Evaluation of the microbial reduction efficacy and perception of use of an ozonized water spray disinfection technology Research Published on 2022-07-292022-10-05 Journal: Scientific Reports [Category] 진단, [키워드] activities Analysis approach approval association Community contaminated surfaces contribute effective Efficacy evaluated indicated infections infectious agent Log reduction microbial pathogen PPM preventive measure Protective reduce reduction remained Spread tested Transport Volunteer volunteers [DOI] 10.1038/s41598-022-16953-2 [Article Type] Research
Safety and immunogenicity of anti-SARS CoV-2 vaccine SOBERANA 02 in homologous or heterologous scheme: Open label phase I and phase IIa clinical trials동종 또는 이종 체계에서 항 SARS CoV-2 백신 SOBERANA 02의 안전성 및 면역원성: 공개 라벨 임상 1상 및 2a상 임상 시험Clinical Trial Published on 2022-07-292022-09-11 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, [키워드] adaptive adverse event Anti-RBD IgG Antigen clinical trial clinical trials conjugate Conjugate vaccine COVID-19 COVID-19 vaccine D614G delta variant dose doses elicited ELISA evaluate evaluated frequencies Frequency hACE2 Heterologous heterologous immunization Heterologous immunization scheme homologous homologous or heterologous IgG IgG ELISA IIa immune response immune responses immunogenic immunogenicity Immunological response Interaction local pain molecular neutralization neutralized Neutralizing antibodies neutralizing antibody Open-label outcome Panel performed phase Phase I phase IIa Primary outcome progressed protocol protocols RBD receive receiving reduction reported Safe Safety SARS-CoV-2 secondary outcome selected Specific T-cell response subjects Subunit vaccine T-cell T-cell Response T-cells Tetanus tetanus toxoid trials Vaccine variant Volunteer volunteers [DOI] 10.1016/j.vaccine.2022.05.082 PMC 바로가기 [Article Type] Clinical Trial
Alterations in the molecular composition of COVID-19 patient urine, detected using Raman spectroscopic/computational analysis라만 분광/전산 분석을 사용하여 감지한 COVID-19 환자 소변의 분자 구성 변화Article Published on 2022-07-182022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Abnormalities Accuracy affected alteration Analysis analyzed Bladder cancer Care Chain Reaction Chromatography Clinical pathology collected complex component components computational analysis Contact contact with contributing to correlation correlations COVID-19 COVID-19 disease COVID-19 patient creatinine defined detect determine disease disease severity EGFR elevated fingerprint gas chromatography Gas Chromatography-Mass Spectrometry GC-MS glomerular filtration rate healthy healthy individual healthy individuals Hospitalized HPLC identify in urine include Infection Inflammatory liquid Liquid chromatography Long mass spectrometry metabolomic analysis Mild moderate molecular Negative predictive value pathology Patient patients performance Peritoneal dialysis positive Positive predictive value Predictive value Raman spectroscopy random ranged reaction representing respiratory RT-PCR SARS-CoV-2 virus sensitivity serum creatinine severity specificity specimen specimens Spectrometry Symptom symptomatic tested Urinalysis Urine urine specimens Viral Volunteer with COVID-19 [DOI] 10.1371/journal.pone.0270914 PMC 바로가기 [Article Type] Article
ACTIVATE-2: A Double-Blind Randomized Trial of BCG Vaccination Against COVID-19 in Individuals at RiskACTIVATE-2: 위험에 처한 개인에서 COVID-19에 대한 BCG 백신 접종의 이중 맹검 무작위 시험Randomized Controlled Trial Published on 2022-07-052022-09-12 Journal: Frontiers in Immunology [Category] MERS, 임상, 진단, [키워드] 1:1 95% CI acute respiratory syndrome Against anti-SARS-CoV-2 anti-SARS-CoV-2 antibody antibodies approach Bacillus BCG BCG vaccination benefit clinical criteria Comorbidities controls coronavirus coronavirus disease COVID-19 COVID-19 pandemic develop Diagnosis double-blind trial Efficacy eight elderly vaccination end point evaluated Follow-up Hospitalization Immunity incidence of COVID-19 individual Infection Intervention Laboratory MOST multicenter Occurrence Older participant Patient patients older Placebo positive Randomized recipient reduced reduction respiratory infections Result risk SARS-CoV-2 the placebo group trained immunity Trial vaccination Vaccine Volunteer [DOI] 10.3389/fimmu.2022.873067 PMC 바로가기 [Article Type] Randomized Controlled Trial
Stewardship of COVID-19 volunteers by nested trial designDiscussion Published on 2022-07-052022-10-05 Journal: The Lancet. Infectious Diseases [Category] COVID19(2023년), SARS, 임상, [키워드] COVID-19 Trial Volunteer [DOI] 10.1016/S1473-3099(22)00429-7 [Article Type] Discussion
An exploratory analysis of the response to ChAdOx1 nCoV-19 (AZD1222) vaccine in males and females남성과 여성에서 ChAdOx1 nCoV-19(AZD1222) 백신에 대한 반응에 대한 탐색적 분석Article Published on 2022-07-012022-09-11 Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 95% CI Academy adjusted age and sex All participant All participants anti-SARS-CoV-2 anti-Spike IgG AstraZeneca AZD1222 both sexes Brazil Cellular immune response ChAdOx1 ChAdOx1 nCoV-19 Chinese clinical Clinical research clinical trials Coalition Council COVID-19 COVID-19 vaccine COVID-19 vaccines defined dose doses Efficacy endpoints Engineering enrolled Evidence evidence of Exploratory analysis fatigue female females Fever first dose Follow-up foundation funding generate GMR greater headache humoral immune responses immunogenicity immunogenicity data immunological individual Innovation interaction term ISRCTN Linear model linear models log-transformed logistic regression models majority male males Medical Science NAAT nCoV network neutralisation assay NIHR no evidence of nucleic acid nucleic acid amplification nucleic acid amplification test Oxford participant Participants primary endpoint randomised randomised controlled trial reaction reactogenicity receive Registered Regression model reported SARS-COV-2 infection Science Sex Sex-differences shown single-blind South spike IgG Standard dose statistically significant difference Superior symptomatic SARS-CoV-2 infection systemic reaction Telle the primary endpoint titre trial participants vaccination Vaccine vaccine efficacy Vaccines Valley Volunteer [DOI] 10.1016/j.ebiom.2022.104128 PMC 바로가기 [Article Type] Article
Antimicrobial Activity of the Serum before and after Vaccination with EpiVacCoronaEpiVacCorona 백신 접종 전과 후 혈청의 항균 활성Article Published on 2022-07-012022-09-12 Journal: Bulletin of experimental biology and medicine [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] activity antimicrobial antimicrobial activity antimicrobial peptide antimicrobial peptides Cell coronavirus correlated demonstrated EpiVacCorona evaluated expression expression of gene fraction initial inverse correlation Normal distribution PCR peptides reverse transcription SARS-CoV-2 antigen sera serum specific IgG antibodies specific IgG antibody Total vaccination Vaccine Volunteer was measured [DOI] 10.1007/s10517-022-05548-6 PMC 바로가기 [Article Type] Article
Comparison of IgA, IgG, and Neutralizing Antibody Responses Following Immunization With Moderna, BioNTech, AstraZeneca, Sputnik-V, Johnson and Johnson, and Sinopharm’s COVID-19 VaccinesModerna, BioNTech, AstraZeneca, Sputnik-V, Johnson and Johnson 및 Sinopharm의 COVID-19 백신을 사용한 면역 후 IgA, IgG 및 중화 항체 반응의 비교Article Published on 2022-06-212022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] age Analysis analyzed antibody Antibody titers AstraZeneca automated binding blood sample categories category Combination comparable Correlation analysis COVID-19 COVID-19 vaccines demonstrated DNA dose doses effective ELISA expression group groups Heterologous highest homologous IgA IgG immunogenic investigated lowest moderate Moderna mRNA vaccine negative correlation neutralization Neutralizing Neutralizing antibodies neutralizing antibody Older reactogenicity response sandwich ELISA SARS-CoV-2 sera significant increase significantly higher Sinopharm Spearman specific neutralizing antibody statistically Trial vaccination Vaccination strategy Vaccine vaccinee vaccinees vectored vaccine virus Virus neutralization Virus-specific IgG Volunteer [DOI] 10.3389/fimmu.2022.917905 PMC 바로가기 [Article Type] Article
Magnetofluid-Integrated Multicolor Immunochip for Visual Analysis of Neutralizing Antibodies to SARS-CoV-2 VariantsSARS-CoV-2 변이체에 대한 중화 항체의 시각적 분석을 위한 자기유체 통합 다색 면역칩Article Published on 2022-06-142022-09-11 Journal: Analytical Chemistry [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, 치료제, [키워드] affected Analysis antibody antibody levels booster changes in connection develop effective Epidemic equipment gold Health identify immune response immunization immunoassay Infection life magnetic bead Magnetic beads medical resource Medical resources mineral oil Multicolor Neutralizing antibodies neutralizing antibody platform point-of-care PROTECT provide reflected SARS-CoV-2 SARS-CoV-2 virus sensitivity specificity Spread substrate the immunoassay Vaccine Vaccine immunization vertical direction Visual Volunteer [DOI] 10.1021/acs.analchem.2c01260 PMC 바로가기 [Article Type] Article
Towards Multimodal Equipment to Help in the Diagnosis of COVID-19 Using Machine Learning Algorithms기계 학습 알고리즘을 사용하여 COVID-19 진단에 도움이 되는 다중 모드 장비를 향하여Article Published on 2022-06-082022-09-11 Journal: Sensors (Basel, Switzerland) [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy Algorithm applied Area AUC biomedical sensors body temperature can be used chain Chain Reaction collected cough coughs COVID-19 COVID-19 infection COVID-19 pandemic Curve dataset decision Decision tree detect Diagnosis diagnosis of COVID-19 equipment heart rate help individual Infection lab machine learning Machine learning algorithms Medical assistant Metrics occur oxygen oxygen saturation polymerase chain reaction reaction real-time polymerase chain reaction released reported respiratory diseases respiratory droplet Respiratory droplets RT-PCR SARS-CoV-2 virus significant delay sneezes speech SpO2 support vector machine SUS System System Usability Scale Telemedicine the SARS-CoV-2 virus tree Usability virus Volunteer [DOI] 10.3390/s22124341 PMC 바로가기 [Article Type] Article