TMPRSS2 및 L-SIGN 발현Article Published on 2021-12-082022-09-11 Journal: The Journal of Infectious Diseases [Category] SARS, 치료제, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus AIDS angiotensin Antiretroviral therapy ART binding Black race Chain Reaction coexpressed contribute coronavirus COVID-19 detrimental expression female groups HIV HIV infection HIV protease inhibitors HIV-uninfected hyperinflammation infant sex L-SIGN lower expression mRNA level mRNA levels Neonate Placenta placental polymerase chain polymerase chain reaction pregnant women priming protease Protease inhibitor protease TMPRSS2 Quantitative quantitative polymerase chain reaction race receptor receptor ACE2 reduced Renin renin-angiotensin system SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 SIGN significantly significantly higher Spike protein susceptibility the spike protein TMPRSS2 TMPRSS2 level TMPRSS2 levels viral entry with HIV women [DOI] 10.1093/infdis/jiab166 PMC 바로가기 [Article Type] Article
Vital Signs Prediction for COVID-19 Patients in ICUArticle Published on 2021-12-052022-10-29 Journal: Sensors (Basel, Switzerland) [Category] Coronavirus, SARS, [키워드] approach approaches average blood pressure COVID-19 diastolic ENhance FIVE health condition ICU ICU patient ICU Patients include investigated kNN-LS-SVM monitoring system observation oxygen saturation predict predicted prediction Predictive Predictive model predictor pulse SIGN tested Vital vital sign vital signs vital signs prediction [DOI] 10.3390/s21238131 PMC 바로가기 [Article Type] Article
Post-Acute Sequelae of COVID-19 and Cardiovascular Autonomic Dysfunction: What Do We Know?Review Published on 2021-11-152022-10-30 Journal: Journal of Cardiovascular Development and Disease [Category] COVID-19, [키워드] Autoimmunity autonomic cardiovascular cardiovascular autonomic dysfunction chest pain COVID COVID-19 dysfunction Dyspnea dysregulation Epidemiology Evidence fatigue Health include long COVID syndrome mechanism nervous system orthostatic PASC Patient pharmacological intervention Post-acute sequelae postural orthostatic tachycardia reduced SARS-CoV-2 SARS-COV-2 infection SIGN Symptom Syncope syndrome Tachycardia Tolerance treat [DOI] 10.3390/jcdd8110156 PMC 바로가기 [Article Type] Review
Effect of vaccination against COVID-19 spreadingCovid-19 확산에 대한 예방 접종의 영향Original Article Published on 2021-11-112022-09-10 Journal: Proceedings of the Japan Academy. Series B, Physic [Category] MERS, 변종, [키워드] Analysis analyzed change concerning contagious COVID-19 Effect effective initial Japan Older parameter Preliminary data PROC SARS-CoV-2 Section Ser SIGN spreading strength Tokyo vaccination vaccination against COVID-19 vaccination schedule Vaccinations variant variants variants of SARS-CoV-2 virus [DOI] 10.2183/pjab.97.027 PMC 바로가기 [Article Type] Original Article
COVID-19 and Its Repercussions on Oral Health: A ReviewCOVID-19와 구강 건강에 미치는 영향: 검토Review Published on 2021-11-012022-09-10 Journal: Medicina [Category] MERS, SARS, 변종, 치료기술, [키워드] abdominal pain accompanied Adverse reaction Adverse reactions Anosmia candidiasis co-morbidities condition coronavirus COVID-19 COVID-19 patient COVID-19 patients dental medicine Deterioration diarrhea distress dysgeusia enanthema erythematous fatigue geographic tongue gravity hairy tongue Health Organization Hemorrhagic Hospitalized Hypogeusia include Infection involved knowledge lesion lesions life-threatening manifestation Manifestations morbidities mucosal mucosal lesions nasal congestion nausea nausea/vomiting necrotic ocular ocular symptoms oral Oral hygiene oral lesions oral manifestations pandemic patients with COVID-19 periodontal disease petechiae Poor oral hygiene presenting Repercussion reported respiratory distress review runny nose SARS-CoV-2 Severe infection SIGN simplex Symptom Symptoms temporomandibular disorders tongue Viral viral infection viral variant Viral variants vomiting World Health Organization Wuhan Wuhan, China [DOI] 10.3390/medicina57111189 PMC 바로가기 [Article Type] Review
Hematuria as an Early Sign of Multisystem Inflammatory Syndrome in Children: A Case Report of a Boy With Multiple Comorbidities and Review of LiteraturePediatrics Published on 2021-10-272022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] abdominal pain Antibiotic therapy arrhythmia Asymptomatic Boy Case report children Clinical course clinical feature clinical suspicion criteria CRP cultures D-dimer defined Diagnosis disorder dysfunction elevated elicited ESR Fever fibrinogen Hematuria IgG SARS-CoV-2 antibodies include Inflammation Inflammatory inflammatory condition instantaneous Intravenous immunoglobulin Kawasaki disease kidney Laboratory literature manifestation marker mechanism microbial Mild MIS-C Multiple multiple comorbidity multisystem inflammatory syndrome in children (MIS-C) outcome Patient pediatric positive Rash report reported review SARS-CoV-2 SARS-COV-2 infection SIGN supported Symptom syndrome Treatment ventricular virus vomiting while with COVID-19 worsened [DOI] 10.3389/fped.2021.760070 PMC 바로가기 [Article Type] Pediatrics
SARS-CoV-2 Impairs Dendritic Cells and Regulates DC-SIGN Gene Expression in TissuesSARS-CoV-2는 수지상 세포를 손상시키고 조직에서 DC-SIGN 유전자 발현을 조절합니다Article Published on 2021-08-262022-09-12 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 진단, [키워드] ACE2 airway ANXA1 Blood CD22 cDCs coronavirus SARS-CoV-2 COVID-19 COVID-19 patient COVID-19 patients dataset DC-SIGN DCs dendritic cell dendritic cells downregulation Gene Expression healthy controls host receptor Host receptors immature immune responses indicate innate immune response innate immune responses L-SIGN lung lung DC Lungs MHCII Mild modulation observation pathogenic pDCs plasmacytoid DC plasmacytoid DCs provide SARS Coronavirus SARS coronaviruses SARS-CoV-2 screened Severe case severe cases severe COVID-19 SIGN Single Cell stimulate transcriptomic upper airway [DOI] 10.3390/ijms22179228 PMC 바로가기 [Article Type] Article
The Post-Acute Phase of SARS-CoV-2 Infection in Two Macaque Species Is Associated with Signs of Ongoing Virus Replication and Pathology in Pulmonary and Extrapulmonary Tissues두 개의 원숭이 종에서 SARS-COV-2 감염의 급성기 후에는 폐 및 외부 조직에서 진행중인 바이러스 복제 및 병리의 징후와 관련이 있습니다.Article Published on 2021-08-232022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, [키워드] activated acute phase animal models Computed tomography Conjunctiva consequence COVID-19 cynomolgus macaque cynomolgus macaques detectable Extrapulmonary extrapulmonary tissue feces heart histological Histopathology humans immune activation Infection investigated lesion lung lung tissue Lungs Lymph node lymph nodes macaque macaques Messenger RNA necropsy NHPs non-human primates nose nose and throat phase positron emission Positron emission tomography pulmonary pulmonary lesion pulmonary lesions respiratory respiratory tract rhesus salivary salivary gland SARS-CoV-2 SARS-COV-2 infection SIGN Specy tissue sample tissue samples tomography tracheobronchial tracheobronchial lymph nodes Viral Viral RNA virus replication [DOI] 10.3390/v13081673 PMC 바로가기 [Article Type] Article
A proteome-wide genetic investigation identifies several SARS-CoV-2-exploited host targets of clinical relevance프로테옴 전반에 걸친 유전자 조사는 임상 관련성이 있는 여러 SARS-CoV-2 악용 숙주 표적을 식별합니다.Research Article Published on 2021-08-172022-09-10 Journal: eLife [Category] MERS, SARS, 유전자 메커니즘, [키워드] ABO Accepted Affect affecting age Alpha Analysis Antiviral Apoptosis applied approach arising association Author cause CD209 clinical trial contribute COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 patient COVID-19 phenotypes datasets DC-SIGN death Demographic factors demonstrated disease severity evade explain Factor Factors funding Gender gene expression level gene mutation Genetic genetic colocalization genetic profile healthy individuals help Host host cells host protein host proteins Human identify identifying IL-6R immune immune response individual individuals infect Infection interact Interaction involved Karim MAK mechanism Medical Research Council mendelian randomization minor symptom minor symptoms molecular mutate natural experiment new strain no symptom no symptoms OAS1 open Open Access opens Patient patients with COVID-19 pleiotropic Potential treatment precursor predict predicted Probability PROTECT Protein Proteins proteome provide randomisation reaction receptor receptor protein reduce Research response responsible risk SARS-CoV-2 severe COVID-19 severity of COVID-19 SIGN Spike protein Strains submission susceptibility susceptible susceptible hosts Symptoms target targets the spike protein the strongest Therapeutics treat Treatment Trigger unique unit variety virus virus strains viruses Wellcome Trust with COVID-19 [DOI] 10.7554/eLife.69719 PMC 바로가기 [Article Type] Research Article